Comparative proteomic approach in differentiating multicentric occurrence and intrahepatic metastasis in multinodular hepatocellular carcinomas

Chinese Journal of Cancer

Volumn 29, Issue 1, 2010, Pages 50-55

  Su, Ming ^a   Li, Le Qun ^a   Peng, Tao ^a   Guo, Ya ^a   Xiao, Kai Yin ^a   Shang, Li Ming ^a   Xu, Bang Hao ^a   Li, Shi Lai ^a   Su, Zhi Xiong ^a   Ye, Xin Ping ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Intrahepatic metastasis; Multicentric occurrence; Multinodular hepatocellular carcinoma; Proteomics

Indexed keywords

PROTEIN DERIVATIVE;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPARATIVE PROTEOMIC; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; LIVER METASTASIS; MALE; MULTIPLE CANCER; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PROTEOMICS; TISSUE SECTION; COMPARATIVE STUDY; LIVER TUMOR; MASS SPECTROMETRY; METABOLISM; METASTASIS; MIDDLE AGED; PATHOLOGY; PROTEIN MICROARRAY; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ADULT; CARCINOMA, HEPATOCELLULAR; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASMS, MULTIPLE PRIMARY; PROTEIN ARRAY ANALYSIS; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 79955790835     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.009.10336     Document Type: Article

References (22)

1. Okuda K, Peters PL, Si mson IW. Gross anatomic features of hepatocellular carcinoma from three disparate geographic areas: proposal of new classification [J]. Cancer, 1984, 54(10):2165-2173.
2. Yamamoto T, Kajino K, Kudo M, et al. Determination of the clonal origin of multiple human hepatocellular carcinomas by cloning and polymerase chain reaction of the integrated of hepatitis B virus DNA [J]. Hepatology, 1999, 29(5):1446-1452.
3. Nowell PC. The clonal evolution of tumor cell populations [J]. Science, 1976, 194(4260):23-28.
4. Calabrese P, Tavare S, Shibata D. Pretumor progression: clonal evolution of human stem cell populations [J]. Am J Pathol, 2004, 164(4):1337-1346.
5. Yasui M, Harada A, Nonami T, et al. Potentially multicentric hepatocellular carcinoma:clinicopathologic characteristics and postoperative prognosis [J]. World J Surg, 1997, 21(8):860-865.
6. Li LQ, Peng T, Lin JL, et al. Clonal origin of recurrent hepatocellular carcinoma and its relationship with time of recurrence [J]. Chin J Hepatobiliary Surg, 1999, 5(1):11-13. [in Chinese]
7. Pontisso P, Belluco C, Bertorelle R, et al. Hepatitis C virus infection associated with human hepatocellular carcinoma: lack of correlation with p53 abnormalities in Caucasian patients [J]. Cancer, 1998, 83 (8):1489-1494.
8. Takashima M, Kuramitsu Y, Yokoyama Y, et al. Overexpression of alpha enolase in hepatitis C virus-related hepatocellular carcinoma: association with tumor progression as determined by proteomic analysis [J]. Proteomics, 2005, 5(6):1686-1692.
9. Li C, Tan YX, Zhou H, et al. Proteomic analysis of hepatitis B virus-associated hepatocellular carcinoma: Identification of potential tumor markers [J]. Proteomics, 2005, 5(4):1125-1139.
10. Yokoyamal Y, Kuramitsu Y, Takashima M, et al. Proteomic profiling of proteins decreased in hepatocellular carcinoma from patients infected with hepatitis C virus [J]. Proteomics, 2004, 4(7):2111-2116.
11. Simonnet H, Alazard N, Pfeiffer K, et al. Low mitochondrial respiratory chain content correlated with tumor aggressiveness in renal cell carcinoma [J]. Carcinogenesis, 2002, 23(5):759-768.
12. Barazi HO, Zhou L, Templeton NS, et al. Identification of heat shock protein 60 as a molecular mediator of alpha 3 beta 1 integrin activation [J]. Cancer Res, 2002, 62(5):1541-1548.
13. Kuramitsu Y, Nakamura K. Current progress in proteomic study of hepatitis C virus-related human hepatocellular carcinoma [J]. Expert Rev Proteomics, 2005, 2(4):589-601.
14. Luk JM, Lam CT, Siu AF, et al. Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values [J]. Proteomics, 2006, 6(3):1049-1057.
15. Lim SO, Park SG, Yoo JH, et al. Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular carcinomas and dysplastic nodules [J]. World J Gastroenterol, 2005, 11(14): 2072-2079.
16. Su RJ, Li Z, Cheng LF, et al. The effects of specific down-regulation of Grp78 by siRNA on invasion and metastasis of hepatocellular carcinoma [J]. Chin J Cell Biol, 2007, 29(6):889-894. [in Chinese]
17. Teramoto R, Minagawa H, Honda M, et al. Protein expression profile characteristic to hepatocellular carcinoma revealed by 2D-DIGE with supervised learning [J]. Biochem Biophys Acta, 2008, 1784(5):764-772.
18. Fraga CH, True LD, Kirk D. Enhanced expression of the mesenchymal marker, vimentin, in hyperplastic versus normal human prostatic epithelium [J]. J Urol, 1998, 159(1):270-274.
19. Hu L, Lau SH, Tzang CH, et al. Association of Vimentin overexpression and hepatocellular carcinoma metastasis [J]. Oncogene, 2004, 23(1):298-302.
20. Ye LH, Qin XR, Zhang XD, et al. Proteomics analysis of differentially expressed tropomyosin, vimentin and HSP70 in highly metastatic subline of human hepatoma cells [J]. Chin J Biochem Mol Biol, 2005, 21(2):244-249. [in Chinese]
21. Pawlak G, McGarvey TW, Ngnyen TB. Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder [J]. Int J Cancer, 2004, 110(3):368-373.
22. Sibley K, Cuthbert-Heavens D, Knowles MA. Loss of heterozy-gosityat 4pl6.3 and mutation of FGFR-3 in transitional cell carcinoma [J]. Oncogene, 2001, 20(6):686-691.