-
1
-
-
59749095425
-
Pleiotropic functional properties of androgen receptor mutants in prostate cancer
-
Bergerat JP, Ceraline J: Pleiotropic functional properties of androgen receptor mutants in prostate cancer. Hum Mutat 2009; 30: 145-157.
-
(2009)
Hum Mutat
, vol.30
, pp. 145-157
-
-
Bergerat, J.P.1
Ceraline, J.2
-
2
-
-
0036682002
-
Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease
-
LaTulippe E, Satagopan J, Smith A, Scher H, Scardino P, Reuter V, Gerald WL: Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease. Cancer Res 2002; 62: 4499-4506. (Pubitemid 34827314)
-
(2002)
Cancer Research
, vol.62
, Issue.15
, pp. 4499-4506
-
-
LaTulippe, E.1
Satagopan, J.2
Smith, A.3
Scher, H.4
Scardino, P.5
Reuter, V.6
Gerald, W.L.7
-
3
-
-
0042978480
-
Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer
-
DOI 10.1038/sj.bjc.6601127
-
Edwards J, Krishna NS, Grigor KM, Bartlett JM: Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer. Br J Cancer 2003; 89: 552-556. (Pubitemid 37026442)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.3
, pp. 552-556
-
-
Edwards, J.1
Krishna, N.S.2
Grigor, K.M.3
Bartlett, J.M.S.4
-
4
-
-
74049109753
-
Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22rv1 hormone-refractory prostate cancer (PCA) cell line
-
Marcias G, Erdmann E, Lapouge G, Siebert C, Barthelemy P, Duclos B, Bergerat JP, Ceraline J, Kurtz JE: Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22rv1 hormone-refractory prostate cancer (PCA) cell line. Hum Mutat 2010; 31: 74-80.
-
(2010)
Hum Mutat
, vol.31
, pp. 74-80
-
-
Marcias, G.1
Erdmann, E.2
Lapouge, G.3
Siebert, C.4
Barthelemy, P.5
Duclos, B.6
Bergerat, J.P.7
Ceraline, J.8
Kurtz, J.E.9
-
5
-
-
43449094647
-
Mechanisms of androgen receptor activation in advanced prostate cancer: Differential co-activator recruitment and gene expression
-
DOI 10.1038/sj.onc.1210955, PII 1210955
-
Brooke GN, Parker MG, Bevan CL: Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression. Oncogene 2008; 27: 2941-2950. (Pubitemid 351668003)
-
(2008)
Oncogene
, vol.27
, Issue.21
, pp. 2941-2950
-
-
Brooke, G.N.1
Parker, M.G.2
Bevan, C.L.3
-
6
-
-
0027203411
-
Flutamide withdrawal syndrome: Its impact on clinical trials in hormone- refractory prostate cancer
-
Scher HI, Kelly WK: Flutamide withdrawal syndrome: its impact on clinical trials in hormone-refractory prostate cancer. J Clin Oncol 1993; 11: 1566-1572. (Pubitemid 23228264)
-
(1993)
Journal of Clinical Oncology
, vol.11
, Issue.8
, pp. 1566-1572
-
-
Scher, H.I.1
Kelly, W.K.2
-
7
-
-
65649090203
-
Development of a second-generation antiandrogen for treatment of advanced prostate cancer
-
Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL: Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 2009; 324: 787-790.
-
(2009)
Science
, vol.324
, pp. 787-790
-
-
Tran, C.1
Ouk, S.2
Clegg, N.J.3
Chen, Y.4
Watson, P.A.5
Arora, V.6
Wongvipat, J.7
Smith-Jones, P.M.8
Yoo, D.9
Kwon, A.10
Wasielewska, T.11
Welsbie, D.12
Chen, C.D.13
Higano, C.S.14
Beer, T.M.15
Hung, D.T.16
Scher, H.I.17
Jung, M.E.18
Sawyers, C.L.19
-
8
-
-
77952105685
-
Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study
-
Scher HI, Beer TM, Higano CS, Anand A, Taplin ME, Efstathiou E, Rathkopf D, Shelkey J, Yu EY, Alumkal J, Hung D, Hirmand M, Seely L, Morris MJ, Danila DC, Humm J, Larson S, Fleisher M, Sawyers CL: Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study. Lancet 2010; 375: 1437-1446.
-
(2010)
Lancet
, vol.375
, pp. 1437-1446
-
-
Scher, H.I.1
Beer, T.M.2
Higano, C.S.3
Anand, A.4
Taplin, M.E.5
Efstathiou, E.6
Rathkopf, D.7
Shelkey, J.8
Yu, E.Y.9
Alumkal, J.10
Hung, D.11
Hirmand, M.12
Seely, L.13
Morris, M.J.14
Danila, D.C.15
Humm, J.16
Larson, S.17
Fleisher, M.18
Sawyers, C.L.19
-
10
-
-
65549113046
-
Ketoconazole retains activity in patients with docetaxel-refractory prostate cancer
-
Galsky MD, Simon K, Sonpavde G, Hutson TE, Fleming M, Kondagunta GV, Berry W: Ketoconazole retains activity in patients with docetaxel-refractory prostate cancer. Ann Oncol 2009; 20: 965-966.
