-
1
-
-
58149120422
-
American heart association statistics committee and stroke statistics subcommittee
-
Heart disease and stroke statistics-2010 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
-
Carnethon M, Rosamond W, Furie K, et al. American heart association statistics committee and stroke statistics subcommittee. Heart disease and stroke statistics-2010 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2010;121:e46-215
-
(2010)
Circulation
, vol.121
-
-
Carnethon, M.1
Rosamond, W.2
Furie, K.3
-
2
-
-
77951624456
-
The critical link of hypervolemia and hyponatremia in heart failure and the potential role of arginine vasopressin antagonists
-
Ghali JK, Tam SW. The critical link of hypervolemia and hyponatremia in heart failure and the potential role of arginine vasopressin antagonists. J Card Fail 2010;16:419-31
-
(2010)
J Card Fail
, vol.16
, pp. 419-431
-
-
Ghali, J.K.1
Tam, S.W.2
-
3
-
-
68749103375
-
Mortality after hospitalization with mild, moderate, and severe hyponatremia
-
Waikar SS, Mount DB, Curhan GC. Mortality after hospitalization with mild, moderate, and severe hyponatremia. Am J Med 2009;122:857-65
-
(2009)
Am J Med
, vol.122
, pp. 857-865
-
-
Waikar, S.S.1
Mount, D.B.2
Curhan, G.C.3
-
4
-
-
76149146021
-
Impact of hospital-associated hyponatremia on selected outcomes
-
Wald R, Jaber BL, Price LL, et al. Impact of hospital-associated hyponatremia on selected outcomes. Arch Intern Med 2010;170:294-302
-
(2010)
Arch Intern Med
, vol.170
, pp. 294-302
-
-
Wald, R.1
Jaber, B.L.2
Price, L.L.3
-
5
-
-
67649781921
-
Mild hyponatremia carries a poor prognosis in community subjects
-
Sajadieh A, Binici Z, Mouridsen MR, et al. Mild hyponatremia carries a poor prognosis in community subjects. Am J Med 2009;122:679-86
-
(2009)
Am J Med
, vol.122
, pp. 679-686
-
-
Sajadieh, A.1
Binici, Z.2
Mouridsen, M.R.3
-
7
-
-
52949105320
-
Mechanisms, risks, and new treatment options for hyponatremia
-
Ghali JK. Mechanisms, risks, and new treatment options for hyponatremia. Cardiology 2008;111:147-57
-
(2008)
Cardiology
, vol.111
, pp. 147-157
-
-
Ghali, J.K.1
-
8
-
-
0029797671
-
Cardiac sympathetic afferent reflex in dogs with congestive heart failure
-
Wang W, Zucker IH. Cardiac sympathetic afferent reflex in dogs with congestive heart failure. Am J Physiol 1996;271:R751-6
-
(1996)
Am J Physiol
, vol.271
-
-
Wang, W.1
Zucker, I.H.2
-
9
-
-
33745726360
-
Is asymptomatic hyponatremia really asymptomatic?
