메뉴 건너뛰기




Volumn 69, Issue 11, 2011, Pages 1091-1099

Neuropeptide y opposes alcohol effects on gamma-aminobutyric acid release in amygdala and blocks the transition to alcohol dependence

Author keywords

BIBP3226; BIIE0246; central amygdala; negative reinforcement; Y1 receptor; Y2 receptor

Indexed keywords

4 AMINOBUTYRIC ACID; ALCOHOL; NEUROPEPTIDE Y; NEUROPEPTIDE Y2 RECEPTOR;

EID: 79955768156     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.02.004     Document Type: Article
Times cited : (106)

References (44)
  • 1
    • 0004235298 scopus 로고    scopus 로고
    • American Psychiatric Association American Psychiatric Press Washington, DC
    • American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders 1998 American Psychiatric Press Washington, DC
    • (1998) Diagnostic and Statistical Manual of Mental Disorders
  • 2
    • 79955763804 scopus 로고    scopus 로고
    • National Institute on Alcohol Abuse and Alcoholism National Institute on Alcohol Abuse and Alcoholism Washington, DC
    • National Institute on Alcohol Abuse and Alcoholism Five-Year Strategic Plan FY08-13 2007 National Institute on Alcohol Abuse and Alcoholism Washington, DC
    • (2007) Five-Year Strategic Plan FY08-13
  • 4
    • 0026345518 scopus 로고
    • Piecing together the puzzle of basal forebrain anatomy
    • L. Heimer, and G.F. Alheid Piecing together the puzzle of basal forebrain anatomy Adv Exp Med Biol 295 1991 1 42
    • (1991) Adv Exp Med Biol , vol.295 , pp. 1-42
    • Heimer, L.1    Alheid, G.F.2
  • 5
    • 0011918368 scopus 로고
    • Molecular structure of mammalian neuropeptide Y: Analysis by molecular cloning and computer-aided comparison with crystal structure of avian homologue
    • DOI 10.1073/pnas.84.8.2532
    • J. Allen, J. Novotny, J. Martin, and G. Heinrich Molecular structure of mammalian neuropeptide Y: Analysis by molecular cloning and computer-aided comparison with crystal structure of avian homologue Proc Natl Acad Sci U S A 84 1987 2532 2536 (Pubitemid 17075900)
    • (1987) Proceedings of the National Academy of Sciences of the United States of America , vol.84 , Issue.8 , pp. 2532-2536
    • Allen, J.1    Novotny, J.2    Martin, J.3    Heinrich, G.4
  • 6
    • 0024580891 scopus 로고
    • Coexistence of GABA and peptide immunoreactivity in non-pyramidal neurons of the basolateral amygdala
    • DOI 10.1016/0304-3940(89)90659-9
    • A.J. McDonald, and J.C. Pearson Coexistence of GABA and peptide immunoreactivity in non-pyramidal neurons of the basolateral amygdala Neurosci Lett 100 1989 53 58 (Pubitemid 19128149)
    • (1989) Neuroscience Letters , vol.100 , Issue.1-3 , pp. 53-58
    • McDonald, A.J.1    Pearson, J.C.2
  • 7
    • 0024310089 scopus 로고
    • Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models
    • M. Heilig, B. Sderpalm, J.A. Engel, and E. Widerlv Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models Psychopharmacology (Berl) 98 1989 524 529 (Pubitemid 19193902)
    • (1989) Psychopharmacology , vol.98 , Issue.4 , pp. 524-529
    • Heilig, M.1    Soderpalm, B.2    Engel, J.A.3    Widerlov, E.4
  • 8
    • 0027265205 scopus 로고
    • Anxiolytic-like action of neuropeptide Y: Mediation by Y1 receptors in amygdala, and dissociation from food intake effects
    • M. Heilig, S. McLeod, M. Brot, S.C. Heinrichs, F. Menzaghi, G.F. Koob, and K.T. Britton Anxiolytic-like action of neuropeptide Y: Mediation by Y1 receptors in amygdala, and dissociation from food intake effects Neuropsychopharmacology 8 1993 357 363 (Pubitemid 23162961)
