Age-related EBV-associated lymphoproliferative disorders in theWestern population: A spectrum of reactive lymphoid hyperplasia and lymphoma

Blood

Volumn 117, Issue 18, 2011, Pages 4726-4735

  Dojcinov, Stefan D ^a   Venkataraman, Girish ^b,f   Pittaluga, Stefania ^b   Wlodarska, Iwona ^c   Schrager, Jeffrey A ^b,e   Raffeld, Mark ^b   Hills, Robert K ^d   Jaffe, Elaine S ^b  

^a UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^e Hematopathology/Oncology Services   (United States)

^f LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN; TRANSCRIPTION FACTOR PAX5; VIRUS RNA;

ADULT; AGED; ARTICLE; B LYMPHOCYTE; CLINICAL FEATURE; CLONAL VARIATION; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; EPSTEIN BARR VIRUS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN GENE; IMMUNOPATHOLOGY; IMMUNOPHENOTYPING; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOSURVEILLANCE; INTERPHASE; LARGE CELL LYMPHOMA; LYMPHOCYTE PROLIFERATION; LYMPHOID HYPERPLASIA; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; TREATMENT RESPONSE; ULCER;

EID: 79955950110     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-12-323238     Document Type: Article

References (39)

1. Hislop AD, Taylor GS, Sauce D, Rickinson AB. Cellular responses to viral infection in humans: lessons from Epstein-Barr virus. Annu Rev Immunol. 2007;25:587-617. (Pubitemid 46697918)
2. Shimoyama Y, Yamamoto K, Asano N, Oyama T, Kinoshita T, Nakamura S. Age-related Epstein- Barr virus-associated B-cell lymphoproliferative disorders: special references to lymphomas surrounding this newly recognized clinicopathologic disease. Cancer Sci. 2008;99(6):1085-1091. (Pubitemid 351676618)
3. Klein E, Kis LL, Klein G. Epstein-Barr virus infection in humans: from harmless to life endangering virus-lymphocyte interactions. Oncogene. 2007; 26(9):1297-1305. (Pubitemid 46328467)
4. Cohen JI, Kimura H, Nakamura S, Ko YH, Jaffe ES. Epstein-Barr virus-associated lymphoproliferative disease in non-immunocompromised hosts: a status report and summary of an international meeting, 8-9 September 2008. Ann Oncol. 2009; 20:1472-1482.
5. Swerdlow SH, Campo E, Harris NL, et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue. 4th ed. Lyon, France: IARC; 2008.
6. Oyama T, Yamamoto K, Asano N, et al. Age-related EBV-associated B-cell lymphoproliferative disorders constitute a distinct clinicopathologic group: a study of 96 patients. Clin Cancer Res. 2007;13(17):5124-5132. (Pubitemid 47502080)
7. Asano N, Yamamoto K, Tamaru J, et al. Age-related Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorders: comparison with EBVpositive classic Hodgkin lymphoma in elderly patients. Blood. 2009;113(12):2629-2636.
8. Hummel M, Anagnostopoulos I, Dallenbach F, Korbjuhn P, Dimmler C, Stein H. EBV infection patterns in Hodgkin's disease and normal lymphoid tissue: expression and cellular localization of EBV gene products. Br J Haematol. 1992; 82(4):689-694. (Pubitemid 23011974)
9. Niedobitek G, Herbst H, Young LS, et al. Patterns of Epstein-Barr virus infection in non-neoplastic lymphoid tissue. Blood. 1992;79(10):2520-2526.
10. Dojcinov SD, Venkataraman G, Raffeld M, Pittaluga S, Jaffe ES. EBV positive mucocutaneous ulcer: a study of 26 cases associated with various sources of immunosuppression. Am J Surg Pathol. 2010;34(3):405-417.
11. Oyama T, Ichimura K, Suzuki R, et al. Senile EBV+ B-cell lymphoproliferative disorders: a clinicopathologic study of 22 patients. Am J Surg Pathol. 2003;27(1):16-26. (Pubitemid 36014895)
12. Zu YL, Steinberg SM, Campo E, et al. Validation of tissue microarray immunohistochemistry staining and interpretation in diffuse large B-cell lymphoma. Leuk Lymphoma. 2005;46(5):693-701. (Pubitemid 40775217)
13. Martin-Subero JI, Gesk S, Harder L, Grote W, Siebert R. Interphase cytogenetics of hematologic neoplasms under the perspective of the novel WHO classification. Anticancer Res. 2003; 23(2A):1139-1148. (Pubitemid 36750931)
14. Ventura RA, Martin-Subero JI, Jones M, et al. FISH analysis for the detection of lymphoma-associated chromosomal abnormalities in routine paraffin-embedded tissue. J Mol Diagn. 2006; 8(2):141-151. (Pubitemid 43811236)
15. Poppe B, De Paepe P, Michaux L, et al. PAX5/ IGH rearrangement is a recurrent finding in a subset of aggressive B-NHL with complex chromosomal rearrangements. Genes Chromosomes Cancer. 2005;44(2):218-223. (Pubitemid 41306651)
16. Colomo L, Loong F, Rives S, et al. Diffuse large B-cell lymphomas with plasmablastic differentiation represent a heterogeneous group of disease entities. Am J Surg Pathol. 2004;28(6):736-747. (Pubitemid 38685887)
