Chronic cocaine self-administration in rhesus monkeys: Impact on associative learning, cognitive control, and working memory

Journal of Neuroscience

Volumn 31, Issue 13, 2011, Pages 4926-4934

  Porter, Jessica N ^a   Olsen, Adam S ^b   Gurnsey, Kate ^b   Dugan, Brian P ^b   Jedema, Hank P ^b   Bradberry, Charles W ^a,b,c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c Veterans Affairs Pittsburgh   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCAINE DEPENDENCE; COGNITIVE DEFECT; CONTROLLED STUDY; EXECUTIVE FUNCTION; LONGITUDINAL STUDY; MALE; MEMORY DISORDER; MENTAL TASK; NONHUMAN; PERCEPTIVE DISCRIMINATION; PRIORITY JOURNAL; REWARD; RHESUS MONKEY; STATE DEPENDENT LEARNING; WORKING MEMORY;

ANIMALS; ASSOCIATION LEARNING; COCAINE; COCAINE-RELATED DISORDERS; COGNITION; MACACA MULATTA; MALE; MEMORY, SHORT-TERM; PSYCHOMOTOR PERFORMANCE; RANDOM ALLOCATION; SELF ADMINISTRATION;

EID: 79955734836     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5426-10.2011     Document Type: Article

References (56)

