MRI-based quantification of Duchenne muscular dystrophy in a canine model

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7965, Issue , 2011, Pages

  Wang, Jiahui ^a   Fan, Zheng ^a   Kornegay, Joe N ^a   Stynera, Martin A ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Biomarker; Canine model; Duchenne muscular dystrophy; Golden retriever muscular dystrophy; MRI

Indexed keywords

CANINE MODELS; DISEASE PROGRESSION; FEATURE ANALYSIS; MEAN INTENSITY; MRI; MRI SCAN; MUSCLE SEGMENTATION; MUSCLE VOLUME; MUSCULAR DYSTROPHY; NATURAL HISTORY; NON-INVASIVE; PERFUSION DATA; PERFUSION STUDIES; PRE-PROCESSING; QUANTITATIVE ANALYSIS; SEMI-AUTOMATED; T2 WEIGHTED; THERAPEUTIC EFFECTS;

BIOMARKERS; GENES; MEDICAL IMAGING; MUSCLE; NEUROMUSCULAR REHABILITATION; RESONANCE;

MAGNETIC RESONANCE IMAGING;

EID: 79955794780     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.878296     Document Type: Conference Paper

References (38)

1. Moser, H., "Duchenne muscular dystrophy: Pathogenetic aspects and genetic prevention, " Human Genetics 66(1), 17-40 (1984). (Pubitemid 14159042)
2. Hoffman, E. P., Brown, R. H., and Kunkel, L. M., "Dystrophin: the protein product of the Duchenne muscular dystrophy locus, " Cell 51(6), 919-928 (1987).
3. Koenig, M., Hoffman, E. P., Bertelson, C. J., Manaco, A. P., Feener, C., and Kunkel, L. M., "Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organizationof the DMD gene in normal and affected individuals, " Cell 50(3), 509-517 (1987). (Pubitemid 18098338)
4. Cheung, J. Y, Bonventre, J. V, Malis, C. D, and Leaf, A., "Calcium and ischemic injury, " N Engl J Med 314(26), 1670-1676 (1986). (Pubitemid 16097844)
5. Edwards, R. H., Newham, D. J., Jones, D. A., and Chapman, S. J., "Role of mechanical damage in pathogenesis of proximal myopathy in man, " The Lancet 323(8376), 548-552 (1984).
6. Brooke, M. H., Fenichel, G. M., Griggs, R. C., Mendell, J. R., Moxley III, R. T., Miller, J. P., Kaiser, K. K., Florence, J. M., Pandya, S., Signore, L., King, W., Robison, J., Head, R. A., Province, M. A., Seyfried, W., and Mandel, S., "Clinical investigation of Duchenne muscular dystrophy. Interesting results in a trial of prednisone, " Arch Neurol 44(8), 812-817 (1987).
7. Fenichel, G. M., Florence, J. M., Pestronk, A., Mendell, J. R., Moxley III, R. T., Miller, J. P., Griggs, R. C., Robison, J., King, W., Signore, L., Pandya, S., Schierbecker, J., and Wilson, B., "Long-term benefit from prednisone therapy in Duchenne muscular dystrophy, " Neurology 41(12), 1874-1877 (1991).
8. Griggs, R. C., Moxley III, R. T., Mendell, J. R., Fenichel, G. M., Brooke, M. H., Pestronk, A., and Miller, J. P., "Prednisone in Duchenne dystrophy. A randomized, controlled trial defining the time course and dose response. Clinical Investigation of Duchenne Dystrophy Group, " Arch Neurol 48(4), 383-388 (1991).
9. Griggs, R. C., Moxley III, R. T., Mendell, J. R., Fenichel, G. M., Brooke, M. H., Pestronk, A., Miller, J. P., Cwik, V. A., Pandya, S., Robison, J., King, W., Signore, L., Schierbecker, J., Florence, J., Matheson-Burden, N., and Wilson, B. "Duchenne dystrophy: randomized, controlled trial of prednisone (18 months) and azathioprine (12 months), " Neurology 43(3), 520-527 (1993). (Pubitemid 23088485)
10. Bulfield, G. Siller, W. G., Wight, P. A. L., and Moore, K. J., "X chromosome-linked muscular dystrophy (mdx) in the mouse, " Proc Natl Acad Sci USA 81(4), 1189-1192 (1984). (Pubitemid 14171480)
