-
1
-
-
12844276589
-
Lipocalins in drug discovery: from natural ligand-binding proteins to "anticalins"
-
Schlehuber S, Skerra A. Lipocalins in drug discovery: from natural ligand-binding proteins to "anticalins". Drug Discov Today 2005; 10: 23-33.
-
(2005)
Drug Discov Today
, vol.10
, pp. 23-33
-
-
Schlehuber, S.1
Skerra, A.2
-
2
-
-
0027525156
-
Dominant expression of mRNA for prostaglandin D synthase in leptomeninges, choroid plexus, and oligodendrocytes of the adult rat brain
-
Urade Y, Kitahama K, Ohishi H, Kaneko T, Mizuno N, Hayaishi O. Dominant expression of mRNA for prostaglandin D synthase in leptomeninges, choroid plexus, and oligodendrocytes of the adult rat brain. Proc Natl Acad Sci USA 1993; 90: 9070-9074.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 9070-9074
-
-
Urade, Y.1
Kitahama, K.2
Ohishi, H.3
Kaneko, T.4
Mizuno, N.5
Hayaishi, O.6
-
3
-
-
0037731753
-
Hematopoietic prostaglandin D synthase is expressed in microglia in the developing postnatal mouse brain
-
Mohri I, Eguchi N, Suzuki K, Urade Y, Taniike M. Hematopoietic prostaglandin D synthase is expressed in microglia in the developing postnatal mouse brain. Glia 2003; 42: 263-274.
-
(2003)
Glia
, vol.42
, pp. 263-274
-
-
Mohri, I.1
Eguchi, N.2
Suzuki, K.3
Urade, Y.4
Taniike, M.5
-
4
-
-
0027974137
-
Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene
-
Hirata M, Kakizuka A, Aizawa M, Ushikubi F, Narumiya S. Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene. Proc Natl Acad Sci USA 1994; 91: 11192-11196.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11192-11196
-
-
Hirata, M.1
Kakizuka, A.2
Aizawa, M.3
Ushikubi, F.4
Narumiya, S.5
-
5
-
-
0035862329
-
Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2
-
Hirai H, Tanaka K, Yoshie O, Ogawa K, Kenmotsu K, Takamori Y, Ichimasa M, Sugamura K, Nakamura M, Takano S, Nagata K. Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. J Exp Med 2001; 193: 255-261.
-
(2001)
J Exp Med
, vol.193
, pp. 255-261
-
-
Hirai, H.1
Tanaka, K.2
Yoshie, O.3
Ogawa, K.4
Kenmotsu, K.5
Takamori, Y.6
Ichimasa, M.7
Sugamura, K.8
Nakamura, M.9
Takano, S.10
Nagata, K.11
-
6
-
-
0036007458
-
Prostaglandin D2 in sleep-wake regulation: recent progress and perspectives
-
Hayaishi O, Urade Y. Prostaglandin D2 in sleep-wake regulation: recent progress and perspectives. Neuroscientist 2002; 8: 12-15.
-
(2002)
Neuroscientist
, vol.8
, pp. 12-15
-
-
Hayaishi, O.1
Urade, Y.2
-
7
-
-
13044249874
-
Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice
-
Eguchi N, Minami T, Shirafuji N, Kanaoka Y, Tanaka T, Nagata A, Yoshida N, Urade Y, Ito S, Hayaishi O. Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice. Proc Natl Acad Sci USA 1999; 96: 726-730.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 726-730
-
-
Eguchi, N.1
Minami, T.2
Shirafuji, N.3
Kanaoka, Y.4
Tanaka, T.5
Nagata, A.6
Yoshida, N.7
Urade, Y.8
Ito, S.9
Hayaishi, O.10
-
8
-
-
0020199993
-
Role of prostaglandin D2 in the hypothermia of rats caused by bacterial lipopolysaccharide
-
Ueno R, Narumiya S, Ogorochi T, Nakayama T, Ishikawa Y, Hayaishi O. Role of prostaglandin D2 in the hypothermia of rats caused by bacterial lipopolysaccharide. Proc Natl Acad Sci USA 1982; 79: 6093-6097.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 6093-6097
-
-
Ueno, R.1
Narumiya, S.2
Ogorochi, T.3
Nakayama, T.4
Ishikawa, Y.5
Hayaishi, O.6
-
9
-
-
39649105875
-
Central prostaglandin D(2) stimulates food intake via the neuropeptide Y system in mice
-
Ohinata K, Takagi K, Biyajima K, Fujiwara Y, Fukumoto S, Eguchi N, Urade Y, Asakawa A, Fujimiya M, Inui A, Yoshikawa M. Central prostaglandin D(2) stimulates food intake via the neuropeptide Y system in mice. FEBS Lett 2008; 582: 679-684.