1. Aharonovich E, Hasin DS, Brooks AC, Liu X, Bisaga A, Nunes EV (2006) Cognitive deficits predict low treatment retention in cocaine dependent patients. Drug Alcohol Depend 81:313-322.
2. Bechara A (2005) Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective. Nat Neurosci 8:1458-1463.
3. Bechara A, Martin EM (2004) Impaired decision making related to working memory deficits in individuals with substance addictions. Neuropsychology 18:152-162.
4. Belin D, Mar AC, Dalley JW, Robbins TW, Everitt BJ (2008) High impulsivity predicts the switch to compulsive cocaine-taking. Science 320:1352-1355.
5. Bolla KI, Rothman R, Cadet JL (1999) Dose-related neurobehavioral effects of chronic cocaine use. J Neuropsychiatry Clin Neurosci 11:361-369.
6. Butter CM (1969) Perseveration in distinction and in discrimination reversal tasks following selective frontal ablations in Macaca mulatta. Physiol Behav 4:163-171.
7. Castellanos FX, Sonuga-Barke EJ, Scheres A, Di Martino A, Hyde C, Walters JR (2005) Varieties of attention-deficit/hyperactivity disorder-related intra-individual variability. Biol Psychiatry 57:1416-1423.
8. Clarke HF, Robbins TW, Roberts AC (2008) Lesions of the medial striatum in monkeys produce perseverative impairments during reversal learning similar to those produced by lesions of the orbitofrontal cortex. J Neurosci 28:10972-10982.
9. Deroche-Gamonet V, Belin D, Piazza PV (2004) Evidence for addiction-like behavior in the rat. Science 305:1014-1017.
10. Dias R, Robbins TW, Roberts AC (1996) Dissociation in prefrontal cortex of affective and attentional shifts. Nature 380:69-72.
11. Duncan J (2001) An adaptive coding model of neural function in prefrontal cortex. Nat Rev Neurosci 2:820-829.
12. Elliott R, Dolan RJ (1999) Differential neural responses during performance of matching and nonmatching to sample tasks at two delay intervals. J Neurosci 19:5066-5073.
13. Ersche KD, Roiser JP, Robbins TW, Sahakian BJ (2008) Chronic cocaine but not chronic amphetamine use is associated with perseverative responding in humans. Psychopharmacology (Berl) 197:421-431.
14. Fellows LK, Farah MJ (2003) Ventromedial frontal cortex mediates affective shifting in humans: evidence from a reversal learning paradigm. Brain 126:1830-1837.
15. Fillmore MT, Rush CR (2006) Polydrug abusers display impaired discrimination-reversal learning in a model of behavioural control. J Psychopharmacol 20:24-32.
16. Franklin TR, Acton PD, Maldjian JA, Gray JD, Croft JR, Dackis CA, O'Brien CP, Childress AR (2002) Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients. Biol Psychiatry 51:134-142.
17. Garavan H, Hester R (2007) The role of cognitive control in cocaine dependence. Neuropsychol Rev 17:337-345.
18. George O, Mandyam CD, Wee S, Koob GF (2008) Extended access to cocaine self-administration produces long-lasting prefrontal cortexdependent working memory impairments. Neuropsychopharmacology 33:2474-2482.
19. Gomez G, Jedema HP, Gurnsey K, Bradberry CW (2010) The effect of cocaine self administration on sleep in rhesus monkeys. Society Neurosci Abstr 36:506.20.
20. Grant S, Contoreggi C, London ED (2000) Drug abusers show impaired performance in a laboratory test of decision making. Neuropsychologia 38:1180-1187.
21. Harlow HF (1949) The formation of learning sets. Psychol Rev 56:51-65.
22. Hoff AL, Riordan H, Morris L, Cestaro V, Wieneke M, Alpert R, Wang GJ, Volkow N (1996) Effects of crack cocaine on neurocognitive function. Psychiatry Res 60:167-176.
23. Hornak J, O'Doherty J, Bramham J, Rolls ET, Morris RG, Bullock PR, Polkey CE (2004) Reward-related reversal learning after surgical excisions in orbito-frontal or dorsolateral prefrontal cortex in humans. J Cogn Neurosci 16:463-478.
24. Izquierdo A, Suda RK, Murray EA (2004) Bilateral orbital prefrontal cortex lesions in rhesus monkeys disrupt choices guided by both reward value and reward contingency. J Neurosci 24:7540-7548.
25. Jentsch JD, Olausson P, De La Garza R 2nd, Taylor JR (2002) Impairments of reversal learning and response perseveration after repeated, intermittent cocaine administrations to monkeys. Neuropsychopharmacology 26:183-190.
26. Kalivas PW, Volkow ND (2005) The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatry 162:1403-1413.
27. Kennerley SW, Wallis JD (2009) Reward-dependent modulation of working memory in lateral prefrontal cortex. J Neurosci 29:3259-3270.
28. Kübler A, Murphy K, Garavan H (2005) Cocaine dependence and attention switching within and between verbal and visuospatial working memory. Eur J Neurosci 21:1984-1992.
29. Letchworth SR, Nader MA, Smith HR, Friedman DP, Porrino LJ (2001) Progression of changes in dopamine transporter binding site density as a result of cocaine self-administration in rhesus monkeys. J Neurosci 21:2799-2807.
