Nodulogenesis and goitrogenesis;Nodulogenesis et goitrogenèse

Annales d'Endocrinologie

Volumn 72, Issue 2, 2011, Pages 117-119

  Paschke, R ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Goiter; H2O2; Iodine deficiency; Mutagenesis; Nodules; Somatic mutations

Indexed keywords

THYROID HORMONE; THYROTROPIN; THYROTROPIN RECEPTOR;

ARTICLE; DIZYGOTIC TWINS; ENVIRONMENTAL FACTOR; EUTHYROIDISM; GENE INTERACTION; GENE MUTATION; GENETIC HETEROGENEITY; GENETIC PREDISPOSITION; GOITER; GOITROGENESIS; HUMAN; HYPERTHYROIDISM; HYPOTHYROIDISM; INHERITANCE; IRON DEFICIENCY; MONOZYGOTIC TWINS; NODULOGENESIS; PATHOGENESIS; PENETRANCE; THYROID HYPERPLASIA; THYROID NODULE;

FEMALE; GENETIC PREDISPOSITION TO DISEASE; GOITER, NODULAR; HUMANS; HYDROGEN PEROXIDE; IODINE; MALE; MUTAGENESIS; THYROID NODULE;

EID: 79955732888     PISSN: 00034266     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ando.2011.03.015     Document Type: Article

References (25)

1. Chan J.K.C., Hirokawa M., Evans H., Williams E.D., Osamura Y., Cady B., et al. Follicular adenoma. WHO classification of tumours. Pathology and genetics of tumours of endocrine organs 2004, 98-103. IARC Press, Lyon. R.A. DeLellis, R.V. Lloyd, P.U. Heitz, C. Eng (Eds.).
2. Belfiore A., La Rosa G.L., La Porta G.A., et al. Cancer risk in patients with cold thyroid nodules: relevance of iodine intake, sex, age, and multinodularity. Am J Med 1992, 93:363-369.
3. Knudsen N., Perrild H., Christiansen E., et al. Thyroid structure and size and two-year follow-up of solitary cold thyroid nodules in an unselected population with borderline iodine deficiency. Eur J Endocrinol 2000, 142:224-230.
4. Hegedüs L., Bonnema S.J., Bennedbæk F.N. Management of simple nodular goiter: current status and future perspectives. Endocr Rev 2003, 24:102-132.
5. Berghout A., Wiersinga W.M., Smits N.J., et al. Interrelationships between age, thyroid volume, thyroid nodularity, and thyroid function in patients with sporadic nontoxic goiter. Am J Med 1990, 89:602-608.
6. Knudsen N., Laurberg P., Perrild H., et al. Risk factors for goiter and thyroid nodules. Thyroid 2002, 12:879-888.
7. Scanelli G. Lithium thyrotoxicosis. Report of a case and review of the literature. Recenti Prog Med 2002, 93:100-103.
8. Brix T.H., Hansen P.S., Kyvik K.O., et al. Cigarette smoking and risk of clinically overt thyroid disease: a population-based twin case-control study. Arch Intern Med 2000, 160:661-666.
9. Brix T.H., Kyvik K.O., Hegedus L. Major role of genes in the etiology of simple goiter in females: a population-based twin study. J Clin Endocrinol Metab 1999, 84:3071-3075.
10. Knudsen N., Bulow I., Laurberg P., et al. Parity is associated with increased thyroid volume solely among smokers in an area with moderate to mild iodine deficiency. Eur J Endocrinol 2002, 146:39-43.
11. Krohn K., Fuhrer D., Bayer Y., et al. Molecular pathogenesis of euthyroid and toxic multinodular goiter. Endocr Rev 2005, 26:504-524.
12. Hansen P.S., Brix T.H., Bennedbaek F.N., et al. Genetic and environmental causes of individual differences in thyroid size: a study of healthy Danish twins. J Clin Endocrinol Metab 2004, 89:2071-2077.
13. Bayer Y., Neumann S., Meyer B., et al. Genome-wide linkage analysis reveals evidence for four new susceptibility loci for familial euthyroid goiter. J Clin Endocrinol Metab 2004, 89:4044-4052.
14. Böttcher Y., Eszlinger M., Tönjes A., Paschke R. The genetics of euthyroid familial goiter. Trends Endocrinol Metab 2005, 16(7):314-3192005.
15. Bignell G.R., Canzian F., Shayeghi M., et al. Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer. Am J Hum Genet 1997, 61:1123-1130.
16. Neumann S., Bayer Y., Reske A., et al. Further indications for genetic heterogeneity of euthyroid familial goiter. J Mol Med 2003, 81:736-745.
17. Brix T.H., Hegedüs L. Genetic and environmental factors in the aetiology of simple goitre. Ann Med 2000, 32:153-156.
18. Geerdsen J.P., Hee P. Nontoxic goitre. I. Surgical complications and longterm prognosis. Acta Chir Scand 1982, 148:221-224.
19. Piraneo S., Vitri P., Galimberti A., et al. Ultrasonographic surveillance after surgery for euthyroid goitre in patients treated or not with thyroxine. Eur J Surg 1997, 163:21-26.
20. Neumann S., Willgerodt H., Ackermann F., et al. Linkage of familial euthyroid goiter to the multinodular goiter-1 locus and exclusion of the candidate genes thyroglobulin, thyroperoxidase, and Na+/I- symporter. J Clin Endocrinol Metab 1999, 84:3750-3756. [In Process Citation].
21. Capon F., Tacconelli A., Giardina E., et al. Mapping a dominant form of multinodular goiter to chromosome Xp22. Am J Hum Genet 2000, 67:1004-1007.
22. Many M.C., Denef J.F., Hamudi S., et al. Effects of iodide and thyroxine on iodine-deficient mouse thyroid: a morphological and functional study. J Endocrinol 1986, 110:203-210.
23. Raspe E., Dumont J.E. Tonic modulation of dog thyrocyte H2O2 generation and I- uptake by thyrotropin through the cyclic adenosine 3',5'-monophosphate cascade. Endocrinology 1995, 136:965-973.
24. Krohn K., Maier J., Paschke R. Mechanisms of disease: hydrogen peroxide. DNA damage and mutagenesis in the development of thyroid tumors. Nat Clin Pract Endocrinol Metab 2007, 3:713-720.
25. Krohn K., Wohlgemuth S., Gerber H., et al. Hot microscopic areas of iodine deficient euthyroid goiters contain constitutively activating TSH receptor mutations. J Pathol 2000, 192:37-42.