-
1
-
-
0028198192
-
Long term response to chemotherapy in patients with visceral metastatic melanoma
-
Coates AS, Segelov E. Long term response to chemotherapy in patients with visceral metastatic melanoma. Ann Oncol. 1994;5:249-251. (Pubitemid 24097520)
-
(1994)
Annals of Oncology
, vol.5
, Issue.3
, pp. 249-251
-
-
Coates, A.S.1
Segelov, E.2
-
2
-
-
0003077969
-
Cutaneous melanoma
-
DeVita VT Jr, Hellman S, Rosenber SA, eds., 5th ed. Philadelphia, PA: Lippincott-Raven
-
Balch CM, Reintgen DS, Kirkwood JM, et al. Cutaneous melanoma. In: DeVita VT Jr, Hellman S, Rosenber SA, eds. Cancer: Principles and Practice of Oncology. 5th ed. Philadelphia, PA: Lippincott-Raven; 1997:1947-1994.
-
(1997)
Cancer: Principles and Practice of Oncology
, pp. 1947-1994
-
-
Balch, C.M.1
Reintgen, D.S.2
Kirkwood, J.M.3
-
3
-
-
0031805725
-
Phase III trial of dacarbazine versus dacarbazine with interferon alfa-2b versus tamoxifen versus dacarbazine with interferon alfa-2b and tamoxifen in patients with metastatic malignant melanoma: An Eastern Cooperative Oncology Group study
-
Falkson CI, Ibrahim J, Kirkwood JM, et al. Phase III trial of dacarbazine versus dacarbazine with interferon alfa-2b versus tamoxifen versus dacarbazine with interferon alfa-2b and tamoxifen in patients with metastatic malignant melanoma: an Eastern Cooperative Oncology Group study. J Clin Oncol. 1998;16:1743-1751.
-
(1998)
J Clin Oncol
, vol.16
, pp. 1743-1751
-
-
Falkson, C.I.1
Ibrahim, J.2
Kirkwood, J.M.3
-
4
-
-
0033989205
-
Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
-
Middleton MR, Grob JJ, Aaronson N, et al. Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma. J Clin Oncol. 2000;18:158-166. (Pubitemid 30036349)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.1
, pp. 158-166
-
-
Middleton, M.R.1
Grob, J.J.2
Aaronson, N.3
Fierlbeck, G.4
Tilgen, W.5
Seiter, S.6
Gore, M.7
Aamdal, S.8
Cebon, J.9
Coates, A.10
Dreno, B.11
Henz, M.12
Schadendorf, D.13
Kapp, A.14
Weiss, J.15
Fraass, U.16
Statkevich, P.17
Muller, M.18
Thatcher, N.19
-
5
-
-
1842562211
-
Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: A phase III study
-
DOI 10.1200/JCO.2004.04.165
-
Avril MF, Aamdal S, Grob JJ, et al. Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study. J Clin Oncol. 2004;22:1118-1125. (Pubitemid 41095046)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.6
, pp. 1118-1125
-
-
Avril, M.F.1
Aamdal, S.2
Grob, J.J.3
Hauschild, A.4
Mohr, P.5
Bonerandi, J.J.6
Weichenthal, M.7
Neuber, K.8
Bieber, T.9
Gilde, K.10
Porta, V.G.11
Fra, J.12
Bonneterre, J.13
Saiag, P.14
Kamanabrou, D.15
Pehamberger, H.16
Sufliarsky, J.17
Larriba, J.L.G.18
Scherrer, A.19
Menu, Y.20
more..
-
6
-
-
3843113670
-
Re-evaluating the role of dacarbazine in metastatic melanoma: What have we learned in 30 years?
-
DOI 10.1016/j.ejca.2004.04.030, PII S0959804904004009
-
Eggermont AM, Kirkwood JM. Re-evaluating the role of dacarbazine in metastatic melanoma: what have we learned in 30 years? Eur J Cancer. 2004;40:1825-1836. (Pubitemid 39036756)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.12
, pp. 1825-1836
-
-
Eggermont, A.M.M.1
Kirkwood, J.M.2
-
7
-
-
0036970548
-
Docetaxel in combination with dacarbazine in patients with advanced melanoma
-
DOI 10.1159/000066225
-
Bafaloukos D, Aravantinos G, Fountzilas G, et al. Docetaxel in combination with dacarbazine in patients with advanced melanoma. Oncology. 2002;63: 333-337. (Pubitemid 36151525)
-
(2002)
Oncology
, vol.63
, Issue.4
, pp. 333-337
-
-
Bafaloukos, D.1
Aravantinos, G.2
Fountzilas, G.3
Stathopoulos, G.4
Gogas, H.5
Samonis, G.6
Briasoulis, E.7
Mylonakis, N.8
Skarlos, D.V.9
Kosmidis, P.10
-
8
-
-
0026513077
-
Phase i trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856)
-
Newlands ES, Blackledge GR, Slack JA, et al. Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856). Br J Cancer. 1992;65:287-291.
-
(1992)
Br J Cancer
, vol.65
, pp. 287-291
-
-
Newlands, E.S.1
Blackledge, G.R.2
Slack, J.A.3
-
9
-
-
0025924721
-
O6-alkylguanine-DNA alkyltrasferase depletion and regeneration in human peripheral lymphocytes following dacarbazine and fotemustine
-
Lee SM, Thatcher N, Margison GP. O6-alkylguanine-DNA alkyltrasferase depletion and regeneration in human peripheral lymphocytes following dacarbazine and fotemustine. Cancer Res. 1991;51:619-623.
-
(1991)
Cancer Res
, vol.51
, pp. 619-623
-
-
Lee, S.M.1
Thatcher, N.2
Margison, G.P.3
-
10
-
-
79955945492
-
Phase i trial of lomeguatrib (PN) combined with dacarbazine (DTIC) for treatment of patients with melanoma and other solid tumors: Initial results (2006 ASCO Annual Meeting Proceedings)
-
Abstract 8016
-
Tawbi H, Tarhini A, Moschos S, et al. Phase I trial of lomeguatrib (PN) combined with dacarbazine (DTIC) for treatment of patients with melanoma and other solid tumors: initial results (2006 ASCO Annual Meeting Proceedings). J Clin Oncol. 2006;24(suppl):18S. Abstract 8016.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Tawbi, H.1
Tarhini, A.2
Moschos, S.3
-
11
-
-
35148894301
-
First and flnal report of a phase II study of the poly-(ADP-ribosed) polymerase (PARR) inhibitor, AGO14699 in combination with temozolomide (TMZ) in patients with metastatic malignant melanoma (MM) (2006 ASCO Annual Meeting Proceedings)
-
Abstract 8013
-
Plummer R, Lorigan P, Evans J, et al. First and flnal report of a phase II study of the poly-(ADP-ribosed) polymerase (PARR) inhibitor, AGO14699 in combination with temozolomide (TMZ) in patients with metastatic malignant melanoma (MM) (2006 ASCO Annual Meeting Proceedings). J Clin Oncol. 2006;24(suppl):18S. Abstract 8013.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Plummer, R.1
Lorigan, P.2
Evans, J.3
-
12
-
-
0025878384
-
Brain metastases of malignant melanomas
-
Boaziz C, Breau JL, Morere JF, et al. Brain metastases of malignant melanomas. Bull Cancer. 1991;78:347-353.
