Etiologic Differences Between Seminoma and Nonseminoma of the Testis: A Systematic Review of Epidemiologic Studies

Hematology/Oncology Clinics of North America

Volumn 25, Issue 3, 2011, Pages 473-486

  Stang, Andreas ^a   Kuss, Oliver ^b  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b MARTIN LUTHER UNIVERSITÄT HALLE WITTENBERG   (Germany)

Author keywords

Epidemiology; Etiology; Nonseminoma; Seminoma; Systematic review; Testicular neoplasms

Indexed keywords

CANCER RISK; CASE CONTROL STUDY; COHORT ANALYSIS; HISTOPATHOLOGY; HUMAN; PRIORITY JOURNAL; REVIEW; SEMINOMA; SYSTEMATIC REVIEW (TOPIC); TESTIS NONSEMINOMA CANCER;

AGED; CASE-CONTROL STUDIES; COHORT STUDIES; HUMANS; INFANT; INFANT, NEWBORN; MALE; RISK FACTORS; SEMINOMA; TESTICULAR NEOPLASMS;

EID: 79955862524     PISSN: 08898588     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hoc.2011.03.003     Document Type: Review

References (95)

1. Woodward P.J., Mostofi F.K., Talerman A., et al. Germ cell tumours. Pathology and genetics of tumours of the urinary system and male genital organs 2004, 221-249. IARC Press, Lyon (France). 1st edition. J.N. Eble, G. Sauter, J.I. Epstein (Eds.).
2. McGlynn K.A., Cook M.B. Etiologic factors in testicular germ-cell tumors. Future Oncol 2009, 5:1389-1402.
3. Horwich A., Shipley J., Huddart R. Testicular germ-cell cancer. Lancet 2006, 367:754-765.
4. Oosterhuis J.W., Looijenga L.H. Testicular germ-cell tumours in a broader perspective. Nat Rev Cancer 2005, 5:210-222.
5. Bray F., Richiardi L., Ekbom A., et al. Do testicular seminoma and nonseminoma share the same etiology? Evidence from an age-period-cohort analysis of incidence trends in eight European countries. Cancer Epidemiol Biomarkers Prev 2006, 15:652-658.
6. Bray F., Ferlay J., Devesa S.S., et al. Interpreting the international trends in testicular seminoma and nonseminoma incidence. Nat Clin Pract Urol 2006, 3:532-543.
7. Liu S., Semenciw R., Waters C., et al. Clues to the aetiological heterogeneity of testicular seminomas and non-seminomas: time trends and age-period-cohort effects. Int J Epidemiol 2000, 29:826-831.
8. Stang A., Jöckel K.H. Etiologic conclusions from similar birth cohort effects. Cancer Epidemiol Biomarkers Prev 2006, 15:1752-1753.
9. Chia V.M., Quraishi S.M., Devesa S.S., et al. International trends in the incidence of testicular cancer, 1973-2002. Cancer Epidemiol Biomarkers Prev 2010, 19:1151-1159.
10. Aschim E.L., Haugen T.B., Tretli S., et al. Risk factors for testicular cancer-differences between pure non-seminoma and mixed seminoma/non-seminoma?. Int J Androl 2006, 29:458-467.
11. Xu Q., Pearce M.S., Parker L. Incidence and survival for testicular germ cell tumor in young males: a report from the Northern Region Young Person's Malignant Disease Registry, United Kingdom. Urol Oncol 2007, 25:32-37.
12. Stang A., Rusner C., Eisinger B., et al. Subtype-specific incidence of testicular cancer in Germany: a pooled analysis of nine population-based cancer registries. Int J Androl 2007, 30:1-11.
13. Walsh T.J., Grady R.W., Porter M.P., et al. Incidence of testicular germ cell cancers in U.S. children: SEER program experience 1973 to 2000. Urology 2006, 68:402-405.
14. Stang A. Etiology of testicular germ cell tumors: lumping or splitting? A plea against lumping. Eur J Epidemiol 2009, 24:65-67.
