Cellular immune response in hepatitis C infection: Role of CD154 expression and clinical relevance;Zelluläre Immunantwort bei der Hepatitis-C-Virusinfektion: Rolle und klinische Relevanz der CD154-Expression

Deutsche Medizinische Wochenschrift

Volumn 136, Issue 20, 2011, Pages 1073-1077

  Muller M ^a   Blum, H E ^a   Er, F ^b   Thimme, R ^a   Semmo, N ^a,c  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

CD154 (CD40 ligand) expression; hepatitis C Virus (HCV); human immunodeficiency virus (HIV)

Indexed keywords

CD40 LIGAND; VIRUS ANTIGEN;

CD4+ T LYMPHOCYTE; CELL FUNCTION; CELLULAR IMMUNITY; HEPATITIS C; HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PROTEIN EXPRESSION; REVIEW; VIRAL CLEARANCE;

EID: 79955903047     PISSN: 00120472     EISSN: 14394413     Source Type: Journal    
DOI: 10.1055/s-0031-1275846     Document Type: Review

References (8)

1. Chattopadhyay P K., Yu J, Roederer M. A live-cell assay to detect antigen-specific CD4+ T cells with diverse cytokine profiles. Nature Medicine 2005 10 1113-17 (Pubitemid 41486835)
2. Ford G S., Barnhart B, Shone S et al,. Regulation of CD154 (CD40 ligand) mRNA stability during T cell activation. J Immunol 1999 162 4037-44 (Pubitemid 29314786)
3. Frentsch M, Arbach O, Kirchhoff D et al,. Direct access to CD4+ T cells specific for defined antigens according to CD154 expression. Nature Medicine 2005 11 1118-24 (Pubitemid 41486836)
4. Mueller M, Spangenberg H C., Kersting N et al,. Virus-specific CD4+ T cell responses in chronic HCV infection in blood and liver identified by antigen-specific upregulation of CD154. J Hepatol 2010 52 800-11
5. Phipps R P., Koumas L, Leung E et al,. The CD40-CD40 ligand system: a potential therapeutic target in atherosclerosis. Curr Opin Investig Drugs 2001 2 773-777 (Pubitemid 32936669)
6. Roy M, Aruffo A, Ledbetter J et al,. Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses. Eur J Immunol 1995 25 596-603
7. Srahna M, Remacle J E., Annamalai K et al,. NF-(B is involved in the regulation of CD154 (CD40 ligand) expression in primary human T cells. Clin Exp Immunol 2001 125 229-236 (Pubitemid 32758433)
8. Subauste C S., Wessendarp M, Portilllo J A. et al,. Pathogen-specific induction of CD154 is impaired in CD4+ T cells from human immunodeficiency virus-infected patients. J Infect Dis 2004 189 61-70 (Pubitemid 38122330)