메뉴 건너뛰기




Volumn 52, Issue 5, 2011, Pages 2556-2564

High-resolution, noninvasive, two-photon fluorescence measurement of molecular concentrations in corneal tissue

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCEIN DERIVATIVE; FLUORESCEIN SODIUM; RIBOFLAVIN;

EID: 79956060409     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-6620     Document Type: Article
Times cited : (33)

References (50)
  • 2
    • 35148894469 scopus 로고    scopus 로고
    • Coated microneedles for drug delivery to the eye
    • Jiang J, Gill HS, Ghate D, et al. Coated microneedles for drug delivery to the eye. Invest Ophthalmol Vis Sci. 2007;48:4038-4043.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 4038-4043
    • Jiang, J.1    Gill, H.S.2    Ghate, D.3
  • 3
    • 37849031854 scopus 로고    scopus 로고
    • Superficial punctate fluorescein staining of the ocular surface
    • Ward KW. Superficial punctate fluorescein staining of the ocular surface. Optom Vision Sci. 2008;85:8-16.
    • (2008) Optom Vision Sci , vol.85 , pp. 8-16
    • Ward, K.W.1
  • 4
    • 0242695813 scopus 로고    scopus 로고
    • A novel grading method for superficial punctate keratopathy magnitude and its correlation with corneal epithelial permeability
    • Kazunori Miyata, Shiro Amano, Mitsuru Sawa, Teruo Nishida. A novel grading method for superficial punctate keratopathy magnitude and its correlation with corneal epithelial permeability. Arch Ophthalmol. 2003;121:1537-1539.
    • (2003) Arch Ophthalmol , vol.121 , pp. 1537-1539
    • Miyata, K.1    Amano, S.2    Sawa, M.3    Nishida, T.4
  • 5
    • 0022505108 scopus 로고
    • Measurement of fluorescein and fluorescein monoglucuronide in the living human eye
    • McLaren J, Brubaker R. Measurement of fluorescein and fluorescein monoglucuronide in the living human eye. Invest Ophthalmol Vis Sci. 1986;27:966-974.
    • (1986) Invest Ophthalmol Vis Sci , vol.27 , pp. 966-974
    • McLaren, J.1    Brubaker, R.2
  • 6
    • 0029930659 scopus 로고    scopus 로고
    • A new method for determining corneal epithelial barrier to fluorescein in humans
    • Joshi A, Maurice D, Paugh J. A new method for determining corneal epithelial barrier to fluorescein in humans. Invest Ophthalmol Vis Sci. 1996;6:1008-1016.
    • (1996) Invest Ophthalmol Vis Sci , vol.6 , pp. 1008-1016
    • Joshi, A.1    Maurice, D.2    Paugh, J.3
  • 7
    • 33747036952 scopus 로고    scopus 로고
    • How has confocal microscopy helped us in refractive surgery?
    • Kaufman SC, Kaufman HE. How has confocal microscopy helped us in refractive surgery? Curr Opin Ophthalmol. 2006;17:380-388.
    • (2006) Curr Opin Ophthalmol , vol.17 , pp. 380-388
    • Kaufman, S.C.1    Kaufman, H.E.2
  • 8
    • 63649148290 scopus 로고    scopus 로고
    • In vivo confocal microscopy, an inner vision of the cornea-a major review
    • Guthoff RF, Zhivov A, Stachs O. In vivo confocal microscopy, an inner vision of the cornea-a major review. Clin Exp Ophthalmol. 2009;37:100-117.
    • (2009) Clin Exp Ophthalmol , vol.37 , pp. 100-117
    • Guthoff, R.F.1    Zhivov, A.2    Stachs, O.3
  • 9
    • 33751114159 scopus 로고    scopus 로고
    • Clinical use of in vivo confocal microscopy through focusing in corneal refractive surgery
    • Li Y, Zhang X, Zhong LXY, Jin YM. Clinical use of in vivo confocal microscopy through focusing in corneal refractive surgery. J Refract Surg. 2006;22:S1041-S1046.