    • (1993) Neuropsychopharmacology , vol.8 , Issue.4 , pp. 357-363
    • Heilig, M.1    McLeod, S.2    Brot, M.3    Heinrichs, S.C.4    Menzaghi, F.5    Koob, G.F.6    Britton, K.T.7
  • 9
    • 0036913981 scopus 로고    scopus 로고
    • Neuropeptide Y receptor subtypes in the basolateral nucleus of the amygdala modulate anxiogenic responses in rats
    • DOI 10.1016/S0028-3908(02)00234-4
    • T.J. Sajdyk, D.A. Schober, and D.R. Gehlert Neuropeptide Y receptor subtypes in the basolateral nucleus of the amygdala modulate anxiogenic responses in rats Neuropharmacology 43 2002 1165 1172 (Pubitemid 36009370)
    • (2002) Neuropharmacology , vol.43 , Issue.7 , pp. 1165-1172
    • Sajdyk, T.J.1    Schober, D.A.2    Gehlert, D.R.3
  • 10
    • 0037648675 scopus 로고    scopus 로고
    • Neuropeptide Y reduces oral ethanol intake in alcohol-preferring (P) rats following a period of imposed ethanol abstinence
    • DOI 10.1097/01.ALC.0000065723.93234.1D
    • N.W. Gilpin, R.B. Stewart, J.M. Murphy, T.-K. Li, and N.E. Badia-Elder Neuropeptide Y reduces oral ethanol intake in alcohol-preferring (P) rats following a period of imposed ethanol abstinence Alcohol Clin Exp Res 27 2003 787 794 (Pubitemid 36583361)
    • (2003) Alcoholism: Clinical and Experimental Research , vol.27 , Issue.5 , pp. 787-794
    • Gilpin, N.W.1    Stewart, R.B.2    Murphy, J.M.3    Li, T.-K.4    Badia-Elder, N.E.5
  • 11
    • 44649182704 scopus 로고    scopus 로고
    • Neuropeptide y in the central nucleus of the amygdala suppresses dependence-induced increases in alcohol drinking
    • N.W. Gilpin, K. Misra, and G.F. Koob Neuropeptide Y in the central nucleus of the amygdala suppresses dependence-induced increases in alcohol drinking Pharmacol Biochem Behav 90 2008 475 480
    • (2008) Pharmacol Biochem Behav , vol.90 , pp. 475-480
    • Gilpin, N.W.1    Misra, K.2    Koob, G.F.3
  • 12
    • 53049107757 scopus 로고    scopus 로고
    • Neuropeptide y suppresses ethanol drinking in ethanol-abstinent, but not non-ethanol-abstinent, Wistar rats
    • N.W. Gilpin, R.B. Stewart, and N.E. Badia-Elder Neuropeptide Y suppresses ethanol drinking in ethanol-abstinent, but not non-ethanol-abstinent, Wistar rats Alcohol 42 2008 541 551
    • (2008) Alcohol , vol.42 , pp. 541-551
    • Gilpin, N.W.1    Stewart, R.B.2    Badia-Elder, N.E.3
  • 13
    • 33645979010 scopus 로고    scopus 로고
    • Overexpression of neuropeptide y in the central nucleus of the amygdala decreases ethanol self-administration in "anxious" rats
    • S.D. Primeaux, S.P. Wilson, G.A. Bray, D.A. York, and M.A. Wilson Overexpression of neuropeptide Y in the central nucleus of the amygdala decreases ethanol self-administration in "anxious" rats Alcohol Clin Exp Res 30 2006 791 801
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 791-801
    • Primeaux, S.D.1    Wilson, S.P.2    Bray, G.A.3    York, D.A.4    Wilson, M.A.5
  • 14
    • 34249685489 scopus 로고    scopus 로고
    • Viral vector-induced amygdala NPY overexpression reverses increased alcohol intake caused by repeated deprivations in Wistar rats
    • DOI 10.1093/brain/awm033
    • A. Thorsell, V. Repunte-Canonigo, L.E. O'Dell, S.A. Chen, A.R. King, and D. Lekic Viral vector-induced amygdala NPY overexpression reverses increased alcohol intake caused by repeated deprivations in Wistar rats Brain 130 2007 1330 1337 (Pubitemid 47355946)