11. Gillis, J. M., "Understanding dystrophinopathies: an inventory of the structural and functional consequences of the absence of dystrophin in muscles of the mdx mouse, " J Muscle Res Cell Motil 20(7), 605-625 (1999). (Pubitemid 30068167)
12. Kornegay, J. N., Tuler, S. M., Miller, D. M., and Levesque, D. C., "Muscular dystrophy in a litter of golden retriever dogs, " Muscle Nerve 11(10), 1056-1064 (1988).
13. Cooper, B. J., Winand, W. N., Stedman, H., Valentine, B. A., Hoffman, E. P., Kunkel, L. M., Scott, M., Fischbeck, K. H., Kornegay, J. N., Avery, R. J., Williams, J. R., Schimickel, R. D., and Sylvester, J. E., "The homologue of the Duchenne locus is defective in X-linked muscular dystrophy of dogs, " Nature 334(6178), 154-156 (1988).
14. Jones, B. R., Brennan, S., Mooney, C. T., Callanan, J. J., McAllister, H., Guo, L. T., Martin, P. T., Engvall, E., and Shelton, G. D., "Muscular dystrophy with truncated dystrophin in a family of Japanese Spitz dogs, " J Neurol Sci 217(2), 143-149 (2004). (Pubitemid 38056547)
15. Baltzer, W. I., Calise, D. V., Levine, J. M., Shelton, G. D., Edwards, J. F., and Steiner, J. M. "Dystrophin-deficient muscular dystrophy in a Weimaraner, " J Am Anim Hosp Assoc 43(4), 227-232 (2007). (Pubitemid 47099162)
16. Shelton, G. D., and Engvall, E., "Canine and feline models of human inherited muscle diseases, " Neuromuscular Disord 15(2), 127-138 (2005). (Pubitemid 40202739)
17. Coulton, G. R., Morgan, J. E., Partridge, T. A., and Sloper, J. C., "The mdx mouse skeletal muscle myopathy: I. A histological, morphometric and biochemical investigation, " Neuropathol Appl Neurobiol 14(1), 53-70 (1988).
18. Childers, M. K., Okamura, C. S., Bogan, D. J., Bogan, J. R., Sullivan, M. J., and Kornegay, J. N., "Myofiber injury and regeneration in a canine homologue of Duchenne muscular dystrophy, " Am J Phys Med Rehab 80(3), 175-181 (2001). (Pubitemid 32179980)
19. Kornegay, J. N., Cundiff, D. D., Bogan, D. J., Bogan, J. R., and Okamura, C. S., "The cranial sartorius muscle undergoes true hypertrophy in dogs with golden retriever muscular dystrophy, " Neuromuscul Disord. 13(6), 493- 500 (2003). (Pubitemid 36937126)
20. Liu, J. M. K., Okamura, C. S., Bogan, D. J., Bogan, J. R., Childers, M. K., and Kornegay, J. N., "Effects of prednisone in canine muscular dystrophy, " Muscle Nerve 30(6), 767-773 (2004). (Pubitemid 39601293)
21. Bartlett, R. J., Stockinger, S., Denis, M. M., Bartlett, W. T., Inverardi, L., Le, T. T., thi Man, N., Morris, G. E., Bogan, D. J., Metcalf-Bogan, J., and Kornegay, J. N., "In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA/DNA oligonucleotide, " Nat Biotechnol 18(6), 615-622 (2000). (Pubitemid 30415294)
22. Howell, J. M., Fletcher, S., O'Hara, A., Johnsen, R. D., Lloyd., F., and Kakulas, B. A., "Direct dystrophin and reporter gene transfer into dog muscle in vivo, " Muscle Nerve 21(2), 159-165 (1998). (Pubitemid 28079734)
23. Howell, J.M., Lochmuller, H., O'Hara, A., Fletcher, S., Kakulas, B. A., Massie, B., Nalbantoglu, J., and Karpati, G., "High-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscle of dystrophic dogs: prolongation of expression with immunosuppression, " Hum Gene Ther 9(5), 629-634 (1998). (Pubitemid 28200619)
24. Cerletti, M., Negri, T., Cozzi, F., Colpo, R., Andreetta, F., Croci, D., Davies, K. E., Cornelio, F., Pozza, O., Karpati, G., Gilbert, R., and Mora, M., "Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer, " Gene Ther 10(9), 750-757 (2003). (Pubitemid 36621818)
