Physiology of the small bowel: A new approach using MRI and proposal for a new metric of function

Medical Hypotheses

Volumn 76, Issue 6, 2011, Pages 834-839

  Toms, Andoni P ^a   Farghal, Aser ^a   Kasmai, Bahman ^b   Bagnall, Anthony ^c   Malcolm, Paul N ^b  

^a Norwich Radiology Academy   (United Kingdom)

^b NORFOLK AND NORWICH UNIVERSITY HOSPITAL   (United Kingdom)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DIAGNOSTIC IMAGING; HUMAN; HYPOTHESIS; INTESTINE FUNCTION; INTESTINE MOTILITY; INTESTINE PRESSURE; INTESTINE TRANSIT TIME; MATHEMATICAL MODEL; NUCLEAR MAGNETIC RESONANCE IMAGING; PARAMETER; PERISTALSIS; QUANTITATIVE ANALYSIS; RELIABILITY; SMALL INTESTINE; TECHNIQUE; THREE DIMENSIONAL IMAGING; VALIDITY;

GASTROINTESTINAL MOTILITY; HUMANS; INTESTINE, SMALL; MAGNETIC RESONANCE IMAGING;

EID: 79955714426     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2011.02.031     Document Type: Article

References (60)

1. Schwartz M.P., Samsom M., Renooij W., van Steenderen L.W., Benninga M.A., van Geenen E.M., et al. Small bowel motility affects glucose absorption in a healthy man. Diabetes Care 2002, 25(10):1857-1861.
2. Imam H., Sanmiguel C., Larive B., Bhat Y., Soffer E. Study of intestinal flow by combined videofluoroscopy, manometry, and multiple intraluminal impedance. Am J Physiol Gastrointest Liver Physiol 2004, 286(2):G263-G270.
3. Lundqvist H., Jung B., Gustavsson S., Nilsson F., Lundqvist G. Analyses of small bowel propulsion, ileo-caecal passage and serum gastrin after truncal vagotomy. A methodological study in the rat with continuous intraduodenal infusion. Acta Chir Scand 1975, 141(4):298-303.
4. Argenyi E.E., Soffer E.E., Madsen M.T., Berbaum K.S., Walkner W.O. Scintigraphic evaluation of small bowel transit in healthy subjects: inter- and intrasubject variability. Am J Gastroenterol 1995, 90(6):938-942.
5. Grybäck P., Jacobsson H., Blomquist L., Schnell P.O., Hellström P.M. Scintigraphy of the small intestine: a simplified standard for study of transit with reference to normal values. Eur J Nucl Med Mol Imaging 2002, 29(1):39-45.
6. Sadik R., Abrahamsson H., Stotzer P.O. Gender differences in gut transit shown with a newly developed radiological procedure. Scand J Gastroenterol 2003, 38(1):36-42.
7. Graff J., Brinch K., Madsen J.L. Gastrointestinal mean transit times in young and middle-aged healthy subjects. Clin Physiol 2001, 21(2):253-259.
8. Bennink R., Peeters M., Van den Maegdenbergh V., Geypens B., Rutgeerts P., De Roo M., et al. Evaluation of small-bowel transit for solid and liquid test meal in healthy men and women. Eur J Nucl Med 1999, 26(12):1560-1566.
9. Malagelada J.R., Robertson J.S., Brown M.L., Remington M., Duenes J.A., Thomforde G.M., et al. Intestinal transit of solid and liquid components of a meal in health. Gastroenterology 1984, 87(6):1255-1263.
10. Hammer J., Hammer K., Kletter K. Lipids infused into the jejunum accelerate small intestinal transit but delay ileocolonic transit of solids and liquids. Gut 1998, 43(1):111-116.
11. Hebden J.M., Blackshaw P.E., Perkins A.C., D'Amato M., Spiller R.C. Small bowel transit of a bran meal residue in humans: sieving of solids from liquids and response to feeding. Gut 1998, 42(5):685-689.
12. Lin H.C., Zhao X.T., Wang L. Jejunal brake: inhibition of intestinal transit by fat in the proximal small intestine. Dig Dis Sci 1996, 41(2):326-329.
13. Carlson G.M., Bedi B.S., Code C.F. Mechanism of propagation of intestinal interdigestive myoelectric complex. Am J Physiol 1972, 222(4):1027-1030.
14. Penning C., Gielkens H.A., Hemelaar M., Lamers C.B., Masclee A.A. Reproducibility of antroduodenal motility during prolonged ambulatory recording. Neurogastroenterol Motil 2001, 13(2):133-141.
15. McCoy E.J., Baker R.D. Effect of feeding on electrical activity of dog's small intestine. Am J Physiol 1968, 214(6):1291-1295.
16. Kerlin P., Zinsmeister A., Phillips S. Relationship of motility to flow of contents in the human small intestine. Gastroenterology 1982, 82(4):701-706.
17. Castedal M., Björnsson E., Abrahamsson H. Postprandial peristalsis in the human duodenum. Neurogastroenterol Motil 1998, 10(3):227-233.
18. Andrews J.M., Doran S.M., Hebbard G.S., Malbert C.H., Horowitz M., Dent J. Nutrient-induced spatial patterning of human duodenal motor function. Am J Physiol Gastrointest Liver Physiol 2001, 280(3):G501-G509.