    • (2006) J Refract Surg , vol.22
    • Li, Y.1    Zhang, X.2    Zhong, L.X.Y.3    Jin, Y.M.4
  • 11
    • 77958489783 scopus 로고    scopus 로고
    • Correlation between UV absorption and riboflavin concentration in different depths of the cornea in CXL
    • Spoerl E, Raiskup F, Kampik D, Geerling G. Correlation between UV absorption and riboflavin concentration in different depths of the cornea in CXL. Curr Eye Res. 2010;35:1040-1041.
    • (2010) Curr Eye Res , vol.35 , pp. 1040-1041
    • Spoerl, E.1    Raiskup, F.2    Kampik, D.3    Geerling, G.4
  • 12
    • 39749122245 scopus 로고    scopus 로고
    • Three-dimensional chemical concentration maps in a microfluidic device using two-photon absorption fluorescence imaging
    • Schafer D, Gibson EA, Amir W, et al. Three-dimensional chemical concentration maps in a microfluidic device using two-photon absorption fluorescence imaging. Opt Lett. 2007;32:2568-2570.
    • (2007) Opt Lett , vol.32 , pp. 2568-2570
    • Schafer, D.1    Gibson, E.A.2    Amir, W.3
  • 13
    • 0029843925 scopus 로고    scopus 로고
    • Twophoton excited lifetime imaging of autofluorescence in cells during UVA and NIR photostress
    • Konig K, So PTC, Mantulin WW, Tromberg BJ, Gratton E. Twophoton excited lifetime imaging of autofluorescence in cells during UVA and NIR photostress. JMicrosc. 1996;183:197-204.
    • (1996) JMicrosc , vol.183 , pp. 197-204
    • Konig, K.1    So, P.T.C.2    Mantulin, W.W.3    Tromberg, B.J.4    Gratton, E.5
  • 14
    • 0032820395 scopus 로고    scopus 로고
    • Long-term twophoton fluorescence imaging of mammalian embryos without compromising viability
    • Squirrell JM, Wokosin DL, White JG, Bavister BD. Long-term twophoton fluorescence imaging of mammalian embryos without compromising viability. Nat Biotechnol. 1999;17:763-767.
    • (1999) Nat Biotechnol , vol.17 , pp. 763-767
    • Squirrell, J.M.1    Wokosin, D.L.2    White, J.G.3    Bavister, B.D.4
  • 15
    • 0028102269 scopus 로고
    • Two-photon molecular excitation provides intrinsic 3-dimensional resolution for laser-based microscopy and microphotochemistry
    • Williams R, Piston D, Webb W. Two-photon molecular excitation provides intrinsic 3-dimensional resolution for laser-based microscopy and microphotochemistry. FASEB J. 1994;8:804-813.
    • (1994) FASEB J , vol.8 , pp. 804-813
    • Williams, R.1    Piston, D.2    Webb, W.3
  • 16
    • 24744455720 scopus 로고    scopus 로고
    • Two-photon 3-D mapping of ex vivo human skin endogenous fluorescence species based on fluorescence emission spectra
    • Laiho LH, Pelet S, Hancewicz TM, Kaplan PD, So PTC. Two-photon 3-D mapping of ex vivo human skin endogenous fluorescence species based on fluorescence emission spectra. J Biomed Opt. 2005;10:10.
    • (2005) J Biomed Opt , vol.10 , pp. 10
    • Laiho, L.H.1    Pelet, S.2    Hancewicz, T.M.3    Kaplan, P.D.4    So, P.T.C.5
  • 17
    • 0242353872 scopus 로고    scopus 로고
    • Nonlinear magic: Multiphoton microscopy in the biosciences
    • Zipfel WR, Williams RM, Webb WW. Nonlinear magic: multiphoton microscopy in the biosciences. Nat BioTechnol. 2003;21: 1368-1376.