-
(1991)
Bull Cancer
, vol.78
, pp. 347-353
-
-
Boaziz, C.1
Breau, J.L.2
Morere, J.F.3
-
13
-
-
0025109821
-
Final report of the French multicenter phase II study of the nitrosourea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastases
-
Jacquillat C, Khayat D, Banzer P, et al. Final report of the French multicentric phase II study of the nitrosurea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastases. Cancer. 1990;66:1873-1878. (Pubitemid 20385954)
-
(1990)
Cancer
, vol.66
, Issue.9
, pp. 1873-1878
-
-
Jacquillat, C.1
Khayat, D.2
Banzet, P.3
Weil, M.4
Fumoleau, P.5
Avril, M.-F.6
Namer, M.7
Bonneterre, J.8
Kerbrat, P.9
Bonerandi, J.J.10
Bugat, R.11
Montcuquet, P.12
Cupissol, D.13
Lauvin, R.14
Vilmer, C.15
Prache, C.16
Bizzari, J.P.17
-
14
-
-
0025906511
-
Multicenter phase II trial of the single fotemustine in patients with advanced malignant melanoma
-
Calabresi E, Aapro M, Becquart D, et al. Multicenter phase II trial of the single fotemustine in patients with advanced malignant melanoma. Ann Oncol. 1991;2:377-378.
-
(1991)
Ann Oncol
, vol.2
, pp. 377-378
-
-
Calabresi, E.1
Aapro, M.2
Becquart, D.3
-
15
-
-
0029066665
-
Palliative therapy of melanoma patients with fotemustine. Inverse relationship between tumor load and treatment effectiveness. A multicenter phase II trial of the EORTC-Mela-noma Cooperative Group (MCG)
-
Kleeberg UR, Engel E, Israels P, et al. Palliative therapy of melanoma patients with fotemustine. Inverse relationship between tumor load and treatment effectiveness. A multicenter phase II trial of the EORTC-Mela-noma Cooperative Group (MCG). Melanoma Res. 1995;5:195-200.
-
(1995)
Melanoma Res
, vol.5
, pp. 195-200
-
-
Kleeberg, U.R.1
Engel, E.2
Israels, P.3
-
16
-
-
0001823077
-
Systemic cytotoxic and biologic therapy mela-noma
-
DeVita VT, Hellman S, Rosenberg SA, eds., Philadelphia, PA: Lippincott
-
Kirkwood JM, Agarwala S. Systemic cytotoxic and biologic therapy mela-noma. In: DeVita VT, Hellman S, Rosenberg SA, eds. PPO Updates. Vol 7. Philadelphia, PA: Lippincott; 1993:1
-
(1993)
PPO Updates
, vol.7
, pp. 1
-
-
Kirkwood, J.M.1
Agarwala, S.2
-
17
-
-
0023258489
-
WR-2721 and high-dose cisplatin: An active combination in the treatment of metastatic melanoma
-
Glover D, Glick JH, Weiler C, et al. WR-2721 and high-dose cisplatin: an active combination in the treatment of metastatic melanoma. J Clin Oncol. 1987;5:574-578. (Pubitemid 17062494)
-
(1987)
Journal of Clinical Oncology
, vol.5
, Issue.4
, pp. 574-578
-
-
Glover, D.1
Glick, J.H.2
Weiler, C.3
-
18
-
-
1542330126
-
Phase II randomized trial of cisplatin and WR-2721 versus cisplatin alone for metastatic melanoma: An Eastern Cooperative Oncology Group Study (E1686)
-
DOI 10.1097/00008390-200312000-00012
-
Glover D, Ibrahim J, Kirkwood J, et al. Phase II randomized trial of cisplatin and WR-2721 versus cisplatin alone for metastatic melanoma: an Eastern Cooperative Oncology Group Study (E1686). Melanoma Res. 2003;13:619-626. (Pubitemid 38296900)
-
(2003)
Melanoma Research
, vol.13
, Issue.6
, pp. 619-626
-
-
Glover, D.1
Ibrahim, J.2
Kirkwood, J.3
Glick, J.4
Karp, D.5
Stewart, J.6
Ewell, M.7
Borden, E.8
-
19
-
-
0023092168
-
Phase II trial of carboplatin in advanced malignant melanoma
-
Evans LM, Casper ES, Rosenbluth R. Participating community oncology program investigators: phase II trial of carboplatin in advanced malignant melanoma. Cancer Treat Rep. 1987;71:171-172. (Pubitemid 17030148)
-
(1987)
Cancer Treatment Reports
, vol.71
, Issue.2
, pp. 171-172
-
-
Evans, L.M.1
Casper, E.S.2
Rosenbluth, R.3
-
20
-
-
0033636732
-
Oxaliplatin is active in vitro against human melanoma cell lines: Comparison with cisplatin and carboplatin
-
Mohammed MQ, Retsas S. Oxaliplatin is active in vitro against human melanoma cell lines: comparison with cisplatin and carboplatin. Anticancer Drugs. 2000;11:859-863.
-
(2000)
Anticancer Drugs
, vol.11
, pp. 859-863
-
-
Mohammed, M.Q.1
Retsas, S.2
-
21
-
-
79955977441
-
A phase II trial of oxaliplatin in patients with advanced melanoma 2006 ASCO Annual Meeting Proceedings (Post-meeting Edition)
-
Abstract 18016
-
Lutzky J, Nunez Y, Graham P. A phase II trial of oxaliplatin in patients with advanced melanoma. 2006 ASCO Annual Meeting Proceedings (Post-meeting Edition). J Clin Oncol. 2006;24(suppl):18S. Abstract 18016.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Lutzky, J.1
Nunez, Y.2
Graham, P.3
-
22
-
-
0021275104
-
Vindesine in patients with metastatic malignant melanoma: A Southwest Oncology Group study
-
Quagliana JM, Stephens RL, Baker LH, et al. Vindesine in patients with metastatic malignant melanoma. A Southwest Oncology Group study. J Clin Oncol. 1984;4:316-319. (Pubitemid 14106999)
-
(1984)
Journal of Clinical Oncology
, vol.2
, Issue.4
, pp. 316-319
-
-
Quagliana, J.M.1
Stephens, R.L.2
Baker, L.H.3
Costanzi, J.J.4
-
23
-
-
0026013307
-
A phase II study of Taxol in patients with malignant melanoma
-
Einzig AI, Hochester H, Wiernik PH, et al. A phase II study of Taxol in patients with malignant melanoma. Invest New Drugs. 1991;9:59-64.
-
(1991)
Invest New Drugs
, vol.9
, pp. 59-64
-
-
Einzig, A.I.1
Hochester, H.2
Wiernik, P.H.3
-
24
-
-
0028827484
-
Phase II trial of docetaxel in patients with advanced cutaneous malignant melanoma previously untreated with chemotherapy
-
Bedikian AY, Weiss GR, Legha SS, et al. Phase II trial of docetaxel in patients with advanced cutaneous malignant melanoma previously untreated with chemotherapy. J Clin Oncol. 1995;13:2859-2899.
-
(1995)
J Clin Oncol
, vol.13
, pp. 2859-2899
-
-
Bedikian, A.Y.1
Weiss, G.R.2
Legha, S.S.3
-
25
-
-
0027982416
-
Docetaxel (Taxotere) in advanced malignant melanoma: A phase II study of the EORTC Early Clinical Trials Group
-
Aamdal S, Wolff I, Kaplan S, et al. Docetaxel (Taxotere) in advanced malignant melanoma: a phase II study of the EORTC Early Clinical Trials Group. Eur J Cancer. 1994;30A:1061-1064.
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 1061-1064
-
-
Aamdal, S.1
Wolff, I.2
Kaplan, S.3
-
26
-
-
33846677566
-
Phase II trial of ABI-007 (Abraxane) in previously treated and chemotherapy-naive patients with metastatic melanoma
-
Abstract ABS-0141
-
Hersh E, O'Day S, Gonzalez R, et al. Phase II trial of ABI-007 (Abraxane) in previously treated and chemotherapy-naive patients with metastatic melanoma. Melanoma Res. 2006;16:S78. Abstract ABS-0141.