-
Decaux G. Is asymptomatic hyponatremia really asymptomatic? Am J Med 2006;119(7A):S79-82
-
(2006)
Am J Med
, vol.119
, Issue.7 A
-
-
Decaux, G.1
-
10
-
-
30944460468
-
Mild chronic hyponatremia is associated with falls, unsteadiness and attention deficits
-
Renneboog B, Vendemergel X, Manto MN, et al. Mild chronic hyponatremia is associated with falls, unsteadiness and attention deficits. Am J Med 2006;119:71e1-8
-
(2006)
Am J Med
, vol.119
-
-
Renneboog, B.1
Vendemergel, X.2
Manto, M.N.3
-
11
-
-
0023708559
-
Role of vasopressin in cardiovascular regulation
-
Share L. Role of vasopressin in cardiovascular regulation. Physiol Rev 1988;4:1248-84
-
(1988)
Physiol Rev
, vol.4
, pp. 1248-1284
-
-
Share, L.1
-
12
-
-
0030993733
-
Interaction of osmotic and nonosmotic stimuli in regulation of vasopressin secretion in hypoosmolar state of man
-
Kamoi K, Ishibashi M, Yamaji T. Interaction of osmotic and nonosmotic stimuli in regulation of vasopressin secretion in hypoosmolar state of man. Endocr J 1997;44:311-17 (Pubitemid 27229877)
-
(1997)
Endocrine Journal
, vol.44
, Issue.2
, pp. 311-317
-
-
Kamoi, K.1
Ishibashi, M.2
Yamaji, T.3
-
13
-
-
34249047454
-
The syndrome of inappropriate antidiuresis
-
DOI 10.1056/NEJMcp066837
-
Ellison DH, Berl T. Clinical practice. The syndrome of inappropriate antidiuresis. N Engl J Med 2007;356:2064-72 (Pubitemid 46789896)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.20
, pp. 2064-2072
-
-
Ellison, D.H.1
Berl, T.2
-
14
-
-
0022547140
-
Arginine vasopressin and the renal response to water loading in congestive heart failure
-
DOI 10.1016/0002-9149(86)90065-2
-
Goldsmith SR, Francis GS, Cowley AW. Arginine vasopressin and the renal response to water loading in congestive heart failure. Am J Cardiol 1986;58:295-9 (Pubitemid 16052721)
-
(1986)
American Journal of Cardiology
, vol.58
, Issue.3
, pp. 295-299
-
-
Goldsmith, S.R.1
Francis, G.S.2
Cowley Jr., A.W.3
-
15
-
-
0021279294
-
Role of antidiuretic hormone in impaired water excretion of patients with congestive heart failure
-
Pruszczynski W, Vahanian A, Ardaillou R, et al. Role of antidiuretic hormone in impaired water excretion of patients with congestive heart failure. J Clin Endocrinol Metab 1984;58:599-605 (Pubitemid 14137249)
-
(1984)
Journal of Clinical Endocrinology and Metabolism
, vol.58
, Issue.4
, pp. 599-605
-
-
Pruszczynski, W.1
Vahanian, A.2
Ardaillou, R.3
Acar, J.4
-
16
-
-
0022623287
-
Modulation of plasma and platelet vasopressin by cardiac function in patients with heart failure
-
Bichet DG, Kortas C, Mettauer B, et al. Modulation of plasma and platelet vasopressin by cardiac function in patients with heart failure. Kidney Int 1986;29:1188-96 (Pubitemid 16094232)
-
(1986)
Kidney International
, vol.29
, Issue.6
, pp. 1188-1196
-
-
Bichet, D.G.1
Kortas, C.2
Mettauer, B.3
-
17
-
-
0025153828
-
Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the studies of left ventricular dysfunction (SOLVD)
-
Francis GS, Benedict C, Johnstone DE, et al. Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD). Circulation 1990;82:1724-9 (Pubitemid 20367975)
-
(1990)
Circulation
, vol.82
, Issue.5
, pp. 1724-1729
