Time correlated fluorescence characterization of an asymmetrically focused flow in a microfluidic device

Microfluidics and Nanofluidics

Volumn 10, Issue 3, 2011, Pages 551-561

  Carlotto, Silvia ^a   Fortunati, Ilaria ^a   Ferrante, Camilla ^a   Schwille, Petra ^b   Polimeno, Antonino ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Fluorescence correlation spectroscopy; Hydrodynamic focusing; Microfluidics; Navier Stokes equations

Indexed keywords

DIFFUSION IN LIQUIDS; FINITE ELEMENT METHOD; FLUIDIC DEVICES; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; MICROFLUIDICS; SPECTROSCOPIC ANALYSIS;

ASYMMETRIC FLOWS; CONCENTRATION PROFILES; CONVECTION-DIFFUSION EQUATIONS; FINITE-ELEMENT APPROACH; FLUORESCENCE CORRELATION SPECTROSCOPY; HYDRODYNAMIC FOCUSING; MICRO-FLUIDIC DEVICES; POSITION DETERMINATION;

NAVIER STOKES EQUATIONS;

EID: 79955948656     PISSN: 16134982     EISSN: 16134990     Source Type: Journal    
DOI: 10.1007/s10404-010-0689-x     Document Type: Article

References (56)

1. Bransky A, Korin N, Levenberg S (2008) Experimental and theoretical study of selective protein deposition using focused micro laminar flows. Biomed Microdevice 10:421-428
2. Brister PC, Kuricheti KK, Buschmann V, Weston KD (2005) Fluorescence correlation spectroscopy for flow rate imaging and monitoring-optimization, limitations and artifacts. Lab Chip 5:785-791 (Pubitemid 40980108)
3. Brody JP, Yager P, Goldstein RE, Austin RH (1996) Biotechnology at low Reynolds numbers. Biophys J 71:3430-3441 (Pubitemid 26422384)
4. Burstyn HC, Sengers JV (1983) Time dependence of critical concentration fluctuations in a binary liquid. Phys Rev A 27:1071-1085
5. Chang CC, Huang ZX, Yang RY (2007) Three-dimensional hydrodynamic focusing in two-layer polydimethylsiloxane (PDMS) microchannels. J Micromech Microeng 17:1479-1486
6. Chen CH, Cho SH, Tsai F, Erten A, Lo YH (2009) Microfluidic cell sorter with integrated piezoelectric actuator. Biomed Microdevices 11:1223-1231
7. Chung S, Park SJ, Kim JK, Chung C, Han DC, Chang JK (2003) Plastic microchip flow cytometer based on 2- and 3-dimensional hydrodynamic flow focusing. Microsystem Technol 9:525-533
8. Criswell KA, Bleavins MR, Zielinski D, Zandee JC, Walsh KM (1998) Flow cytometric evaluation of bone marrow differentials in rats with pharmacologically induced hematologic abnormalities. Cytometry 32:18-27 (Pubitemid 28222104)
9. Cubaud T, Mason TG (2008) Formation of miscible fluid microstructures by hydrodynamic focusing in plane geometries. Phys Rev E 78:056308
10. Darnton N, Bakajin O, Huang R, North B, Tegenfeldt JO, Cox EC, Sturm J, Austin RH (2001) Hydrodynamics in 2 1/2 dimensions: making jets in a plane. J Phys 13:4891-4902 (Pubitemid 32527849)
11. Deshpande A, Gua Y, Matthewsa S, Yunusa K, Slatera N, Brennanb C, Fishera A (2009) Hydrodynamic focusing studies in microreactors using voltammetric analysis: theory and experiment. Chem Eng J 49:428-434
12. Dittrich PS, Schwille P (2002) Spatial two-photon fluorescence crosscorrelation spectroscopy for controlling molecular transport in microfluidic structures. Anal Chem 74:4472-4479 (Pubitemid 35006436)
13. Dittrich PS, Schwille P (2003) An integrated microfluidic system for reaction, high-sensitivity detection, and sorting of fluorescent cells and particles. Anal Chem 75:5767-5774 (Pubitemid 37356457)
14. Domagalski PM, Mielnik MM, Lunde I, Saetran LR (2007) Characteristics of hydrodynamically focused streams for use in microscale particle image velocimetry (Micro-PIV). Heat Transf Eng 28:680-687 (Pubitemid 46897637)
