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Volumn 13, Issue 3, 2011, Pages 208-214

Atherosclerosis: An epigenetic balancing act that goes wrong

Author keywords

Alternative splicing; Diet; Inflammation; Nuclear receptors

Indexed keywords

HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOID X RECEPTOR;

EID: 79955928265     PISSN: 15233804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11883-011-0174-3     Document Type: Review
Times cited : (35)

References (50)
  • 2
    • 46349101162 scopus 로고    scopus 로고
    • Characterizing the epidemiological transition inMexico: National and subnational burden of diseases, injuries, and risk factors
    • Stevens G, Dias RH, Thomas KJA, et al. Characterizing the epidemiological transition inMexico: national and subnational burden of diseases, injuries, and risk factors. PLoS Med. 2008;5:e125.
    • (2008) PLoS Med , vol.5
    • Stevens, G.1    Dias, R.H.2    Thomas, K.J.A.3
  • 3
    • 78049402859 scopus 로고    scopus 로고
    • Molecular signals of epigenetic states
    • Bonasio R, Tu S, Reinberg D. Molecular signals of epigenetic states. Science. 2010;330:612-6.
    • (2010) Science , vol.330 , pp. 612-616
    • Bonasio, R.1    Tu, S.2    Reinberg, D.3
  • 4
    • 77957339220 scopus 로고    scopus 로고
    • Interplay between different epigenetic modifications and mechanisms
    • Murr R. Interplay between different epigenetic modifications and mechanisms. Adv Genet. 2010;70:101-41.
    • (2010) Adv Genet , vol.70 , pp. 101-141
    • Murr, R.1
  • 5
    • 33847032960 scopus 로고    scopus 로고
    • The Mammalian Epigenome
    • DOI 10.1016/j.cell.2007.01.033, PII S0092867407001286
    • Berstein BE, Meissner A, Lander ES. The mammalian epigenome. Cell. 2007;128:669-81. (Pubitemid 46273573)
    • (2007) Cell , vol.128 , Issue.4 , pp. 669-681
    • Bernstein, B.E.1    Meissner, A.2    Lander, E.S.3
  • 6
    • 77957601692 scopus 로고    scopus 로고
    • Toll-like receptor-dependent lipid body formation in macrophage foam cell formation
    • Nicolaou G, Erridge C. Toll-like receptor-dependent lipid body formation in macrophage foam cell formation. Curr Opin Lipidol. 2010;21:427-33.
    • (2010) Curr Opin Lipidol , vol.21 , pp. 427-433
    • Nicolaou, G.1    Erridge, C.2
  • 7
    • 0032744380 scopus 로고    scopus 로고
    • Can reduced folic acid and vitamin B12 cause deficient DNA methylation producing mutations which initiate atherosclerosis?
    • Newman PE. Can reduced folic acid and vitamin B12 cause deficient DNA methylation producing mutations which initiate atherosclerosis? Med Hypotheses. 1999;53:421-4.
    • (1999) Med Hypotheses , vol.53 , pp. 421-424
    • Newman, P.E.1
  • 8
    • 33645869266 scopus 로고    scopus 로고
    • Folic acid, inflammation, and atherosclerosis: False hopes or the need for better trials?
    • Mangoni AA. Folic acid, inflammation, and atherosclerosis: false hopes or the need for better trials? Clin Chim Acta. 2006;367:11-9.
    • (2006) Clin Chim Acta , vol.367 , pp. 11-19
    • Mangoni, A.A.1
  • 13
    • 0022000776 scopus 로고
    • A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA
    • Bird A, Taggart M, Frommer M, Miller OJ, Macleod D. A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA. Cell. 1985;40:91-9.
    • (1985) Cell , vol.40 , pp. 91-99
    • Bird, A.1    Taggart, M.2    Frommer, M.3    Miller, O.J.4    Macleod, D.5
  • 14
    • 77953825565 scopus 로고    scopus 로고
    • DNA methylation as a biomarker for cardiovascular disease risk
    • KimM, Arakawa K,Wang R, et al. DNA methylation as a biomarker for cardiovascular disease risk. PLoS ONE. 2010;5:e9692.