-
-
Francis, G.S.1
Benedict, C.2
Johnstone, D.E.3
Kirlin, P.C.4
Nicklas, J.5
Liang, C.6
Kubo, S.H.7
Rudin-Toretsky, E.8
Yusuf, S.9
-
18
-
-
33745712365
-
Water and sodium retention in edematous disorder: Role of vasopressin and aldosterone
-
Schrier RW. Water and sodium retention in edematous disorder: role of vasopressin and aldosterone. Am J Med 2006;119:S47-53
-
(2006)
Am J Med
, vol.119
-
-
Schrier, R.W.1
-
19
-
-
0024319728
-
Biphasic forearm vascular responses to intraarterial arginine vasopressin
-
Suzuki S, Takeshita A, Imaizumi T, et al. Biphasic forearm vascular responses to intraarterial arginine vasopressin. J Clin Invest 1989;84:427-34 (Pubitemid 19196972)
-
(1989)
Journal of Clinical Investigation
, vol.84
, Issue.2
, pp. 427-434
-
-
Suzuki, S.1
Takeshita, A.2
Imaizumi, T.3
Hirooka, Y.4
Yoshida, M.5
Ando, S.6
Nakamura, M.7
-
20
-
-
0027389918
-
Early diagnosis of ectopic arginine vasopressin secretion
-
Coyle S, Penney MD, Masters PW, et al. Early diagnosis of ectopic arginine vasopressin secretion. Clin Chem 1993;39:152-4 (Pubitemid 23034978)
-
(1993)
Clinical Chemistry
, vol.39
, Issue.1
, pp. 152-154
-
-
Coyle, S.1
Penney, M.D.2
Masters, P.W.3
Walker, B.E.4
-
21
-
-
0031650278
-
Molecular pharmacology of human vasopressin receptors
-
Thibonnier M, Conarty DM, Preston JA, et al. Molecular pharmacology of human vasopressin receptors. Adv Exp Med Biol 1998;449:251-76 (Pubitemid 28566397)
-
(1998)
Advances in Experimental Medicine and Biology
, vol.449
, pp. 251-276
-
-
Thibonnier, M.1
Conarty, D.M.2
Preston, J.A.3
Wilkins, P.L.4
Berti-Mattera, L.N.5
Mattera, R.6
-
22
-
-
34247259624
-
Therapeutic potential of vasopressin receptor antagonists
-
Ali F, Guglin M, Vaitkevicius P, et al. Therapeutic potential of vasopressin receptor antagonists. Drugs 2007;67:847-58 (Pubitemid 46607386)
-
(2007)
Drugs
, vol.67
, Issue.6
, pp. 847-858
-
-
Ali, F.1
Guglin, M.2
Vaitkevicius, P.3
Ghali, J.K.4
-
23
-
-
0035882327
-
Antidiuretic action of vasopressin: Quantitative aspects and interaction between V1a and V2 receptor-mediated effects
-
DOI 10.1016/S0008-6363(01)00328-5, PII S0008636301003285
-
Bankir L. Antidiuretic action of vasopressin: quantitative aspects and interaction between V1A and V2 receptor-mediated effects. Cardiovasc Res 2001;51:372-90 (Pubitemid 32718586)
-
(2001)
Cardiovascular Research
, vol.51
, Issue.3
, pp. 372-390
-
-
Bankir, L.1
-
24
-
-
17444400790
-
Current treatments and novel pharmacologic treatments for hyponatremia in congestive heart failure
-
DOI 10.1016/j.amjcard.2005.03.004, Hyponatemia in Congestive Heart Failure
-
Goldsmith SR. Current treatments and novel pharmacologic treatments for hyponatremia in congestive heart failure. Am J Cardiol 2005;95:14B-23B (Pubitemid 40545928)
-
(2005)
American Journal of Cardiology
, vol.95
, Issue.9 SUPPL. 1
-
-
Goldsmith, S.R.1
-
25
-
-
0033965154
-
2-receptor antagonist OPC-41061 and the loop diuretic furosemide alone and in combination in rats
-
Hirano T, Yamamura Y, Nakamura S, et al. Effects of the V2-receptor antagonist OPC-41061 and the loop diuretic furosemide alone and in combination in rats. J Pharmacol Exp Ther 2000;292:288-94 (Pubitemid 30026383)
