Signal enhancement of abiotically-synthesized RNA oligonucleotides and other biopolymers using unmodified fused silica in MALDI-MS

Journal of the American Society for Mass Spectrometry

Volumn 22, Issue 6, 2011, Pages 1100-1104

  Cassidy, Lauren M ^a   Dong, Yingying ^a   Joshi, Prakash C ^a   Aldersley, Michael F ^a   Ferris, James P ^a   McGown, Linda B ^a  

^a Rensselaer Polytechnic Institute   (United States)

Author keywords

Biopolymers; Dextran; DNA; Fused silica target; Heparin; MALDI MS; Prebiotic synthesis; RNA; RNA world

Indexed keywords

ACTIVATED MONOMERS; ANALYTES; ANALYTICAL APPLICATIONS; ANIONIC BIOPOLYMER; BINDING LIGANDS; CLAY SURFACES; DNA OLIGONUCLEOTIDES; HEPARIN; LOW MASS; MALDI TARGETS; MALDI-MS; PREBIOTICS; RAPID SCREENING; RNA WORLD; SIGNAL ENHANCEMENT; SILICA SURFACE;

BIOMOLECULES; BIOPOLYMERS; DESORPTION; DEXTRAN; GLUCOSE; OLIGONUCLEOTIDES; ORGANIC POLYMERS; RNA; SIGNAL DETECTION; STAINLESS STEEL;

FUSED SILICA;

DEXTRAN; DNA OLIGONUCLEOTIDE; HEPARIN; OLIGONUCLEOTIDE; POLYADENYLIC ACID; POLYURIDYLIC ACID; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL ANALYSIS; CHEMICAL MODIFICATION; CONTROLLED STUDY; DNA DETERMINATION; IMAGE ENHANCEMENT; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEOTIDE METABOLISM; PH; RNA ANALYSIS; SIGNAL DETECTION; SURFACE PROPERTY;

ANIONS; BIOLOGICAL PROCESSES; BIOPOLYMERS; DEXTRANS; DNA; IMIDAZOLES; OLIGONUCLEOTIDES; RNA; SILICON DIOXIDE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 79955801048     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-011-0113-0     Document Type: Article

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