Short tandem repeat and human leukocyte antigen mutations or losses confound engraftment and typing analysis in hematopoietic stem cell transplants

Human Immunology

Volumn 72, Issue 6, 2011, Pages 503-509

  Pereira, Shalini ^a   Vayntrub, Tamara ^b   Hiraki, Debra D ^c   Cherry, Athena M ^d   Arai, Sally ^c   Dvorak, Christopher C ^e   Grumet, F Carl ^c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b ROCHE MOLECULAR SYSTEMS   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chimerism; Engraftment; HLA; Transplantation; Typing

Indexed keywords

HLA ANTIGEN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CHROMOSOME ABERRATION; CORRELATION ANALYSIS; CYTOGENETICS; ENGRAFTMENT; GENE LOCUS; GENE MUTATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA TYPING; MOLECULAR TYPING; MYELOFIBROSIS; PRIORITY JOURNAL; SHORT TANDEM REPEAT;

ADULT; CHROMOSOME ABERRATIONS; DNA MUTATIONAL ANALYSIS; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; INCIDENCE; LEUKEMIA, MYELOID, ACUTE; MALE; MICROSATELLITE REPEATS; MUTATION; PRIMARY MYELOFIBROSIS; TRANSPLANTATION TOLERANCE;

EID: 79955758741     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2011.03.003     Document Type: Article

References (24)