    • (2010) PLoS ONE , vol.5
    • Kim, M.1    Arakawa, K.2    Wang, R.3
  • 16
    • 24644463193 scopus 로고    scopus 로고
    • Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis
    • DOI 10.1161/CIRCULATIONAHA.104.519025
    • Zhu S, Goldschmidt-Clermont PJ, Dong C. Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis. Circulation. 2005;112:1353-61. (Pubitemid 41266732)
    • (2005) Circulation , vol.112 , Issue.9 , pp. 1353-1361
    • Zhu, S.1    Goldschmidt-Clermont, P.J.2    Dong, C.3
  • 17
    • 37549027255 scopus 로고    scopus 로고
    • Hypermethylation of Fads2 and altered hepatic fatty acid and phospholipid metabolism in mice with hyperhomocysteinemia
    • Devlin AM, Singh R, Wade RE, et al. Hypermethylation of Fads2 and altered hepatic fatty acid and phospholipid metabolism in mice with hyperhomocysteinemia. J Biol Chem. 2007;282:37082-90.
    • (2007) J Biol Chem , vol.282 , pp. 37082-37090
    • Devlin, A.M.1    Singh, R.2    Wade, R.E.3
  • 18
    • 67349234989 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor-2 gene methylation is associated with low expression in carotid atherosclerotic plaques
    • Zawadzki C, Chatelain N, Delestre M, et al. Tissue factor pathway inhibitor-2 gene methylation is associated with low expression in carotid atherosclerotic plaques. Atherosclerosis. 2009;204:e4-14.
    • (2009) Atherosclerosis , vol.204
    • Zawadzki, C.1    Chatelain, N.2    Delestre, M.3
  • 19
    • 69149087790 scopus 로고    scopus 로고
    • Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density
    • This is the first direct demonstration that a pro-inflammatory fatty acid is capable of inducing global DNA methylation changes
    • Barrès R, Osler ME, Yan J, et al. Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. Cell Metab. 2009;10:189-98. This is the first direct demonstration that a pro-inflammatory fatty acid is capable of inducing global DNA methylation changes.
    • (2009) Cell Metab , vol.10 , pp. 189-198
    • Barrès, R.1    Osler, M.E.2    Yan, J.3
  • 20
    • 70449137733 scopus 로고
    • Role of dietary fat in human nutrition. I. Role of unsaturated dietary fat in infant nutrition
    • Hansen AE. Role of dietary fat in human nutrition. I. Role of unsaturated dietary fat in infant nutrition. Am J Public Health Nations Health. 1957;47:1367-70.
    • (1957) Am J Public Health Nations Health , vol.47 , pp. 1367-1370
    • Hansen, A.E.1
  • 21
    • 0043093697 scopus 로고    scopus 로고
    • Transposable elements: Targets for early nutritional effects on epigenetic gene regulation
    • DOI 10.1128/MCB.23.15.5293-5300.2003
    • Waterland RA, Jirtle RL. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. 2003;23:5293-300. (Pubitemid 36950884)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.15 , pp. 5293-5300
    • Waterland, R.A.1    Jirtle, R.L.2
  • 22
    • 77956866205 scopus 로고    scopus 로고
    • A Western-like fat diet is sufficient to induce a gradual enhancement in fat mass over generations
    • Massiera F, Barbry P, Guesnet P, et al. A Western-like fat diet is sufficient to induce a gradual enhancement in fat mass over generations. J Lipid Res. 2010;51:2352-61.