    • (2003) Nat BioTechnol , vol.21 , pp. 1368-1376
    • Zipfel, W.R.1    Williams, R.M.2    Webb, W.W.3
  • 18
    • 77955866438 scopus 로고    scopus 로고
    • Influence of corneal collagen crosslinking with riboflavin and ultraviolet-a irradiation on excimer laser surgery
    • Kampik D, Ralla B, Keller S, Hirschberg M, Friedl P, Geerling G. Influence of corneal collagen crosslinking with riboflavin and ultraviolet-a irradiation on excimer laser surgery. Invest Ophthalmol Vis Sci. 2010;51:3929-3934.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 3929-3934
    • Kampik, D.1    Ralla, B.2    Keller, S.3    Hirschberg, M.4    Friedl, P.5    Geerling, G.6
  • 19
    • 0029164337 scopus 로고
    • Clinical evaluation of corneal epithelial barrier function with slit-lamp fluorophotometer
    • Yokoi N, Kinoshita S. Clinical evaluation of corneal epithelial barrier function with slit-lamp fluorophotometer. Cornea. 1995; 14:485-489.
    • (1995) Cornea , vol.14 , pp. 485-489
    • Yokoi, N.1    Kinoshita, S.2
  • 20
    • 0016325654 scopus 로고
    • Endothelial permeability of the living cornea to fluorescein
    • Ota Y, Mishima S, Maurice DM. Endothelial permeability of the living cornea to fluorescein. Invest Ophthalmol. 1974;13:945-949.
    • (1974) Invest Ophthalmol , vol.13 , pp. 945-949
    • Ota, Y.1    Mishima, S.2    Maurice, D.M.3
  • 21
    • 33746534226 scopus 로고    scopus 로고
    • Fluorophotometry as a diagnostic tool for the evaluation of dry eye disease
    • Fahim M, Haji S, Koonapareddy C, Fan V, Asbell P. Fluorophotometry as a diagnostic tool for the evaluation of dry eye disease. BMC Ophthalmol. 2006;6:20.
    • (2006) BMC Ophthalmol , vol.6 , pp. 20
    • Fahim, M.1    Haji, S.2    Koonapareddy, C.3    Fan, V.4    Asbell, P.5
  • 22
    • 0033822741 scopus 로고    scopus 로고
    • The diagnosis and management of dry eye: A twenty-five-year review
    • Pflugfelder S, Solomon A, Stern M. The diagnosis and management of dry eye: a twenty-five-year review. Cornea. 2000;19:644-649.
    • (2000) Cornea , vol.19 , pp. 644-649
    • Pflugfelder, S.1    Solomon, A.2    Stern, M.3
  • 23
    • 0037795542 scopus 로고    scopus 로고
    • Live tissue intrinsic emission microscopy using multiphotonexcited native fluorescence and second harmonic generation
    • Zipfel WR, Williams RM, Christie R, Nikitin AY, Hyman BT, Webb WW. Live tissue intrinsic emission microscopy using multiphotonexcited native fluorescence and second harmonic generation. Proc Natl Acad Sci U S A. 2003;100:7075-7080.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7075-7080
    • Zipfel, W.R.1    Williams, R.M.2    Christie, R.3    Nikitin, A.Y.4    Hyman, B.T.5    Webb, W.W.6
  • 24
    • 0037405409 scopus 로고    scopus 로고
    • Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus
    • Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol. 2003;135:620-627.
    • (2003) Am J Ophthalmol , vol.135 , pp. 620-627
    • Wollensak, G.1    Spoerl, E.2    Seiler, T.3
  • 25
    • 0141819135 scopus 로고    scopus 로고
    • Endothelial cell damage after riboflavin-ultraviolet-A treatment in the rabbit
    • Wollensak G, Spoerl E, Wilsch M, Seiler T. Endothelial cell damage after riboflavin-ultraviolet-A treatment in the rabbit. J Cataract Refract Surg. 2003;29:1786-1790.