-
(2006)
Melanoma Res
, vol.16
-
-
Hersh, E.1
O'Day, S.2
Gonzalez, R.3
-
27
-
-
0017754120
-
Results with methyl-CCNU and DTIC in metastatic melanoma
-
Costanza ME, Nathanson L, Schoenfeld D, et al. Results with methyl-CCNU and DTIC in metastatic melanoma. Cancer. 1997;40:1010-1015
-
(1997)
Cancer
, vol.40
, pp. 1010-1015
-
-
Costanza, M.E.1
Nathanson, L.2
Schoenfeld, D.3
-
28
-
-
0025690495
-
Combination chemotherapy of dacarbazine and fotemustine in disseminated malignant melanoma. Experience of the French Study Group
-
Avril MF, Bonneterre J, Delaunay M, et al. Combination chemotherapy of dacarbazine and fotemustine in disseminated malignant melanoma. Experience of the French Study Group. Cancer Chemother Pharmacol. 1990;27: 81-84.
-
(1990)
Cancer Chemother Pharmacol
, vol.27
, pp. 81-84
-
-
Avril, M.F.1
Bonneterre, J.2
Delaunay, M.3
-
29
-
-
0016664212
-
Combination chemotherapy for disseminated malignant melanoma
-
Costanzi JJ, Vaitkevicius VK, Quagliana JM, et al. Combination chemotherapy for disseminated malignant melanoma. Cancer. 1975;35:342-346.
-
(1975)
Cancer
, vol.35
, pp. 342-346
-
-
Costanzi, J.J.1
Vaitkevicius, V.K.2
Quagliana, J.M.3
-
30
-
-
0023719846
-
Evaluation of cis-platinum and DTIC combination chemotherapy in disseminated melanoma. A Southwest Oncology Group Study
-
Fletcher WS, Green S, Fletcher JR, et al. Evaluation of cis-platinum and DTIC combination chemotherapy in disseminated melanoma. A Southwest Oncology Group Study. Am J Clin Oncol. 1988;11:589-593.
-
(1988)
Am J Clin Oncol
, vol.11
, pp. 589-593
-
-
Fletcher, W.S.1
Green, S.2
Fletcher, J.R.3
-
31
-
-
0022526708
-
Combination chemotherapy with dacarbazine and vindesine in the treatment of metastatic malignant melanoma
-
Vorobiof DA, Sarli R, Falkson G. Combination chemotherapy with dacarbazine and vindesine in the treatment of metastatic malignant melanoma.Cancer Treat Rep. 1986;70:927-928. (Pubitemid 16058569)
-
(1986)
Cancer Treatment Reports
, vol.70
, Issue.7
, pp. 927-928
-
-
Vorobiof, D.A.1
Sarli, R.2
Falkson, G.3
-
32
-
-
0021702431
-
Combination chemotherapy with cisplatin, carmustine, dacarbazine, and tamoxifen in metastatic melanoma
-
del Prete SA, Maurer LH, O'Donnell J. Combination chemotherapy with cisplatin, carmustine, dacarbazine and tamoxifen in metastatic melanoma.Cancer Treat Rep. 1984;68:1403-1405. (Pubitemid 15222028)
-
(1984)
Cancer Treatment Reports
, vol.68
, Issue.11
, pp. 1403-1405
-
-
Del Prete, S.A.1
Maurer, L.H.2
O'Donnell, J.3
-
33
-
-
0029097550
-
Dacarbazine, cisplatin and carmustine, with or without tamoxifen, for metastatic melanoma: 5-year followup
-
Lattanzi SC, Tosteson T, Chertoff J, et al. Dacarbazine, cisplatin and carmustine, with or without tamoxifen, for metastatic melanoma: 5-year followup. Melanoma Res. 1995;5:365-369.
-
(1995)
Melanoma Res
, vol.5
, pp. 365-369
-
-
Lattanzi, S.C.1
Tosteson, T.2
Chertoff, J.3
-
34
-
-
8944261598
-
Randomized, double-blind, placebo-controlled trial comparing the response rates of carmustine, dacarbazine, and cisplatin with and without tamoxifen in patients with metastatic melanoma
-
Rusthoven JJ, Quirt IC, Iscoe NA, et al. Randomized, double-blind placebocontrolled trial comparing the response rates of carmustine, dacarbazine and cisplatin with and without tamoxifen in patients with metastatic melanoma. J Clin Oncol. 1996;14:2083-2090. (Pubitemid 26230110)
-
(1996)
Journal of Clinical Oncology
, vol.14
, Issue.7
, pp. 2083-2090
-
-
Rusthoven, J.J.1
Quirt, I.C.2
Iscoe, N.A.3
McCulloch, P.B.4
James, K.W.5
Lohmann, R.C.6
Jensen, J.7
Burdette-Radoux, S.8
Bodurtha, A.J.9
Silver, H.K.B.10
Verma, S.11
Armitage, G.R.12
Zee, B.13
Bennett, K.14
-
35
-
-
0032858487
-
Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma
-
Chapman PB, Einhorn LH, Meyers ML, et al. Phase III multicenter randomized trial of Dartmouth regimen versus dacarbazine in patients with metastatic melanoma. J Clin Oncol. 1999;17:2745-2751. (Pubitemid 29415231)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.9
, pp. 2745-2751
-
-
Chapman, P.B.1
Einhorn, L.H.2
Meyers, M.L.3
Saxman, S.4
Destro, A.N.5
Panageas, K.S.6
Begg, C.B.7
Agarwala, S.S.8
Schuchter, L.M.9
Ernstoff, M.S.10
Houghton, A.N.11
Kirkwood, J.M.12
-
36
-
-
0024448792
-
A prospective evaluation of a triple-drug regimen containing cisplatin, vinblastine, and dacarbazine (CVD) for metastatic melanoma
-
Legha SS, Ring S, Papadopoulos N, et al. A prospective evaluation of a triple-drug regimen containing cisplatin, vinblastine and dacarbazine (CVD) for metastatic melanoma. Cancer. 1989;64:2024-2029. (Pubitemid 19280399)
-
(1989)
Cancer
, vol.64
, Issue.10
, pp. 2024-2029
-
-
Legha, S.S.1
Ring, S.2
Papadopoulos, N.3
Plager, C.4
Chawla, S.5
Benjamin, R.6
-
37
-
-
0000022334
-
Cisplatin (C), Vinblastine (V), and Dacarbazine (D) (CVD) versus dacarbazine alone in metastatic melanoma: Preliminary results of a Phase II Cancer Community Oncology Program (CCOP) trial [abstract]
-
Buzaid AC, Legha S, Winn R, et al. Cisplatin (C), Vinblastine (V), and Dacarbazine (D) (CVD) versus dacarbazine alone in metastatic melanoma: preliminary results of a Phase II Cancer Community Oncology Program (CCOP) trial [abstract]. Proc Am Soc Clin Oncol. 1993;12:389a.
