Characteristics and outcomes of Fusobacterium nucleatum bacteremia-a 6-year experience at a tertiary care hospital in northern Taiwan

Diagnostic Microbiology and Infectious Disease

Volumn 70, Issue 2, 2011, Pages 167-174

  Yang, Chien Chang ^a   Ye, Jung Jr ^a   Hsu, Po Chang ^a   Chang, Hong Jyun ^a   Cheng, Chun Wen ^a   Leu, Hsieh Shong ^a   Chiang, Ping Cherng ^a   Lee, Ming Hsun ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Bacteremia; Fusobacterium nucleatum; Mortality; Nosocomial; Pneumonia

Indexed keywords

PENICILLIN G; PIPERACILLIN; SULTAMICILLIN;

ABDOMINAL INFECTION; ADULT; ANEMIA; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTEREMIA; COMORBIDITY; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DISEASE SEVERITY; FEMALE; FUSOBACTERIUM NUCLEATUM; FUSOBACTERIUM NUCLEATUM BACTEREMIA; HOSPITAL INFECTION; HOSPITAL PATIENT; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MORTALITY; NONHUMAN; OROPHARYNX CANCER; PNEUMONIA; PRIORITY JOURNAL; RESPIRATORY FAILURE; RETROSPECTIVE STUDY; SCORING SYSTEM; TAIWAN; TERTIARY HEALTH CARE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTEREMIA; COMORBIDITY; FEMALE; FUSOBACTERIUM INFECTIONS; FUSOBACTERIUM NUCLEATUM; HOSPITALS; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; PROGNOSIS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TAIWAN; TREATMENT OUTCOME; YOUNG ADULT;

EID: 79955970343     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2010.12.017     Document Type: Article

References (28)

