Maintenance of aerobic metabolism increases immunoisolated islet survival

Islets

Volumn 3, Issue 3, 2011, Pages 89-92

  Stagner, John I ^a   Seelan, Ratnam S ^b   Parthasarathy, Ranga N ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

Cytoglobin; Hypoxia; Immunoisolation; Islets; Islets of langerhans

Indexed keywords

CYTOGLOBIN;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL FUNCTION; CELL SURVIVAL; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; HOLLOW FIBER; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SYNTHESIS; MALE; NONHUMAN; PANCREAS ISLET CELL; PANCREAS ISLET TRANSPLANTATION; PLASMID; RAT;

AEROBIOSIS; ANIMALS; BLOOD GLUCOSE; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; GLOBINS; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; LEAST-SQUARES ANALYSIS; MALE; RATS; RATS, INBRED LEW; TRANSFECTION;

EID: 79955830322     PISSN: 19382014     EISSN: 19382022     Source Type: Journal    
DOI: 10.4161/isl.3.3.15404     Document Type: Article

References (26)

1. Beck J, Angus R, Madsen B, Britt D, Vernon B, Nguyen KT. Islet encapsulation: strategies to enhance islet cell functions. Tiss Eng 2007; 13:589-99. (Pubitemid 46579884)
2. De Vos P, Faas MM, Strand B, Calafiore R. Alginate-based microcapsules for immunoisolation of pancreatic islets. Biomaterials 2006; 27:5603-17. (Pubitemid 44177795)
3. Mullen Y, Maruyama M, Smith CV. Current progress and perspectives in immunoisolated islet transplantation. J Hepatobiliary Pancreat Surg 2000; 7:347-57.
4. Wilson JT, Chaikof EL. Challenges and emerging technologies in the immunoisolation of cells and tissues. Adv Drug Deliv Rev 2008; 60:124-45. (Pubitemid 350245691)
5. Fago A, Hundahl C, Dewilde S, Moens L, Weber RE. Functional properties of vertebrate neuroglobulin and cytoglobin. Comp Biochem Physiol 2005; 141:188.
6. Burmester T, Ebner B, Weich B, Hankeln T. Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues. Molec Biol and Evolution 2002; 19:416-21. (Pubitemid 34289416)
7. Hamdane D, Kiger L, Dewilde S, Green BN, Pesca A, Uzan J, et al. The redox state of the cell regulates the ligand binding affinity of human neuroglobin and cytoglobin. J Biol Chem 2003; 278:51713-2.
8. Ascenzi P, Bocedi A, de Sanctis D, Pesce A, Bolognesi M, Marden MC, et al. Neuroglobin and cytoglobin. Two new entries in the hemoglobin superfamily. Biochem Molec Biol Education 2004; 32:305-13.
9. Fordel E, Geuens E, Dewilde S, Rottiers P, Carmeliet P, Grooten J,et al. Cytoglobin expression is upregulated in all tissues upon hypoxia an in vitro and in vivo study by quantitative real-time PCR. Biochem Biophys Res Comm 2004; 319:342-8.
10. Stagner JI, Seelan RS, Parthasarathy RN, White K. Reduction of ischemic cell death in cultured islets of Langerhans by the induction of cytoglobin. Islets 2009; 1:50-4.
11. Bloch K. Papismedov E. Immobilized microalgal cells as an oxygen supply system for encapsulated pancreatic islets: a feasibility study. Art Org 2006; 30:715-8. (Pubitemid 44289699)
12. Bloch K, Papismedov E, Yavriyants K, Vorobeychik M, Beer S, Vardi P. Photosynthetic oxygen generator for bioartificial pancreas. Tiss Eng 2006; 12:337-44.
13. Tilakaratne HK, Yang B, Hunter SK, Andracki ME, Rodgers VGJ. Can myoglobin expression in pancreatic beta cells improve insulin secretion under hypoxia? an exploratory study with transgenic porcine islets. Art Org 2007; 31:521-31. (Pubitemid 46961705)
14. Chae SY, Kim SW, Bae YH. Effect of cross-linked hemoglobin in functionality and viability of microencapsulated pancreatic islets. Tiss Eng 2002; 379-94. (Pubitemid 34747796)
15. Carlsson PO, Kiuru A, Nordin A, Olsson R. Microdialysis measurements demonstrate a shift to nonoxidative glucose metabolism in rat pancreatic islets transplanted beneath the renal capsule. Surgery 2002; 132:487-94. (Pubitemid 35157780)
16. Carlsson PO, Palm F, Andersson A, Liss P. Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the transplant site. Diabetes 2001; 50:489-95. (Pubitemid 32195212)
17. Li X, Chen H, Epstein PN. Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species. J Biol Chem 2004; 279:765-71. (Pubitemid 38044882)
18. Guzy RD, Schumaker PT. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp Physiol 2006; 91:5807-19.
19. Kramer RS, Pearlstein RD. Reversible uncoupling of oxidative phosphorylation at low oxygen tension. Proc Natl Acad Sci USA 1983; 80:5807-11. (Pubitemid 14227566)
20. Nath KA, Croatt AJ, Hostetter TH. Oxygen consumption and oxidant stress in surviving nephrons. Am J Physiol Renal Physiol 1990; 258:1354-62.
21. Fago A, Hundahl C, Malte H, Weber RE. Functional properties of neuroglobin and cytoglobin. Insights into the ancestral physiological roles of globins. IUBMB Life 2004; 56:689-96.
22. Taylor CT. Mitochondria and cellular oxygen sensing in the HIF pathway. Biochem J 2008; 409:19-26.
23. Kaelin WG. Proline hydroxylation and gene expression. Annu Rev Biochem 2005; 74:115-28.
24. 2-sensitive adrenomedullary chromaffin cell line. Am J Physiol Cell Physiol 2008; 294:1300-2.
25. Metzen E, Ratcliffe PJ. HIF hydroxylation and cellular oxygen sensing. Biol Chem 2004; 358:223-30. (Pubitemid 38679067)
26. Liu LX, Lu H, Luo Y, Date T, Belanger AJ, Vincent KA, et al. Stabilization of vascular endothelial growth factor by mRNA by hypoxia-inducible factor-1. Biochem Biophys Res Commun 2002; 291:908-14. (Pubitemid 34694361)