15. Egawa T, Durand JL, Hayden EY, Rousseau DL, Yeh SR (2009) Design and evaluation of a passive alcove-based microfluidic mixer. Anal Chem 81:1622-1627
16. Elson EL, Magde D (1974) Fluorescence correlation spectroscopy I. Conceptual basics and theory. Biopolymers 13:1-27
17. Fenili D, Pirovano B (1998) The automation of sediment analysis using a new urine flow cytometer. Clin Chem Lab Med 36:909-917 (Pubitemid 29010100)
18. Ghosh M, Alves C, Tong Z, Tettey K, Konstantopoulos K, Stebe KJ (2008) Multifunctional surfaces with discrete functionalized regions for biological applications. Langmuir 24:8124-8142
19. Gosch M, Blom H, Holm J, Heino T, Rigler R (2000) Hydrodynamic flow profiling in microchannel structures by single molecule fluorescence correlation spectroscopy. Anal Chem 72:3260-3265 (Pubitemid 30482501)
20. Hertzog DE, Ivorra B, Mohammadi B, Bakajin O, Santiago JC (2006) Optimization of a microfluidic mixer for studying protein folding kinetics. Anal Chem 78:4299-4306
21. Kestin J, Sokolov M, Wakeham WA (1978) Viscosity of liquid water in the range -8°C to 150°C. J Phys Chem Ref Data 7:941-948 (Pubitemid 9407313)
22. Kim YR, Yee M, Metha S, Chupp V, Kendall R, Scott CS (1998) Simultaneous differentiation and quantitation of erythroblasts and white blood cells on a high throughput clinical haematology analyzer. Clin Lab Haematol 20:21-29 (Pubitemid 28179674)
23. Kohlheyer D, Besselink GAJ, Schlautmann S, Schasfoort BM (2006) Free-flow zone electrophoresis and isoelectric focusing using a microfabricated glass device with ion permeable membranes. Lab Chip 6:374-380 (Pubitemid 43327562)
24. Kunst BH, Schots A, Visser AJWG (2002) Detection of flowing fluorescent particles in a microcapillary using fluorescence correlation spectroscopy. Anal Chem 74:5350-5357 (Pubitemid 35215367)
25. Kuricheti KK, Buschmann V, Weston KD (2004a) Application of fluorescence correlation spectroscopy for velocity imaging in microfluidic devices. Appl Spectrosc 58:1180-1186
26. Kuricheti KK, Buschmann V, Brister P, Weston KD (2004b) Velocity imaging in microfluidic devices using fluorescence correlation spectroscopy. Microfluidics, BioMEMS, and medical microsystems II. Proc SPIE 5345:194-205
27. Lakowicz JR (2006) Principles of fluorescence, Chap 24, 3rd ed. Springer, New York.
28. Larsen MU, Shapley NC (2007) Stream spreading in multilayer microfluidic flows of suspensions. Anal Chem 79:1947-1953 (Pubitemid 46355226)
29. Lee GB, Hung CI, Ke BJ, Huang GR, Hwei RH, Lai HF (2001a) Freeflow zone electrophoresis and isoelectric focusing using a microfabricated glass device with ion permeable membranes. Trans ASME Chem 123:672-679
30. Lee GB, Hwei BH, Huang GR (2001b) Micromachined pre-focused M × N flow switches for continuous multi-sample injection. J Micromech Microeng 11:654-661
31. Lee GB, Chang CC, Huang SB, Yang RJ (2006) The hydrodynamic focusing effect inside rectangular microchannels. J Micromech Microeng 16:1024-1032
32. Lin CC, Chen A, Lin CH (2008) Microfluidic cell counter/sorter utilizing multiple particle tracing technique and optically switching approach. Biomed Microdevices 10:55-63
33. Liu C, Stakenborg T, Peeters S, Lagae L (2009) Cell manipulation with magnetic particles toward microfluidic cytometry. J Appl Phys 105:102014-1-102014-11
34. Magde D, Webb W, Elson E (1978) Fluorescence correlation spectroscopy III. Uniform translation and laminar flow. Biopolymers 17:361-376 (Pubitemid 8317012)