25. Dell'Agnola C, Wang Z, Storb R, Tapscott, S. J., Kuhr, C. S., Hauschka, S. D., Lee, R. S., Sale, G. E., Zellmer, E., Gisburne, S., Bogan, J., Kornegay, J. N., Cooper, B. J., Gooley, T. A., and Little, M. T., "Hematopoietic stem cell transplantation does not restore dystrophin expression in Duchenne muscular dystrophy dogs, " Blood 104(13), 4311-4318 (2004). (Pubitemid 39620188)
26. Sampaolesi, M., Blot, S., D'Antona, G., Granger, N., Tonlorenzi, R., Innocenzi, A., Mognol, P., Thibaud, J. L., Galvez, B. G., Barthélé my, I., Perani, L., Mantero, S., Guttinger, M., Pansarasa, O., Rinaldi, C., Cusella, D., Angelis, M. G., Torrente, Y., Bordignon, C., Bottinelli, R., and Cossu, G., "Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs, " Nature 444(7119), 574-579 (2006). (Pubitemid 44864430)
27. Prior, T. W., and Bridgeman, S. J., "Experience and strategy for the molecular testing of Duchenne muscular dystrophy, " J Molec Diag 7(3), 317-326 (2005). (Pubitemid 41149646)
28. Marden, F. A., Connolly, A. M., Siegel, M. J., and Rubin, D. A., "Compositional analysis of muscle in boys with Duchenne muscular dystrophy using MR imaging, " Skeletal Radiol 34(3), 140-148 (2005). (Pubitemid 40305454)
29. Lovitt, S., Moore, S. L., and Marden, F. A., "The use of MRI in the evaluation of myopathy, " Clin Neurophysiol 117(3), 486-495 (2006). (Pubitemid 43343981)
30. Wren, T. A., Bluml, S., Tseng-Ong, L., and Gilsanz, V., "Three-point technique of fat quantification of muscle tissue as a marker of disease progression in Duchenne muscular dystrophy: preliminary study, " AJR Am J Roentgenol 190(1), W8-12 (2008).
31. Mavrogeni, S., Papavasiliou, A., Douskou, M., Kolovou, G., Papadopoulou, E., and Cokkinos, D. V., "Effect of deflazacort on cardiac and sternocleidomastoid muscles in Duchenne muscular dystrophy: a magnetic resonance imaging study, " Eur J Paediatr Neurol 13(1), 34-40 (2009).
32. Kim, H. K., Laor, T., Horn, P. S., Racadio, J. M., Wong, B., and Dardzinski, B. J., "T2 mapping in duchenne muscular dystrophy: distribution of disease activity and correlation with clinical assessments, " Radiology 255(3), 899-908 (2010).
33. Mathur, S., Lott, D. J., Senesac, C., Germain, S. A., Vohra, R. S., Sweeney, H. L., Walter, G. A., and Vandenborne, K., "Age-related differences in lower-limb muscle cross-sectional area and torque production in boys with duchenne muscular dystrophy, " Arch Phys Med Rehabil 91(7), 1051-1058 (2010).
34. Thibaud, J. L., Monnet, A., Bertoldi, D., Barthelemy, I., Blot, S., and Carlier, P. G., "Characterization of dystrophic muscle in golden retriever muscular dystrophy dogs by nuclear magnetic resonance imaging, " Neuromuscul Disord 17(7), 575-584 (2007). (Pubitemid 46920965)
35. Yokota, T., Lu, Q. L., Partridge, T., Kobayashi, M., Nakamura, A., Takeda, S., and Hoffman E., "Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs, " Ann Neurol 65(6), 667-676 (2009).
36. Kobayashi, M., Nakamura, A., Hasegawa, D., Fujita, M., Orima, H., and Takeda, S., "Evaluation of dystrophic dog pathology by fat-suppressed T2-weighted imaging, " Muscle Nerve 40(5), 815-826 (2009).
37. Kornegay, J. N., Li, J., Bogan, J. R., Bogan, D. J., Chen, C., Zheng, H., Wang, B., Qiao, C., Howard Jr, J., F., and Xiao, X., "Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs, " Molecular Therapy 18(8), 1501-1508 (2010).
38. Perona, P., and Malik, J., "Scale-space and edge detection using anisotropic diffusion, " IEEE Transactions on Pattern Analysis Machine Intelligence 12(7), 629-639 (1990). (Pubitemid 20726016)