-
(2000)
Journal of Pharmacology and Experimental Therapeutics
, vol.292
, Issue.1
, pp. 288-294
-
-
Hirano, T.1
Yamamura, Y.2
Nakamura, S.3
Onogawa, T.4
Mori, T.5
-
26
-
-
0018947010
-
Plasma demeclocycline levels and nephrotoxicity. Correlation in hyponatremic cirrhotic patients
-
DOI 10.1001/jama.243.24.2513
-
Miller PD, Linas SL, Schrier RW. Plasma demeclocycline levels and nephrotoxicity: correlation in hyponatremic cirrhotic patients. JAMA 1980;243:2513-15 (Pubitemid 10039244)
-
(1980)
Journal of the American Medical Association
, vol.243
, Issue.24
, pp. 2513-2515
-
-
Miller, P.D.1
Linas, L.S.2
Schrier, R.W.3
-
28
-
-
0026533435
-
Characterization of a novel aquaretic agent, OPC-31260, as an orally effective, nonpeptide vasopressin V2 receptor antagonist
-
Yamamura Y, Ogawa H, Yamashita H, et al. Characterization of a novel aquaretic agent, OPC-31260, as an orally effective, nonpeptide vasopressin V2 receptor antagonist. Br J Pharmacol 1992;105:787-91
-
(1992)
Br J Pharmacol
, vol.105
, pp. 787-791
-
-
Yamamura, Y.1
Ogawa, H.2
Yamashita, H.3
-
29
-
-
0009689526
-
2 receptor antagonist
-
Serradeil-Le Gal C, Lacour C, Valette G, et al. Characterization of SR 121463A, a highly potent and selective orally active vasopressin V2 receptor antagonist. J Clin Invest 1996;98:2729-38 (Pubitemid 26427399)
-
(1996)
Journal of Clinical Investigation
, vol.98
, Issue.12
, pp. 2729-2738
-
-
Serradeil-Le Gal, C.1
Lacour, C.2
Valette, G.3
Garcia, G.4
Foulon, L.5
Galindo, G.6
Bankir, L.7
Pouzet, B.8
Guillon, G.9
Barberis, C.10
Chicot, D.11
Jard, S.12
Vilain, P.13
Garcia, C.14
Marty, E.15
Raufaste, D.16
Brossard, G.17
Nisato, D.18
Maffrand, J.P.19
Le Fur, G.20
more..
-
30
-
-
0030770540
-
2 receptor antagonist, in vitro and in vivo
-
Tahara A, Tomura Y, Wada KI, et al. Pharmacological profile of YM087, a novel potent nonpeptide vasopressin V1A and V2 receptor antagonist, in vitro and in vivo. J Pharmacol Exp Ther 1997;282:301-8 (Pubitemid 27425555)
-
(1997)
Journal of Pharmacology and Experimental Therapeutics
, vol.282
, Issue.1
, pp. 301-308
-
-
Tahara, A.1
Tomura, Y.2
Wada, K.-I.3
Kusayama, T.4
Tsukada, J.5
Takanashi, M.6
Yatsu, T.7
Uchida, W.8
Tanaka, A.9
-
31
-
-
17344390052
-
2 receptor antagonist
-
Chan PS, Couplet J, Park HC, et al. VPA-985, a nonpeptide orally active and selective vasopressin V2 receptor antagonist. Adv Exp Med Biol 1998;449:439-43 (Pubitemid 28566418)
-
(1998)
Advances in Experimental Medicine and Biology
, vol.449
, pp. 439-443
-
-
Chan, P.S.1
Coupet, J.2
Park, H.C.3
Lai, F.4
Hartupee, D.5
Cervoni, P.6
Dusza, J.P.7
Albright, J.D.8
Ru, X.9
Mazandarani, H.10
Tanikella, T.11
Shepherd, C.12
Ochalski, L.13
Bailey, T.14
Yeung, T.15
Lock, W.16
Ning, X.17
Taylor, J.R.18
Spinelli, W.19
-
32
-
-
14444285742
-
2 receptors [2]
-
DOI 10.1021/jm980179c
-
Albright JD, Reich MF, Delos Santos EG, et al. 5-Fluoro-2-methyl-N-[4- (5H-pyrrolo [2,1-c]-[1, 4] benzodiazepin-10(11H)-ylcarbonyl)-3-chlorophenyl] benzamide (VPA-985): an orally active arginine vasopressin antagonist with selectivity for V2 receptors. J Med Chem 1998;41:2442-4 (Pubitemid 28321894)
-
(1998)
Journal of Medicinal Chemistry