    • (2003) J Cataract Refract Surg , vol.29 , pp. 1786-1790
    • Wollensak, G.1    Spoerl, E.2    Wilsch, M.3    Seiler, T.4
  • 26
    • 0033763826 scopus 로고    scopus 로고
    • In vitro comparison of Chen medium and Optisol-GS medium for human corneal storage
    • Nelson LRBA, Hodge DOMS, Bourne WMMD. In vitro comparison of Chen medium and Optisol-GS medium for human corneal storage. Cornea. 2000;19:782-787.
    • (2000) Cornea , vol.19 , pp. 782-787
    • Nelson, L.R.B.A.1    Hodge, D.O.M.S.2    Bourne, W.M.M.D.3
  • 27
    • 33747065242 scopus 로고    scopus 로고
    • Preserving the cornea: Corneal storage media
    • Jeng BH. Preserving the cornea: corneal storage media. Curr Opin Ophthalmol. 2006;17:332-337.
    • (2006) Curr Opin Ophthalmol , vol.17 , pp. 332-337
    • Jeng, B.H.1
  • 28
    • 34249022426 scopus 로고    scopus 로고
    • Photorefractive keratectomy in the cat eye: Biological and optical outcomes
    • Nagy LJ, MacRae S, Yoon G, et al. Photorefractive keratectomy in the cat eye: biological and optical outcomes. J Cataract Refract Surg. 2007;33:1051-1064.
    • (2007) J Cataract Refract Surg , vol.33 , pp. 1051-1064
    • Nagy, L.J.1    McRae, S.2    Yoon, G.3
  • 29
    • 59449088488 scopus 로고    scopus 로고
    • Optical effects of anti-TGFβ treatment after photorefractive keratectomy in a cat model
    • Buhren J, Nagy L, Swanton JN, et al. Optical effects of anti-TGFβ treatment after photorefractive keratectomy in a cat model. Invest Ophthalmol Vis Sci. 2009;50:634-643.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 634-643
    • Buhren, J.1    Nagy, L.2    Swanton, J.N.3
  • 30
    • 57849134248 scopus 로고    scopus 로고
    • Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy
    • Freudiger CW, Min W, Saar BG, et al. Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy. Science. 2008;322:1857-1861.
    • (2008) Science , vol.322 , pp. 1857-1861
    • Freudiger, C.W.1    Min, W.2    Saar, B.G.3
  • 32
    • 36949087850 scopus 로고
    • Average extinction coefficient for reabsorption of fluorescence radiation through uranin solution
    • Rohatgi KK, Singhal GS. Average extinction coefficient for reabsorption of fluorescence radiation through uranin solution. Nature. 1961;191:799-800.
    • (1961) Nature , vol.191 , pp. 799-800
    • Rohatgi, K.K.1    Singhal, G.S.2
  • 33
    • 0029273602 scopus 로고
    • Two-photon excitation 4Pi confocal microscope: Enhanced axial resolution microscope for biological research
    • Hanninen PE, Hell SW, Salo J, Soini E, Cremer C. Two-photon excitation 4Pi confocal microscope: enhanced axial resolution microscope for biological research. Appl Physics Lett. 1995;66:1698-1700.
    • (1995) Appl Physics Lett , vol.66 , pp. 1698-1700
    • Hanninen, P.E.1    Hell, S.W.2    Salo, J.3    Soini, E.4    Cremer, C.5
  • 34
    • 0031871529 scopus 로고    scopus 로고
    • Ultrathin fluorescent layers for monitoring the axial resolution in confocal and two-photon fluorescence microscopy
    • Schrader M, Hofmann UG, Hell SW. Ultrathin fluorescent layers for monitoring the axial resolution in confocal and two-photon fluorescence microscopy. J Microsc. 1998;191:135-140.