    • (2010) J Lipid Res , vol.51 , pp. 2352-2361
    • Massiera, F.1    Barbry, P.2    Guesnet, P.3
  • 23
    • 78649955848 scopus 로고    scopus 로고
    • The honey bee epigenomes: Differential methylation of brain DNA in queens and workers
    • This is a genome-wide analysis of diet-specific DNA methylation patterns in honeybees. Intragenic sequences represent a significant portion of differentially methylated sequences, which is likely to underlie differential transcript splicing profiles
    • Lycko F, Foret S, Kucharski R, et al. The honey bee epigenomes: differential methylation of brain DNA in queens and workers. PLoS Biol. 2010;8:e1000506. This is a genome-wide analysis of diet-specific DNA methylation patterns in honeybees. Intragenic sequences represent a significant portion of differentially methylated sequences, which is likely to underlie differential transcript splicing profiles.
    • (2010) PLoS Biol , vol.8
    • Lycko, F.1    Foret, S.2    Kucharski, R.3
  • 24
    • 41349085806 scopus 로고    scopus 로고
    • Nutritional control of reproductive status in honeybees via DNA methylation
    • This article is a demonstration that a differential dietary regime is associated with specific DNA methylation patterns
    • Kucharski R, Maleszka J, Foret S, Maleszka R. Nutritional control of reproductive status in honeybees via DNA methylation. Science. 2008;319:1827-30. This article is a demonstration that a differential dietary regime is associated with specific DNA methylation patterns.
    • (2008) Science , vol.319 , pp. 1827-1830
    • Kucharski, R.1    Maleszka, J.2    Foret, S.3    Maleszka, R.4
  • 25
    • 17544371811 scopus 로고    scopus 로고
    • Alternative splicing of the human cholesteryl ester transfer protein gene in transgenic mice: Exon exclusion modulates gene expression in response to dietary or developmental change
    • DOI 10.1074/jbc.271.21.12603
    • Yang TP, Agellon LB, Walsh A, Breslow JL, Tall AR. Alternative splicing of the human cholesteryl ester transfer protein gene in transgenic mice. Exon exclusion modulates gene expression in response to dietary or developmental change. J Biol Chem. 1996;271:12603-9. (Pubitemid 26160935)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.21 , pp. 12603-12609
    • Yang, T.-P.1    Agellon, L.B.2    Walsh, A.3    Breslow, J.L.4    Tall, A.R.5
  • 27
    • 77955627637 scopus 로고    scopus 로고
    • Nutrition, epigenetics, and developmental plasticity: Implications for understanding human disease
    • Burdge GC, Lillycrop KA. Nutrition, epigenetics, and developmental plasticity: implications for understanding human disease. Annu Rev Nutr. 2010;30:315-39.
    • (2010) Annu Rev Nutr , vol.30 , pp. 315-339
    • Burdge, G.C.1    Lillycrop, K.A.2
  • 28
    • 64549141177 scopus 로고    scopus 로고
    • Adult onset atherosclerosis may have its origin in the foetal state in utero
    • Mukherjee S. Adult onset atherosclerosis may have its origin in the foetal state in utero. Curr Opin Lipidol. 2009;20:155-6.
    • (2009) Curr Opin Lipidol , vol.20 , pp. 155-156
    • Mukherjee, S.1
  • 29
    • 77955170550 scopus 로고    scopus 로고
    • Nuclear receptors and inflammation control: Molecular mechanisms and pathophysiological relevance
    • Huang W, Glass CK. Nuclear receptors and inflammation control: molecular mechanisms and pathophysiological relevance. Arterioscler Thromb Vasc Biol. 2010;30:1542-9.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1542-1549
    • Huang, W.1    Glass, C.K.2
  • 33
    • 65949105277 scopus 로고    scopus 로고
    • PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients
    • Regieli JJ, Jukema JW, Doevendans PA, et al. PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients. Diab Care. 2009;32:839-44.
    • (2009) Diab Care , vol.32 , pp. 839-844
    • Regieli, J.J.1    Jukema, J.W.2    Doevendans, P.A.3
  • 34
    • 61749083559 scopus 로고    scopus 로고
    • PPARgamma in the endothelium regulates metabolic responses to high-fat diet in mice
    • Kanda T, Brown JD, Orasanu G, et al. PPARgamma in the endothelium regulates metabolic responses to high-fat diet in mice. J Clin Invest. 2009;119:110-24.