-
(2009)
Ann Oncol
, vol.20
, pp. 965-966
-
-
Galsky, M.D.1
Simon, K.2
Sonpavde, G.3
Hutson, T.E.4
Fleming, M.5
Kondagunta, G.V.6
Berry, W.7
-
11
-
-
3042784503
-
17,20-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer
-
O'Donnell A, Judson I, Dowsett M, Raynaud F, Dearnaley D, Mason M, Harland S, Robbins A, Halbert G, Nutley B, Jarman M: Hormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (cb7630) in patients with prostate cancer. Br J Cancer 2004; 90: 2317-2325. (Pubitemid 38961894)
-
(2004)
British Journal of Cancer
, vol.90
, Issue.12
, pp. 2317-2325
-
-
O'Donnell, A.1
Judson, I.2
Dowsett, M.3
Raynaud, F.4
Dearnaley, D.5
Mason, M.6
Harland, S.7
Robbins, A.8
Halbert, G.9
Nutley, B.10
Jarman, M.11
-
12
-
-
53749090666
-
Phase i clinical trial of a selective inhibitor of cyp17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven
-
Attard G, Reid AH, Yap TA, Raynaud F, Dowsett M, Settatree S, Barrett M, Parker C, Martins V, Folkerd E, Clark J, Cooper CS, Kaye SB, Dearnaley D, Lee G, de Bono JS: Phase I clinical trial of a selective inhibitor of cyp17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. J Clin Oncol 2008; 26: 4563-4571.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4563-4571
-
-
Attard, G.1
Reid, A.H.2
Yap, T.A.3
Raynaud, F.4
Dowsett, M.5
Settatree, S.6
Barrett, M.7
Parker, C.8
Martins, V.9
Folkerd, E.10
Clark, J.11
Cooper, C.S.12
Kaye, S.B.13
Dearnaley, D.14
Lee, G.15
De Bono, J.S.16
-
13
-
-
68949094223
-
Selective inhibition of cyp17 with abiraterone acetate is highly active in the treatment of castrationresistant prostate cancer
-
Attard G, Reid AH, A'Hern R, Parker C, Oommen NB, Folkerd E, Messiou C, Molife LR, Maier G, Thompson E, Olmos D, Sinha R, Lee G, Dowsett M, Kaye SB, Dearnaley D, Kheoh T, Molina A, de Bono JS: Selective inhibition of cyp17 with abiraterone acetate is highly active in the treatment of castrationresistant prostate cancer. J Clin Oncol 2009; 27: 3742-3748.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3742-3748
-
-
Attard, G.1
Reid, A.H.2
A'Hern, R.3
Parker, C.4
Oommen, N.B.5
Folkerd, E.6
Messiou, C.7
Molife, L.R.8
Maier, G.9
Thompson, E.10
Olmos, D.11
Sinha, R.12
Lee, G.13
Dowsett, M.14
Kaye, S.B.15
Dearnaley, D.16
Kheoh, T.17
Molina, A.18
De Bono, J.S.19
-
14
-
-
77951591066
-
Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer
-
Danila DC, Morris MJ, de Bono JS, Ryan CJ, Denmeade SR, Smith MR, Taplin ME, Bubley GJ, Kheoh T, Haqq C, Molina A, Anand A, Koscuiszka M, Larson SM, Schwartz LH, Fleisher M, Scher HI: Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer. J Clin Oncol 2010; 28: 1496-1501.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1496-1501
-
-
Danila, D.C.1
Morris, M.J.2
De Bono, J.S.3
Ryan, C.J.4
Denmeade, S.R.5
Smith, M.R.6
Taplin, M.E.7
Bubley, G.J.8
Kheoh, T.9
Haqq, C.10
Molina, A.11
Anand, A.12
Koscuiszka, M.13
Larson, S.M.14
Schwartz, L.H.15
Fleisher, M.16
Scher, H.I.17
-
15
-
-
79956373056
-
Bone scan 'flare' in patients receiving abiraterone acetate (Aa) for metastatic castration resistant prostate cancer (MCRPC): Analysis of data from a phase II study of the Department of Defense Prostate Cancer Clinical Trials Consortium (abstract)
-
Shah S, Ryan C, Kilian C, Hubbell A, Kheoh T, Haqq C, Molina A, Small E: Bone scan 'flare' in patients receiving abiraterone acetate (Aa) for metastatic castration resistant prostate cancer (MCRPC): analysis of data from a phase II study of the Department of Defense Prostate Cancer Clinical Trials Consortium (abstract). J Clin Oncol 2010; 28(15s):4545.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15 S
, pp. 4545
-
-
Shah, S.1
Ryan, C.2
Kilian, C.3
Hubbell, A.4
Kheoh, T.5
Haqq, C.6
Molina, A.7
Small, E.8
-
16
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
DOI 10.1056/NEJMoa040720
-
Tannock IF, de Wit R, Berry WR, Horti J, Pluzanska A, Chi KN, Oudard S, Theodore C, James ND, Turesson I, Rosenthal MA, Eisenberger MA: Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 2004; 351: 1502-1512. (Pubitemid 39315317)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.15
, pp. 1502-1512
-
-
Tannock, I.F.1
De Wit, R.2
Berry, W.R.3
Horti, J.4
Pluzanska, A.5
Chi, K.N.6
Oudard, S.7
Theodore, C.8
James, N.D.9
Turesson, I.10
Rosenthal, M.A.11
Eisenberger, M.A.12
-
17
-
-
38349167518
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: Updated survival in the tax 327 study
-
Berthold DR, Pond GR, Soban F, de Wit R, Eisenberger M, Tannock IF: Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the tax 327 study. J Clin Oncol 2008; 26: 242-245.
