Physico-chemical Effects of the major quassinoids in a standardized Eurycoma longifolia extract (Fr 2) on the bioavailability and pharmacokinetic properties, and their implications for oral antimalarial activity

Natural Product Communications

Volumn 6, Issue 3, 2011, Pages 337-341

  Low, Bin Seng ^a   Teh, Chin Hoe ^a   Yuen, Kah Hay ^a   Chan, Kit Lam ^a  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

Author keywords

Anti malarial activity; Bioavailability; Eurycoma longifolia; Pharmacokinetics; Physico chemical factors; Quassinoids; Standardized extract FR 2

Indexed keywords

13ALPHA(21) EPOXYEURYCOMANONE; 13ALPHA, 21 DIHYDROEURYCOMANONE; EURYCOMA LONGIFOLIA EXTRACT; EURYCOMANOL; EURYCOMANONE; OCTANOL; QUASSINOID DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ACIDITY; ANIMAL EXPERIMENT; ANTIMALARIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DEGRADATION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; EURYCOMA; EURYCOMA LONGIFOLIA; HYDROPHILICITY; LIPOPHILICITY; MALE; MAXIMUM PLASMA CONCENTRATION; MEMBRANE PERMEABILITY; NONHUMAN; PHARMACOKINETICS; PHYSICAL CHEMISTRY; RAT; STOMACH PH;

EURYCOMA LONGIFOLIA; RATTUS;

EID: 79955784387     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1100600307     Document Type: Article

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