    • (2009) J Clin Invest , vol.119 , pp. 110-124
    • Kanda, T.1    Brown, J.D.2    Orasanu, G.3
  • 35
    • 78650317248 scopus 로고    scopus 로고
    • Endogenous ligands for nuclear receptors: Digging deeper
    • Oct 18, Epub ahead of print
    • Schupp M, Lazar MA. Endogenous ligands for nuclear receptors: digging deeper. J Biol Chem. 2010 Oct 18, [Epub ahead of print].
    • (2010) J Biol Chem
    • Schupp, M.1    Lazar, M.A.2
  • 36
    • 0030828307 scopus 로고    scopus 로고
    • Constitutive activation of NF-kappaB in an animal model of aging
    • DOI 10.1093/intimm/9.10.1581
    • Spencer NF, Poynter ME, Im SY, Daynes RA. Constitutive activation of NF-kappa B in an animal model of aging. Int Immunol. 1997;9:1581-8. (Pubitemid 27434691)
    • (1997) International Immunology , vol.9 , Issue.10 , pp. 1581-1588
    • Spencer, N.F.L.1    Poynter, M.E.2    Im, S.-Y.3    Daynes, R.A.4
  • 37
    • 78149449130 scopus 로고    scopus 로고
    • ApoE-/- PGC-1α-/- mice display reduced IL-18 levels and do not develop enhanced atherosclerosis
    • This is a demonstration of the dual activity of PPARs. Co-activator PPAR partners can exert pro-inflammatory effects in addition to the well-established repressive activity of PPARs on NF-κB and other inflammation markers
    • Stein S, Lohmann C, Handschin C, et al. ApoE-/- PGC-1α-/- mice display reduced IL-18 levels and do not develop enhanced atherosclerosis. PLoS One. 2010;5:13539. This is a demonstration of the dual activity of PPARs. Co-activator PPAR partners can exert pro-inflammatory effects in addition to the well-established repressive activity of PPARs on NF-κB and other inflammation markers.
    • (2010) PLoS One , vol.5 , pp. 13539
    • Stein, S.1    Lohmann, C.2    Handschin, C.3
  • 38
    • 77951737083 scopus 로고    scopus 로고
    • Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor gamma activation
    • Zhang Y, Luo Z, Ma L, et al. Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor gamma activation. Int J Mol Med. 2010;25:729-34.
    • (2010) Int J Mol Med , vol.25 , pp. 729-734
    • Zhang, Y.1    Luo, Z.2    Ma, L.3
  • 39
    • 77953374504 scopus 로고    scopus 로고
    • The fat-1 transgene in mice increases antioxidant potential, reduces proinflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet
    • Rahman M, Halade GV, Bhattacharya A, Fernandes G. The fat-1 transgene in mice increases antioxidant potential, reduces proinflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. Oxid Med Cell Longev. 2009;2:307-16.
    • (2009) Oxid Med Cell Longev , vol.2 , pp. 307-316
    • Rahman, M.1    Halade, G.V.2    Bhattacharya, A.3    Fernandes, G.4
  • 40
    • 69849111863 scopus 로고    scopus 로고
    • Activation of NFkappaB by palmitate in endothelial cells: A key role for NADPH oxidase-derived superoxide in response to TLR4 activation
    • Maloney E, Sweet IR, Hockenbery DM, et al. Activation of NFkappaB by palmitate in endothelial cells: a key role for NADPH oxidase-derived superoxide in response to TLR4 activation. Arterioscler Thromb Vasc Biol. 2009;29:1370-5.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1370-1375
    • Maloney, E.1    Sweet, I.R.2    Hockenbery, D.M.3
  • 41
    • 74949127867 scopus 로고    scopus 로고
    • Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cells
    • This is a demonstration that distinct fatty acids differentially regulate inflammation by activating specific and cross-talking pathways involving PPARs and TLR, respectively
    • Coll T, Palomer X, Blanco-Vaca F, et al. Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cells. Endocrinology. 2010;151:537-48. This is a demonstration that distinct fatty acids differentially regulate inflammation by activating specific and cross-talking pathways involving PPARs and TLR, respectively.