15. Grotmol T., Weiderpass E., Tretli S. Conditions in utero and cancer risk. Eur J Epidemiol 2006, 21:561-570.
16. Akre O., Pettersson A., Richiardi L. Risk of contralateral testicular cancer among men with unilaterally undescended testis: a meta analysis. Int J Cancer 2009, 124:687-689.
17. Aschim E.L., Grotmol T., Tretli S., et al. Is there an association between maternal weight and the risk of testicular cancer? An epidemiologic study of Norwegian data with emphasis on World War II. Int J Cancer 2005, 116:327-330.
18. Kedem B., Kim E.Y., Voulgaraki A., et al. Two-dimensional semiparametric density ratio modeling of testicular germ cell data. Stat Med 2009, 28:2147-2159.
19. Chia V.M., Li Y., Goldin L.R., et al. Risk of cancer in first- and second-degree relatives of testicular germ cell tumor cases and controls. Int J Cancer 2009, 124:952-957.
20. Metcalfe S., Jones W.G. Testicular cancer: B5, a new tumour marker. Urol Int 1987, 42:254-259.
21. Braun M.M., Caporaso N.E., Page W.F., et al. Prevalence of a history of testicular cancer in a cohort of elderly twins. Acta Genet Med Gemellol (Roma) 1995, 44:189-192.
22. Prener A., Carstensen B. Month of birth and testicular cancer risk in Denmark. Am J Epidemiol 1990, 131:15-19.
23. Stang A., Ahrens W., Baumgardt-Elms C., et al. Adolescent milk fat and galactose consumption and testicular germ cell cancer. Cancer Epidemiol Biomarkers Prev 2006, 15:2189-2195.
24. Subrahmaniam K. A primer in probability 1979, Dekker, New York. 1st edition.
25. English P.B., Goldberg D.E., Wolff C., et al. Parental and birth characteristics in relation to testicular cancer risk among males born between 1960 and 1995 in California (United States). Cancer Causes Control 2003, 14:815-825.
26. Richiardi L., Akre O., Bellocco R., et al. Perinatal determinants of germ-cell testicular cancer in relation to histological subtypes. Br J Cancer 2002, 87:545-550.
27. Akre O., Ekbom A., Hsieh C.C., et al. Testicular nonseminoma and seminoma in relation to perinatal characteristics. J Natl Cancer Inst 1996, 88:883-889.
28. Akre O., Lipworth L., Tretli S., et al. Epstein-Barr virus and cytomegalovirus in relation to testicular-cancer risk: a nested case-control study. Int J Cancer 1999, 82:1-5.
29. Holl K., Surcel H.M., Koskela P., et al. Maternal Epstein-Barr virus and cytomegalovirus infections and risk of testicular cancer in the offspring: a nested case-control study. APMIS 2008, 116:816-822.
30. Prener A., Hsieh C.C., Engholm G., et al. Birth order and risk of testicular cancer. Cancer Causes Control 1992, 3:265-272.
31. Chia V.M., Quraishi S.M., Graubard B.I., et al. Insulin-like growth factor 1, insulin-like growth factor-binding protein 3, and testicular germ-cell tumor risk. Am J Epidemiol 2008, 167:1438-1445.
32. Powles T., Bower M., Daugaard G., et al. Multicenter study of human immunodeficiency virus-related germ cell tumors. J Clin Oncol 2003, 21:1922-1927.
33. Coupland C.A., Chilvers C.E., Davey G., et al. Risk factors for testicular germ cell tumours by histological tumour type. United Kingdom Testicular Cancer Study Group. Br J Cancer 1999, 80:1859-1863.
34. Tolfvenstam T., Papadogiannakis N., Andersen A., et al. No association between human parvovirus B19 and testicular germ cell cancer. J Gen Virol 2002, 83:2321-2324.
35. Jacobsen R., Bostofte E., Engholm G., et al. Risk of testicular cancer in men with abnormal semen characteristics: cohort study. BMJ 2000, 321:789-792.
