Synthesis and antimycobacterial evaluation of N'-(E)- heteroaromaticpyrazine-2-carbohydrazide derivatives

Medicinal Chemistry

Volumn 7, Issue 3, 2011, Pages 245-249

  Lima, C H S ^a,b   Henriques, M G M O ^a   Candea A L P ^a   Lourenco M C S ^a   Bezerra, F A F M ^a   Ferreira, M L ^a,b   Kaiser, C R ^b   De Souza, M V N ^a,b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Drugs; Pyrazine; Tuberculosis

Indexed keywords

ANTIMYCOBACTERIAL AGENT; N [(5 NITROFURAN 2 YL)METHYLENE]PYRAZINE 2 CARBOHYDRAZIDE; N' (FURAN 2 YLMETHYLENE)PYRAZINE 2 CARBOHYDRAZIDE; N' (PYRIDINE 2 YLMETHYLENE)PYRAZINE 2 CARBOHYDRAZIDE; N' (THIOPHEN 2 YLMETHYLENE)PYRAZINE 2 CARBOHYDRAZIDE; N' [(1H IMIDAZOL 2 YL)METHYLENE]PYRAZINE 2 CARBOHYDRAZIDE; N' [(1H PYRROL 2 YL)METHYLENE]PYRAZINE 2 CARBOHYDRAZIDE; N' [(5 NITROTHIOPHEN 2 YL)METHYLENE]PYRAZINE 2 CARBOHYDRAZIDE; N' [4 (PYRIDIN 2 YL)BENZYLIDENE]PYRAZINE 2 CARBOHYDRAZIDE; N' PHENYLMETHYLIDENE 2 PYRAZINECARBOHYDRAZIDE; PYRAZINAMIDE; PYRAZINE 2 CARBOHYDRAZIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CELL VIABILITY; CYTOTOXICITY; DRUG SYNTHESIS; MACROPHAGE; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTITUBERCULAR AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; HYDRAZINES; MACROPHAGES; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; PYRAZINES; STEREOISOMERISM;

EID: 79955767467     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340611795564303     Document Type: Article

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