-
(2008)
J Clin Oncol
, vol.26
, pp. 242-245
-
-
Berthold, D.R.1
Pond, G.R.2
Soban, F.3
De Wit, R.4
Eisenberger, M.5
Tannock, I.F.6
-
18
-
-
35448959580
-
Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: A meta-analysis of individual patient data
-
DOI 10.1016/S1470-2045(07)70284-X, PII S147020450770284X
-
Fizazi K, Le Maitre A, Hudes G, Berry WR, Kelly WK, Eymard JC, Logothetis CJ, Pignon JP, Michiels S: Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: a meta-analysis of individual patient data. Lancet Oncol 2007; 8: 994-1000. (Pubitemid 47629887)
-
(2007)
Lancet Oncology
, vol.8
, Issue.11
, pp. 994-1000
-
-
Fizazi, K.1
Le Maitre, A.2
Hudes, G.3
Berry, W.R.4
Kelly, W.K.5
Eymard, J.-C.6
Logothetis, C.J.7
Pignon, J.-P.8
Michiels, S.9
-
19
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
DOI 10.1056/NEJMoa041318
-
Petrylak DP, Tangen CM, Hussain MH, Lara PN, Jr., Jones JA, Taplin ME, Burch PA, Berry D, Moinpour C, Kohli M, Benson MC, Small EJ, Raghavan D, Crawford ED: Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 2004; 351: 1513-1520. (Pubitemid 39315318)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.15
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.A.3
Lara Jr., P.N.4
Jones, J.A.5
Taplin, M.E.6
Burch, P.A.7
Berry, D.8
Moinpour, C.9
Kohli, M.10
Benson, M.C.11
Small, E.J.12
Raghavan, D.13
Crawford, E.D.14
-
20
-
-
77956556274
-
Docetaxel reintroduction in patients with metastatic castration-resistant docetaxel-sensitive prostate cancer: A retrospective multicentre study
-
Eymard JC, Oudard S, Gravis G, Ferrero JM, Theodore C, Joly F, Priou F, Krakowski I, Zannetti A, Thill L, Beuzeboc P: Docetaxel reintroduction in patients with metastatic castration-resistant docetaxel-sensitive prostate cancer: a retrospective multicentre study. BJU Int 2010; 106: 974-978.
-
(2010)
BJU Int
, vol.106
, pp. 974-978
-
-
Eymard, J.C.1
Oudard, S.2
Gravis, G.3
Ferrero, J.M.4
Theodore, C.5
Joly, F.6
Priou, F.7
Krakowski, I.8
Zannetti, A.9
Thill, L.10
Beuzeboc, P.11
-
21
-
-
54949154102
-
Docetaxel chemotherapy for metastatic hormone refractory prostate cancer as first-line palliative chemotherapy and subsequent re-treatment: Birmingham experience
-
Ansari J, Hussain SA, Zarkar A, Tanguay JS, Bliss J, Glaholm J: Docetaxel chemotherapy for metastatic hormone refractory prostate cancer as first-line palliative chemotherapy and subsequent re-treatment: Birmingham experience. Oncol Rep 2008; 20: 891-896.
-
(2008)
Oncol Rep
, vol.20
, pp. 891-896
-
-
Ansari, J.1
Hussain, S.A.2
Zarkar, A.3
Tanguay, J.S.4
Bliss, J.5
Glaholm, J.6
-
22
-
-
53049088662
-
Survival and psa response of patients in the tax 327 study who crossed over to receive docetaxel after mitoxantrone or vice versa
-
Berthold DR, Pond GR, de Wit R, Eisenberger M, Tannock IF: Survival and psa response of patients in the tax 327 study who crossed over to receive docetaxel after mitoxantrone or vice versa. Ann Oncol 2008; 19: 1749-1753.
-
(2008)
Ann Oncol
, vol.19
, pp. 1749-1753
-
-
Berthold, D.R.1
Pond, G.R.2
De Wit, R.3
Eisenberger, M.4
Tannock, I.F.5
-
23
-
-
77249176173
-
Estramustine plus docetaxel as second-line therapy in patients with hormone-refractory prostate cancer resistant to docetaxel alone
-
Caffo O, Sava T, Comploj E, Giampaolo MA, Segati R, Valduga F, Cetto G, Galligioni E: Estramustine plus docetaxel as second-line therapy in patients with hormone-refractory prostate cancer resistant to docetaxel alone. Urol Oncol 2010; 28: 152-156.