    • (2007) Brain , vol.130 , Issue.5 , pp. 1330-1337
    • Thorsell, A.1    Repunte-Canonigo, V.2    O'Dell, L.E.3    Chen, S.A.4    King, A.R.5    Lekic, D.6    Koob, G.F.7    Paolo Sanna, P.8
  • 16
    • 8544225739 scopus 로고    scopus 로고
    • Increased GABA release in the central amygdala of ethanol-dependent rats
    • DOI 10.1523/JNEUROSCI.3004-04.2004
    • M. Roberto, S.G. Madamba, D.G. Stouffer, L.H. Parsons, and G.R. Siggins Increased GABA release in the central amygdala of ethanol-dependent rats J Neurosci 24 2004 10159 10166 (Pubitemid 39492041)
    • (2004) Journal of Neuroscience , vol.24 , Issue.45 , pp. 10159-10166
    • Roberto, M.1    Madamba, S.G.2    Stouffer, D.G.3    Parsons, L.H.4    Siggins, G.R.5
  • 17
    • 77950369440 scopus 로고    scopus 로고
    • Corticotropin releasing factor-induced amygdala gamma-aminobutyric acid release plays a key role in alcohol dependence
    • M. Roberto, M.T. Cruz, N.W. Gilpin, V. Sabino, P. Schweitzer, and M. Bajo Corticotropin releasing factor-induced amygdala gamma-aminobutyric acid release plays a key role in alcohol dependence Biol Psychiatry 67 2010 831 839
    • (2010) Biol Psychiatry , vol.67 , pp. 831-839
    • Roberto, M.1    Cruz, M.T.2    Gilpin, N.W.3    Sabino, V.4    Schweitzer, P.5    Bajo, M.6
  • 18
    • 33745469892 scopus 로고    scopus 로고
    • Nociceptin/orphanin FQ presynaptically decreases GABAergic transmission and blocks the ethanol-induced increase of GABA release in central amygdala
    • DOI 10.1073/pnas.0601899103
    • M. Roberto, and G.R. Siggins Nociceptin/orphanin FQ presynaptically decreases GABAergic transmission and blocks the ethanol-induced increase of GABA release in central amygdala Proc Natl Acad Sci U S A 103 2006 9715 9720 (Pubitemid 43955890)
    • (2006) Proceedings of the National Academy of Sciences of the United States of America , vol.103 , Issue.25 , pp. 9715-9720
    • Roberto, M.1    Siggins, G.R.2
  • 20
    • 0014192718 scopus 로고
    • Polydipsia elicited by the synergistic action of a saccharin and glucose solution
    • E.S. Valenstein, V.C. Cox, and J.W. Kakolewski Polydipsia elicited by the synergistic action of a saccharin and glucose solution Science 157 1967 552 554
    • (1967) Science , vol.157 , pp. 552-554
    • Valenstein, E.S.1    Cox, V.C.2    Kakolewski, J.W.3
  • 22
    • 0030668953 scopus 로고    scopus 로고
    • Autoreceptor-induced inhibition of neuropeptide y release from PC-12 cells is mediated by Y2 receptors
    • X. Chen, D.A. DiMaggio, S.P. Han, and T.C. Westfall Autoreceptor-induced inhibition of neuropeptide Y release from PC-12 cells is mediated by Y2 receptors J Am Physiol 273 1997 H1737 H1744
    • (1997) J Am Physiol , vol.273
    • Chen, X.1    Dimaggio, D.A.2    Han, S.P.3    Westfall, T.C.4
  • 23
    • 27144529605 scopus 로고    scopus 로고
    • 5 receptors
    • DOI 10.1159/000085897
    • F.M. Dautzenberg, and S. Neysari Irreversible binding kinetics of neuropeptide Y ligands to Y2 but not to Y1 and Y5 receptors Pharmacology 75 2005 21 29 (Pubitemid 41491320)
    • (2005) Pharmacology , vol.75 , Issue.1 , pp. 21-29
    • Dautzenberg, F.M.1    Neysari, S.2
  • 24
    • 10044267876 scopus 로고    scopus 로고
    • Allostasis and dysregulation of corticotropin-releasing factor and neuropeptide Y systems: Implications for the development of alcoholism
    • DOI 10.1016/j.pbb.2004.09.020, PII S0091305704003181