, vol.41
, Issue.14
, pp. 2442-2444
-
-
Albright, J.D.1
Reich, M.F.2
Delos Santos, E.G.3
Dusza, J.P.4
Sum, F.-W.5
Venkatesan, A.M.6
Coupet, J.7
Chan, P.S.8
Ru, X.9
Mazandarani, H.10
Bailey, T.11
-
33
-
-
4243323286
-
In vitro pharmacology of VPA-985, a non-peptide V2 selective vasopressin antagonist
-
Park CH, Lock YW, Tanikella TK, et al. In vitro pharmacology of VPA-985, a non-peptide V2 selective vasopressin antagonist. J Am Soc Nephrol 1998;9:A0120
-
(1998)
J Am Soc Nephrol
, vol.9
-
-
Park, C.H.1
Lock, Y.W.2
Tanikella, T.K.3
-
34
-
-
0006480470
-
Pharmacological characterization of VPA-985, a potent nonpeptidic orally-active and selective vasopressin (AVP) V2 receptor antagonist
-
Chan PS, Lai F, Ru X, et al. Pharmacological characterization of VPA-985, a potent nonpeptidic orally-active and selective vasopressin (AVP) V2 receptor antagonist. J Am Soc Nephrol 1998;9:A0081
-
(1998)
J Am Soc Nephrol
, vol.9
-
-
Chan, P.S.1
Lai, F.2
Ru, X.3
-
35
-
-
0000639178
-
Pharmacokinetics and pharmacodynamics of a novel vasopressin receptor antagonist, VPA-985, in healthy subjects
-
Muralidharan G, Meng X, DeCleene SA, et al. Pharmacokinetics and pharmacodynamics of a novel vasopressin receptor antagonist, VPA-985, in healthy subjects. Clin Pharmacol Ther 1999;65(2):189
-
(1999)
Clin Pharmacol Ther
, vol.65
, Issue.2
, pp. 189
-
-
Muralidharan, G.1
Meng, X.2
Decleene, S.A.3
-
36
-
-
0036828808
-
Pharmacodynamic effects of a nonpeptide antidiuretic hormone V2 antagonist in cirrhotic patients with ascites
-
DOI 10.1053/jhep.2002.36375
-
Guyader D, Patat A, Ellis-Grosse EJ, et al. Pharmacodynamic effects of a nonpeptide antidiuretic hormone V2 antagonist in cirrhotic patients with ascites. Hepatology 2002;36(5):1197-205 (Pubitemid 35253436)
-
(2002)
Hepatology
, vol.36
, Issue.5 II
, pp. 1197-1205
-
-
Guyader, D.1
Patat, A.2
Ellis-Grosse, E.J.3
Orczyk, G.P.4
-
37
-
-
78650292478
-
Single dose pharmacokinetic (PK)-pharmacodynamic (PD) profile of VPA-985, a novel, V2 receptor antagonist, in patients with congestive heart failure (CHF) [abstract]
-
Ellis-Grosse EJ, Meng X, Orczyk GP. Single dose pharmacokinetic (PK)-pharmacodynamic (PD) profile of VPA-985, a novel, V2 receptor antagonist, in patients with congestive heart failure (CHF) [abstract]. AAPS PharmSci 1999;1:S1
-
(1999)
AAPS PharmSci
, vol.1
-
-
Ellis-Grosse, E.J.1
Meng, X.2
Orczyk, G.P.3
-
38
-
-
78650264875
-
The effect on renal function of lixivaptan (VPA-985), a vasopressin V2 receptor antagonist, in combination with furosemide [abstract 618]
-
Orlandi C, Ticho B. The effect on renal function of lixivaptan (VPA-985), a vasopressin V2 receptor antagonist, in combination with furosemide [abstract 618]. Eur J Heart Fail 2009;8:2
-
(2009)
Eur J Heart Fail
, vol.8
, pp. 2
-
-
Orlandi, C.1
Ticho, B.2
-
39
-
-
4244077065
-
Interaction between VPA-985, an ADH (V2) antagonist, and furosemide
-
Swan SK, Lambrecht LJ, Orczyk GP, et al. Interaction between VPA-985, an ADH (V2) antagonist, and furosemide. J Am Soc Nephrol 1999;10:124A
-
(1999)
J Am Soc Nephrol
, vol.10
-
-
Swan, S.K.1
Lambrecht, L.J.2
Orczyk, G.P.3
-
40
-
-
0000849114
-
