The Swedish Reflux Trial in Children: IV. Renal Damage

Journal of Urology

Volumn 184, Issue 1, 2010, Pages 292-297

  Brandström, Per ^a   Nevéus, Tryggve ^b   Sixt, Rune ^a   Stokland, Eira ^a   Jodal, Ulf ^a   Hansson, Sverker ^a  

^a QUEEN SILVIA CHILDREN'S HOSPITAL   (Sweden)

^b UNIVERSITY CHILDREN S HOSPITAL   (Sweden)

Author keywords

cicatrix; fever; kidney; urinary tract infections; vesico ureteral reflux

Indexed keywords

ANTIBIOTIC AGENT; DEXTRANOMER; HYALURONIC ACID; SUCCIMER TC 99M;

AGE DISTRIBUTION; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC THERAPY; ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COURSE EVALUATION; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOSCOPIC THERAPY; FEMALE; FEVER; FOLLOW UP; HUMAN; KIDNEY INJURY; KIDNEY SCINTISCANNING; MAJOR CLINICAL STUDY; MALE; MICTURITION CYSTOURETHROGRAPHY; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; URINARY TRACT INFECTION; VESICOURETERAL REFLUX;

ANTIBIOTIC PROPHYLAXIS; ENDOSCOPY; FEMALE; FEVER; HUMANS; INFANT; KIDNEY DISEASES; KIDNEY FUNCTION TESTS; MALE; POPULATION SURVEILLANCE; PROSPECTIVE STUDIES; RECURRENCE; SEX FACTORS; SWEDEN; TECHNETIUM TC 99M DIMERCAPTOSUCCINIC ACID; URINARY TRACT INFECTIONS; UROGRAPHY; VESICO-URETERAL REFLUX;

EID: 77953120600     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2010.01.060     Document Type: Article

References (23)

1. Hodson C.J., and Edwards D. Chronic pyelonephritis and vesico-ureteric reflex. Clin Radiol 11 (1960) 219 2
2. Bailey R.R. The relationship of vesico-ureteric reflux to urinary tract infection and chronic pyelonephritis-reflux nephropathy. Clin Nephrol 1 (1973) 132
3. Rushton H.G., Majd M., Jantausch B., et al. Renal scarring following reflux and nonreflux pyelonephritis in children: evaluation with 99mtechnetium-dimercaptosuccinic acid scintigraphy. J Urol 147 (1992) 1327
4. Jakobsson B., Berg U., and Svensson L. Renal scarring after acute pyelonephritis. Arch Dis Child 70 (1994) 111
5. Stokland E., Hellström M., Jacobsson B., et al. Renal damage one year after first urinary tract infection: role of dimercaptosuccinic acid scintigraphy. J Pediatr 129 (1996) 815
6. Preda I., Jodal U., Sixt R., et al. Normal dimercaptosuccinic acid scintigraphy makes voiding cystourethrography unnecessary after urinary tract infection. J Pediatr 151 (2007) 581
7. Goldman M., Bistritzer T., Horne T., et al. The etiology of renal scars in infants with pyelonephritis and vesicoureteral reflux. Pediatr Nephrol 14 (2000) 385
8. Wennerström M., Hansson S., Jodal U., et al. Primary and acquired renal scarring in boys and girls with urinary tract infection. J Pediatr 136 (2000) 30
9. Craig J.C., Irwig L.M., Knight J.F., et al. Does treatment of vesicoureteric reflux in childhood prevent end-stage renal disease attributable to reflux nephropathy?. Pediatrics 105 (2000) 1236
10. Fanos V., and Cataldi L. Antibiotics or surgery for vesicoureteric reflux in children. Lancet 364 (2004) 1720
11. Brandström P., Esbjörner E., Herthelius M., et al. The Swedish Reflux Trial in Children: I. Study design and study population characteristics. J Urol 184 (2010) 274
12. Pocock S.J., and Simon R. Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics 31 (1975) 103
13. Lebowitz R.L., Olbing H., Parkkulainen K.V., et al. International system of radiographic grading of vesicoureteric reflux. International Reflux Study in Children. Pediatr Radiol 15 (1985) 105
14. Piepsz A., Colarinha P., Gordon I., et al. Guidelines on 99mTc-DMSA scintigraphy in children. Eur J Nucl Med 28 (2001) 37
15. Stokland E., Jodal U., Sixt R., et al. Uncomplicated duplex kidney and DMSA scintigraphy in children with urinary tract infection. Pediatr Radiol 37 (2007) 826
16. Piepsz A., Tamminen-Möbius T., Reiners C., et al. Five-year study of medical or surgical treatment in children with severe vesico-ureteral reflux dimercaptosuccinic acid findings. International Reflux Study Group in Europe. Eur J Pediatr 157 (1998) 753
17. Brandström P., Esbjörner E., Herthelius M., et al. The Swedish Reflux Trial in Children: III. Urinary tract infection pattern. J Urol 184 (2010) 286
18. Winberg J., Andersen H.J., Bergström T., et al. Epidemiology of symptomatic urinary tract infection in childhood. Acta Paediatr Scand 252 suppl. (1974) 1
19. Hansson S., Bollgren I., Esbjörner E., et al. Urinary tract infections in children below two years of age: a quality assurance project in Sweden. The Swedish Pediatric Nephrology Association. Acta Paediatr 88 (1999) 270
20. Garin E.H., Olavarria F., Garcia Nieto V., et al. Clinical significance of primary vesicoureteral reflux and urinary antibiotic prophylaxis after acute pyelonephritis: a multicenter, randomized, controlled study. Pediatrics 117 (2006) 626
21. Pennesi M., Travan L., Peratoner L., et al. Is antibiotic prophylaxis in children with vesicoureteral reflux effective in preventing pyelonephritis and renal scars?. A randomized, controlled trial. Pediatrics 121 (2008) e1489
22. Montini G., Rigon L., Zucchetta P., et al. Prophylaxis after first febrile urinary tract infection in children?. A multicenter, randomized, controlled, noninferiority trial. Pediatrics 122 (2008) 1064
23. Keren R., Carpenter M.A., Hoberman A., et al. Rationale and design issues of the Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR) study. Pediatrics 122 suppl. (2008) S240