    • G.R. Valdez, and G.F. Koob Allostasis and dysregulation of corticotropin-releasing factor and neuropeptide Y systems: Implications for the development of alcoholism Pharmacol Biochem Behav 79 2004 671 689 (Pubitemid 39600607)
    • (2004) Pharmacology Biochemistry and Behavior , vol.79 , Issue.4 , pp. 671-689
    • Valdez, G.R.1    Koob, G.F.2
  • 25
    • 33749532648 scopus 로고    scopus 로고
    • Neuropeptide Y and corticotropin-releasing factor bi-directionally modulate inhibitory synaptic transmission in the bed nucleus of the stria terminalis
    • DOI 10.1016/j.neuropharm.2006.06.011, PII S0028390806001961
    • T.L. Kash, and D.G. Winder Neuropeptide Y and corticotropin-releasing factor bi-directionally modulate inhibitory synaptic transmission in the bed nucleus of the stria terminalis Neuropharmacology 51 2006 1013 1022 (Pubitemid 44528607)
    • (2006) Neuropharmacology , vol.51 , Issue.5 , pp. 1013-1022
    • Kash, T.L.1    Winder, D.G.2
  • 26
    • 0028104939 scopus 로고
    • 2 receptors in rat hippocampal slices in vitro
    • S. Greber, C. Schwarzer, and G. Sperk Neuropeptide Y inhibits potassium-stimulated glutamate release through Y2 receptors in rat hippocampal slices in vitro Br J Pharmacol 113 1994 737 740 (Pubitemid 24326809)
    • (1994) British Journal of Pharmacology , vol.113 , Issue.3 , pp. 737-740
    • Greber, S.1    Schwarzer, C.2    Sperk, G.3
  • 27
    • 0346908976 scopus 로고    scopus 로고
    • Intra-Amygdala Infusion of the NPY Y1 Receptor Antagonist BIBP 3226 Attenuates Operant Ethanol Self-Administration
    • DOI 10.1097/01.ALC.0000098875.95923.69
    • J.P. Schroeder, F. Olive, H. Koenig, and C.W. Hodge Intra-amygdala infusion of the NPY Y1 receptor antagonist BIBP 3226 attenuates operant ethanol self-administration Alcohol Clin Exp Res 27 2003 1884 1891 (Pubitemid 38005056)
    • (2003) Alcoholism: Clinical and Experimental Research , vol.27 , Issue.12 , pp. 1884-1891
    • Schroeder, J.P.1    Olive, F.2    Koenig, H.3    Hodge, C.W.4
  • 28
    • 0037174775 scopus 로고    scopus 로고
    • Blockade of central neuropeptide y (NPY) Y2 receptors reduces ethanol self-administration in rats
    • A. Thorsell, R. Rimondini, and M. Heilig Blockade of central neuropeptide Y (NPY) Y2 receptors reduces ethanol self-administration in rats Neurosci Lett 332 2002 1 4
    • (2002) Neurosci Lett , vol.332 , pp. 1-4
    • Thorsell, A.1    Rimondini, R.2    Heilig, M.3
  • 29
    • 12744256723 scopus 로고    scopus 로고
    • Suppression of ethanol self-administration by the neuropeptide y (NPY) Y2 receptor antagonist BIIE0246: Evidence for sensitization in rats with a history of dependence
    • R. Rimondini, A. Thorsell, and M. Heilig Suppression of ethanol self-administration by the neuropeptide Y (NPY) Y2 receptor antagonist BIIE0246: Evidence for sensitization in rats with a history of dependence Neurosci Lett 375 2005 129 133
    • (2005) Neurosci Lett , vol.375 , pp. 129-133
    • Rimondini, R.1    Thorsell, A.2    Heilig, M.3
  • 30
    • 2942537938 scopus 로고    scopus 로고
    • 2 receptor knockout mice
    • DOI 10.1016/j.peptides.2004.03.009, PII S0196978104001378
    • T.E. Thiele, P. Naveilhan, and P. Ernfors Assessment of ethanol consumption and water drinking by NPY Y(2) receptor knockout mice Peptides 25 2004 975 983 (Pubitemid 38760285)
    • (2004) Peptides , vol.25 , Issue.6 , pp. 975-983
    • Thiele, T.E.1    Naveilhan, P.2    Ernfors, P.3
  • 31
    • 57249114520 scopus 로고    scopus 로고
    • Neuropeptide y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence
    • L. Wetherill, M.A. Schuckit, V. Hesselbrock, X. Xuei, T. Liang, and D.M. Dick Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence Alcohol Clin Exp Res 32 2008 2031 2040
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 2031-2040
    • Wetherill, L.1    Schuckit, M.A.2    Hesselbrock, V.3    Xuei, X.4    Liang, T.5    Dick, D.M.6
  • 32
    • 77951825354 scopus 로고    scopus 로고
    • 203140. 32. The central basolateral amygdala are critical sites of neuropeptide Y/Y2 receptor-mediated regulation of anxiety and depression
    • R.O. Tasan, N.K. Nguyen, S. Weger, S.B. Sartori, N. Singewald, and R. Heilbronn 203140. 32. The central basolateral amygdala are critical sites of neuropeptide Y/Y2 receptor-mediated regulation of anxiety and depression J Neurosci 30 2010 6282 6290
    • (2010) J Neurosci , vol.30 , pp. 6282-6290
    • Tasan, R.O.1    Nguyen, N.K.2    Weger, S.3    Sartori, S.B.4    Singewald, N.5    Heilbronn, R.6
  • 33
    • 26444506279 scopus 로고    scopus 로고
    • Deficits in amygdaloid cAMP-responsive element-binding protein signaling play a role in genetic predisposition to anxiety and alcoholism
    • DOI 10.1172/JCI24381
    • S.C. Pandey, H. Zhang, A. Roy, and T. Xu Deficits in amygdaloid cAMP-responsive element-binding protein signaling play a role in genetic predisposition to anxiety and alcoholism J Clin Invest 115 2005 2762 2773 (Pubitemid 41434403)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2762-2773
    • Pandey, S.C.1    Zhang, H.2    Roy, A.3    Xu, T.4
  • 34
    • 0347360140 scopus 로고    scopus 로고
    • Effects of PKA modulation on the expression of neuropeptide Y in rat amygdaloid structures during ethanol withdrawal
    • DOI 10.1016/j.peptides.2003.08.008
    • H. Zhang, and S.C. Pandey Effects of PKA modulation on the expression of neuropeptide Y in rat amygdaloid structures during ethanol withdrawal Peptides 24 2003 1397 1402 (Pubitemid 38045547)
    • (2003) Peptides , vol.24 , Issue.9 , pp. 1397-1402
    • Zhang, H.1    Pandey, S.C.2
  • 35
    • 0035998897 scopus 로고    scopus 로고
    • The decreased cellular expression of neuropeptide Y protein in rat brain structures during ethanol withdrawal after chronic ethanol exposure
    • DOI 10.1097/00000374-200206000-00008
    • A. Roy, and S.C. Pandey The decreased cellular expression of neuropeptide Y protein in rat brain structures during ethanol withdrawal after chronic ethanol exposure Alcohol Clin Exp Res 26 2002 796 803 (Pubitemid 34666138)
    • (2002) Alcoholism: Clinical and Experimental Research , vol.26 , Issue.6 , pp. 796-803
    • Roy, A.1    Pandey, S.C.2
  • 36
    • 43649105135 scopus 로고    scopus 로고
    • Brain chromatin remodeling: A novel mechanism of alcoholism
    • S.C. Pandey, R. Ugale, H. Zhang, L. Tang, and A. Prakash Brain chromatin remodeling: A novel mechanism of alcoholism J Neurosci 28 2008 3729 3737
    • (2008) J Neurosci , vol.28 , pp. 3729-3737
    • Pandey, S.C.1    Ugale, R.2    Zhang, H.3    Tang, L.4    Prakash, A.5
  • 38
    • 16844374405 scopus 로고    scopus 로고
    • Conceptual framework for the etiology of alcoholism: A 'kindling' /stress hypothesis
    • DOI 10.1007/s00213-004-2016-2
    • G.R. Breese, D.H. Overstreet, and D.J. Knapp Conceptual framework for the etiology of alcoholism: A "kindling"/stress hypothesis Psychopharmacology (Berl) 178 2005 367 380 (Pubitemid 40486977)
    • (2005) Psychopharmacology , vol.178 , Issue.4 , pp. 367-380