    • (1998) J Microsc , vol.191 , pp. 135-140
    • Schrader, M.1    Hofmann, U.G.2    Hell, S.W.3
  • 35
    • 0012624482 scopus 로고
    • Fluorescence of solutions: A review
    • Williams RT, Bridges JW. Fluorescence of solutions: a review. J Clin Pathol. 1964;17:371-394.
    • (1964) J Clin Pathol , vol.17 , pp. 371-394
    • Williams, R.T.1    Bridges, J.W.2
  • 36
    • 0024039744 scopus 로고
    • Mechanism of fluorescence concentration quenching of carboxyfluorescein in liposomes: Energy transfer to nonfluorescent dimers
    • Chen RF, Knutson JR. Mechanism of fluorescence concentration quenching of carboxyfluorescein in liposomes: energy transfer to nonfluorescent dimers. Anal Biochem. 1988;172:61-77.
    • (1988) Anal Biochem , vol.172 , pp. 61-77
    • Chen, R.F.1    Knutson, J.R.2
  • 37
    • 0027503192 scopus 로고
    • Aberration in confocal fluorescence microscopy induced by mismatches in refractiveindex
    • Hell S, Reiner G, Cremer C, Stelzer EHK. Aberration in confocal fluorescence microscopy induced by mismatches in refractiveindex. J Microsc. 1993;169:391-405.
    • (1993) J Microsc , vol.169 , pp. 391-405
    • Hell, S.1    Reiner, G.2    Cremer, C.3    Stelzer, E.H.K.4
  • 38
    • 0028590110 scopus 로고
    • Refractive-index-induced aberration in 2-photon confocal fluorescence microscopy
    • Jacobsen H, Hanninen P, Soini E, Hell SW. Refractive-index-induced aberration in 2-photon confocal fluorescence microscopy. J Microsc. 1994;176:226-230.
    • (1994) J Microsc , vol.176 , pp. 226-230
    • Jacobsen, H.1    Hanninen, P.2    Soini, E.3    Hell, S.W.4
  • 39
    • 67650787319 scopus 로고    scopus 로고
    • H-type dimer formation of fluorophores: A mechanism for activatable, in vivo optical molecular imaging
    • Ogawa M, Kosaka N, Choyke PL, Kobayashi H. H-type dimer formation of fluorophores: a mechanism for activatable, in vivo optical molecular imaging. ACS Chem Biol. 2009;4:535-546.
    • (2009) ACS Chem Biol , vol.4 , pp. 535-546
    • Ogawa, M.1    Kosaka, N.2    Choyke, P.L.3    Kobayashi, H.4
  • 40
    • 33746740587 scopus 로고    scopus 로고
    • Damage thresholds for exposure to NIR and blue lasers in an in vitro RPE cell system
    • Denton ML, Foltz MS, Estlack LE, et al. Damage thresholds for exposure to NIR and blue lasers in an in vitro RPE cell system. Invest Ophthalmol Vis Sci. 2006;47:3065-3073.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 3065-3073
    • Denton, M.L.1    Foltz, M.S.2    Estlack, L.E.3
  • 41
    • 33747035544 scopus 로고    scopus 로고
    • Corneal multiphoton microscopy and intratissue optical nanosurgery by nanojoule femtosecond nearinfrared pulsed lasers
    • Wang BG, Halbhuber KJ. Corneal multiphoton microscopy and intratissue optical nanosurgery by nanojoule femtosecond nearinfrared pulsed lasers. Ann Anat. 2006;188:395-409.
    • (2006) Ann Anat , vol.188 , pp. 395-409
    • Wang, B.G.1    Halbhuber, K.J.2
  • 42
    • 77954957294 scopus 로고    scopus 로고
    • In vivo non-linear optical (NLO) imaging in live rabbit eyes using the Heidelberg two-photon laser ophthalmoscope
    • Hao M, Flynn K, Nien-Shy C, et al. In vivo non-linear optical (NLO) imaging in live rabbit eyes using the Heidelberg two-photon laser ophthalmoscope. Exp Eye Res. 2010;91:308-314.