1. Saunders K., Czepulkowski B., Sivalingam R., Hayes J.P., Aldouri M., Sekhar M., et al. Isochromosome of a deleted 20q: a rare but recurrent chromosome abnormality in myelodysplastic syndromes. Cancer Genet Cytogenet 2005, 156:154-157.
2. Eshleman J.R., Markowitz S.D. Microsatellite instability in inherited and sporadic neoplasms. Curr Opin Oncol 1995, 7:83-89.
3. Boyer J.C., Risinger J.I., Farber R.A. Stability of microsatellites in myeloid neoplasias. Cancer Genet Cytogenet 1998, 106:54-61.
4. Tasaka T., Lee S., Spira S., Takeuchi S., Nagai M., Takahara J., et al. Microsatellite instability during the progression of acute myelocytic leukaemia. Br J Haematol 1997, 98:219-221.
5. Krishnaswamy S., Krishnaswamy R., Hiraki D., Grument F.C. HLA-DRB typing using an in-house ELISA based oligoprobe assay. Molecular Typing 2000 Technical Manual for Histocompatiblity Laboratories 2000, B.3.31. South Eastern Organ Procurement Foundation, Richmond, VA. 2nd ed.
6. Auffermann-Gretzinger S., Lossos I.S., Vayntrub T.A., Leong W., Grumet F.C., Blume K.G., et al. Rapid establishment of dendritic cell chimerism in allogeneic hematopoietic cell transplant recipients. Blood 2002, 99:1442-1448.
7. Baron F., Baker J.E., Storb R., Gooley T.A., Sandmaier B.M., Maris M.B., et al. Kinetics of engraftment in patients with hematologic malignancies given allogeneic hematopoietic cell transplantation after nonmyeloablative conditioning. Blood 2004, 104:2254-2262.
8. Millan M.T., Shizuru J.A., Hoffmann P., Dejbakhsh-Jones S., Scandling J.D., Grumet F.C., et al. Mixed chimerism and immunosuppressive drug withdrawal after HLA-mismatched kidney and hematopoietic progenitor transplantation. Transplantation 2002, 73:1386-1391.
9. Jordanova E.S., Riemersma S.A., Philippo K., Giphart-Gassler M., Schuuring E., Kluin P.M., et al. Hemizygous deletions in the HLA region account for loss of heterozygosity in the majority of diffuse large B-cell lymphomas of the testis and the central nervous system. Genes Chromosomes Cancer 2002, 35:38-48.
10. Riemersma S.A., Jordanova E.S., Schop R.F., Philippo K., Looijenga L.H., Schuuring E., et al. Extensive genetic alterations of the HLA region, including homozygous deletions of HLA class II genes in B-cell lymphomas arising in immune-privileged sites. Blood 2000, 96:3569-3577.
11. Maleno I., Cabrera C.M., Cabrera T., Paco L., López-Nevot M.A., Collado A., et al. Distribution of HLA class I altered phenotypes in colorectal carcinomas: high frequency of HLA haplotype loss associated with loss of heterozygosity in chromosome region 6p21. Immunogenetics 2004, 56:244-253.
12. Feenstra M., Veltkamp M., van Kuik J., Wiertsema S., Slootweg P., van den Tweel J., et al. HLA class I expression and chromosomal deletions at 6p and 15q in head and neck squamous cell carcinomas. Tissue Antigens 1999, 54:235-245.
13. Bodmer W.F., Browning M.J., Krausa P., Rowan A., Bicknell D.C., Bodmer J.G., et al. Tumor escape from immune response by variation in HLA expression and other mechanisms. Ann N Y Acad Sci 1993, 690:42-49.
14. Villalobos I.B., Takahashi Y., Akatsuka Y., Muramatsu H., Nishio N., Hama A., et al. Relapse of leukemia with loss of mismatched HLA resulting from uniparental disomy after haploidentical hematopoietic stem cell transplantation. Blood 2009, 115:3158-3161.
15. Vago L., Perna S.K., Zanussi M., Mazzi B., Barlassina C., Stanghellini M.T., et al. Loss of mismatched HLA in leukemia after stem-cell transplantation. N Engl J Med 2009, 361:478-488.
16. Paschen A., Méndez R.M., Jimenez P., Sucker A., Ruiz-Cabello F., Song M., et al. Complete loss of HLA class I antigen expression on melanoma cells: a result of successive mutational events. Int J Cancer 2003, 103:759-767.
17. García-Lora A., Algarra I., Collado A., Garrido F. Tumour immunology, vaccination and escape strategies. Eur J Immunogenet 2003, 30:177-183.
18. Kaneko H., Horiike S., Inazawa J., Nakai H., Misawa S. Microsatellite instability is an early genetic event in myelodysplastic syndrome. Blood 1995, 86:1236-1237.
19. Neuman W.L., Rubin C.M., Rios R.B., Larson R.A., Le Beau M.M., Rowley J.D., et al. Chromosomal loss and deletion are the most common mechanisms for loss of heterozygosity from chromosomes 5 and 7 in malignant myeloid disorders. Blood 1992, 79:1501-1510.
20. Ribeiro E.M., Rodriguez J.M., Cóser V.M., Sotero M.G., Fonseca Neto J.M., Pasquini R., et al. Microsatellite instability and cytogenetic survey in myeloid leukemias. Braz J Med Biol Res 2002, 35:153-159.
21. Soekarman D., von Lindern M., Daenen S., de Jong B., Fonatsch C., Heinze B., et al. The translocation (6;9)(p23;q34) shows consistent rearrangement of two genes and defines a myeloproliferative disorder with specific clinical features. Blood 1992, 79:2990-2997.
22. Lee S., Chen J., Zhou G., Shi R.Z., Bouffard G.G., Kocherginsky M., et al. Gene expression profiles in acute myeloid leukemia with common translocations using SAGE. Proc Natl Acad Sci U S A 2006, 103:1030-1035.
23. Yamamoto K., Hato A., Minagawa K., Yakushijin K., Urahama N., Gomyo H., et al. Unbalanced translocation der(11)t(11;12)(q23;q13): a new recurrent cytogenetic aberration in myelodysplastic syndrome with a complex karyotype. Cancer Genet Cytogenet 2004, 155:67-73.
24. Gargallo P., Hagemeijer A., Vassallu P., Kornblihtt L., Heller P., Molinas F., et al. Insertion (4;11)(q27;q24q21) in a patient with essential thrombocythemia with progression to myelofibrosis. Cancer Genet Cytogenet 2004, 154:72-76.