Biotinylated probe isolation of targeted gene region improves detection of T790M epidermal growth factor receptor mutation via peptide nucleic acid-enriched real-time PCR

Clinical Chemistry

Volumn 57, Issue 5, 2011, Pages 770-773

  Li, Jin ^a   Jänne, Pasi A ^a   Makrigiorgos, G Mike ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GENOMIC DNA; METHIONINE; OLIGONUCLEOTIDE; PEPTIDE NUCLEIC ACID; STREPTAVIDIN; THREONINE;

ALLELE; ARTICLE; CONTROLLED STUDY; DILUTION; DNA ISOLATION; EXON; GENE AMPLIFICATION; GENE MUTATION; HUMAN; HUMAN CELL; MALE; MUTANT; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; WILD TYPE;

BIOTIN; CELL LINE, TUMOR; DNA; DRUG RESISTANCE, NEOPLASM; HUMANS; LIMIT OF DETECTION; LUNG NEOPLASMS; MALE; MOLECULAR PROBES; MUTATION; OLIGONUCLEOTIDES; PEPTIDE NUCLEIC ACIDS; POLYMERASE CHAIN REACTION; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 79956076541     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2010.157784     Document Type: Article

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