VPA-985: A novel non-peptide competitive vasopressin receptor antagonist for the treatment of dilutional hyponatremia
-
abstract A0544
-
Epstein M, Orczyk G, Muralidharan G, et al. VPA-985: A novel non-peptide competitive vasopressin receptor antagonist for the treatment of dilutional hyponatremia. J Am Soc Nephrol 1998;9:abstract A0544
-
(1998)
J Am Soc Nephrol
, vol.9
-
-
Epstein, M.1
Orczyk, G.2
Muralidharan, G.3
-
41
-
-
4244077065
-
Pharmacodynamic effects of VPA-985, an ADH (V2) antagonist, in normal volunteers
-
Swan SK, Anjum S, Lambrecht LJ, et al. Pharmacodynamic effects of VPA-985, an ADH (V2) antagonist, in normal volunteers. J Am Soc Nephrol 1999;10:124A
-
(1999)
J Am Soc Nephrol
, vol.10
-
-
Swan, S.K.1
Anjum, S.2
Lambrecht, L.J.3
-
42
-
-
79955832325
-
Effects of single dose administration of lixivaptan, a selective V2 receptor antagonist, or furosemide in healthy volunteers [abstract 1064]
-
Abraham W, Ghali J, Braman V, et al. Effects of single dose administration of lixivaptan, a selective V2 receptor antagonist, or furosemide in healthy volunteers [abstract 1064]. Eur J Heart Fail 2010;9:1
-
(2010)
Eur J Heart Fail
, vol.9
, pp. 1
-
-
Abraham, W.1
Ghali, J.2
Braman, V.3
-
43
-
-
78650302683
-
Pharmacodynamic (PD) effects of a novel, non-peptide, V2 receptor antagonist, VPA-985 (VPA), given with hydrochlorothiazide (H) [abstract PI-84]
-
Patat A, Ellis Grosse EJ, Orczyk G, et al. Pharmacodynamic (PD) effects of a novel, non-peptide, V2 receptor antagonist, VPA-985 (VPA), given with hydrochlorothiazide (H) [abstract PI-84]. Clin Pharmacol Ther 2000;67:2
-
(2000)
Clin Pharmacol Ther
, vol.67
, pp. 2
-
-
Patat, A.1
Ellis Grosse, E.J.2
Orczyk, G.3
-
44
-
-
78650268190
-
Effect of chronic administration of the vasopressin V2 receptor antagonist lixivaptan (VPA-985) on renal and cardiovascular functions in a rat model of heart failure [abstract 620]
-
Radin J, McCune S, Park S, et al. Effect of chronic administration of the vasopressin V2 receptor antagonist lixivaptan (VPA-985) on renal and cardiovascular functions in a rat model of heart failure [abstract 620]. Eur J Heart Fail 2009;8:2
-
(2009)
Eur J Heart Fail
, vol.8
, pp. 2
-
-
Radin, J.1
McCune, S.2
Park, S.3
-
45
-
-
33646054125
-
Aquaretic effect of lixivaptan, an oral, non-peptide, selective V2 receptor vasopressin antagonist, in New York Heart Association functional class II and III chronic heart failure patients
-
Abraham WT, Shamshirsaz AA, McFann K, et al. Aquaretic effect of lixivaptan, an oral, non-peptide, selective V2 receptor vasopressin antagonist, in New York Heart Association functional class II and III chronic heart failure patients. J Am Coll Cardiol 2006;47:1615-21
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 1615-1621
-
-
Abraham, W.T.1
Shamshirsaz, A.A.2
McFann, K.3
-
46
-
-
0032845180
-
Selective V2-receptor vasopressin antagonism decreases urinary aquaporin-2 excretion in patients with chronic heart failure
-
Martin PY, Abraham WT, Lieming X, et al. Selective V2-receptor vasopressin antagonism decreases urinary aquaporin-2 excretion in patients with chronic heart failure. J Am Soc Nephrol 1999;10(10):2165-70 (Pubitemid 29453494)