36. Baker J.A., Buck G.M., Vena J.E., et al. Fertility patterns prior to testicular cancer diagnosis. Cancer Causes Control 2005, 16:295-299.
37. Hardell L., Carlberg M., Ohlson C.G., et al. Use of cellular and cordless telephones and risk of testicular cancer. Int J Androl 2007, 30:115-122.
38. Prener A., Engholm G., Jensen O.M. Genital anomalies and risk for testicular cancer in Danish men. Epidemiology 1996, 7:14-19.
39. Weir H.K., Marrett L.D., Kreiger N., et al. Pre-natal and peri-natal exposures and risk of testicular germ-cell cancer. Int J Cancer 2000, 87:438-443.
40. Dusek L., Abrahamova J., Lakomy R., et al. Multivariate analysis of risk factors for testicular cancer: a hospital-based case-control study in the Czech Republic. Neoplasma 2008, 55:356-368.
41. Nori F., Carbone P., Giordano F., et al. Endocrine-disrupting chemicals and testicular cancer: a case-control study. Arch Environ Occup Health 2006, 61:87-95.
42. Patja K., Pukkala E., Sund R., et al. Cancer incidence of persons with Down syndrome in Finland: a population-based study. Int J Cancer 2006, 118:1769-1772.
43. McGlynn K.A., Sakoda L.C., Rubertone M.V., et al. Body size, dairy consumption, puberty, and risk of testicular germ cell tumors. Am J Epidemiol 2007, 165:355-363.
44. Moller H., Skakkebaek N.E. Risk of testicular cancer in subfertile men: case-control study. BMJ 1999, 318:559-562.
45. Doria-Rose V.P., Biggs M.L., Weiss N.S. Subfertility and the risk of testicular germ cell tumors (United States). Cancer Causes Control 2005, 16:651-656.
46. Hardell L., Bavel B., Lindstrom G., et al. In utero exposure to persistent organic pollutants in relation to testicular cancer risk. Int J Androl 2006, 29:228-234.
47. Hardell L., van Bavel B., Lindstrom G., et al. Increased concentrations of polychlorinated biphenyls, hexachlorobenzene, and chlordanes in mothers of men with testicular cancer. Environ Health Perspect 2003, 111:930-934.
48. Hardell L., Ohlson C.G., Fredrikson M. Occupational exposure to polyvinyl chloride as a risk factor for testicular cancer evaluated in a case-control study. Int J Cancer 1997, 73:828-830.
49. Garner M.J., Birkett N.J., Johnson K.C., et al. Dietary risk factors for testicular carcinoma. Int J Cancer 2003, 106:934-941.
50. Dieckmann K.P., Hartmann J.T., Classen J., et al. Tallness is associated with risk of testicular cancer: evidence for the nutrition hypothesis. Br J Cancer 2008, 99:1517-1521.
51. Richiardi L., Askling J., Granath F., et al. Body size at birth and adulthood and the risk for germ-cell testicular cancer. Cancer Epidemiol Biomarkers Prev 2003, 12:669-673.
52. Cook M.B., Zhang Y., Graubard B.I., et al. Risk of testicular germ-cell tumours in relation to childhood physical activity. Br J Cancer 2008, 98:174-178.
53. Littman A.J., Doody D.R., Biggs M.L., et al. Physical activity in adolescence and testicular germ cell cancer risk. Cancer Causes Control 2009, 20:1281-1290.
54. McGlynn K.A., Zhang Y., Sakoda L.C., et al. Maternal smoking and testicular germ cell tumors. Cancer Epidemiol Biomarkers Prev 2006, 15:1820-1824.
55. Daling J.R., Doody D.R., Sun X., et al. Association of marijuana use and the incidence of testicular germ cell tumors. Cancer 2009, 115:1215-1223.
56. Sigurdson A.J., Chang S., Annegers J.F., et al. A case-control study of diet and testicular carcinoma. Nutr Cancer 1999, 34:20-26.