    • Breese, G.R.1    Overstreet, D.H.2    Knapp, D.J.3
  • 39
    • 38549123307 scopus 로고    scopus 로고
    • Neuropeptide Y in the amygdala induces long-term resilience to stress-induced reductions in social responses but not hypothalamic-adrenal- pituitary axis activity or hyperthermia
    • DOI 10.1523/JNEUROSCI.0659-07.2008
    • T.J. Sajdyk, P.L. Johnson, R.J. Leitermann, S.D. Fitz, A. Dietrich, and M. Morin Neuropeptide Y in the amygdala induces long-term resilience to stress-induced reductions in social responses but not hypothalamicadrenalpituitary axis activity or hyperthermia J Neurosci 28 2008 893 903 (Pubitemid 351159007)
    • (2008) Journal of Neuroscience , vol.28 , Issue.4 , pp. 893-903
    • Sajdyk, T.J.1    Johnson, P.L.2    Leitermann, R.J.3    Fitz, S.D.4    Dietrich, A.5    Morin, M.6    Gehlert, D.R.7    Urban, J.H.8    Shekhar, A.9
  • 40
    • 33744999429 scopus 로고    scopus 로고
    • The role of neuropeptide Y in the amygdala on corticotropin-releasing factor receptor-mediated behavioral stress responses in the rat
    • DOI 10.1080/10253890600557315, PII L17X103845588
    • T.J. Sajdyk, S.D. Fitz, and A. Shekhar The role of neuropeptide Y in the amygdala on corticotropin-releasing factor receptor-mediated behavioral stress responses in the rat Stress 9 2006 21 28 (Pubitemid 43861157)
    • (2006) Stress , vol.9 , Issue.1 , pp. 21-28
    • Sajdyk, T.J.1    Fitz, S.D.2    Shekhar, A.3
  • 41
    • 0033054619 scopus 로고    scopus 로고
    • 1 receptors mediate the anxiolytic-like actions of neuropeptide Y in the social interaction test
    • DOI 10.1016/S0014-2999(99)00018-7, PII S0014299999000187
    • T.J. Sajdyk, M.G. Vandergriff, and D.R. Gehlert Amygdalar neuropeptide Y Y1 receptors mediate the anxiolytic-like actions of neuropeptide Y in the social interaction test Eur J Pharmacol 368 1999 143 147 (Pubitemid 29117135)
    • (1999) European Journal of Pharmacology , vol.368 , Issue.2-3 , pp. 143-147
    • Sajdyk, T.J.1    Vandergriff, M.G.2    Gehlert, D.R.3
  • 42
    • 0028069480 scopus 로고
    • Corticotropin-releasing factor and neuropeptide Y: Role in emotional integration
    • DOI 10.1016/0166-2236(94)90079-5
    • M. Heilig, G.F. Koob, R. Ekman, and K.T. Britton Corticotropin-releasing factor and neuropeptide Y: Role in emotional intgration Trends Neurosci 17 1994 80 85 (Pubitemid 24033179)
    • (1994) Trends in Neurosciences , vol.17 , Issue.2 , pp. 80-85
    • Heilig, M.1    Koob, G.F.2    Ekman, R.3    Britton, K.T.4
  • 43
    • 16444367602 scopus 로고    scopus 로고
    • Vasopressin and oxytocin excite distinct neuronal populations in the central amygdala
    • DOI 10.1126/science.1105636
    • D. Huber, P. Veinante, and R. Stoop Vasopressin and oxytocin excite distinct neuronal populations in the central amygdala Science 308 2005 245 248 (Pubitemid 40558858)
    • (2005) Science , vol.308 , Issue.5719 , pp. 245-248
    • Huber, D.1    Veinante, P.2    Stoop, R.3
  • 44
    • 77954758418 scopus 로고    scopus 로고
    • The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala
    • M. Roberto, M. Cruz, M. Bajo, G.R. Siggins, L.H. Parsons, and P. Schweitzer The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala Neuropsychopharmacology 35 2010 1962 1972
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1962-1972
    • Roberto, M.1    Cruz, M.2    Bajo, M.3    Siggins, G.R.4    Parsons, L.H.5    Schweitzer, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.