-
(2008)
FEBS Lett
, vol.582
, pp. 679-684
-
-
Ohinata, K.1
Takagi, K.2
Biyajima, K.3
Fujiwara, Y.4
Fukumoto, S.5
Eguchi, N.6
Urade, Y.7
Asakawa, A.8
Fujimiya, M.9
Inui, A.10
Yoshikawa, M.11
-
10
-
-
77749316918
-
Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo
-
Fujitani Y, Aritake K, Kanaoka Y, Goto T, Takahashi N, Fujimori K, Kawada T. Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo. FEBS J 2010; 277: 1410-1419.
-
(2010)
FEBS J
, vol.277
, pp. 1410-1419
-
-
Fujitani, Y.1
Aritake, K.2
Kanaoka, Y.3
Goto, T.4
Takahashi, N.5
Fujimori, K.6
Kawada, T.7
-
11
-
-
57849159302
-
Knockout of the l-pgds gene aggravates obesity and atherosclerosis in mice
-
Tanaka R, Miwa Y, Mou K, Tomikawa M, Eguchi N, Urade Y, Takahashi-Yanaga F, Morimoto S, Wake N, Sasaguri T. Knockout of the l-pgds gene aggravates obesity and atherosclerosis in mice. Biochem Biophys Res Commun 2009; 378: 851-856.
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 851-856
-
-
Tanaka, R.1
Miwa, Y.2
Mou, K.3
Tomikawa, M.4
Eguchi, N.5
Urade, Y.6
Takahashi-Yanaga, F.7
Morimoto, S.8
Wake, N.9
Sasaguri, T.10
-
12
-
-
27744596187
-
Effect of three treatment schedules of recombinant methionyl human leptin on body weight in obese adults: a randomized, placebo-controlled trial
-
Zelissen PM, Stenlof K, Lean ME, Fogteloo J, Keulen ET, Wilding J, Finer N, Rossner S, Lawrence E, Fletcher C, McCamish M. Effect of three treatment schedules of recombinant methionyl human leptin on body weight in obese adults: a randomized, placebo-controlled trial. Diabetes Obes Metab 2005; 7: 755-761.
-
(2005)
Diabetes Obes Metab
, vol.7
, pp. 755-761
-
-
Zelissen, P.M.1
Stenlof, K.2
Lean, M.E.3
Fogteloo, J.4
Keulen, E.T.5
Wilding, J.6
Finer, N.7
Rossner, S.8
Lawrence, E.9
Fletcher, C.10
McCamish, M.11
-
13
-
-
0141675985
-
Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese subjects
-
Stenlof K, Wernstedt I, Fjallman T, Wallenius V, Wallenius K, Jansson JO. Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese subjects. J Clin Endocrinol Metab 2003; 88: 4379-4383.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 4379-4383
-
-
Stenlof, K.1
Wernstedt, I.2
Fjallman, T.3
Wallenius, V.4
Wallenius, K.5
Jansson, J.O.6
-
14
-
-
0028257939
-
A multicompartment body composition technique based on computerized tomography
-
Chowdhury B, Sjostrom L, Alpsten M, Kostanty J, Kvist H, Lofgren R. A multicompartment body composition technique based on computerized tomography. Int J Obes Relat Metab Disord 1994; 18: 219-234.
-
(1994)
Int J Obes Relat Metab Disord
, vol.18
, pp. 219-234
-
-
Chowdhury, B.1
Sjostrom, L.2
Alpsten, M.3
Kostanty, J.4
Kvist, H.5
Lofgren, R.6
-
15
-
-
34547383713
-
Preparation of iodine-131 labelled human growth hormone of high specific activity
-
Hunter WM, Greenwood FC. Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature 1962; 194: 495-496.
