Rab15 expression correlates with retinoic acid-induced differentiation of neuroblastoma cells

Oncology Reports

Volumn 26, Issue 1, 2011, Pages 145-151

  Nishimura, Noriyuki ^a   Pham, Thi Van Huyen ^a   Hartomo, Tri Budi ^a   Lee, Myeong Jin ^a   Hasegawa, Dahchiro ^b   Takeda, Hiroki ^b   Kawasaki, Kehchiro ^b   Kosaka, Yoshiyuki ^b   Yamamoto, Tomoto ^a   Morikawa, Satoru ^a   Yamamoto, Nobuyuki ^a   Kubokawa, Ikuko ^a   Mori, Takeshi ^a   Yanai, Tomoko ^a   Hayakawa, Akira ^a   Takeshima, Yasuhiro ^a   Nishio, Hisahide ^a   Matsuo, Masafumi ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Hyogo Children's Hospital   (Japan)

Author keywords

Alternative splicing; Neuroblastoma; Rab15; Retinoic acid

Indexed keywords

CD57 ANTIGEN; COMPLEMENTARY DNA; GLUCURONOSYLTRANSFERASE; RAB 15 PROTEIN; RAB PROTEIN; RETINOIC ACID; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRUCTURE; CONTROLLED STUDY; DNA SEQUENCE; ENDOCYTOSIS; EXON; HIGH RISK PATIENT; HUMAN; HUMAN CELL; NERVE CELL DIFFERENTIATION; NEUROBLASTOMA CELL; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TESTIS; UPREGULATION;

ALTERNATIVE SPLICING; APOPTOSIS; CELL DIFFERENTIATION; CHILD; CHILD, PRESCHOOL; EXONS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICROSCOPY, FLUORESCENCE; NEUROBLASTOMA; NEURONS; PROTEIN ISOFORMS; RAB GTP-BINDING PROTEINS;

EID: 79955870075     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1255     Document Type: Article

References (30)

1. Janoueix-Lerosey I, Schleiermacher G and Delattre O: Molecular pathogenesis of peripheral neuroblastic tumors. Oncogene 29: 1566-1579, 2010.
2. Maris JM, Hogarty MD, Bagatell R and Cohn SL: Neuroblastoma. Lancet 369: 2106-2120, 2007. (Pubitemid 46935947)
3. Brodeur GM: Neuroblastoma biological insights into a clinical enigma Nat Rev Cancer 3: 203-216, 2003.
4. Reynolds CP, Matthay KK, Villablanca JG and Maurer BJ: Retinoid therapy of high-risk neuroblastoma. Cancer Lett 197: 185-192, 2003. (Pubitemid 36860009)
5. Wagner LM and Danks MK: New therapeutic targets for the treatment of high-risk neuroblastoma. J Cell Biochem 107: 46-57, 2009.
6. Ciccarone V, Spengler BA, Meyers MB, Biedler JL and Ross RA: Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages. Cancer Res 49: 219-225, 1989. (Pubitemid 19024435)
7. Ross RA, Biedler JL and Spengler BA: A role for distinct cell types in determining malignancy in human neuroblastoma cell lines and tumors. Cancer Lett 197: 35-39, 2003. (Pubitemid 36859987)
8. Ross RA, Spengler BA, Domènech C, Porubcin M, Rettig WJ and Biedler JL: Human neuroblastoma I-type cells are malignant neural crest stem cells. Cell Growth Differ 6: 449-456, 1995.
9. Takai Y, Sasaki T and Matozaki T: Small GTP-binding proteins. Physiol Rev 81: 153-208, 2001. (Pubitemid 32098004)
10. Nishimura N and Sasaki T: Rab family small G proteins in regulation of epithelial apical junctions. Front Biosci 14: 2115-2129, 2009.
11. Stenmark H: Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol 10: 513-525, 2009.
12. Chia WJ and Tang BL: Emerging roles for Rab family GTPases in human cancer. Biochim Biophys Acta 1795: 110-116, 2009.
13. Culine S, Rousseau-Merck MF, Honoré N, Nezelof C and Olofsson B: Specific expression of the ras-related rab3A gene in human normal and malignant neuroendocrine cells. Cancer 70: 2552-2556, 1992.
14. Liu Y-J, Wang Q, Li W, et al: Rab23 is a potential biological target for treating hepatocellular carcinoma. World J Gastroenterol 13: 1010-1017, 2007. (Pubitemid 46511001)
15. Hou Q, Wu YH, Grabsch H, et al: Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer. Cancer Res 68: 4623-4630, 2008.
16. Cheng KW, Lahad JP, Kuo W, et al: The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers. Nat Med 10: 1251-1256, 2004. (Pubitemid 39540444)
17. Zhang J, Liu X, Datta A, et al: RCP is a human breast cancer-promoting gene with Ras-activating function. J Clin Invest 119: 2171-2183, 2009.
18. Maxwell CA, Rasmussen E, Zhan F, et al. RHAMM expression and isoform balance predict aggressive disease and poorsurvival in multiple myeloma Blood 104: 1151-1158, 2004.
19. Adamia S, Reiman T, Crainie M, Mant MJ, Belch AR and Pilarski LM: Intronic splicing of hyaluronan synthase 1 (HAS1): a biologically relevant indicator of poor outcome in multiple myeloma Blood 105: 4836-4844, 2005.
20. Venables JP: Unbalanced alternative splicing and its significance in cancer. Bioessays 28: 378-386, 2006.
21. Ward AJ and Cooper TA: The pathobiology of splicing. J Pathol 220: 152-163, 2010.
22. Elferink LA, Anzai K and Scheller RH: rab15, a novel low molecular weight GTP-binding protein specifically expressed in rat brain. J Biol Chem 267: 5768-5775, 1992.
23. Zuk PA and Elferink LA: Rab15 differentially regulates early endocytic trafficking. J Biol Chem 275: 26754-26764, 2000.
24. Valencia A, Chardin P, Wittinghofer A and Sander C: The ras protein family: evolutionary tree and role of conserved amino acids. Biochemistry 30: 4637-4648, 1991.
25. Joshi S, Guleria RS, Pan J, Dipette D and Singh US: Heterogeneity in retinoic acid signaling in neuroblastomas: role of matrix metalloproteinases in retinoic acid-induced differentiation Biochim Biophys Acta 1772: 1093-1102, 2007.
26. Cooper MJ, Steinberg SM, Chatten J, Evans AE and Israel MA: Plasticity of neuroblastoma tumor cells to differentiate along a fetal adrenal ganglionic lineage predicts for improved patient survival. J Clin Invest 90: 2402-2408, 1992. (Pubitemid 23010059)
27. Carlei F, Polak JM, Ceccamea A, et al: Neuronal and glial markers in tumours of neuroblastic origin. Virchows Archiv A Pathol Anat Histopathol 404: 313-324, 1984. (Pubitemid 14006392)
28. Echard A, Opdam FJ, de Leeuw HJ, et al: Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms. Mol Biol Cell 11: 3819-3833, 2000.
29. Brauers A, Schürmann A, Massmann S, et al: Alternative mRNA splicing of the novel GTPase Rab28 generates isoforms with different C-termini. Eur J Biochem 237: 833-840, 1996. (Pubitemid 26157672)
30. Weinstein JL, Katzenstein HM and Cohn SL: Advances in the diagnosis and treatment of neuroblastoma. Oncologist 8: 278-292, 2003.