-
(1993)
Proc Am Soc Clin Oncol
, vol.12
-
-
Buzaid, A.C.1
Legha, S.2
Winn, R.3
-
38
-
-
0036274949
-
Phase II study of paclitaxel and carboplatin for malignant melanoma
-
DOI 10.1097/00000421-200206000-00016
-
Hodi FS, Soiffer RJ, Clark J, et al. Phase II study of paclitaxel and carboplatin for malignant melanoma. Am J Clin Oncol. 2002;25:283-286. (Pubitemid 34602552)
-
(2002)
American Journal of Clinical Oncology: Cancer Clinical Trials
, vol.25
, Issue.3
, pp. 283-286
-
-
Hodi, F.S.1
Soiffer, R.J.2
Clark, J.3
Finkelstein, D.M.4
Haluska, F.G.5
-
39
-
-
0142057351
-
Randomized phase II study of weekly paclitaxel versus paclitaxel and carboplatin as second-line therapy in disseminated melanoma: A multicentre trial of the Dermatologic Co-operative Oncology Group (DeCOG)
-
DOI 10.1097/00008390-200310000-00012
-
Zimpfer-Rechner C, Hofmann U, Figl R, et al. Randomized phase II study of weekly paclitaxel versus paclitaxel and carboplatin as second-line therapy in disseminated melanoma: a multicentre trial of the Dermatologic Co-operative Oncology Group (DeCOG). Melanoma Res. 2003;13:531-536. (Pubitemid 37266956)
-
(2003)
Melanoma Research
, vol.13
, Issue.5
, pp. 531-536
-
-
Zimpfer-Rechner, C.1
Hofmann, U.2
Figl, R.3
Becker, J.C.4
Trefzer, U.5
Keller, I.6
Hauschild, A.7
Schadendorf, D.8
-
40
-
-
30744461590
-
Combination of and paclitaxel and carboplatin as second-line therapy for patients with metastatic melanoma
-
DOI 10.1002/cncr.21611
-
Rao RD, Holtan SG, Ingle JN, et al. Combination of paclitaxel and carboplatin as second-line therapy for patients with metastatic melanoma. Cancer. 2006;106:375-382. (Pubitemid 43100447)
-
(2006)
Cancer
, vol.106
, Issue.2
, pp. 375-382
-
-
Rao, R.D.1
Holtan, S.G.2
Ingle, J.N.3
Croghan, G.A.4
Kottschade, L.A.5
Creagan, E.T.6
Kaur, J.S.7
Pitot, H.C.8
Markovic, S.N.9
-
41
-
-
0026625695
-
Treatment of metastatic malignant melanoma with dacarbazine plus tamoxifen
-
Cocconi G, Bella M, Calabresi F, et al. Treatment of metastatic malignant melanoma with dacarbazine plus tamoxifen. N Engl J Med. 1992;327:516-523.
-
(1992)
N Engl J Med
, vol.327
, pp. 516-523
-
-
Cocconi, G.1
Bella, M.2
Calabresi, F.3
-
42
-
-
0025837770
-
Improved results with the addition of interferon alfa-2b to dacarbazine in the treatment of patients with metastatic malignant melanoma
-
Falkson CI, Falkson G, Falkson HC. Improved results with the addition of interferon alfa-2b to dacarbazine in the treatment of patients with metastatic malignant melanoma. J Clin Oncol. 1991;9:1403-1408.
-
(1991)
J Clin Oncol
, vol.9
, pp. 1403-1408
-
-
Falkson, C.I.1
Falkson, G.2
Falkson, H.C.3
-
43
-
-
0141563757
-
Use of tamoxifen in the treatment of malignant melanoma: Systematic review and metaanalysis of randomized controlled trials
-
DOI 10.1002/cncr.11644
-
Lens MB, Reiman T, Husain AF. Use of tamoxifen in the treatment of malignant melanoma. Systematic review and meta-analysis of randomized controlled trial. Cancer. 2003;98:1355-1361. (Pubitemid 37151488)
-
(2003)
Cancer
, vol.98
, Issue.7
, pp. 1355-1361
-
-
Lens, M.B.1
Reiman, T.2
Husain, A.F.3
-
44
-
-
0141688331
-
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma
-
DOI 10.1200/JCO.2003.02.061
-
Hwu WJ, Krown SE, Menell JH, et al. Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma. J Clin Oncol. 2003; 21:3351-3356. (Pubitemid 46606269)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.17
, pp. 3351-3356
-
-
Hwu, W.-J.1
Krown, S.E.2
Menell, J.H.3
Panageas, K.S.4
Merrell, J.5
Lamb, L.A.6
Williams, L.J.7
Quinn, C.J.8
Foster, T.9
Chapman, P.B.10
Livingston, P.O.11
Wolchok, J.D.12
Houghton, A.N.13
-
45
-
-
0037676126
-
Randomized phase II study of temozolomide given every 8 hours or daily with either interferon Alfa-2b or thalidomide in metastatic malignant melanoma
-
DOI 10.1200/JCO.2003.10.039
-
Danson S, Lorigan P, Arance A, et al. Randomized phase II study of temozolomide given every 8 hours or daily with either interferon alfa-2b or thalidomide in metastatic malignant melanoma. J Clin Oncol. 2003;21:2551-2557. (Pubitemid 46606337)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.13
, pp. 2551-2557
-
-
Danson, S.1
Lorigan, P.2
Arance, A.3
Clamp, A.4
Ranson, M.5
Hodgetts, J.6
Lomax, L.7
Ashcroft, L.8
Thatcher, N.9
Middleton, M.R.10
-
46
-
-
20444387198
-
Temozolomide plus thalidomide in patients with brain metastases from melanoma: A phase II study
-
DOI 10.1002/cncr.21081
-
Hwu WJ, Lis E, Menell JH, et al. Temozolomide plus thalidomide in patients with brain metastases from melanoma: a phase II study. Cancer. 2005;103:2590-2597. (Pubitemid 40800539)
-
(2005)
Cancer
, vol.103
, Issue.12
, pp. 2590-2597
-
-
Hwu, W.-J.1
Lis, E.2
Menell, J.H.3
Panageas, K.S.4
Lamb, L.A.5
Merrell, J.6
Williams, L.J.7
Krown, S.E.8
Chapman, P.B.9
Livingston, P.O.10
Wolchok, J.D.11
Houghton, A.N.12
-
47
-
-
51649113588
-
A Cytokine Working Group phase II study of temozolomide (TMZ), thalidomide (THAL) and whole brain radiation therapy (WBRT) for patients with brain metastases from melanoma (2005 ASCO Annual Meeting Proceedings)
-
Abstract 7552
-
Atkins MB, Sosman J, Agarwala S, et al. A Cytokine Working Group phase II study of temozolomide (TMZ), thalidomide (THAL) and whole brain radiation therapy (WBRT) for patients with brain metastases from melanoma (2005 ASCO Annual Meeting Proceedings). J Clin Oncol. 2005;23(suppl):16S. Abstract 7552.
-
(2005)
J Clin Oncol
, vol.23
, Issue.SUPPL.