-
(1999)
Journal of the American Society of Nephrology
, vol.10
, Issue.10
, pp. 2165-2170
-
-
Martin, P.-Y.1
Abraham, W.T.2
Lieming, X.3
Olson, B.R.4
Oren, R.M.5
Ohara, M.6
Schrier, R.W.7
-
49
-
-
0037223321
-
A vasopressin receptor antagonist (VPA-985) improves serum sodium concentration in patients with hyponatremia: A multicenter, randomized, placebo-controlled trial
-
DOI 10.1053/jhep.2003.50021
-
Wong F, Blei AT, Blendis LM, et al. A vasopressin receptor antagonist (VPA-985) improves serum sodium concentration in patients with hyponatremia: a multicenter, randomized, placebo-controlled trial. Curr Mol Med 2003;37(1):182-91 (Pubitemid 36042159)
-
(2003)
Hepatology
, vol.37
, Issue.1
, pp. 182-191
-
-
Wong, F.1
Blei, A.T.2
Blendis, L.M.3
Thuluvath, P.J.4
-
50
-
-
79955845988
-
The efffects of VPA-985, a vasopressin receptor antagonist on water metabolism in patients with hyponatremia: A multi-center randomized placebo controlled trial [abstract 1094]
-
Wong F, Blei AT, Blendis M, et al. The efffects of VPA-985, a vasopressin receptor antagonist on water metabolism in patients with hyponatremia: a multi-center randomized placebo controlled trial [abstract 1094]. Gastroenterology 2000;118:Suppl 2):4
-
(2000)
Gastroenterology
, vol.118
, Issue.SUPPL. 2
, pp. 4
-
-
Wong, F.1
Blei, A.T.2
Blendis, M.3
-
51
-
-
0344806948
-
Therapy of hyponatremia in cirrhosis with a vasopressin receptor antagonist: A randomized double-blind multicenter trial
-
DOI 10.1053/gast.2003.50143
-
Gerbes AL, Golberg V, Gines P, et al. Therapy of hyponatremia in cirrhosis with a vasopressin receptor antagonist: a randomized double-blind multicenter trial. Gastroenterology 2003;124(4):933-9 (Pubitemid 36389796)
-
(2003)
Gastroenterology
, vol.124
, Issue.4
, pp. 933-939
-
-
Gerbes, A.L.1
Gulberg, V.2
Gines, P.3
Decaux, G.4
Gross, P.5
Gandjini, H.6
Djian, J.7
Azizi, M.8
Bendtsen, F.9
Cales, P.10
Eichler, H.G.11
Gatta, A.12
Gouerou, H.13
Guyader, D.14
Hartmann, A.15
Hensen, J.16
Kantola, I.17
Norbiato, G.18
Vilstrup, H.19
Wikstrom, B.20
more..
-
53
-
-
0000972965
-
VPA-985, an orally active vasopressin receptor antagonist improves hyponatremia in patients with cirrhosis: A double-blind placebo controlled multicenter trial
-
Gerbes AL, Guelberg V, Decaux G, et al. VPA-985, an orally active vasopressin receptor antagonist improves hyponatremia in patients with cirrhosis: a double-blind placebo controlled multicenter trial. Hepatology 1999;30(4 Pt 2):419A
-
(1999)
Hepatology
, vol.30
, Issue.4 PART 2
-
-
Gerbes, A.L.1
Guelberg, V.2
Decaux, G.3
-
54
-
-
4244059288
-
Difference in solute excretion after treatment of hyponatremia related to SIADH or cirrhosis by the non-peptide, oral active selective vasopressin V2 receptor antagonist, VPA-985
-
Decaux G, Hannotier P, Pennickx R, et al. Difference in solute excretion after treatment of hyponatremia related to SIADH or cirrhosis by the non-peptide, oral active selective vasopressin V2 receptor antagonist, VPA-985. J Am Soc Nephrol 1999;10:120A
-
(1999)
J Am Soc Nephrol
, vol.10
-
-
Decaux, G.1
Hannotier, P.2
Pennickx, R.3
-
55
-
-
0034962769
-
2 receptor antagonist VPA-985
-