1. Appelbaum P.C., Spangler S.K., Jacobs M.R. Beta-lactamase production and susceptibilities to amoxicillin, amoxicillin-clavulanate, ticarcillin, ticarcillin-clavulanate, cefoxitin, imipenem, and metronidazole of 320 non-Bacteroides fragilis Bacteroides isolates and 129 fusobacteria from 28 U.S. centers. Antimicrob. Agents Chemother. 1990, 34:1546-1550.
2. Bartlett J.G. Anaerobic bacterial infections of the lung. Chest 1987, 91:901-909.
3. Bennett K.W., Eley A. Fusobacteria: new taxonomy and related diseases. J. Med. Microbiol. 1993, 39:246-254.
4. Bolstad A.I., Jensen H.B., Bakken V. Taxonomy, biology, and periodontal aspects of Fusobacterium nucleatum. Clin. Microbiol. Rev. 1996, 9:55-71.
5. Bourgault A.M., Lamothe F., Dolce P., Saint-Jean L., Saint-Antoine P. Fusobacterium bacteremia: clinical experience with 40 cases. Clin. Infect. Dis. 1997, 25(Suppl 2):181-183.
6. Brook I. Fusobacterial infections in children. J. Infect. 1994, 28:155-165.
7. Brook I. The role of anaerobic bacteria in bacteremia. Anaerobe 2010, 16:183-189.
8. Chaim W., Mazor M. Intraamniotic infection with fusobacteria. Arch. Gynecol. Obstet. 1992, 251:1-7.
9. Chan Y., Chan C.H. Antibiotic resistance of pathogenic bacteria from odontogenic infections in Taiwan. J. Microbiol. Immunol. Infect. 2003, 36:105-110.
10. Cheong H.S., Kang C.I., Wi Y.M., Kim E.S., Lee J.S., Ko K.S., Chung D.R., Lee N.Y., Song J.H., Peck K.R. Clinical significance and predictors of community-onset Pseudomonas aeruginosa bacteremia. Am. J. Med. 2008, 121:709-714.
11. Clinical and Laboratory Standards Institute (CLSI) Methods for antimicrobial susceptibility Testing of anaerobic bacteria; approved standard-seventh edition. Document M11-A7 2007, CLSI, Wayne, PA.
12. Falkler W.A., Montgomery J., Nauman R.K., Alpers M. Isolation of Fusobacterium nucleatum and electron microscopic observations of spirochetes from tropical skin ulcers in Papua New Guinea. Am. J. Trop. Med. Hyg 1989, 40:390-398.
13. Gonzalez-Gay M.A., Sanchez-Andrade A., Cereijo M.J., Pulpeiro J.R., Armesto V. Pyomyositis and septic arthritis from Fusobacterium nucleatum in a nonimmunocompromised adult. J. Rheumatol. 1993, 20:518-520.
14. Henry S., DeMaria A., McCabe W.R. Bacteremia due to Fusobacterium species. Am. J. Med. 1983, 75:225-231.
15. Hill M.K., Sanders C.V. Anaerobic disease of the lung. Infect. Dis. Clin. North Am. 1991, 5:453-466.
16. Hillier S.L., Krohn M.A., Rabe L.K., Klebanoff S.J., Eschenbach D.A. The normal vaginal flora, H2O2-producing lactobacilli, and bacterial vaginosis in pregnant women. Clin. Infect. Dis. 1993, 16(Suppl 4):273-281.
17. Huggan P.J., Murdoch D.R. Fusobacterial infections: clinical spectrum and incidence of invasive disease. J. Infect. 2008, 57:283-289.
18. Johanson W.G., Harris G.D. Aspiration pneumonia, anaerobic infections, and lung abscess. Med. Clin. North Am. 1980, 64:385-394.
19. Jousimies-Somer H., Savolainen S., Makitie A., Ylikoski J. Bacteriologic findings in peritonsillar abscesses in young adults. Clin. Infect. Dis. 1993, 16(Suppl 4):292-298.
20. Kononen E., Kanervo A., Salminen K., Jousimies-Somer H. beta-lactamase production and antimicrobial susceptibility of oral heterogeneous Fusobacterium nucleatum populations in young children. Antimicrob. Agents Chemother. 1999, 43:1270-1273.
21. Liu C.Y., Huang Y.T., Liao C.H., Yen L.C., Lin H.Y., Hsueh P.R. Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. Antimicrob. Agents Chemother. 2008, 52:3161-3168.
22. Moore W.E., Moore L.V. The bacteria of periodontal diseases. Periodontol. 2000 1994, 5:66-77.
23. Rhee J.Y., Kwon K.T., Ki H.K., Shin S.Y., Jung D.S., Chung D.R., Ha B.C., Peck K.R., Song J.H. Scoring systems for prediction of mortality in patients with intensive care unit-acquired sepsis: a comparison of the Pitt bacteremia score and the Acute Physiology and Chronic Health Evaluation II scoring systems. Shock 2009, 31:146-150.
24. Ribot S., Gal K., Goldblat M.V., Eslami H.H. The role of anaerobic bacteria in the pathogenesis of urinary tract infections. J. Urol. 1981, 126:852-853.
25. Scoular A., Corcoran G.D., Malin A., Evans B.A., Davies A., Miller R.F. Fusobacterium nucleatum bacteraemia with multiple liver abscesses in an HIV-I antibody positive man with IgG2 deficiency. J. Infect. 1992, 24:321-325.
26. Shammas N.W., Murphy G.W., Eichelberger J., Klee D., Schwartz R., Bachman W. Infective endocarditis due to Fusobacterium nucleatum: case report and review of the literature. Clin. Cardiol. 1993, 16:72-75.
27. Su C.P., Huang P.Y., Yang C.C., Lee M.H. Fusobacterium bacteremia: clinical significance and outcomes. J. Microbiol. Immunol. Infect. 2009, 42:336-342.
28. Weber G., Borer A., Riesenberg K., Schlaeffer F. Infective endocarditis due to Fusobacterium nucleatum in an intravenous drug abuser. Eur. J. Clin. Microbiol. Infect. Dis. 1999, 18:655-657.