-
-
Atkins, M.B.1
Sosman, J.2
Agarwala, S.3
-
48
-
-
0027254190
-
A Phase II study of dacarbazine and cisplatin in combination with outpatient administered interleukin-2 in metastatic malignant melanoma
-
DOI 10.10 02/1097-014 2(1993 0601)71:11<35 20::AID-CNC R2820711 110>3.0.CO;2-A
-
Flaherty LE, Robinson W, Redman BG, et al. A phase II study of dacarbazine and cisplatin in combination with outpatient administered interleukin-2 in metastatic malignant melanoma. Cancer. 1993;71:3520-3525. (Pubitemid 23152659)
-
(1993)
Cancer
, vol.71
, Issue.11
, pp. 3520-3525
-
-
Flaherty, L.E.1
Robinson, W.2
Redman, B.G.3
Gonzalez, R.4
Martino, S.5
Kraut, M.6
Valdivieso, M.7
Rudolph, A.R.8
-
49
-
-
0028145101
-
Multiinstitutional phase II trial of intensive combination chemoimmunotherapy for metastatic melanoma
-
Atkins MB, O'Boyle KR, Sosma JA, et al. Multiinstitutional phase II trial of intensive combination chemoimmunotherapy for metastatic melanoma. J Clin Oncol. 1994;12:1553-1560. (Pubitemid 24244989)
-
(1994)
Journal of Clinical Oncology
, vol.12
, Issue.8
, pp. 1553-1560
-
-
Atkins, M.B.1
O'Boyle, K.R.2
Sosman, J.A.3
Weiss, G.R.4
Margolin, K.A.5
Ernest, M.L.6
Kappler, K.7
Mier, J.W.8
Sparano, J.A.9
Fisher, R.I.10
Eckardt, J.R.11
Pereira, C.12
Aronson, F.R.13
-
50
-
-
0031805726
-
Development of a biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, dacarbazine, interferon alfa, and interleukin-2 for patients with metastatic melanoma
-
Legha SS, Ring S, Eton O, et al. Development of a biochemotherapy regimen with concurrent administration of cisplatin, vinblastine, dacarbazine, interferon alfa, and interleukin-2 for patients with metastatic melanoma. J Clin Oncol. 1998;16:1752-1759. (Pubitemid 28234719)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.5
, pp. 1752-1759
-
-
Legha, S.S.1
Ring, S.2
Eton, O.3
Bedikian, A.4
Buzaid, A.C.5
Plager, C.6
Papadopoulos, N.7
-
51
-
-
0032850026
-
Advantages of concurrent biochemotherapy modified by decrescendo interleukin-2, granulocyte colony-stimulating factor, and tamoxifen for patients with metastatic melanoma
-
O'Day SJ, Gammon G, Boasberg PD, et al. Advantages of concurrent biochemotherapy modifled by decrescendo interleukin-2, granulocyte colony-stimulating factor and tamoxifen for patients with metastatic melanoma. J Clin Oncol. 1999;17:2752-2761. (Pubitemid 29415232)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.9
, pp. 2752-2761
-
-
O'Day, S.J.1
Gammon, G.2
Boasberg, P.D.3
Martin, M.A.4
Kristedja, T.S.5
Guo, M.6
Stern, S.7
Edwards, S.8
Fournier, P.9
Weisberg, M.10
Cannon, M.11
Fawzy, N.W.12
Johnson, T.D.13
Essner, R.14
Foshag, L.J.15
Morton, D.L.16
-
52
-
-
0031718717
-
Results of interleukin-2-based treatment in advanced melanoma: A case record-based analysis of 631 patients
-
Keilholz U, Conradt C, Legha SS, et al. Results of interleukin-2-based treatment in advanced melanoma: a case record-based analysis of 631 patients. J Clin Oncol. 1998;16:2921-2929. (Pubitemid 28417410)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.9
, pp. 2921-2929
-
-
Keilholz, U.1
Conradt, C.2
Legha, S.S.3
Khayat, D.4
Scheibenbogen, C.5
Thatcher, N.6
Goey, S.H.7
Gore, M.8
Dorval, T.9
Hancock, B.10
Punt, C.J.A.11
Dummer, R.12
Avril, M.-F.13
Brocker, E.B.14
Benhammouda, A.15
Eggermont, A.M.M.16
Pritsch, M.17
-
53
-
-
27244432257
-
Dacarbazine, cisplatin, and interferon-Alfa-2b with or without interleukin-2 in metastatic melanoma: A randomized phase III trial (18951) of the European Organisation for Research and Treatment of Cancer Melanoma Group
-
DOI 10.1200/JCO.2005.03.202
-
Keilholz U, Punt CJ, Gore M, et al. Dacarbazine, cisplatin and interferonalfa-2b with or without interleukin-2 in metastatic melanoma: a randomized phase III trial (18951) of the European Organization for Research and Treatment of Cancer Melanoma Group. J Clin Oncol. 2005;23:6747-6755. (Pubitemid 46190270)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.27
, pp. 6747-6755
-
-
Keilholz, U.1
Punt, C.J.A.2
Gore, M.3
Kruit, W.4
Patel, P.5
Lienard, D.6
Thomas, J.7
Proebstle, T.M.8
Schmittel, A.9
Schadendorf, D.10
Velu, T.11
Negrier, S.12
Kleeberg, U.13
Lehman, F.14
Suciu, S.15
Eggermont, A.M.M.16
-
54
-
-
0342894822
-
Interferon alfa-2a and interleukin-2 with or without cisplatin in metastatic melanoma: A randomized trial of the European organization for research and treatment of cancer melanoma cooperative group
-
Keilholz U, Goey SH, Punt CJ, et al. Interferon alfa-2a and interleukin-2 with or without cisplatin in metastatic melanoma: a randomized trial of the European Organization for Research and Treatment of Cancer Melanoma Cooperative Group. J Clin Oncol. 1997;15:2579-2588. (Pubitemid 27289888)
-
(1997)
Journal of Clinical Oncology
, vol.15
, Issue.7
, pp. 2579-2588
-
-
Keilholz, U.1
Goey, S.H.2
Punt, C.J.A.3
Proebstle, T.M.4
Salzmann, R.5
Scheibenbogen, C.6
Schadendorf, D.7
Lienard, D.8
Enk, A.9
Dummer, R.10
Hantich, B.11
Geueke, A.-M.12
Eggermont, A.M.M.13
-
55
-
-
0032976897
-
Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b
-
Rosenberg SA, Yang JC, Schwartzentruber DJ, et al. Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b. J Clin Oncol. 1999;17:968-975. (Pubitemid 29109330)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.3
, pp. 968-975
-
-
Rosenberg, S.A.1
Yang, J.C.2
Schwartzentruber, D.J.3
Hwu, P.4
Marincola, F.M.5
Topalian, S.L.6
Seipp, C.A.7
Einhorn, J.H.8
White, D.E.9
Steinberg, S.M.10
-
56
-
-
1642275644
-
A prospective randomized phase III trial of concurrent biochemotherapy (BCT) with cisplatin, vinblastine, dacarbazine (CVD), IL-2 and interferon alpha-2b (IFN) versus CVD alone in patients with metastatic melanoma (E3695): An ECOG-coordinated intergroup trial
-
Abstract 2847
-
Atkins MB, Lee S, Flaherty LE, et al. A prospective randomized phase III trial of concurrent biochemotherapy (BCT) with cisplatin, vinblastine, dacarbazine (CVD), IL-2 and interferon alpha-2b (IFN) versus CVD alone in patients with metastatic melanoma (E3695): an ECOG-coordinated intergroup trial. Proc Am Soc Clin Oncol. 2003;22:708. Abstract 2847.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 708
-
-
Atkins, M.B.1
Lee, S.2
Flaherty, L.E.3
-
57
-
-
0037089629
-
Sequential biochemotherapy versus chemotherapy for metastatic melanoma: Results from a phase III randomized trial
-
DOI 10.1200/JCO.2002.07.044
-
Eton O, Legha SS, Bedikian AY, et al. Sequential biochemotherapy versus chemotherapy for metastatic melanoma: results from a phase III randomized trial. J Clin Oncol. 2002;20:2045-2052. (Pubitemid 34408794)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.8
, pp. 2045-2052
-
-
Eton, O.1
Legha, S.S.2
Bedikian, A.Y.3
Lee, J.J.4
Buzaid, A.C.5
Hodges, C.6
Ring, S.E.7
Papadopoulos, N.E.8
Plager, C.9
East, M.J.10
Zhan, F.11
Benjamin, R.S.12
-
58
-
-
53949108399
-
Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): A trial coordinated by the Eastern Cooperative Oncology Group
-
Atkins MB, Hsu J, Lee S, et al. Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): a trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol. 2008;26:5748-5754.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5748-5754
-
-
Atkins, M.B.1
Hsu, J.2
Lee, S.3
-
59
-
-
56749158015
-
Immunoembolization of malignant liver tumors, including uveal melanoma, using granulocyte-macrophage colony-stimulating factor
-
Sato T, Eschelman DJ, Gonsalves CF, et al. Immunoembolization of malignant liver tumors, including uveal melanoma, using granulocyte-macrophage colony-stimulating factor. J Clin Oncol. 2008;26:5436-4542.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5436-4542
-
-
Sato, T.1
Eschelman, D.J.2
Gonsalves, C.F.3
-
60
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
DOI 10.1158/0008-5472.CAN-04-1443
-
Wilhelm SM, Carter C, Tang L, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 2004;64:7099-7109. (Pubitemid 39331023)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
Wilkie, D.4
McNabola, A.5
Rong, H.6
Chen, C.7
Zhang, X.8
Vincent, P.9
McHugh, M.10
Cao, Y.11
Shujath, J.12
Gawlak, S.13
Eveleigh, D.14
Rowley, B.15
Liu, L.16
Adnane, L.17
Lynch, M.18
Auclair, D.19
Taylor, I.20
Gedrich, R.21
Voznesensky, A.22
Riedl, B.23
Post, L.E.24
Bollag, G.25
Trail, P.A.26
more..
