Antibiotic prophylaxis in pediatric urology: An update

Current Urology Reports

Volumn 12, Issue 2, 2011, Pages 126-131

  Greenfield, Saul P ^a,b  

^a CHILDREN S HOSPITAL OF BUFFALO   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

Antenatal hydronephrosis; Antibiotic prophylaxis; Circumcision; Ureteropelvic junction obstruction; Ureterovesical junction obstruction; Urinary tract infection; Vesicoureteral reflux; Voiding dysfunction

Indexed keywords

ANTIBIOTIC AGENT; CEPHALOSPORIN; COTRIMOXAZOLE; NITROFURANTOIN; PLACEBO;

ANTIBIOTIC PROPHYLAXIS; ARTICLE; ATTITUDE TO HEALTH; CHILD UROLOGY; CIRCUMCISION; CLINICAL EFFECTIVENESS; DRUG EFFICACY; DRUG USE; DRUG WITHDRAWAL; GASTROINTESTINAL SYMPTOM; HUMAN; HYDRONEPHROSIS; INFECTION RISK; KIDNEY SCAR; MICTURITION; PATIENT COMPLIANCE; RECURRENT INFECTION; URETEROPELVIC JUNCTION OBSTRUCTION; URINARY TRACT INFECTION; VESICOURETERAL REFLUX;

ANTI-INFECTIVE AGENTS, URINARY; ANTIBIOTIC PROPHYLAXIS; CHILD; CIRCUMCISION, MALE; HUMANS; MALE; RECURRENCE; RISK FACTORS; TREATMENT OUTCOME; URINARY TRACT INFECTIONS; VESICO-URETERAL REFLUX;

EID: 79955833873     PISSN: 15272737     EISSN: 15346285     Source Type: Journal    
DOI: 10.1007/s11934-010-0164-y     Document Type: Article

References (34)