-
(1962)
Nature
, vol.194
, pp. 495-496
-
-
Hunter, W.M.1
Greenwood, F.C.2
-
16
-
-
0027156728
-
Biosynthesis of corticotropin-releasing hormone in human T-lymphocytes
-
Ekman R, Servenius B, Castro MG, Lowry PJ, Cederlund AS, Bergman O, Sjogren HO. Biosynthesis of corticotropin-releasing hormone in human T-lymphocytes. J Neuroimmunol 1993; 44: 7-13.
-
(1993)
J Neuroimmunol
, vol.44
, pp. 7-13
-
-
Ekman, R.1
Servenius, B.2
Castro, M.G.3
Lowry, P.J.4
Cederlund, A.S.5
Bergman, O.6
Sjogren, H.O.7
-
17
-
-
0029065132
-
Chronic parenteral antidepressant treatment in rats: unaltered levels and processing of neuropeptide Y (NPY) and corticotropin-releasing hormone (CRH)
-
Heilig M, Ekman R. Chronic parenteral antidepressant treatment in rats: unaltered levels and processing of neuropeptide Y (NPY) and corticotropin-releasing hormone (CRH). Neurochem Int 1995; 26: 351-355.
-
(1995)
Neurochem Int
, vol.26
, pp. 351-355
-
-
Heilig, M.1
Ekman, R.2
-
18
-
-
0020352288
-
Characterization and application of a radioimmunoassay for beta-endorphin using an antiserum with negligible cross-reactivity against beta-lipotropin
-
Bramnert M, Ekman R, Larsson I, Thorell JI. Characterization and application of a radioimmunoassay for beta-endorphin using an antiserum with negligible cross-reactivity against beta-lipotropin. Regul Pept 1982; 5: 65-75.
-
(1982)
Regul Pept
, vol.5
, pp. 65-75
-
-
Bramnert, M.1
Ekman, R.2
Larsson, I.3
Thorell, J.I.4
-
19
-
-
0022902650
-
Beta-endorphin-immunoreactive components in human cerebrospinal fluid
-
Winther Bach F, Ekman R, Jensen FM. Beta-endorphin-immunoreactive components in human cerebrospinal fluid. Regul Pept 1986; 4: 189-198.
-
(1986)
Regul Pept
, vol.4
, pp. 189-198
-
-
Winther Bach, F.1
Ekman, R.2
Jensen, F.M.3
-
20
-
-
0024314976
-
Neuropeptides in the human appendix. Distribution and motor effects
-
Ekblad E, Arnbjornsson E, Ekman R, Hakanson R, Sundler F. Neuropeptides in the human appendix. Distribution and motor effects. Dig Dis Sci 1989; 34: 1217-1230.
-
(1989)
Dig Dis Sci
, vol.34
, pp. 1217-1230
-
-
Ekblad, E.1
Arnbjornsson, E.2
Ekman, R.3
Hakanson, R.4
Sundler, F.5
-
21
-
-
67651172791
-
Similar metabolic responses to calorie restriction in lean and obese Zucker rats
-
Chiba T, Komatsu T, Nakayama M, Adachi T, Tamashiro Y, Hayashi H, Yamaza H, Higami Y, Shimokawa I. Similar metabolic responses to calorie restriction in lean and obese Zucker rats. Mol Cell Endocrinol 2009; 309: 17-25.
-
(2009)
Mol Cell Endocrinol
, vol.309
, pp. 17-25
-
-
Chiba, T.1
Komatsu, T.2
Nakayama, M.3
Adachi, T.4
Tamashiro, Y.5
Hayashi, H.6
Yamaza, H.7
Higami, Y.8
Shimokawa, I.9
-
22
-
-
60849087959
-
Central and peripheral effects of chronic food restriction and weight restoration in the rat
-
Kinzig KP, Hargrave SL, Tao EE. Central and peripheral effects of chronic food restriction and weight restoration in the rat. Am J Physiol Endocrinol Metab 2009; 296: E282-E290.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Kinzig, K.P.1
Hargrave, S.L.2
Tao, E.E.3
-
23
-
-
68049102072
-
Prostaglandin D2 produced by hematopoietic prostaglandin D synthase contributes to LPS-induced fever
-
Gao W, Schmidtko A, Wobst I, Lu R, Angioni C, Geisslinger G. Prostaglandin D2 produced by hematopoietic prostaglandin D synthase contributes to LPS-induced fever. J Physiol Pharmacol 2009; 60: 145-150.