    • (2010) Endocrinology , vol.151 , pp. 537-548
    • Coll, T.1    Palomer, X.2    Blanco-Vaca, F.3
  • 42
    • 77954570636 scopus 로고    scopus 로고
    • Leukotriene B4 is a physiologically relevant endogenous peroxisome proliferatoractivated receptor-alpha agonist
    • Narala VR, Adapala RK, Suresh MV, et al. Leukotriene B4 is a physiologically relevant endogenous peroxisome proliferatoractivated receptor-alpha agonist. J Biol Chem. 2010;285:22067-74.
    • (2010) J Biol Chem , vol.285 , pp. 22067-22074
    • Narala, V.R.1    Adapala, R.K.2    Suresh, M.V.3
  • 43
    • 79955913722 scopus 로고    scopus 로고
    • De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis
    • This is an exhaustive mapping of PPAR binding site across the genome
    • Hamza MS, Pott S, Vega VB, et al. De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis. Genes Dev. 2008;22:2953-67. This is an exhaustive mapping of PPAR binding site across the genome.
    • (2008) Genes Dev , vol.22 , pp. 2953-2967
    • Hamza, M.S.1    Pott, S.2    Vega, V.B.3
  • 44
    • 79955923292 scopus 로고    scopus 로고
    • Genome-wide profiling of PPARgamma: RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
    • This is an exhaustive mapping of PPAR binding site across the genome, with additional focus on promoter targets
    • Nielsen, R, Pedersen TA, Hagenbeek D, et al. Genome-wide profiling of PPARgamma: RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. PLoS. 2010;5:e13539. This is an exhaustive mapping of PPAR binding site across the genome, with additional focus on promoter targets.
    • (2010) PLoS , vol.5
    • Nielsen, R.1    Pedersen, T.A.2    Hagenbeek, D.3
  • 45
    • 77954171220 scopus 로고    scopus 로고
    • Contrasting chromatin organization of CpG islands and exons in the human genome
    • Choi JK. Contrasting chromatin organization of CpG islands and exons in the human genome. Genome Biol. 2010;11:R70.
    • (2010) Genome Biol , vol.11
    • Choi, J.K.1
  • 46
    • 77957174102 scopus 로고    scopus 로고
    • Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated
    • Choy MK, Movassagh M, Goh HG, et al. Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated. BMC Genomics. 2010;11:519.
    • (2010) BMC Genomics , vol.11 , pp. 519
    • Choy, M.K.1    Movassagh, M.2    Goh, H.G.3
  • 48
    • 0025690662 scopus 로고
    • Mechanisms for the construction and developmental control of heterochromatin formation and imprinted chromosome domains
    • Tartof KD, Bremer M. Mechanisms for the construction and developmental control of heterochromatin formation and imprinted chromosome domains. Dev Suppl. 1990;35-45.
    • (1990) Dev Suppl , pp. 35-45
    • Tartof, K.D.1    Bremer, M.2
  • 49
    • 69349098474 scopus 로고    scopus 로고
    • Epigenetics: Definition, mechanisms and clinical perspective
    • Dupont C, Armant DR, Brenner CA. Epigenetics: definition, mechanisms and clinical perspective. Semin Reprod Med. 2009;27:351-7.
    • (2009) Semin Reprod Med , vol.27 , pp. 351-357
    • Dupont, C.1    Armant, D.R.2    Brenner, C.A.3
  • 50
    • 46249117780 scopus 로고    scopus 로고
    • Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation
    • Kerkel K, Spadola A, Yuan E, et al. Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation. Nat Genet. 2008;40:904-8.
    • (2008) Nat Genet , vol.40 , pp. 904-908
    • Kerkel, K.1    Spadola, A.2    Yuan, E.3


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