-
(2010)
Urol Oncol
, vol.28
, pp. 152-156
-
-
Caffo, O.1
Sava, T.2
Comploj, E.3
Giampaolo, M.A.4
Segati, R.5
Valduga, F.6
Cetto, G.7
Galligioni, E.8
-
24
-
-
59449102526
-
Phase i and pharmacokinetic study of xrp6258 (rpr 116258a), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors
-
Mita AC, Denis LJ, Rowinsky EK, Debono JS, Goetz AD, Ochoa L, Forouzesh B, Beeram M, Patnaik A, Molpus K, Semiond D, Besenval M, Tolcher AW: Phase I and pharmacokinetic study of xrp6258 (rpr 116258a), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors. Clin Cancer Res 2009; 15: 723-730.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 723-730
-
-
Mita, A.C.1
Denis, L.J.2
Rowinsky, E.K.3
Debono, J.S.4
Goetz, A.D.5
Ochoa, L.6
Forouzesh, B.7
Beeram, M.8
Patnaik, A.9
Molpus, K.10
Semiond, D.11
Besenval, M.12
Tolcher, A.W.13
-
25
-
-
50849088935
-
A multicenter phase ii study of xrp6258 administered as a 1-h i.v. infusion every 3 weeks in taxane-resistant metastatic breast cancer patients
-
Pivot X, Koralewski P, Hidalgo JL, Chan A, Goncalves A, Schwartsmann G, Assadourian S, Lotz JP: A multicenter phase ii study of xrp6258 administered as a 1-h i.v. infusion every 3 weeks in taxane-resistant metastatic breast cancer patients. Ann Oncol 2008; 19: 1547-1552.
-
(2008)
Ann Oncol
, vol.19
, pp. 1547-1552
-
-
Pivot, X.1
Koralewski, P.2
Hidalgo, J.L.3
Chan, A.4
Goncalves, A.5
Schwartsmann, G.6
Assadourian, S.7
Lotz, J.P.8
-
26
-
-
77956542827
-
Cabazitaxel or mitoxantrone with prednisone in patients with metastatic castration-resistant prostate cancer (MCRPC) previously treated with docetaxel: Final results of a multinational phase III trial (tropic) (abstract)
-
TROPIC Investigators
-
Sartor SO, Ozguroglu M, Hansen S, Machiels JH, Shen L, Gupta S, De Bono JS, TROPIC Investigators: Cabazitaxel or mitoxantrone with prednisone in patients with metastatic castration-resistant prostate cancer (MCRPC) previously treated with docetaxel: final results of a multinational phase III trial (tropic) (abstract). J Clin Oncol 2010; 28(15s): 4508.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15 S
, pp. 4508
-
-
Sartor, S.O.1
Ozguroglu, M.2
Hansen, S.3
MacHiels, J.H.4
Shen, L.5
Gupta, S.6
De Bono, J.S.7
-
27
-
-
34547119271
-
Activity of second-line chemotherapy in docetaxel-refractory hormone-refractory prostate cancer patients: Randomized phase 2 study of ixabepilone or mitoxantrone and prednisone
-
DOI 10.1002/cncr.22811
-
Rosenberg JE, Weinberg VK, Kelly WK, Michaelson D, Hussain MH, Wilding G, Gross M, Hutcheon D, Small EJ: Activity of secondline chemotherapy in docetaxel-refractory hormone-refractory prostate cancer patients: randomized phase 2 study of ixabepilone or mitoxantrone and prednisone. Cancer 2007; 110: 556-563. (Pubitemid 47106144)
-
(2007)
Cancer
, vol.110
, Issue.3
, pp. 556-563
-
-
Rosenberg, J.E.1
Weinberg, V.K.2
Kelly, W.K.3
Michaelson, D.4
Hussain, M.H.5
Wilding, G.6
Gross, M.7
Hutcheon, D.8
Small, E.J.9
-
28
-
-
9444227104
-
Randomised phase III study of intravenous vinorelbine plus hormone therapy versus hormone therapy alone in hormone-refractory prostate cancer
-
DOI 10.1093/annonc/mdh429
-
Abratt RP, Brune D, Dimopoulos MA, Kliment J, Breza J, Selvaggi FP, Beuzeboc P, Demkow T, Oudard S: Randomised phase III study of intravenous vinorelbine plus hormone therapy versus hormone therapy alone in hormone-refractory prostate cancer. Ann Oncol 2004; 15: 1613-1621. (Pubitemid 39562600)
-
(2004)
Annals of Oncology
, vol.15
, Issue.11
, pp. 1613-1621
-
-
Abratt, R.P.1
Brune, D.2
Dimopoulos, M.-A.3
Kliment, J.4
Breza, J.5
Selvaggi, F.P.6
Beuzeboc, P.7
Demkow, T.8
Oudard, S.9
-
29
-
-
61649126264
-
Phase II trial of weekly patupilone in patients with castration-resistant prostate cancer
-
Hussain A, DiPaola RS, Baron AD, Higano CS, Tchekmedyian NS, Johri AR: Phase II trial of weekly patupilone in patients with castration-resistant prostate cancer. Ann Oncol 2009; 20: 492-497.