-
61
-
-
4344584872
-
B-RAF is a therapeutic target in melanoma
-
DOI 10.1038/sj.onc.1207785
-
Karasarides M, Chiloeches A, Hayward R, et al. B-RAF is a therapeutic target in melanoma. Oncogene. 2004;23:6292-6298. (Pubitemid 39215299)
-
(2004)
Oncogene
, vol.23
, Issue.37
, pp. 6292-6298
-
-
Karasarides, M.1
Chiloeches, A.2
Hayward, R.3
Niculescu-Duvaz, D.4
Scanlon, I.5
Friedlos, F.6
Ogilvie, L.7
Hedley, D.8
Martin, J.9
Marshall, C.J.10
Springer, C.J.11
Marais, R.12
-
62
-
-
20044382799
-
Phase I clinical and pharmacokinetic study of the novel raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors
-
DOI 10.1200/JCO.2005.06.124
-
Strumberg D, Richly H, Hilger RA, et al. Phase I clinical and pharmacokinetic study of the novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. J Clin Oncol. 2005;23:965-972. (Pubitemid 46202316)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.5
, pp. 965-972
-
-
Strumberg, D.1
Richly, H.2
Hilger, R.A.3
Schleucher, N.4
Korfee, S.5
Tewes, M.6
Faghih, M.7
Brendel, E.8
Voliotis, D.9
Haase, C.G.10
Schwartz, B.11
Awada, A.12
Voigtmann, R.13
Scheulen, M.E.14
Seeber, S.15
-
63
-
-
9744239081
-
BAY 43-9006 in patients with advanced melanoma: The Royal Marsden experience 2004 ASCO Annual Meeting Proceedings (Post-meeting Edition)
-
Abstract 7506
-
Ahmad T, Marais R, Pyle L, et al. BAY 43-9006 in patients with advanced melanoma: the Royal Marsden experience. 2004 ASCO Annual Meeting Proceedings (Post-meeting Edition). J Clin Oncol. 2004;22(suppl):14S. Abstract 7506.
-
(2004)
J Clin Oncol
, vol.22
, Issue.SUPPL.
-
-
Ahmad, T.1
Marais, R.2
Pyle, L.3
-
64
-
-
33748325763
-
Sorafenib in advanced melanoma: A Phase II randomised discontinuation trial analysis
-
DOI 10.1038/sj.bjc.6603291, PII 6603291
-
Eisen T, Ahmad T, Flaherty KT, et al. Sorafenib in advanced melanoma: a phase II randomized discontinuation trial analysis. Br J Cancer. 2006;95:581-586. (Pubitemid 44325897)
-
(2006)
British Journal of Cancer
, vol.95
, Issue.5
, pp. 581-586
-
-
Eisen, T.1
Ahmad, T.2
Flaherty, K.T.3
Gore, M.4
Kaye, S.5
Marais, R.6
Gibbens, I.7
Hackett, S.8
James, M.9
Schuchter, L.M.10
Nathanson, K.L.11
Xia, C.12
Simantov, R.13
Schwartz, B.14
Poulin-Costello, M.15
O'Dwyer, P.J.16
Ratain, M.J.17
-
65
-
-
16844376769
-
Phase I/II trial of BAY 43-9006, carboplatin (C) and paclitaxel (P) demonstrates preliminary antitumor activity in the expansion cohort of patients with metastatic melanoma 2004 ASCO Annual Meeting Proceedings (Post-meeting Edition)
-
Abstract 7507
-
Flaherty KT, Brose M, Schucter L, et al. Phase I/II trial of BAY 43-9006, carboplatin (C) and paclitaxel (P) demonstrates preliminary antitumor activity in the expansion cohort of patients with metastatic melanoma. 2004 ASCO Annual Meeting Proceedings (Post-meeting Edition). J Clin Oncol. 2004; 22(suppl):14S. Abstract 7507.
-
(2004)
J Clin Oncol
, vol.22
, Issue.SUPPL.
-
-
Flaherty, K.T.1
Brose, M.2
Schucter, L.3
-
66
-
-
33748349941
-
Preliminary results of a randomized phase II study comparing two schedules of temozolomide in combination with sorafenib in patients with advanced melanoma 2005 ASCO Annual Meeting Proceedings
-
Abstract 8009
-
Amaravadi R, Schucter LM, Kramer A, et al. Preliminary results of a randomized phase II study comparing two schedules of temozolomide in combination with sorafenib in patients with advanced melanoma. 2005 ASCO Annual Meeting Proceedings. J Clin Oncol. 2006;24(suppl):18S. Abstract 8009.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Amaravadi, R.1
Schucter, L.M.2
Kramer, A.3
-
67
-
-
33846856501
-
Phase I clinical trial of STA-4783 in combination with paclitaxel in patients with refractory solid tumors
-
DOI 10.1158/1078-0432.CCR-06-0964
-
Berkenblit A, Eder JP Jr, Ryan DP, et al. Phase I clinical trial of STA-4783 in combination with paclitaxel in patients with refractory solid tumors. Clin Cancer Res. 2007;13(2 pt 1):584-590. (Pubitemid 46225365)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.2
, pp. 584-590
-
-
Berkenblit, A.1
Eder Jr., J.P.2
Ryan, D.P.3
Seiden, M.V.4
Tatsuta, N.5
Sherman, M.L.6
Dahl, T.A.7
Dezube, B.J.8
Supko, J.G.9
-
68
-
-
41149116159
-
Subgroup analysis of efflcacy and safety analysis of a randomized doubleblinded controlled phase II study of STA-4783 in combination with paclitaxel in patients with metastatic melanoma [abstract]
-
O'Day S, Gonzalez R, Lawson D, et al; 4783 Melanoma Study Group l. Subgroup analysis of efflcacy and safety analysis of a randomized, doubleblinded controlled phase II study of STA-4783 in combination with paclitaxel in patients with metastatic melanoma [abstract]. J Clin Oncol. 2007;25:479s.