    • (2010) Exp Eye Res , vol.91 , pp. 308-314
    • Hao, M.1    Flynn, K.2    Nien-Shy, C.3
  • 43
    • 33751250148 scopus 로고    scopus 로고
    • Examination of the restoration of epithelial barrier function following superficial keratectomy
    • Hutcheon AEK, Sippel KC, Zieske JD. Examination of the restoration of epithelial barrier function following superficial keratectomy. Exp Eye Res. 2007;84:32-38.
    • (2007) Exp Eye Res , vol.84 , pp. 32-38
    • Hutcheon, A.E.K.1    Sippel, K.C.2    Zieske, J.D.3
  • 44
    • 0032921817 scopus 로고    scopus 로고
    • Fluorophotometric assessment of rabbit corneal epithelial barrier function after rigid contact lens wear
    • Ichijima H, Yokoi N, Nishizawa A, Kinoshita S. Fluorophotometric assessment of rabbit corneal epithelial barrier function after rigid contact lens wear. Cornea. 1999;18:87-91.
    • (1999) Cornea , vol.18 , pp. 87-91
    • Ichijima, H.1    Yokoi, N.2    Nishizawa, A.3    Kinoshita, S.4
  • 45
    • 21244463545 scopus 로고    scopus 로고
    • Wound healing in the cornea: A review of refractive surgery complications and new prospects for therapy
    • Netto MV, Mohan RR, Ambrosio RJ, Hutcheon AEK, Zieske JD, Wilson SE. Wound healing in the cornea: a review of refractive surgery complications and new prospects for therapy. Cornea. 2005;24:509-522.
    • (2005) Cornea , vol.24 , pp. 509-522
    • Netto, M.V.1    Mohan, R.R.2    Ambrosio, R.J.3    Hutcheon, A.E.K.4    Zieske, J.D.5    Wilson, S.E.6
  • 46
    • 0037405409 scopus 로고    scopus 로고
    • Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus
    • Gregor W, Eberhard S, Theo S. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol. 2003;135:620-627.
    • (2003) Am J Ophthalmol , vol.135 , pp. 620-627
    • Gregor, W.1    Eberhard, S.2    Theo, S.3
  • 47
    • 72149090152 scopus 로고    scopus 로고
    • Significance of the riboflavin film in corneal collagen crosslinking
    • Wollensak G, Aurich H, Wirbelauer C, Sel S. Significance of the riboflavin film in corneal collagen crosslinking. J Cataract Refract Surg. 2010;36:114-120.
    • (2010) J Cataract Refract Surg , vol.36 , pp. 114-120
    • Wollensak, G.1    Aurich, H.2    Wirbelauer, C.3    Sel, S.4
  • 48
    • 3242726883 scopus 로고    scopus 로고
    • Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy
    • Sandoval RM, Kennedy MD, Low PS, Molitoris BA. Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy. Am J Physiol Cell Physiol. 2004;287:C517-C526.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Sandoval, R.M.1    Kennedy, M.D.2    Low, P.S.3    Molitoris, B.A.4
  • 49
    • 0001703536 scopus 로고    scopus 로고
    • Synthesis and photophysical properties of new conjugated fluorophores designed for two-photon-excited fluorescence
    • Mongin O, Porres L, Moreaux L, Mertz J, Blanchard-Desce M. Synthesis and photophysical properties of new conjugated fluorophores designed for two-photon-excited fluorescence. Organic Lett. 2002;4:719-722.
    • (2002) Organic Lett , vol.4 , pp. 719-722
    • Mongin, O.1    Porres, L.2    Moreaux, L.3    Mertz, J.4    Blanchard-Desce, M.5
  • 50
    • 33744727681 scopus 로고    scopus 로고
    • The balance between corneal transparency and edema: The Proctor lecture
    • Edelhauser HF. The balance between corneal transparency and edema: the Proctor lecture. Invest Ophthalmol Vis Sci. 2006;47:1755-1767.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 1755-1767
    • Edelhauser, H.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.