-
(2009)
Ann Oncol
, vol.20
, pp. 492-497
-
-
Hussain, A.1
Dipaola, R.S.2
Baron, A.D.3
Higano, C.S.4
Tchekmedyian, N.S.5
Johri, A.R.6
-
30
-
-
78650346128
-
Randomized phase II trial of patupilone plus prednisone versus docetaxel plus prednisone in patients with chemotherapy-naive, metastatic, castrate-resistant prostate cancer (CRPC) (abstract)
-
De Souza PL, Mellado B, Pfister C, Rosenthal M, Castellano DE, Weber D, Ferrara S, Shaikh N, Tan E, Patterson SG: Randomized phase II trial of patupilone plus prednisone versus docetaxel plus prednisone in patients with chemotherapy-naive, metastatic, castrate-resistant prostate cancer (CRPC) (abstract). J Clin Oncol 2010; 28(15s): 4553.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15 S
, pp. 4553
-
-
De Souza, P.L.1
Mellado, B.2
Pfister, C.3
Rosenthal, M.4
Castellano, D.E.5
Weber, D.6
Ferrara, S.7
Shaikh, N.8
Tan, E.9
Patterson, S.G.10
-
31
-
-
20944439837
-
Phase III trial of satraplatin, an oral platinum plus prednisone vs. prednisone alone in patients with hormone-refractory prostate cancer
-
DOI 10.1159/000084201
-
Sternberg CN, Whelan P, Hetherington J, Paluchowska B, Slee PH, Vekemans K, Van Erps P, Theodore C, Koriakine O, Oliver T, Lebwohl D, Debois M, Zurlo A, Collette L: Phase III trial of satraplatin, an oral platinum plus prednisone vs. prednisone alone in patients with hormone-refractory prostate cancer. Oncology 2005; 68: 2-9. (Pubitemid 40675002)
-
(2005)
Oncology
, vol.68
, Issue.1
, pp. 2-9
-
-
Sternberg, C.N.1
Whelan, P.2
Hetherington, J.3
Paluchowska, B.4
Slee, P.H.Th.J.5
Vekemans, K.6
Van Erps, P.7
Theodore, C.8
Koriakine, O.9
Oliver, T.10
Lebwohl, D.11
Debois, M.12
Zurlo, A.13
Collette, L.14
-
32
-
-
73949098659
-
Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: The SPARC trial
-
Sternberg CN, Petrylak DP, Sartor O, Witjes JA, Demkow T, Ferrero JM, Eymard JC, Falcon S, Calabro F, James N, Bodrogi I, Harper P, Wirth M, Berry W, Petrone ME, McKearn TJ, Noursalehi M, George M, Rozencweig M: Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: the SPARC trial. J Clin Oncol 2009; 27: 5431-5438.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5431-5438
-
-
Sternberg, C.N.1
Petrylak, D.P.2
Sartor, O.3
Witjes, J.A.4
Demkow, T.5
Ferrero, J.M.6
Eymard, J.C.7
Falcon, S.8
Calabro, F.9
James, N.10
Bodrogi, I.11
Harper, P.12
Wirth, M.13
Berry, W.14
Petrone, M.E.15
McKearn, T.J.16
Noursalehi, M.17
George, M.18
Rozencweig, M.19
-
33
-
-
0344010948
-
Migration and Invasion of Human Prostate Cancer Cells is Related to Expression of VEGF and Its Receptors
-
Qi L, Robinson WA, Brady BM, Glode LM: Migration and invasion of human prostate cancer cells is related to expression of VEGF and its receptors. Anticancer Res 2003; 23: 3917-3922. (Pubitemid 37474343)
-
(2003)
Anticancer Research
, vol.23
, Issue.5 A
, pp. 3917-3922
-
-
Qi, L.1
Robinson, W.A.2
Brady, B.M.R.3
Glode, L.M.4
-
34
-
-
4043157141
-
Metastatic properties of prostate cancer cells are controlled by VEGF
-
DOI 10.1080/15419060490471739
-
Chen J, De S, Brainard J, Byzova TV: Metastatic properties of prostate cancer cells are controlled by VEGF. Cell Commun Adhes 2004; 11: 1-11. (Pubitemid 39069726)
-
(2004)
Cell Communication and Adhesion
, vol.11
, Issue.1
, pp. 1-11
-
-
Chen, J.1
De, S.2
Brainard, J.3
Byzova, T.V.4
-
35
-
-
75949107937
-
VEGF inhibitors and prostate cancer therapy
-
Aragon-Ching JB, Dahut WL: VEGF inhibitors and prostate cancer therapy. Curr Mol Pharmacol 2009; 2: 161-168.