30. Liu S, Heitz RP, Sampson AR, Zhang W, Bradberry CW (2008) Evidence of temporal cortical dysfunction in rhesus monkeys following chronic cocaine self-administration. Cereb Cortex 18:2109-2116.
31. London ED, Ernst M, Grant S, Bonson K, Weinstein A (2000) Orbitofrontal cortex and human drug abuse: functional imaging. Cereb Cortex 10:334-342.
32. Maunsell JH (2004) Neuronal representations of cognitive state: reward or attention? Trends Cogn Sci 8:261-265.
33. Murray EA, Izquierdo A (2007) Orbitofrontal cortex and amygdala contributions to affect and action in primates. AnnN Y Acad Sci 1121:273-296.
34. Nader MA, Daunais JB, Moore T, Nader SH, Moore RJ, Smith HR, Friedman DP, Porrino LJ (2002) Effects of cocaine self-administration on striatal dopamine systems in rhesus monkeys: initial and chronic exposure. Neuropsychopharmacology 27:35-46.
35. Nader MA, Morgan D, Gage HD, Nader SH, Calhoun TL, Buchheimer N, Ehrenkaufer R, Mach RH (2006) PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys. Nat Neurosci 9:1050-1056.
36. Olsen AS, Porter JN, Dugan BP, Gurnsey K, Jedema HP, Bradberry CW (2009) Cocaine self-administration impairs attention as shown by in-creased intra-subject response time variability in rhesus monkeys. Society Neurosci Abstr 35:158.5.
37. O'Malley S, Adamse M, Heaton RK, Gawin FH (1992) Neuropsychological impairment in chronic cocaine abusers. Am J Drug Alcohol Abuse 18:131-144.
38. Otto T, Eichenbaum H (1992) Complementary roles of the orbital prefrontal cortex and the perirhinal-entorhinal cortices in an odor-guided delayed-nonmatching-to-sample task. Behav Neurosci 106:762-775.
39. Pace-Schott EF, Morgan PT, Malison RT, Hart CL, Edgar C, Walker M, Stickgold R (2008) Cocaine users differ from normals on cognitive tasks which show poorer performance during drug abstinence. Am J Drug Alcohol Abuse 34:109-121.
40. Patkar AA, Murray HW, Mannelli P, Gottheil E, Weinstein SP, Vergare MJ (2004) Pre-treatment measures of impulsivity, aggression and sensation seeking are associated with treatment outcome for African-American cocaine-dependent patients. J Addict Dis 23:109-122.
41. Porter JN, Jedema HP, Dugan BP, Gomez G, Gurnsey K, Bradberry CW (2010) Long lasting increases in distractibility in rhesus monkeys following chronic cocaine self-administration. Soc Neurosci Abstr 36:506-519.
42. Rogers RD, Robbins TW (2001) Investigating the neurocognitive deficits associated with chronic drug misuse. Curr Opin Neurobiol 11:250-257.
43. Sarter M, Gehring WJ, Kozak R (2006) More attention must be paid: the neurobiology of attentional effort. Brain Res Rev 51:145-160.
44. Schoenbaum G, Shaham Y (2008) The role of orbitofrontal cortex in drug addiction: a review of preclinical studies. Biol Psychiatry 63:256-262.
45. Schoenbaum G, Saddoris MP, Ramus SJ, Shaham Y, Setlow B (2004) Cocaine-experienced rats exhibit learning deficits in a task sensitive to orbitofrontal cortex lesions. Eur J Neurosci 19:1997-2002.
46. Schoenbaum G, Roesch MR, Stalnaker TA (2006) Orbitofrontal cortex, decision-making and drug addiction. Trends Neurosci 29:116-124.
47. Schultz W (2007) Behavioral dopamine signals. Trends Neurosci 30: 203-210.
48. Tarter RE, Kirisci L, Feske U, Vanyukov M (2007) Modeling the pathways linking childhood hyperactivity and substance use disorder in young adulthood. Psychol Addict Behav 21:266-271.
49. Teichner G, Horner MD, Roitzsch JC, Herron J, Thevos A (2002) Substance abuse treatment outcomes for cognitively impaired and intact outpatients. Addict Behav 27:751-763.
50. Verdejo-Garcia A, Perez-Garcia M (2007) Profile of executive deficits in cocaine and heroin polysubstance users: common and differential effects on separate executive components. Psychopharmacology (Berl) 190:517-530.
51. Volkow ND, Fowler JS, Wang GJ, Hitzemann R, Logan J, Schlyer DJ, Dewey SL, Wolf AP (1993) Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse 14:169-177.
52. Volkow ND, Wang GJ, Fowler JS, Telang F (2008) Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology. Philos Trans R Soc Lond B Biol Sci 363:3191-3200.
53. Wallis JD (2007) Orbitofrontal cortex and its contribution to decisionmaking. Annu Rev Neurosci 30:31-56.
54. Weiss F, Markou A, Lorang MT, Koob GF (1992) Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration. Brain Res 593:314-318.
55. Wilson FA, Scalaidhe SP, Goldman-Rakic PS (1993) Dissociation of object and spatial processing domains in primate prefrontal cortex. Science 260:1955-1958.
56. Wojnicki FH, Bacher JD, Glowa JR (1994) Use of subcutaneous vascular access ports in rhesus monkeys. Lab Anim Sci 44:491-494.