-
(2007)
J Clin Oncol
, vol.25
-
-
O'Day, S.1
Gonzalez, R.2
Lawson, D.3
-
69
-
-
33646268037
-
Multicenter phase II trial of high-dose imatinib mesylate in metastatic melanoma: Significant toxicity with no clinical efficacy
-
DOI 10.1002/cncr.21834
-
Wyman K, Atkins MB, Prieto V, et al. Multicenter phase II trial of high-dose imatinib mesylate in metastatic melanoma: signiflcant toxicity with no clinical efflcacy. Cancer. 2006;106:2005-2011. (Pubitemid 43673217)
-
(2006)
Cancer
, vol.106
, Issue.9
, pp. 2005-2011
-
-
Wyman, K.1
Atkins, M.B.2
Prieto, V.3
Eton, O.4
McDermott, D.F.5
Hubbard, F.6
Byrnes, C.7
Sanders, K.8
Sosman, J.A.9
-
70
-
-
0003311698
-
MDX-010 (human anti-CTLA4): A phase i trial in malignant melanoma-abstract
-
Abstract 56
-
Tchekmedyian S, Glasby J, Korman A, et al. MDX-010 (human anti-CTLA4): a phase I trial in malignant melanoma-abstract-. Proc Am Soc Clin Oncol. 2002;21:Abstract 56.
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Tchekmedyian, S.1
Glasby, J.2
Korman, A.3
-
71
-
-
32644467549
-
Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206
-
DOI 10.1200/JCO.2005.01.109
-
Ribas A, Camacho LH, Lopez-Berestein G, et al. Antitumor activity in melanoma and anti-self responses in a phase I trial with the anti-cytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206. J Clin Oncol. 2005;23:8968-8977. (Pubitemid 46217464)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.35
, pp. 8968-8977
-
-
Ribas, A.1
Camacho, L.H.2
Lopez-Berestein, G.3
Pavlov, D.4
Bulanhagui, C.A.5
Millham, R.6
Comin-Anduix, B.7
Reuben, J.M.8
Seja, E.9
Parker, C.A.10
Sharma, A.11
Glaspy, J.A.12
Gomez-Navarro, J.13
-
72
-
-
79955975297
-
A phase II, randomized multi-center study of MDX-010 alone or in combination with dacarbazine (DTIC) in stage IV metastatic malignant melanoma 2004 ASCO Annual Meeting Proceedings (Post-meeting Edition)
-
Abstract 7511
-
Hersh EM, Weber JJ, Powderly J, et al. A phase II, randomized multi-center study of MDX-010 alone or in combination with dacarbazine (DTIC) in stage IV metastatic malignant melanoma. 2004 ASCO Annual Meeting Proceedings (Post-meeting Edition). J Clin Oncol. 2004;22(suppl):14S. Abstract 7511.
-
(2004)
J Clin Oncol
, vol.22
, Issue.SUPPL.
-
-
Hersh, E.M.1
Weber, J.J.2
Powderly, J.3
-
73
-
-
33744789014
-
Durable responses and long-term progression-free survival observed in a phase II study of MDX-010 alone or in combination with dacarbazine (DTIC) in metastatic melanoma
-
Abstract 7525
-
Fischkoff SA, Hersh E, Weber J, et al. Durable responses and long-term progression-free survival observed in a phase II study of MDX-010 alone or in combination with dacarbazine (DTIC) in metastatic melanoma. Proc Am Soc Clin Oncol. 2005;23:716S. Abstract 7525.
-
(2005)
Proc Am Soc Clin Oncol
, vol.23
-
-
Fischkoff, S.A.1
Hersh, E.2
Weber, J.3
-
74
-
-
41149164223
-
The efflcacy and safety of ipilimumab (MDX-010) in patients with unresectable stage III or stage IV malignant melanoma. ASCO Annual Meeting Proceedings Part i
-
Abstract 8523
-
Weber JS, Hersh EM, Yellin M, et al. The efflcacy and safety of ipilimumab (MDX-010) in patients with unresectable stage III or stage IV malignant melanoma. ASCO Annual Meeting Proceedings Part I. J Clin Oncol. 2007;25(18S):Abstract 8523.
-
(2007)
J Clin Oncol
, vol.25
-
-
Weber, J.S.1
Hersh, E.M.2
Yellin, M.3
-
75
-
-
79955980112
-
-
Poster presented at: European Society for Medical Oncology; Stockholm, Sweden; September 15, 2008. Poster no. 776PD (Study)
-
Maio M, Hoos A, Ibrahim R, et al. Efficacy and safety of ipilimumab in patients with advanced melanoma who had progressed on one or more prior therapies: results from a single-arm, multicenter study. Poster presented at: European Society for Medical Oncology; Stockholm, Sweden; September 15, 2008. Poster no. 776PD (Study 008).
-
Efficacy and Safety of Ipilimumab in Patients with Advanced Melanoma Who Had Progressed on One or More Prior Therapies: Results from A Single-arm, multicenter study
-
-
Maio, M.1
Hoos, A.2
Ibrahim, R.3
-
76
-
-
79955968500
-
-
Paper presented at: European Society for Medical Oncology; Stockholm Sweden; September 15, Oral Presentation No. 769O (Study 022)
-
Lebbe C, Hoos A, Chin K, et al. Effect of dose on efflcacy and safety in ipilimumab-treated patients with advanced melanoma: results from a phase II, randomized, dose-ranging study. Paper presented at: European Society for Medical Oncology; Stockholm, Sweden; September 15, 2008. Oral Presentation No. 769O (Study 022).
-
(2008)
Effect of Dose on Efflcacy and Safety in Ipilimumab-treated Patients with Advanced Melanoma: Results from A Phase II Randomized Dose-ranging Study
-
-
Lebbe, C.1
Hoos, A.2
Chin, K.3
-
78
-
-
55949137090
-
Phase III, open label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (TMZ or DTIC) in patients with advanced melanoma
-
Abstract LBA9011
-
Ribas A, Hauschild A, Kefford R, et al. Phase III, open label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (TMZ or DTIC) in patients with advanced melanoma. J Clin Oncol. 2008;26(suppl): Abstract LBA9011.
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Ribas, A.1
Hauschild, A.2
Kefford, R.3
-
79
-
-
27444440093
-
Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer
-
Blansfleld JA, Beck KE, Tran K, et al. Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer. J Immunother. 2005;28:593-598. (Pubitemid 41533093)
-
(2005)
Journal of Immunotherapy
, vol.28
, Issue.6
, pp. 593-598
-
-
Blansfield, J.A.1
Beck, K.E.2
Tran, K.3
Yang, J.C.4
Hughes, M.S.5
Kammula, U.S.6
Royal, R.E.7
Topalian, S.L.8
Haworth, L.R.9
Levy, C.10
Rosenberg, S.A.11
Sherry, R.M.12
-
80
-
-
33750600634
-
Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: The oblimersen melanoma study group
-
DOI 10.1200/JCO.2006.06.0483
-
Bedikian AY, Millward M, Pehamberger H, et al. Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group. J Clin Oncol. 2006;24:4738-4745. (Pubitemid 46630937)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.29
, pp. 4738-4745
-
-
Bedikian, A.Y.1
Millward, M.2
Pehamberger, H.3
Conry, R.4
Gore, M.5
Trefzer, U.6
Pavlick, A.C.7
DeConti, R.8
Hersh, E.M.9
Hersey, P.10
Kirkwood, J.M.11
Haluska, F.G.12
-
81
-
-
33750584886
-
Reaching first base in the treatment of metastatic melanoma
-
DOI 10.1200/JCO.2006.07.3593
-
Eggermont AM. Reaching flrst base in the treatment of metastatic melanoma [editorial]. J Clin Oncol. 2006;24:4673-4674. (Pubitemid 46630929)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.29
, pp. 4673-4674
-
-
Eggermont, A.M.M.1
-
82
-
-
0033866240
-
In vivo therapy of malignant melanoma by means of antagonists of αv integrins
-
DOI 10.10 02/1097-021 5(20000 901)87:5<716::A ID-IJC1 4>3.0.CO;2-R
-
Mitjans F, Meyer T, Fittschen C, et al. In vivo therapy of malignant melanoma by means of antagonists of aV integrins. Int J Cancer. 2000;87:716-723. (Pubitemid 30620415)
-
(2000)
International Journal of Cancer
, vol.87
, Issue.5
, pp. 716-723
-
-
Mitjans, F.1
Meyer, T.2
Fittschen, C.3
Goodman, S.4
Jonczyk, A.5
Marshall, J.F.6
Reyes, G.7
Piulats, J.8
-
83
-
-
33645549711
-
A phase II, randomized, open-label study evaluating the antitumor activity of MEDI-522, a humanized monoclonal antibody directed against the human metastatic melanoma (MM)
-
Abstract 7507
-
Hersey P, Sosman J, O'Day S, et al. A phase II, randomized, open-label study evaluating the antitumor activity of MEDI-522, a humanized monoclonal antibody directed against the human metastatic melanoma (MM). J Clin Oncol. 2005;23:711S. sAbstract 7507.