-
(2009)
Curr Mol Pharmacol
, vol.2
, pp. 161-168
-
-
Aragon-Ching, J.B.1
Dahut, W.L.2
-
36
-
-
0346880557
-
The use of bevacizumab (B) with docetaxel (D) and estramustine (E) in hormone refractory prostate cancer (HRPC): Initial results of CALGB 90006 (abstract 1578)
-
Picus J, Halabi S, Rini B, Vogelzang NJ, Whang Y, Kaplan E, Kelly W, Small E: The use of bevacizumab (B) with docetaxel (D) and estramustine (E) in hormone refractory prostate cancer (HRPC): initial results of CALGB 90006 (abstract 1578). Proc Am Soc Clin Oncol 2003; 22:393.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 393
-
-
Picus, J.1
Halabi, S.2
Rini, B.3
Vogelzang, N.J.4
Whang, Y.5
Kaplan, E.6
Kelly, W.7
Small, E.8
-
37
-
-
53249135560
-
Combination of bevacizumab and docetaxel in docetaxel-pretreated hormonerefractory prostate cancer: A phase 2 study
-
Di Lorenzo G, Figg WD, Fossa SD, Mirone V, Autorino R, Longo N, Imbimbo C, Perdona S, Giordano A, Giuliano M, Labianca R, De Placido S: Combination of bevacizumab and docetaxel in docetaxel-pretreated hormonerefractory prostate cancer: a phase 2 study. Eur Urol 2008; 54: 1089-1094.
-
(2008)
Eur Urol
, vol.54
, pp. 1089-1094
-
-
Di Lorenzo, G.1
Figg, W.D.2
Fossa, S.D.3
Mirone, V.4
Autorino, R.5
Longo, N.6
Imbimbo, C.7
Perdona, S.8
Giordano, A.9
Giuliano, M.10
Labianca, R.11
De Placido, S.12
-
38
-
-
79960728298
-
Docetaxel versus docetaxel plus bevacizumab in progressive castration-resistant prostate cancer following first-line docetaxel (abstract)
-
Heidenreich A, Pfister DJ, Thüer D, Brehmer B: Docetaxel versus docetaxel plus bevacizumab in progressive castration-resistant prostate cancer following first-line docetaxel (abstract). J Clin Oncol 2010; 28(15s):e15006.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15 S
-
-
Heidenreich, A.1
Pfister, D.J.2
Thüer, D.3
Brehmer, B.4
-
39
-
-
77955714649
-
A randomized, double-blind, placebo-controlled phase III trial comparing docetaxel, prednisone, and placebo with docetaxel, prednisone, and bevacizumab in men with metastatic castration-resistant prostate cancer (MCRPC): Survival results of CALGB 90401 (abstract)
-
Kelly WK, Halabi S, Carducci MA, George DJ, Mahoney JF, Stadler WM, Morris MJ, Kantoff P, Monk JP, Small E: A randomized, double-blind, placebo-controlled phase III trial comparing docetaxel, prednisone, and placebo with docetaxel, prednisone, and bevacizumab in men with metastatic castration-resistant prostate cancer (MCRPC): survival results of CALGB 90401 (abstract). J Clin Oncol 2010; 28(18s):LBA4511.
-
(2010)
J Clin Oncol
, vol.28
, Issue.18 S
-
-
Kelly, W.K.1
Halabi, S.2
Carducci, M.A.3
George, D.J.4
Mahoney, J.F.5
Stadler, W.M.6
Morris, M.J.7
Kantoff, P.8
Monk, J.P.9
Small, E.10
-
40
-
-
77952223624
-
Tasquinimod (ABR-215050), a quinoline-3-carboxamide antiangiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors
-
Olsson A, Bjork A, Vallon-Christersson J, Isaacs JT, Leanderson T: Tasquinimod (ABR-215050), a quinoline-3-carboxamide antiangiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors. Mol Cancer 2010; 9: 107.
-
(2010)
Mol Cancer
, vol.9
, pp. 107
-
-
Olsson, A.1
Bjork, A.2
Vallon-Christersson, J.3
Isaacs, J.T.4
Leanderson, T.5
-
41
-
-
34248192988
-
The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts
-
DOI 10.1002/pros.20573
-
Dalrymple SL, Becker RE, Isaacs JT: The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts. Prostate 2007; 67: 790-797. (Pubitemid 46709447)
-
(2007)
Prostate
, vol.67
, Issue.7
, pp. 790-797
-
-
Dalrymple, S.L.1
Becker, R.E.2
Isaacs, J.T.3
-
42
-
-
70349952393
-
Open-label, clinical phase i studies of tasquinimod in patients with castration-resistant prostate cancer
-
Bratt O, Haggman M, Ahlgren G, Nordle O, Bjork A, Damber JE: Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer. Br J Cancer 2009; 101: 1233-1240.
