Can myoglobin expression in pancreatic beta cells improve insulin secretion under hypoxia? An exploratory study with transgenic porcine islets

Artificial Organs

Volumn 31, Issue 7, 2007, Pages 521-531

  Tilakaratne, Himantha Kushanie ^a,b   Yang, Baoli ^b   Hunter, Stephen K ^a,b   Andracki, Mark E ^b   Rodgers, Victor G J ^a,b,c  

^a University of Iowa   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c University of California Riverside   (United States)

Author keywords

Bioartificial pancreas; Diabetes; Facilitated transport; Hypoxic; Myoglobin; Oxygen; Transgenic porcine islets

Indexed keywords

INSULIN; OXYGEN; PHYSIOLOGY;

BIO-ARTIFICIAL PANCREAS; EXPLORATORY STUDIES; FACILITATED TRANSPORT; GREEN FLUORESCENT PROTEIN; HYPOXIC; INSULIN SECRETION; MYOGLOBIN; PANCREATIC BETA CELLS; TRANSGENIC PORCINE ISLET; TRANSGENICS;

VIRUSES;

ADENOVIRUS VECTOR; GLUCOSE; GREEN FLUORESCENT PROTEIN; INSULIN; MYOGLOBIN;

ANIMAL CELL; ARTICLE; ARTIFICIAL PANCREAS; CELL SURVIVAL; CONTROLLED STUDY; EXPLORATORY RESEARCH; GENETIC TRANSFECTION; HYPOXIA; INSULIN RELEASE; INSULIN RESPONSE; MUSCLE CELL; NONHUMAN; OXYGEN TENSION; OXYGEN TRANSPORT; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; TRANSGENIC ANIMAL;

SUS;

EID: 34250748468     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2007.00416.x     Document Type: Article

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