-
(2005)
J Clin Oncol
, vol.23
-
-
Hersey, P.1
Sosman, J.2
O'Day, S.3
-
84
-
-
42549159630
-
Suppression of melanomaassociated neoangiogenesis by bevacizumab
-
Jaissle GB, Ulmer A, Henke-Fahle S, et al. Suppression of melanomaassociated neoangiogenesis by bevacizumab. Arch Dermatol. 2008;144: 525-527.
-
(2008)
Arch Dermatol
, vol.144
, pp. 525-527
-
-
Jaissle, G.B.1
Ulmer, A.2
Henke-Fahle, S.3
-
85
-
-
38749122676
-
Phase II trial of carboplatin, weekly paclitaxel, and biweekly bevacizumab in patients with unresectable stage IV melanoma. ASCO Annual Meeting Proceedings Part i
-
Abstract 8560
-
Perez DG, Suman V, Amatruda T, et al. Phase II trial of carboplatin, weekly paclitaxel, and biweekly bevacizumab in patients with unresectable stage IV melanoma. ASCO Annual Meeting Proceedings Part I. J Clin Oncol. 2007; 25(suppl):Abstract 8560.
-
(2007)
J Clin Oncol
, vol.25
, Issue.SUPPL.
-
-
Perez, D.G.1
Suman, V.2
Amatruda, T.3
-
86
-
-
59349111637
-
Axitinib (AG-013736) in patients with metastatic melanoma: A phase II study
-
Abstract 9006
-
Fruehauf JP, Lutzky J, McDermott CK, et al. Axitinib (AG-013736) in patients with metastatic melanoma: a phase II study. J Clin Oncol. 2008; 26(suppl):Abstract 9006.
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Fruehauf, J.P.1
Lutzky, J.2
McDermott, C.K.3
-
87
-
-
33750266504
-
Phase II trial of the mTOR inhibitor everolimus (RAD-001) in metastatic melanoma. ASCO Annual Meeting Proceedings Part i
-
Abstract 8043
-
Rao RD, Windschitl HE, Allred JB, et al. Phase II trial of the mTOR inhibitor everolimus (RAD-001) in metastatic melanoma. ASCO Annual Meeting Proceedings Part I. J Clin Oncol. 2006;24(suppl):Abstract 8043.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Rao, R.D.1
Windschitl, H.E.2
Allred, J.B.3
-
88
-
-
71949120742
-
Phase II trial of bevacizumab and everolimus in the treatment of patients with metastatic melanoma: Preliminary results
-
Abstract 9027
-
Peyton JD, Spigel DR, Burris HA, et al. Phase II trial of bevacizumab and everolimus in the treatment of patients with metastatic melanoma: preliminary results. J Clin Oncol. 2009;27(suppl):Abstract 9027.
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL.
-
-
Peyton, J.D.1
Spigel, D.R.2
Burris, H.A.3
-
90
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
DOI 10.1126/science.1129003
-
Morgan RA, Dudley ME, Wunderlich JR, et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science. 2006;314:126-129. (Pubitemid 44547756)
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
Hughes, M.S.4
Yang, J.C.5
Sherry, R.M.6
Royal, R.E.7
Topalian, S.L.8
Kammula, U.S.9
Restifo, N.P.10
Zheng, Z.11
Nahvi, A.12
De Vries, C.R.13
Rogers-Freezer, L.J.14
Mavroukakis, S.A.15
Rosenberg, S.A.16
-
91
-
-
55949125601
-
Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative chemoradiation preparative regimens
-
Dudley ME, Yang JC, Sherry R, et al. Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. J Clin Oncol. 2008;26:5233-5339.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5233-5339
-
-
Dudley, M.E.1
Yang, J.C.2
Sherry, R.3
-
93
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
DOI 10.1038/nature00766
-
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature. 2002;417:949-954. (Pubitemid 34716871)
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
Hawes, R.17
Hughes, J.18
Kosmidou, V.19
Menzies, A.20
Mould, C.21
Parker, A.22
Stevens, C.23
Watt, S.24
Hooper, S.25
Wilson, R.26
Jayatilake, H.27
Gusterson, B.A.28
Cooper, C.29
Shipley, J.30
Hargrave, D.31
Pritchard-Jones, K.32
Maitland, N.33
Chenevix-Trench, G.34
Riggins, G.J.35
Bigner, D.D.36
Palmleri, G.37
Cossu, A.38
Flanagan, A.39
Nicholson, A.40
Ho, J.W.C.41
Leung, S.Y.42
Yuen, S.T.43
Weber, B.L.44
Seigler, H.F.45
Darrow, T.L.46
Paterson, H.47
Marais, R.48
Marshall, C.J.49
Wooster, R.50
Stratton, M.R.51
Futreal, P.A.52
more..
-
94
-
-
31144453233
-
BRAF mutation predicts sensitivity to MEK inhibition
-
DOI 10.1038/nature04304, PII NATURE04304
-
Solit DB, Garraway LA, Pratilas CA, et al. BRAF mutation predicts sensitivity to MEK inhibition. Nature. 2006;439:358-362. (Pubitemid 43128863)
-
(2006)
Nature
, vol.439
, Issue.7074
, pp. 358-362
-
-
Solit, D.B.1
Garraway, L.A.2
Pratilas, C.A.3
Sawai, A.4
Getz, G.5
Basso, A.6
Ye, Q.7
Lobo, J.M.8
She, Y.9
Osman, I.10
Golub, T.R.11
Sebolt-Leopold, J.12
Sellers, W.R.13
Rosen, N.14
-
95
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
DOI 10.1056/NEJMoa050092
-
Curtin JA, Fridlyand J, Kageshita T, et al. Distinct sets of genetic alterations in melanoma. N Engl J Med. 2005;353:2135-2147. (Pubitemid 41653105)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.20
, pp. 2135-2147
-
-
Curtin, J.A.1
Fridlyand, J.2
Kageshita, T.3
Patel, H.N.4
Busam, K.J.5
Kutzner, H.6
Cho, K.-H.7
Aiba, S.8
Brocker, E.-B.9
LeBoit, P.E.10
Pinkel, D.11
Bastian, B.C.12
-
96
-
-
33749021085
-
Somatic activation of KIT in distinct subtypes of melanoma
-
DOI 10.1200/JCO.2006.06.2984
-
Curtin JA, Busam K, Pinkel D, et al. Somatic activation of KIT in distinct subtypes of melanoma. J Clin Oncol. 2006;24:4340-4346. (Pubitemid 46630793)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.26
, pp. 4340-4346
-
-
Curtin, J.A.1
Busam, K.2
Pinkel, D.3
Bastian, B.C.4
|