-
(2009)
Br J Cancer
, vol.101
, pp. 1233-1240
-
-
Bratt, O.1
Haggman, M.2
Ahlgren, G.3
Nordle, O.4
Bjork, A.5
Damber, J.E.6
-
43
-
-
77955710046
-
A randomized, multicenter, international phase II study of tasquinim-od in chemotherapy naive patients with metastatic castrate-resistant prostate cancer (CRPC) (abstract)
-
Pili R, Haggman M, Stadler W, Gingrich J, Assikis V, Björk A, Forsberg G, Carducci M, Armstrong AJ: A randomized, multicenter, international phase II study of tasquinim-od in chemotherapy naive patients with metastatic castrate-resistant prostate cancer (CRPC) (abstract). J Clin Oncol 2010; 28(15s):4510.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15 S
, pp. 4510
-
-
Pili, R.1
Haggman, M.2
Stadler, W.3
Gingrich, J.4
Assikis, V.5
Björk, A.6
Forsberg, G.7
Carducci, M.8
Armstrong, A.J.9
-
44
-
-
0041464540
-
Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: An endothelin receptor antagonist for refractory prostate cancer
-
Zonnenberg BA, Groenewegen G, Janus TJ, Leahy TW, Humerickhouse RA, Isaacson JD, Carr RA, Voest E: Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: an endothelin receptor antagonist for refractory prostate cancer. Clin Cancer Res 2003; 9: 2965-2972. (Pubitemid 37006310)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.8
, pp. 2965-2972
-
-
Zonnenberg, B.A.1
Groenewegen, G.2
Janus, T.J.3
Leahy, T.W.4
Humerickhouse, R.A.5
Isaacson, J.D.6
Carr, R.A.7
Voest, E.8
-
45
-
-
0037441843
-
Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: A randomized, phase II, placebo-controlled trial
-
DOI 10.1200/JCO.2003.04.176
-
Carducci MA, Padley RJ, Breul J, Vogelzang NJ, Zonnenberg BA, Daliani DD, Schulman CC, Nabulsi AA, Humerickhouse RA, Weinberg MA, Schmitt JL, Nelson JB: Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial. J Clin Oncol 2003; 21: 679-689. (Pubitemid 46621903)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.4
, pp. 679-689
-
-
Carducci, M.A.1
Padley, R.J.2
Breul, J.3
Vogelzang, N.J.4
Zonnenberg, B.A.5
Daliani, D.D.6
Schulman, C.C.7
Nabulsi, A.A.8
Humerickhouse, R.A.9
Weinberg, M.A.10
Schmitt, J.L.11
Nelson, J.B.12
-
46
-
-
35648968713
-
A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer
-
DOI 10.1002/cncr.22996
-
Carducci MA, Saad F, Abrahamsson PA, Dearnaley DP, Schulman CC, North SA, Sleep DJ, Isaacson JD, Nelson JB: A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer. Cancer 2007; 110: 1959-1966. (Pubitemid 350036854)
-
(2007)
Cancer
, vol.110
, Issue.9
, pp. 1959-1966
-
-
Carducci, M.A.1
Saad, F.2
Abrahamsson, P.-A.3
Dearnaley, D.P.4
Schulman, C.C.5
North, S.A.6
Sleep, D.J.7
Isaacson, J.D.8
Nelson, J.B.9
-
47
-
-
55549112219
-
Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer
-
Nelson JB, Love W, Chin JL, Saad F, Schulman CC, Sleep DJ, Qian J, Steinberg J, Carducci M: Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer. Cancer 2008; 113: 2478-2487.
-
(2008)
Cancer
, vol.113
, pp. 2478-2487
-
-
Nelson, J.B.1
Love, W.2
Chin, J.L.3
Saad, F.4
Schulman, C.C.5
Sleep, D.J.6
Qian, J.7
Steinberg, J.8
Carducci, M.9
-
48
-
-
58149143013
-
A phase I-II study of docetaxel and atrasentan in men with castration-resistant metastatic prostate cancer
-
Armstrong AJ, Creel P, Turnbull J, Moore C, Jaffe TA, Haley S, Petros W, Yenser S, Gockerman JP, Sleep D, Hurwitz H, George DJ: A phase I-II study of docetaxel and atrasentan in men with castration-resistant metastatic prostate cancer. Clin Cancer Res 2008; 14: 6270-6276.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6270-6276
-
-
Armstrong, A.J.1
Creel, P.2
Turnbull, J.3
Moore, C.4
Jaffe, T.A.5
Haley, S.6
Petros, W.7
Yenser, S.8
Gockerman, J.P.9
Sleep, D.10
Hurwitz, H.11
George, D.J.12
-
49
-
-
62649134676
-
Safety and efficacy of the specific endothelin - A receptor antagonist zd4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: A double-blind, placebo-controlled, randomised, phase 2 trial
-
James ND, Caty A, Borre M, Zonnenberg BA, Beuzeboc P, Morris T, Phung D, Dawson NA: Safety and efficacy of the specific endothelin - a receptor antagonist zd4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: a double-blind, placebo-controlled, randomised, phase 2 trial. Eur Urol 2009; 55: 1112-1123.
