Disproportionate HLA matching may contribute to racial disparity in patient survival following cardiac transplantation

Clinical Transplantation

Volumn 10, Issue 6 II, 1996, Pages 625-628

  Park, M H ^a   Tolman, D E ^a   Kimball, P M ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ethnic groups; Genes, MHC class I; Genes, MHC class II; Heart transplantation; Major histocompatibility complex; Survival rate

Indexed keywords

CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT;

ADULT; ARTICLE; CAUCASIAN; HEART TRANSPLANTATION; HLA MATCHING; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MAJOR CLINICAL STUDY; MALE; NEGRO; PRIORITY JOURNAL; RACE DIFFERENCE; RETROSPECTIVE STUDY; SURVIVAL; SURVIVAL RATE;

ACTUARIAL ANALYSIS; AFRICAN AMERICANS; AFRICAN CONTINENTAL ANCESTRY GROUP; AGE FACTORS; EUROPEAN CONTINENTAL ANCESTRY GROUP; HEART TRANSPLANTATION; HISTOCOMPATIBILITY TESTING; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TISSUE AND ORGAN PROCUREMENT;

EID: 0030467088     PISSN: 09020063     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. REED E, COHEN DJ. BARR ML. et al. Effect of recipient gender and race on heart and kidney allograft survival. Transpl Proc 1992: 24: 2670.
2. CECKA JM, GJERTSON DW, CHO Y, TERASAKI PI. HLA polymorphisms. ethnicity, and graft survival: United Network for Organ Sharing. Transpl Proc 1993: 25: 2446.
3. KERMAN RH, KIMBALL PM, VAN BUREN CT, LEWIS RM, KAHAN BD. Stronger immune responsiveness of blacks vs whites may account for renal allograft survival differences. Transpl Proc 1991: 23: 380
4. KOYAMA K, CECKA JM, TERASAKI PI. Kidney transplants in black recipients. Transplantation 1994: 57: 1064.
5. TERASAKI PI. Clinical Transplants 1990. The Regents of the University of California, 1991: p. 389.
6. KERMAN RH, KIMBALL P, SCHEINEN S, RADOVANCEVIC B, VAN BUREN CT, KAHAN BD, FRAZIER OH. The relationship among donor-recipient HLA mismatches, rejection, and death from coronary artery disease in cardiac transplant recipients. Transplantation 1994: 57: 884.
7. YACOUB M, FESTENSTEIN H, DOYLE P, et al. The influence of HLA matching in cardiac allograft recipients receiving cyclosporine and azathioprine. Transpl Proc 1987: 19: 2487
8. OPELZ G, WUJCIAK T. The influence of HLA compatibility on sraft survival after heart transplantation. N Engl J Med 1994: 330: 816.