1. J Wan R Kaplinsky SP Greenfield 1995 Toilet habits of children evaluated for urinary tract infection J Urol 154 797 799 7609183 10.1016/S0022-5347(01) 67167-2 1:STN:280:DyaK2MzjtlCiuw%3D%3D
2. W Farhat DJ Bagli G Capolicchio, et al. 2000 The dysfunctional voiding scoring system: quantitative standardization of dysfunctional voiding symptoms in children J Urol 164 1011 1015 10958730 10.1016/S0022-5347(05)67239-4 1:STN:280:DC%2BD3cvjtVWjsQ%3D%3D (Pubitemid 30637563)
3. PH Conway A Cnaan T Zaoutis, et al. 2007 Recurrent urinary tract infections in children: risk factors and association with prophylactic antimicrobials JAMA 298 179 186 17622599 10.1001/jama.298.2.179 1:CAS:528:DC%2BD2sXnslSjtbo%3D (Pubitemid 47057764)
4. JC Craig JM Simpson GJ Williams, et al. 2009 Antibiotic prophylaxis and recurrent urinary tract infection in children NEJM 361 1748 1759 19864673 10.1056/NEJMoa0902295 1:CAS:528:DC%2BD1MXhtlajsLfI
5. G Williams JC Craig 2009 Prevention of recurrent urinary tract infection in children Curr Op Inf Dis 22 72 76 10.1097/QCO.0b013e328320a885 This was a large prospective study of children with and without reflux, showing a slight advantage to prophylaxis
6. R Mori A Fitzgerald C Williams, et al. 2009 Antibiotic prophylaxis for children at risk of developing urinary tract infection: a systemic review Acta Paed 98 1781 1786 10.1111/j.1651-2227.2009.01433.x
7. G Montini L Rigon P Zuchetta, et al. 2007 Prophylaxis after first febrile urinary tract infection in children? A multicenter, randomized, controlled noninferiority trial Pediatrics 122 1064 1071 10.1542/peds.2007-3770
8. Williams G, Wei L, Lee A, et al.: Long term antibiotics for preventing recurrent urinary tract infection in children (review). Cochrane Collaboration in the Cochrane Library 2009, John Wiley & Sons, Ltd pp 1-28.
9. S Cascio E Colhoun P Puri 2000 Bacterial colonization of the prepuce in boys with vesicoureteral reflux who receive antibiotic prophylaxis J Peds 139 160 162 10.1067/mpd.2001.115017 (Pubitemid 32614006)
10. N Fisch S Ashkenazi M Davidowitz 2009 Prophylactic antibiotics and evaluation scheme following febrile urinary tract infection in children: a nationwide Israeli survey IMAJ 11 677 682 20108555
11. I Chevalier G Benoit M Gauthier, et al. 2008 Antibiotic prophylaxis for childhood urinary tract infection: a national survey J Ped Child Health 44 572 578 10.1111/j.1440-1754.2008.01385.x
12. CH Cheng T Ming-Horng H Yhu-Chering, et al. 2008 Antibiotic resistance patterns of community-acquired urinary tract infections in children with vesicoureteral reflux receiving prophylactic antibiotic therapy Peds 122 1212 1217 10.1542/peds.2007-2926
13. SJ Lee YH Shim SJ Cho, et al. 2007 Probiotics prophylaxis in children with persistent primary vesicoureteral reflux Pediatr Nephrol 22 1315 1320 17530295 10.1007/s00467-007-0507-1 (Pubitemid 47054922)
14. SP Greenfield M Ng J Wan 1997 Experience with vesicoureteral reflux in children: clinical characteristics J Urol 158 574 577 9224365 10.1016/S0022-5347(01)64556-7 1:STN:280:DyaK2szmslKlsA%3D%3D (Pubitemid 27327721)
15. CS Cooper BI Chung AJ Kirsch, et al. 2000 The outcome of stopping prophylactic antibiotics in older children with vesicoureteral reflux J Urol 163 269 273 10604374 10.1016/S0022-5347(05)68034-2 1:STN:280: DC%2BD3c%2FmslylsQ%3D%3D
16. EH Garin F Olavarria NV Garcia, et al. 2006 Clinical significance of primary vesicoureteral reflux and urinary antibiotic prophylaxis after acute pyelonephritis: a multicenter, randomized, controlled study Peds 117 626 632 10.1542/peds.2005-1362 (Pubitemid 46063202)
17. G Roussey-Kesler V Gadjos N Idres, et al. 2008 Antibiotic prophylaxis for the prevention of recurrent urinary tract infection in children with low grade vesicoureteral reflux: results from a prospective randomized study J Urol 179 674 679 18082208 10.1016/j.juro.2007.09.090 1:STN:280:DC%2BD1c%2Fjs1ehug%3D%3D
18. P Brandstrom E Esbjorner M Herthelius, et al. 2010 The Swedish reflux trial in children: I Study design and study population characteristics J Urol 184 274 279 20478580 10.1016/j.juro.2010.01.055
19. P Brandstrom E Esbjorner M Herthelius, et al. 2010 The Swedish reflux trial in children: III. Urinary tract infection pattern J Urol 184 286 291 20488494 10.1016/j.juro.2010.01.061 The authors studied a well-defined group of children with grade 3 or 4 reflux who had a significant decrease in recurrent infections on prophylaxis
20. P Brandstrom T Neveus R Sixt, et al. 2010 The Swedish reflux trial in children: IV. Renal Damage J Urol 184 292 297 20494369 10.1016/j.juro.2010.01. 060 The authors studied a well-defined group of children with grade 3 or 4 reflux who had significant prevention of new renal scarring while on prophylaxis
21. U Sillen P Brandstrom U Jodal, et al. 2010 The Swedish reflux trial in children: V. Bladder dysfunction J Urol 184 298 304 20488486 10.1016/j.juro.2010.03.063
22. A Al-Sayyad J Pike MP Leonard 2005 Can prophylactic antibiotics safely be discontinued in children with vesicoureteral reflux? J Urol 174 1587 1589 16148658 10.1097/01.ju.0000176336.67905.c7 (Pubitemid 41318631)
23. H Georgaki-Angelaki S Kostaridou GL Daikos, et al. 2005 Long-term follow-up of children with vesicoureteral reflux with and without antibiotic prophylaxis Scand J Inf Dis 37 842 845 10.1080/00365540500279918 1:STN:280:DC%2BD2MnivVSnug%3D%3D
24. DM Kitchens A Herndon DB Joseph 2010 Outcome after discontinuing prophylactic antibiotics in children with persistent vesicoureteral reflux J Urol 184 1594 1597 20728116 10.1016/j.juro.2010.04.020
25. CA Peters SJ Skoog BS Arant, et al. 2010 Summary of the AUA guideline on management of primary vesicoureteral reflux in children J Urol 184 1134 1144 20650499 10.1016/j.juro.2010.05.065 This is the most comprehensive meta-analysis of the literature, with well-reasoned conclusions regarding therapy
26. R Keren MA Carpenter A Hoberman, et al. 2008 Rationale and design issues of the randomized intervention for children with vesicoureteral reflux (RIVUR) study Peds 5 Suppl 5240 5250 This article provides a comprehensive discussion of the RIVUR trial and its aims
27. SP Greenfield RW Chesney M Carpenter, et al. 2008 Vesicoureteral reflux: the RIVUR study and the way forward J Urol 179 405 407 18076937 10.1016/j.juro.2007.10.100 This article provides a succinct analysis of the shortcomings of the current literature and a brief description of the RIVUR trial
28. HL Copp CP Nelson LD Shortliffe, et al. 2010 Compliance with antibiotic prophylaxis in children with vesicoureteral reflux: results from a national pharmacy claims data base J Urol 183 1994 2000 20303526 10.1016/j.juro.2010.01. 036
29. J Wan SP Greenfield M Talley, et al. 1996 An analysis of social and economic factors associated with followup of patients with vesicoureteral reflux J Urol 156 668 672 8683756 10.1016/S0022-5347(01)65780-X 1:STN:280: DyaK283ovFCitg%3D%3D (Pubitemid 126444899)
30. Ogan K, Pohl H, Carlson D, et al.: Parental preferences in the management of vesicoureteral reflux. J Urol 2001, 240-243. (Pubitemid 32565404)
31. M Woodward D Frank 2002 Postnatal management of antenatal hydronephrosis BJU Int 89 149 156 11849184 10.1046/j.1464-4096.2001.woodward.2578.x 1:STN:280:DC%2BD387hsVyjug%3D%3D (Pubitemid 34117750)
32. JH Lee HS Choi JK Kim, et al. 2008 Nonrefluxing neonatal hydronephrosis and the risk of urinary tract infection J Urol 179 1524 1528 18295269 10.1016/j.juro.2007.11.090
33. CC Roth JM Hubanks BC Bright, et al. 2009 Occurence of urinary tract infection in children with significant upper urinary tract obstruction Urology 73 74 78 18619654 10.1016/j.urology.2008.05.021 The authors studied a well-defined group of infants with prenatally diagnosed UPJO and UVJO who were followed off prophylaxis
34. Greenfield SP, Deshmukh S, Williot P: Prenatally detected primary ureterovesical junction obstruction: are prophylactic antibiotics necessary? Presented at the Urology Section, American Academy of Pediatrics, Washington, DC October 2009.