57. Walcott F.L., Hauptmann M., Duphorne C.M., et al. A case-control study of dietary phytoestrogens and testicular cancer risk. Nutr Cancer 2002, 44:44-51.
58. Bonner M.R., McCann S.E., Moysich K.B. Dietary factors and the risk of testicular cancer. Nutr Cancer 2002, 44:35-43.
59. Ekbom A., Richiardi L., Akre O., et al. Age at immigration and duration of stay in relation to risk for testicular cancer among Finnish immigrants in Sweden. J Natl Cancer Inst 2003, 95:1238-1240.
60. Beiki O., Granath F., Allebeck P., et al. Subtype-specific risk of testicular tumors among immigrants and their descendants in Sweden, 1960 to 2007. Cancer Epidemiol Biomarkers Prev 2010, 19:1053-1065.
61. Tarone R.E., Hayes H.M., Hoover R.N., et al. Service in Vietnam and risk of testicular cancer. J Natl Cancer Inst 1991, 83:1497-1499.
62. Moller H. Work in agriculture, childhood residence, nitrate exposure, and testicular cancer risk: a case-control study in Denmark. Cancer Epidemiol Biomarkers Prev 1997, 6:141-144.
63. Verreault R., Weiss N.S., Hollenbach K.A., et al. Use of electric blankets and risk of testicular cancer. Am J Epidemiol 1990, 131:759-762.
64. Hayes R.B., Brown L.M., Pottern L.M., et al. Occupation and risk for testicular cancer: a case-control study. Int J Epidemiol 1990, 19:825-831.
65. Andersson E., Nilsson R., Toren K. Testicular cancer among Swedish pulp and paper workers. Am J Ind Med 2003, 43:642-646.
66. Ohlson C.G., Hardell L. Testicular cancer and occupational exposures with a focus on xenoestrogens in polyvinyl chloride plastics. Chemosphere 2000, 40:1277-1282.
67. Rhomberg W., Schmoll H.J., Schneider B. High frequency of metalworkers among patients with seminomatous tumors of the testis: a case-control study. Am J Ind Med 1995, 28:79-87.
68. Kristensen P., Andersen A., Irgens L.M., et al. Testicular cancer and parental use of fertilizers in agriculture. Cancer Epidemiol Biomarkers Prev 1996, 5:3-9.
69. Stenlund C., Floderus B. Occupational exposure to magnetic fields in relation to male breast cancer and testicular cancer: a Swedish case-control study. Cancer Causes Control 1997, 8:184-191.
70. Pettersson A., Richiardi L., Cnattingius S., et al. Gestational hypertension, preeclampsia, and risk of testicular cancer. Cancer Res 2008, 68:8832-8836.
71. Wanderas E.H., Grotmol T., Fossa S.D., et al. Maternal health and pre- and perinatal characteristics in the etiology of testicular cancer: a prospective population- and register-based study on Norwegian males born between 1967 and 1995. Cancer Causes Control 1998, 9:475-486.
72. Moller H., Skakkebaek N.E. Testicular cancer and cryptorchidism in relation to prenatal factors: case-control studies in Denmark. Cancer Causes Control 1997, 8:904-912.
73. Westergaard T., Andersen P.K., Pedersen J.B., et al. Testicular cancer risk and maternal parity: a population-based cohort study. Br J Cancer 1998, 77:1180-1185.
74. Richiardi L., Akre O., Lambe M., et al. Birth order, sibship size, and risk for germ-cell testicular cancer. Epidemiology 2004, 15:323-329.
75. Moller H., Skakkebaek N.E. Risks of testicular cancer and cryptorchidism in relation to socio-economic status and related factors: case-control studies in Denmark. Int J Cancer 1996, 66:287-293.
76. Cook M.B., Graubard B.I., Rubertone M.V., et al. Perinatal factors and the risk of testicular germ cell tumors. Int J Cancer 2008, 122:2600-2606.