-
(2009)
Eur Urol
, vol.55
, pp. 1112-1123
-
-
James, N.D.1
Caty, A.2
Borre, M.3
Zonnenberg, B.A.4
Beuzeboc, P.5
Morris, T.6
Phung, D.7
Dawson, N.A.8
-
50
-
-
65349186800
-
Aflibercept (AVE0005): An alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors
-
Chu QS: Aflibercept (AVE0005): an alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors. Expert Opin Biol Ther 2009; 9: 263-271.
-
(2009)
Expert Opin Biol Ther
, vol.9
, pp. 263-271
-
-
Chu, Q.S.1
-
51
-
-
67049171301
-
Phase i study of oral lenalidomide in patients with refractory metastatic cancer
-
Dahut WL, Aragon-Ching JB, Woo S, Tohnya TM, Gulley JL, Arlen PM, Wright JJ, Ventiz J, Figg WD: Phase I study of oral lenalidomide in patients with refractory metastatic cancer. J Clin Pharmacol 2009; 49: 650-660.
-
(2009)
J Clin Pharmacol
, vol.49
, pp. 650-660
-
-
Dahut, W.L.1
Aragon-Ching, J.B.2
Woo, S.3
Tohnya, T.M.4
Gulley, J.L.5
Arlen, P.M.6
Wright, J.J.7
Ventiz, J.8
Figg, W.D.9
-
52
-
-
75749158167
-
A modular phase i study of lenalidomide and paclitaxel in metastatic castration-resistant prostate cancer following prior taxane therapy
-
Mathew P, Tannir N, Tu SM, Carter CM, Bekele NB, Pagliaro L: A modular phase I study of lenalidomide and paclitaxel in metastatic castration-resistant prostate cancer following prior taxane therapy. Cancer Chemother Pharmacol 2010; 65: 811-815.
-
(2010)
Cancer Chemother Pharmacol
, vol.65
, pp. 811-815
-
-
Mathew, P.1
Tannir, N.2
Tu, S.M.3
Carter, C.M.4
Bekele, N.B.5
Pagliaro, L.6
-
53
-
-
2942518111
-
Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer
-
Saad F, Gleason DM, Murray R, Tchekmedyian S, Venner P, Lacombe L, Chin JL, Vinholes JJ, Goas JA, Zheng M: Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. J Natl Cancer Inst 2004; 96: 879-882. (Pubitemid 38807610)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.11
, pp. 879-882
-
-
Saad, F.1
Gleason, D.M.2
Murray, R.3
Tchekmedyian, S.4
Venner, P.5
Lacombe, L.6
Chin, J.L.7
Vinholes, J.J.8
Goas, J.A.9
Zheng, M.10
-
54
-
-
58749100624
-
Docetaxel/zoledronic acid combination triggers apoptosis synergistically through downregulating antiapoptotic bcl-2 protein level in hormone-refractory prostate cancer cells
-
Karabulut B, Erten C, Gul MK, Cengiz E, Karaca B, Kucukzeybek Y, Gorumlu G, Atmaca H, Uzunoglu S, Sanli UA, Baran Y, Uslu R: Docetaxel/zoledronic acid combination triggers apoptosis synergistically through downregulating antiapoptotic bcl-2 protein level in hormone-refractory prostate cancer cells. Cell Biol Int 2009; 33: 239-246.
-
(2009)
Cell Biol Int
, vol.33
, pp. 239-246
-
-
Karabulut, B.1
Erten, C.2
Gul, M.K.3
Cengiz, E.4
Karaca, B.5
Kucukzeybek, Y.6
Gorumlu, G.7
Atmaca, H.8
Uzunoglu, S.9
Sanli, U.A.10
Baran, Y.11
Uslu, R.12
-
55
-
-
78349290889
-
A randomized phase II trial of denosumab versus zoledronic acid in patients with bone metastases from castration-resistant prostate cancer (abstract)
-
Fizazi K, Carducci M, Smith MR, Damiao R, Brown JE, Karsh L, Milecki P, Wang H, Dansey RD, Goessl CD: A randomized phase II trial of denosumab versus zoledronic acid in patients with bone metastases from castration-resistant prostate cancer (abstract). J Clin Oncol 2010; 28(18s)LBA4507.
-
(2010)
J Clin Oncol
, vol.28
, Issue.18 S
-
-
Fizazi, K.1
Carducci, M.2
Smith, M.R.3
Damiao, R.4
Brown, J.E.5
Karsh, L.6
Milecki, P.7
Wang, H.8
Dansey, R.D.9
Goessl, C.D.10
-
56
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff P, Higano CS, Shore ND, Berger ER, Small E, Penson DF, Redfern CH, Ferrari AC, Dreicer R, Sims RB, Xu Y, Frohlich M, Schellhammer P: Sipuleucel-T immunotherapy for castration-resistant prostate cancer N Engl J Med 2010; 363: 411-422.
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.1
Higano, C.S.2
Shore, N.D.3
Berger, E.R.4
Small, E.5
Penson, D.F.6
Redfern, C.H.7
Ferrari, A.C.8
Dreicer, R.9
Sims, R.B.10
Xu, Y.11
Frohlich, M.12
Schellhammer, P.13
|