DOI 10.1067/mlc.2001.116025
-
Decaux G. Difference in solute excretion during correction of hyponatremic patients with cirrhosis or syndrome of inappropriate secretion of antidiuretic hormone by oral vasopressin V2 receptor antagonist VPA-985. J Lab Clin Med 2001;138(1):18-21 (Pubitemid 32589198)
-
(2001)
Journal of Laboratory and Clinical Medicine
, vol.138
, Issue.1
, pp. 18-21
-
-
Decaux, G.1
-
56
-
-
0003308316
-
Correction of hyponatremia by a single oral dose of 75 mg of the non-peptide vasopressin V2 antagonist VPA-985 in hyponatremic patients receiving carbamazepine (CBZ) (Tegretol) or oxcarbazepine (OBZ) (Trileptal)
-
Bichet DG, Remillard G, Madore F, et al. Correction of hyponatremia by a single oral dose of 75 mg of the non-peptide vasopressin V2 antagonist VPA-985 in hyponatremic patients receiving carbamazepine (CBZ) (Tegretol) or oxcarbazepine (OBZ) (Trileptal). J Am Soc Nephrol 1999;10:119A
-
(1999)
J Am Soc Nephrol
, vol.10
-
-
Bichet, D.G.1
Remillard, G.2
Madore, F.3
-
59
-
-
79955830157
-
-
CardioKine Inc Clinicaltrials.gov. NCT01056848
-
CardioKine, Inc. International, multicenter study of a twenty-eight week, open-label, titrated oral lixivaptan administration in patients with chronic hyponatremia: extension to studies CK-LX3401, 3405, and 3430. Clinicaltrials.gov. NCT01056848. Available from: http://clinicaltrials.gov/ ct2/show/NCT01056848
-
International Multicenter Study of A Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients with Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430
-
-
-
61
-
-
0028558373
-
Effects of oral AVP receptor antagonists OPC-21268 and OPC-31260 on congestive heart failure in conscious in dogs
-
Naitoh M, Suzuki H, Murakami M, et al. Effects of oral AVP receptor antagonists OPC-21268 and OPC-31260 on congestive heart failure in conscious in dogs. Am J Physiol 1994;267:H2245-54
-
(1994)
Am J Physiol
, vol.267
-
-
Naitoh, M.1
Suzuki, H.2
Murakami, M.3
-
62
-
-
33947713810
-
Effects of oral tolvaptan in patients hospitalized for worsening heart failure: The EVEREST outcome trial
-
DOI 10.1001/jama.297.12.1319
-
Konstam MA, Gheorghiade M, Burnett JC, et al. Effects of oral tolvaptan in patients hospitalized for worsening heart failure, the EVEREST outcome trial. JAMA 2007;297:1319-31 (Pubitemid 46513233)
-
(2007)
Journal of the American Medical Association
, vol.297
, Issue.12
, pp. 1319-1331
-
-
Konstam, M.A.1
Gheorghiade, M.2
Burnett Jr., J.C.3
Grinfeld, L.4
Maggioni, A.P.5
Swedberg, K.6
Udelson, J.E.7
Zannad, F.8
Cook, T.9
Ouyang, J.10
Zimmer, C.11
Orlandi, C.12
-
63
-
-
33947719178
-
Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: The EVEREST clinical status trials
-
DOI 10.1001/jama.297.12.1332
-
Gheorghiade M, Konstam MA, Burnett JC, et al. Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure, the EVEREST clinical status trials. JAMA 2007;297:1332-43 (Pubitemid 46513234)
-
(2007)
Journal of the American Medical Association
, vol.297
, Issue.12
, pp. 1332-1343
-
-
Gheorghiade, M.1
Konstam, M.A.2
Burnett Jr., J.C.3
Grinfeld, L.4
Maggioni, A.P.5
Swedberg, K.6
Udelson, J.E.7
Zannad, F.8
Cook, T.9
Ouyang, J.10
Zimmer, C.11
Orlandi, C.12
|