77. Sabroe S., Olsen J. Perinatal correlates of specific histological types of testicular cancer in patients below 35 years of age: a case-cohort study based on midwives' records in Denmark. Int J Cancer 1998, 78:140-143.
78. Tuomisto J., Holl K., Rantakokko P., et al. Maternal smoking during pregnancy and testicular cancer in the sons: a nested case-control study and a meta-analysis. Eur J Cancer 2009, 45:1640-1648.
79. Pettersson A., Akre O., Richiardi L., et al. Maternal smoking and the epidemic of testicular cancer-a nested case-control study. Int J Cancer 2007, 120:2044-2046.
80. Coupland C.A., Forman D., Chilvers C.E., et al. Maternal risk factors for testicular cancer: a population-based case-control study (UK). Cancer Causes Control 2004, 15:277-283.
81. Petridou E., Roukas K.I., Dessypris N., et al. Baldness and other correlates of sex hormones in relation to testicular cancer. Int J Cancer 1997, 71:982-985.
82. Holl K., Lundin E., Surcel H.M., et al. Endogenous steroid hormone levels in early pregnancy and risk of testicular cancer in the offspring: a nested case-referent study. Int J Cancer 2009, 124:2923-2928.
83. Ramlau-Hansen C.H., Olesen A.V., Parner E.T., et al. Perinatal markers of estrogen exposure and risk of testicular cancer: follow-up of 1,333,873 Danish males born between 1950 and 2002. Cancer Causes Control 2009, 20:1587-1592.
84. Cook M.B., Graubard B.I., Quraishi S.M., et al. Genetic variants in the 8q24 locus and risk of testicular germ cell tumors. Hum Genet 2008, 123:409-418.
85. Kanetsky P.A., Mitra N., Vardhanabhuti S., et al. Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. Nat Genet 2009, 41:811-815.
86. Purdue M.P., Graubard B.I., Chanock S.J., et al. Genetic variation in the inhibin pathway and risk of testicular germ cell tumors. Cancer Res 2008, 68:3043-3048.
87. Purdue M.P., Sakoda L.C., Graubard B.I., et al. A case-control investigation of immune function gene polymorphisms and risk of testicular germ cell tumors. Cancer Epidemiol Biomarkers Prev 2007, 16:77-83.
88. Figueroa J.D., Sakoda L.C., Graubard B.I., et al. Genetic variation in hormone metabolizing genes and risk of testicular germ cell tumors. Cancer Causes Control 2008, 19:917-929.
89. Rapley E.A., Turnbull C., Al Olama A.A., et al. A genome-wide association study of testicular germ cell tumor. Nat Genet 2009, 41:807-810.
90. Vistisen K., Prieme H., Okkels H., et al. Genotype and phenotype of glutathione S-transferase mu in testicular cancer patients. Pharmacogenetics 1997, 7:21-25.
91. Dong C., Lonnstedt I., Hemminki K. Familial testicular cancer and second primary cancers in testicular cancer patients by histological type. Eur J Cancer 2001, 37:1878-1885.
92. Bromen K., Stang A., Baumgardt-Elms C., et al. Testicular, other genital, and breast cancers in first-degree relatives of testicular cancer patients and controls. Cancer Epidemiol Biomarkers Prev 2004, 13:1316-1324.
93. Hemminki K., Chen B. Familial risks in testicular cancer as aetiological clues. Int J Androl 2006, 29:205-210.
94. Kaijser M., Akre O., Cnattingius S., et al. Maternal lung cancer and testicular cancer risk in the offspring. Cancer Epidemiol Biomarkers Prev 2003, 12:643-646.
95. Stang A., Poole C., Kuss O. The ongoing tyranny of statistical significance testing in biomedical research. Eur J Epidemiol 2010, 25:225-230.