17. Ohno H, Nishikori M, Haga H, Isoda K. Epstein- Barr virus-positive diffuse large B-cell lymphoma carrying a t(9;14)(p13;q32) translocation. Int J Hematol. 2009;89(5):704-708.
18. Gibson SE, Hsi ED. Epstein-Barr virus-positive B-cell lymphoma of the elderly at a United States tertiary medical center: an uncommon aggressive lymphoma with a nongerminal center B-cell phenotype. Hum Pathol. 2009;40(5):653-661.
19. Kojima M, Sugiura I, Itoh H, et al. Histologic varieties of Epstein-Barr virus-related lymph node lesion resembling autoimmune disease-like clinicopathologic findings in middle-aged and elderly patients: a study of six cases. Pathol Res Pract. 2006;202(8):609-615. (Pubitemid 44057768)
20. Hjalgrim H, Askling J, Rostgaard K, et al. Characteristics of Hodgkin's lymphoma after infectious mononucleosis. N Engl J Med. 2003;349(14): 1324-1332. (Pubitemid 37186210)
21. Kapatai G, Murray P. Contribution of the Epstein Barr virus to the molecular pathogenesis of Hodgkin lymphoma. J Clin Pathol. 2007;60(12):1342- 1349. (Pubitemid 350252944)
22. Hakim FT, Gress RE. Immunosenescence: deficits in adaptive immunity in the elderly. Tissue Antigens. 2007;70(3):179-189. (Pubitemid 47106657)
23. Pawelec G, Larbi A. Immunity and ageing in man: annual review 2006/2007. Exp Gerontol. 2008; 43(1):34-38.
24. Sansoni P, Vescovini R, Fagnoni F, et al. The immune system in extreme longevity. Exp Gerontol. 2008;43(2):61-65.
25. Messaoudi I, Warner J, Nikolich-Zugich D, Fischer M, Nikolich-Zugich J. Molecular, cellular, and antigen requirements for development of age-associated T cell clonal expansions in vivo. J Immunol. 2006;176(1):301-308. (Pubitemid 43023275)
26. Ghia P, Prato G, Stella S, Scielzo C, Geuna M, Caligaris-Cappio F. Age-dependent accumulation of monoclonal CD4+CD8+ double positive T lymphocytes in the peripheral blood of the elderly. Br J Haematol. 2007;139(5):780-790. (Pubitemid 350115731)
27. Nakahara K, Utsunomiya A, Hanada S, et al. Transient appearance of CD3+CD8+ T lymphocytes with monoclonal gene rearrangement of T-cell receptor beta locus. Br J Haematol. 1998; 100(2):411-414.
28. Halvorsen JA, Brevig T, Aas T, Skar AG, Slevolden EM, Moi H. Genital ulcers as initial manifestation of Epstein-Barr virus infection: two new cases and a review of the literature. Acta Derm Venereol. 2006;86(5):439-442. (Pubitemid 44450102)
29. Knowles DM, Cesarman E, Chadburn A, et al. Correlative morphologic and molecular genetic analysis demonstrates three distinct categories of posttransplantation lymphoproliferative disorders. Blood. 1995;85(2):552-565.
30. Gibson KL, Wu YC, Barnett Y, et al. B-cell diversity decreases in old age and is correlated with poor health status. Aging Cell. 2009;8(1):18-25.
31. Heslop HE. Biology and treatment of Epstein-Barr virus-associated non-Hodgkin lymphomas. Hematology Am Soc Hematol Educ Program. 2005: 260-266.
32. Haque T, Wilkie GM, Jones MM, et al. Allogeneic cytotoxic T-cell therapy for EBV-positive posttransplantation lymphoproliferative disease: results of a phase 2 multicenter clinical trial. Blood. 2007;110(4):1123-1131. (Pubitemid 47281407)
33. Wilson WH, Kingma DW, Raffeld M, Wittes RE, Jaffe ES. Association of lymphomatoid granulomatosis with Epstein-Barr viral infection of B lymphocytes and response to inferon-alpha 2b. Blood. 1996;87(11):4531-4537. (Pubitemid 26162358)
34. Lim MS, Beaty M, Sorbara L, et al. T-cell/histiocyterich large B-cell lymphoma: a heterogeneous entity with derivation from germinal center B cells. Am J Surg Pathol. 2002;26(11):1458-1466. (Pubitemid 35239422)
35. Fraga M, Sanchez-Verde L, Forteza J, Garcia-Rivero A, Piris MA. T-cell/histiocyte-rich large B-cell lymphoma is a disseminated aggressive neoplasm: differential diagnosis from Hodgkin's lymphoma. Histopathology. 2002; 41(3):216-229. (Pubitemid 35013943)
36. Shiozawa E, Saito B, Yamochi-Onizuka T, et al. Senile EBV-associated B-cell lymphoproliferative disorder of indolent clinical phenotype with recurrence as aggressive lymphoma. Pathol Int. 2007; 57(10):688-693. (Pubitemid 47353045)
37. Kojima M, Morita Y, Nakamura N, Shimizu K, Murayama K, Nakamura S. Plasmacytic hyperplasia in age-related Epstein-Barr virus-associated lymphoproliferative disorders: a report of two cases. Pathol Res Pract. 2008;204(4):267-272.
38. Kamel OW, Weiss LM, van de Rijn M, Colby TV, Kingma DW, Jaffe ES. Hodgkin's disease and lymphoproliferations resembling Hodgkin's disease in patients receiving long-term low-dose methotrexate therapy. Am J Surg Pathol. 1996; 20(10):1279-1287. (Pubitemid 26336854)
39. Cavalli F. Rare syndromes in Hodgkin's disease. Ann Oncol. 1998;9(suppl 5):S109-S113. (Pubitemid 29049128)