-
(2009)
J Physiol Pharmacol
, vol.60
, pp. 145-150
-
-
Gao, W.1
Schmidtko, A.2
Wobst, I.3
Lu, R.4
Angioni, C.5
Geisslinger, G.6
-
24
-
-
72049093475
-
Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome
-
Poritsanos NJ, Mizuno TM, Lautatzis ME, Vrontakis M. Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome. Int J Obes (Lond) 2009; 33: 1381-1389.
-
(2009)
Int J Obes (Lond)
, vol.33
, pp. 1381-1389
-
-
Poritsanos, N.J.1
Mizuno, T.M.2
Lautatzis, M.E.3
Vrontakis, M.4
-
25
-
-
45849151307
-
Galanin, galanin receptors and drug targets
-
Mitsukawa K, Lu X, Bartfai T. Galanin, galanin receptors and drug targets. Cell Mol Life Sci 2008; 65: 1796-1805.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1796-1805
-
-
Mitsukawa, K.1
Lu, X.2
Bartfai, T.3
-
26
-
-
38549170090
-
Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference
-
Adams AC, Clapham JC, Wynick D, Speakman JR. Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference. J Neuroendocrinol 2008; 20: 199-206.
-
(2008)
J Neuroendocrinol
, vol.20
, pp. 199-206
-
-
Adams, A.C.1
Clapham, J.C.2
Wynick, D.3
Speakman, J.R.4
-
27
-
-
68549139946
-
Clinical review: the pathogenetic role of cortisol in the metabolic syndrome: a hypothesis
-
Anagnostis P, Athyros VG, Tziomalos K, Karagiannis A, Mikhailidis DP. Clinical review: the pathogenetic role of cortisol in the metabolic syndrome: a hypothesis. J Clin Endocrinol Metab 2009; 94: 2692-2701.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 2692-2701
-
-
Anagnostis, P.1
Athyros, V.G.2
Tziomalos, K.3
Karagiannis, A.4
Mikhailidis, D.P.5
-
28
-
-
33845667299
-
The hypothalamic-pituitary-adrenal axis activity in obesity and the metabolic syndrome
-
Pasquali R, Vicennati V, Cacciari M, Pagotto U. The hypothalamic-pituitary-adrenal axis activity in obesity and the metabolic syndrome. Ann NY Acad Sci 2006; 1083: 111-128.
-
(2006)
Ann NY Acad Sci
, vol.1083
, pp. 111-128
-
-
Pasquali, R.1
Vicennati, V.2
Cacciari, M.3
Pagotto, U.4
-
29
-
-
0037557907
-
Dexamethasone induces lipocalin-type prostaglandin D synthase gene expression in mouse neuronal cells
-
Garcia-Fernandez LF, Iniguez MA, Eguchi N, Fresno M, Urade Y, Munoz A. Dexamethasone induces lipocalin-type prostaglandin D synthase gene expression in mouse neuronal cells. J Neurochem 2000; 75: 460-470.
-
(2000)
J Neurochem
, vol.75
, pp. 460-470
-
-
Garcia-Fernandez, L.F.1
Iniguez, M.A.2
Eguchi, N.3
Fresno, M.4
Urade, Y.5
Munoz, A.6
-
30
-
-
59649106564
-
Inducible prostaglandin E2 synthesis interacts in a temporally supplementary sequence with constitutive prostaglandin-synthesizing enzymes in creating the hypothalamic-pituitary-adrenal axis response to immune challenge
-
Elander L, Engstrom L, Ruud J, Mackerlova L, Jakobsson PJ, Engblom D, Nilsberth C, Blomqvist A. Inducible prostaglandin E2 synthesis interacts in a temporally supplementary sequence with constitutive prostaglandin-synthesizing enzymes in creating the hypothalamic-pituitary-adrenal axis response to immune challenge. J Neurosci 2009; 29: 1404-1413.
-
(2009)
J Neurosci
, vol.29
, pp. 1404-1413
-
-
Elander, L.1
Engstrom, L.2
Ruud, J.3
Mackerlova, L.4
Jakobsson, P.J.5
Engblom, D.6
Nilsberth, C.7
Blomqvist, A.8
-
31
-
-
49749145595
-
Central prostaglandins in food intake regulation
-
Ohinata K, Yoshikawa M. Central prostaglandins in food intake regulation. Nutrition 2008; 24: 798-801.
-
(2008)
Nutrition
, vol.24
, pp. 798-801
-
-
Ohinata, K.1
Yoshikawa, M.2
|