35. Mark D, Haeberle S, Roth G, von Stetten F, Zengerle R (2010) Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications. Chem Soc Rev 39:1153-1182
36. Mathur SR, Murthy JY (1997) Pressure boundary conditions for incompressible flow using unstructured meshes. Numer Heat Transf B 32:283-298 (Pubitemid 127574593)
37. Nguyen NT, Huang X (2005) Mixing in microchannels based on hydrodynamic focusing and time-interleaved segmentation: modelling and experiment. Lab Chip 5:1320-1326 (Pubitemid 41626191)
38. Nguyen NT, Yap YF, Sumargo A (2008) Microfluidic rheometer based on hydrodynamic focusing. Meas Sci Technol 19:085405- 1-085405-9
39. Pamme N, Wilhelm C (2006) Continuous sorting of magnetic cells via on-chip free-flow magnetophoresis. Lab Chip 6:974-980 (Pubitemid 44144207)
40. Park HY, Qiu X, Rhoades E, Korlach J, Kwok LW, Zipfel WR, Webb WW, Pollack L (2006) Achieving uniform mixing in a microfluidic device: hydrodynamic focusing prior to mixing. Anal Chem 78:4465-4473
41. Petrov EP, Schwille P (2008) Standardization and quality assurance in fluorescence measurements II: bioanalytical and biomedical applications. Springer series on fluorescence, vol 6, pp 145-197
42. Ren L, Sinton D, Li D (2003) Numerical simulation of microfluidic injection processes in crossing microchannels. J Micromech Microeng 13:739-747
43. Schwille P, Kummer S, Heikal AA, Moerner WE, Webb WW (2000) Fluorescence correlation spectroscopy reveals fast optical excitation- driven intramolecular dynamics of yellow fluorescent proteins. Proc Natl Acad Sci USA 97:151-156 (Pubitemid 30055799)
44. Simonnet C, Groisman A (2005) Two-dimensional hydrodynamic focusing in a simple microfluidic device. Appl Phys Lett 87:114104-1-114104-3
45. Sinton D (2004) Microscale flow visualization. Microfluid Nanofluid 1:2-21 (Pubitemid 41166498)
46. Song C, Nguyen NT, Tan SH, Asundi AK (2009) Modelling and optimization of micro optofluidic lenses. Lab Chip 9:1178-1184
47. Srisa-Art M, Bonzani IC, Williams A, Stevens MM, de Mello AJ, Edel JB (2009) Identification of rare progenitor cells from human periosteal tissue using droplet microfluidics. Analyst 134:2239-2245
48. Wang F, Wang H, Wang J, Wang HY, Rummel PL, Garimella SV, Lu C (2008) Microfluidic delivery of small molecules into mammalian cells based on hydrodynamic focusing. Biotechnol Bioeng 100:150-158 (Pubitemid 351579025)
49. Wereley ST, Meinhart CD (2010) Recent advances in micro-particle image velocimetry. Ann Rev Fluid Mech 42:557-576
50. Wong PK, Lee YK, Ho CM (2003) Deformation of DNA molecules by hydrodynamic focusing. J Fluid Mech 497:55-65 (Pubitemid 38171591)
51. Wu Z, Nguyen NT (2005) Hydrodynamic focusing in microchannels under consideration of diffusive dispersion: theories and experiments. Sens Actuators B 107:965-974 (Pubitemid 40655043)
52. Xuan X, Li D (2005) Focused electrophoretic motion and selected electrokinetic dispensing of particles and cells in cross-microchannels. Electrophoresis 26:3552-3560 (Pubitemid 41410378)
53. Yamada M, Seki M (2006) Microfluidic particle sorter employing flow splitting and recombining. Anal Chem 78:1357-1362 (Pubitemid 43271873)
54. Yang AS, Hsieh WH (2007) Hydrodynamic focusing investigation in a micro-flow cytometer. Biomed Microdev 9:113-122
55. Yeh HC, Puleo CM, Lim TC, Ho YP, Giza PE, Huang RC, Wang TH (2006) A Microfluidic-FCS platform for investigation on the dissociation of Sp1-DNA complex by doxorubicin. Nucl Acids Res 34:e144
56. Zhang Z, Zhao P, Xiao G, Lin M, Cao X (2008) Focusing-enhanced mixing in microfluidic channels. Biomicrofluidics 2:014101