Chimerism levels after stem cell transplantation are primarily determined by the ratio of donor to host stem cells

Blood

Volumn 117, Issue 16, 2011, Pages 4400-4401

  Westerhuis, Geert ^a   Van Pel, Melissa ^a   Toes, René E M ^a   Staal, Frank J T ^a   Fibbe, Willem E ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ABLATION THERAPY; ANIMAL CELL; BONE MARROW; CELL POPULATION; CHIMERA; DONOR; GENE MUTATION; GENOTYPE; GRANULOCYTE; HEMATOPOIETIC STEM CELL; HOST CELL; LETTER; NONHUMAN; PRIORITY JOURNAL;

EID: 79955980429     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-01-328518     Document Type: Letter

References (5)

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2. Bhattacharya D, Czechowicz A, Ooi AG, Rossi DJ, Bryder D, Weissman IL. Niche recycling through division-independent egress of hematopoietic stem cells. J Exp Med. 2009;206(12):2837-2850.
3. Benveniste P, Cantin C, Hyam D, Iscove NN. Hematopoietic stem cells engraft in mice with absolute efficiency. Nat Immunol. 2003;4(7):708-713. (Pubitemid 36874449)
4. Westerhuis G, Maas WG, Toes RE, Fibbe WE. Persisting NK cell alloreactivity in the presence of long-term stable hematopoietic chimerism. Exp Hematol. 2009;37(6):739-743.
5. Westerhuis G, Maas WG, Willemze R, Toes RE, Fibbe WE. Long-term mixed chimerism after immunologic conditioning and MHC-mismatched stem-cell transplantation is dependent on NK-cell tolerance. Blood. 2005;106(6):2215-2220. (Pubitemid 41291743)