Chemotherapy followed by surgery versus surgery alone in patients with resectable oesophageal squamous cell carcinoma: Long-term results of a randomized controlled trial

BMC Cancer

Volumn 11, Issue , 2011, Pages

  Boonstra, Jurjen J ^a,b   Kok, Tjebbe C ^c   Wijnhoven, Bas P L ^b   van Heijl, Mark ^d   van Berge Henegouwen, Mark I ^d   ten Kate, Fiebo J W ^e   Siersema, Peter D ^e   Dinjens, Winand N M ^a   van Lanschot, Jan J B ^b   Tilanus, Hugo W ^b   van der Gaast, Ate ^a  

^a JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c Maasstad Hospital   (Netherlands)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; ETOPOSIDE; SEROTONIN 3 ANTAGONIST; ANTINEOPLASTIC AGENT;

ADULT; ALOPECIA; ARTICLE; BLOOD TOXICITY; CANCER COMBINATION CHEMOTHERAPY; CANCER MORTALITY; CANCER RELAPSE; CANCER SURGERY; CANCER SURVIVAL; CHEMOTHERAPY INDUCED EMESIS; CONTROLLED STUDY; DISEASE FREE SURVIVAL; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; ESOPHAGUS SURGERY; FEMALE; HUMAN; INTENTION TO TREAT ANALYSIS; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PREOPERATIVE CARE; RANDOMIZED CONTROLLED TRIAL; SURVIVAL TIME; TREATMENT FAILURE; TREATMENT RESPONSE; AGED; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; ESOPHAGUS TUMOR; MIDDLE AGED; MORTALITY; MULTIMODALITY CANCER THERAPY; SQUAMOUS CELL CARCINOMA; SURVIVAL; TREATMENT OUTCOME;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CISPLATIN; COMBINED MODALITY THERAPY; ESOPHAGEAL NEOPLASMS; ETOPOSIDE; FEMALE; HUMANS; MALE; MIDDLE AGED; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 79956019775     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-181     Document Type: Article

References (15)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin 2009, 59(4):225-249. 10.3322/caac.20006, 19474385.
2. Umar SB, Fleischer DE. Esophageal cancer: epidemiology, pathogenesis and prevention. Nat Clin Pract Gastroenterol Hepatol 2008, 5(9):517-526. 10.1038/ncpgasthep1223, 18679388.
3. Weinberg RA. Leaving home early: reexamination of the canonical models of tumour progression. Cancer Cell 2008, 14(4):283-284. 10.1016/j.ccr.2008.09.009, 18835030.
4. Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003, 3(6):453-458. 10.1038/nrc1098, 12778135.
5. WHO World Health Organization handbook for reporting results of cancer treatment (publication no. 48). Geneva: WHO 1979, WHO.
6. Hermanek P, Sobin LH. TNM classification of malignant tumours. Berlin: Springer 1987, 40-2.
7. Sposto R, Stablein D, Carter-Campbell S. A partially grouped logrank test. Stat Med 1997, 16(6):695-704. 10.1002/(SICI)1097-0258(19970330)16:6<695::AID-SIM436>3.0.CO;2-C, 9131757.
8. Kok TC, Van der Gaast A, Dees J, Eykenboom WM, Van Overhagen H, Stoter G, Tilanus HW, Splinter TA. Cisplatin and etoposide in esophageal cancer: a phase II study. Rotterdam Oesophageal Tumour Study Group. Br J Cancer 1996, 74(6):980-984. 10.1038/bjc.1996.469, 2074745, 8826870.
9. Kok TC, van Lanschot JJB, Siersema PD, van Overhagen HV, Tilanus HW. Neoadjuvant chemotherapy in operable esophageal squamous cell cancer: final report of a phase III multicenter randomized controlled trial. Proc Am Soc Clin Oncol 1997, 17:984.
10. Kelsen DP, Ginsberg R, Pajak TF, Sheahan DG, Gunderson L, Mortimer J, Estes N, Haller DG, Ajani J, Kocha W, Minsky BD, Roth JA. Chemotherapy followed by surgery compared with surgery alone for localized esophageal cancer. N Engl J Med 1998, 339(27):1979-1984. 10.1056/NEJM199812313392704, 9869669.
11. Medical Research Council Esophageal Cancer Working Party Surgical resection with or without preoperative chemotherapy in esophageal cancer: a randomized controlled trial. Lancet 2002, 359(9319):1727-1733. Medical Research Council Esophageal Cancer Working Party.
12. Allum WH, Stenning SP, Bancewicz J, Clark PI, Langley RE. Long-term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer. J Clin Oncol 2009, 27(30):5062-5067. 10.1200/JCO.2009.22.2083, 19770374.
13. Kelsen DP, Winter KA, Gunderson LL, Mortimer J, Estes NC, Haller DG, Ajani JA, Kocha W, Minsky BD, Roth JA, Willett CG. Long-term results of RTOG trial 8911 (USA Intergroup 113): a random assignment trial comparison of chemotherapy followed by surgery compared with surgery alone for esophageal cancer. J Clin Oncol 2007, 25(24):3719-3725. 10.1200/JCO.2006.10.4760, 17704421.
14. Splinter T, Kok T, Kho S, Lameris H, ten Kate F, Dalesio O, Dolman B, Palmen F, Bouvy J, Burghouts J. A multicenter phase II trial of cisplatin and oral etoposide (VP-16) in inoperable non-small-cell lung cancer. Semin Oncol 1986, 13(3 Suppl 3):97-103.
15. Hulscher JB, van Sandick JW, de Boer AG, Wijnhoven BP, Tijssen JG, Fockens P, Stalmeier PF, ten Kate FJ, van Dekken H, Obertop H, Tilanus HW, van Lanschot JJB. Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus. N Engl J Med 2002, 347(21):1662-1669. 10.1056/NEJMoa022343, 12444180.