A synthetic haemoglobin-based oxygen carrier and the reversal of cardiac hypoxia secondary to severe anaemia following trauma

Medical Journal of Australia

Volumn 194, Issue 9, 2011, Pages 471-473

  Fitzgerald, Mark C ^a   Chan, Julie Y ^a   Ross, Andrew W ^a   Liew, Susan M ^b   Butt, Warwick W ^a   Baguley, David ^a   Salem, Hatem H ^b   Russ, Matthias K ^b   Deasy, Conor ^c   Martin, Katherine E ^a   Mathew, Joseph K ^a   Rosenfeld, Jeffrey V ^c  

^a Alfred Trauma Service   (Australia)

^b Monash University ^*  (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ASCORBIC ACID; CREATININE; CYANOCOBALAMIN; FIBRINOGEN; FOLIC ACID; GLYCERYL TRINITRATE; HEMOGLOBIN; HEMOGLOBIN BASED OXYGEN CARRIER 201; HEPARIN; IRON; LACTIC ACID; NORADRENALIN; PROGESTERONE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; RECOMBINANT ERYTHROPOIETIN; RINGER LACTATE SOLUTION; TROPONIN I; UNCLASSIFIED DRUG; VITAMIN K GROUP;

ADULT; ANEMIA; APPLICATION SITE INFECTION; ARTICLE; BLEEDING; BLOOD PRESSURE; BREATHING RATE; CASE REPORT; COGNITION; COMPUTER ASSISTED TOMOGRAPHY; CREATININE BLOOD LEVEL; ECHOGRAPHY; EMERGENCY CARE; ENZYME BLOOD LEVEL; EPIDURAL HEMATOMA; EVOKED SOMATOSENSORY RESPONSE; FEMALE; FEMORAL PIN SITE INFECTION; FEMUR FRACTURE; FEVER; FIBRINOGEN BLOOD LEVEL; FRACTURE; FRACTURE DISLOCATION; FRACTURE EXTERNAL FIXATION; GLASGOW COMA SCALE; HEART MUSCLE ISCHEMIA; HEART OUTPUT; HEART RATE; HEART RIGHT VENTRICLE; HEART RIGHT VENTRICLE FUNCTION; HEART RIGHT VENTRICLE WALL MOTION ABNORMALITY; HEART VENTRICLE TACHYCARDIA; HEART VENTRICLE WALL MOTION; HEMATOPOIESIS; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMERUS FRACTURE; INFERIOR CAVA VEIN; INJURY SEVERITY; INTERNATIONAL NORMALIZED RATIO; JEHOVAH'S WITNESS; LACTATE BLOOD LEVEL; LOW DRUG DOSE; MENSTRUATION; MULTIPLE TRAUMA; OSTEOSYNTHESIS; OXYGEN SATURATION; PARTIAL THROMBOPLASTIN TIME; PERICARDIAL EFFUSION; PERITONEAL FLUID; PLEURA EFFUSION; PNEUMONIA; PNEUMOTHORAX; PULSE OXIMETRY; PUPIL REFLEX; SEDATION; SINUS TACHYCARDIA; ST SEGMENT; ST SEGMENT DEPRESSION; THORACOLUMBAR SPINE; THORACOTOMY; TRAFFIC ACCIDENT; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; TREATMENT OUTCOME; URINE VOLUME; VENA CAVA FILTER;

EID: 79955784559     PISSN: 0025729X     EISSN: 13265377     Source Type: Journal    
DOI: 10.5694/j.1326-5377.2011.tb03064.x     Document Type: Article

References (13)

1. Katz LM, Manning JE, McCurdy S, et al. Nitroglycerin attenuates vasoconstriction of HBOC-201 during hemorrhagic shock resuscitation. Resuscitation 2010; 81: 481-487.
2. Evans JA, van Wessem KJ, McDougall D, et al. Epidemiology of traumatic deaths: comprehensive population-based assessment. World J Surg 2010; 34: 158-163.
3. Atkin C, Freedman I, Rosenfeld JV, et al. The evolution of an integrated State Trauma System in Victoria, Australia. Injury 2005; 36: 1277-1287.
4. Weiskopf RB, Viele MK, Feiner J, et al. Human cardiovascular and metabolic response to acute, severe isovolemic anemia. JAMA 1998; 279: 217-221.
5. Weiskopf RB. Emergency transfusion for acute severe anemia: a calculated risk. Anesth Analg 2010; 111: 1088-1092.
6. Corporation B. Hemopure. Cambridge, Mass: Biopure Corporation, 2008. http://www.hemopure.co.za/downloads/HemopureSouthAfrica_ PI.pdf (accessed Mar 2011).
7. Marinaro J, Smith J, Tawil I, et al. HBOC-201 use in traumatic brain injury: case report and review of literature. Transfusion 2009; 49: 2054-2059.
8. Mackenzie CF, Morrison C, Jaberi M, et al. Management of hemorrhagic shock when blood is not an option. J Clin Anesth 2008; 20: 538-541.
9. Sarani B, Pryor J. Hemoglobin-based oxygen carriers as rescue therapy: justified experiment or unnecessary risk [editorial]? J Clin Anesth 2008; 20: 489-491.
10. Natanson C, Kern SJ, Lurie P, et al. Cell-free hemoglobin-based blood substitutes and risk of myocardial infarction and death: a meta-analysis. JAMA 2008; 299: 2304-2312.
11. Mackenzie CF, Moon-Massat PF, Shander A, et al. When blood is not an option: factors affecting survival after the use of a hemoglobin-based oxygen carrier in 54 patients with life-threatening anemia. Anesth Analg 2010; 110: 685-693.
12. Mackenzie CF. Haemoglobin-based oxygen carriers: is the benefit worth the risk? Br J Hosp Med (Lond) 2009; 70: 26-30.
13. Donahue LL, Shapira I, Shander A, et al. Management of acute anemia in a Jehovah's Witness patient with acute lymphoblastic leukemia with polymerized bovine hemoglobin-based oxygen carrier: a case report and review of literature. Transfusion 2010; 50: 1561-1567.