19. von Schönfeld J., Evans D.F., Renzing K., Castillo F.D., Wingate D.L. Human small bowel motor activity in response to liquid meals of different caloric value and different chemical composition. Dig Dis Sci 1998, 43(2):265-269.
20. Kumar D., Wingate D., Ruckebusch Y. Circadian variation in the propagation velocity of the migrating motor complex. Gastroenterology 1986, 91(4):926-930.
21. Brinch K., Larsson H.B., Madsen J.L. A deconvolution technique for processing small intestinal transit data. Eur J Nucl Med 1999, 26(3):272-276.
22. Graff J., Brinch K., Madsen J.L. Simplified scintigraphic methods for measuring gastrointestinal transit times. Clin Physiol 2000, 20(4):262-266.
23. Mojaverian P., Chan K., Desai A., John V. Gastrointestinal transit of a solid indigestible capsule as measured by radiotelemetry and dual gamma scintigraphy. Pharm Res 1989, 6(8):719-724.
24. Hung G., Tsai C., Lin W. Development of a new method for small bowel transit study. Ann Nucl Med 2006, 20(6):387-392.
25. McIntyre A., Vincent R.M., Perkins A.C., Spiller R.C. Effect of bran, ispaghula, and inert plastic particles on gastric emptying and small bowel transit in humans: the role of physical factors. Gut 1997, 40(2):223-227.
26. Vincent R., Roberts A., Frier M., Perkins A.C., MacDonald I.A., Spiller R.C. Effect of bran particle size on gastric emptying and small bowel transit in humans: a scintigraphic study. Gut 1995, 37(2):216-219.
27. Adkin D.A., Davis S.S., Sparrow R.A., Huckle P.D., Phillips A.J., Wilding I.R. The effects of pharmaceutical excipients on small intestinal transit. Br J Clin Pharmacol 1995, 39(4):381-387.
28. von der Ohe M.R., Camilleri M. Measurement of small bowel and colonic transit: indications and methods. Mayo Clin Proc 1992, 67(12):1169-1179.
29. Fadda H.M., McConnell E.L., Short M.D., Basit A.W. Meal-induced acceleration of tablet transit through the human small intestine. Pharm Res 2009, 26(2):356-360.
30. Hebden J.M., Blackshaw E., D'Amato M., Perkins A.C., Spiller R.C. Abnormalities of GI transit in bloated irritable bowel syndrome: effect of bran on transit and symptoms. Am J Gastroenterol 2002, 97(9):2315-2320.
31. Basit A.W., Newton J.M., Short M.D., Waddington W.A., Ell P.J., Lacey L.F. The effect of polyethylene glycol 400 on gastrointestinal transit: implications for the formulation of poorly-water soluble drugs. Pharm Res 2001, 18(8):1146-1150.
32. Nolan D., Traill Z. The current role of the barium examination of the small intestine. Clin Radiol 1997, 52(11):809-820.
33. Rubesin S., Maglinte D. Double-contrast barium enema technique. Radiol Clin North Am 2003, 41(2):365-376.
34. Stehling M.K., Evans D.F., Lamont G., Ordidge R.J., Howseman A.M., Chapman B., et al. Gastrointestinal tract: dynamic MR studies with echo-planar imaging. Radiology 1989, 171(1):41-46.
35. Cronin C.G., Lohan D.G., Browne A.M., Alhajeri A.N., Roche C., Murphy J.M. MR enterography in the evaluation of small bowel dilation. Clin Radiol 2009, 64(10):1026-1034.
36. Gourtsoyiannis N., Papanikolaou N., Grammatikakis J., Maris T., Prassopoulos P. MR imaging of the small bowel with a true-FISP sequence after enteroclysis with water solution. Invest Radiol 2000, 35(12):707-711.
37. Umschaden H.W., Szolar D., Gasser J., Umschaden M., Haselbach H. Small-bowel disease: comparison of MR enteroclysis images with conventional enteroclysis and surgical findings. Radiology 2000, 215(3):717-725.
38. Van Weyenberg S.J.B., Meijerink M.R., Jacobs M.A.J.M., Van der Peet D.L., Van Kuijk C., Mulder C.J.J., et al. MR enteroclysis in the diagnosis of small-bowel neoplasms. Radiology 2010, 254(3):765-773.
39. Fidler J.L., Guimaraes L., Einstein D.M. MR imaging of the small bowel. Radiographics 2009, 29(6):1811-1825.
40. Cronin C.G., Lohan D.G., Browne A.M., Roche C., O'Keeffe D., Murphy J.M. MR small-bowel follow-through for investigation of suspected pediatric small-bowel pathology. AJR Am J Roentgenol 2009, 192(5):1239-1245.
41. Buhmann-Kirchhoff S., Lang R., Kirchhoff C., Steitz H.O., Jauch K.W., Reiser M., et al. Functional cine MR imaging for the detection and mapping of intraabdominal adhesions: method and surgical correlation. Eur Radiol 2008, 18(6):1215-1223.
42. Mussack T., Fischer T., Ladurner R., Gangkofer A., Bensler S., Hallfeldt K.K., et al. Cine magnetic resonance imaging vs high-resolution ultrasonography for detection of adhesions after laparoscopic and open incisional hernia repair: a matched pair pilot analysis. Surg Endosc 2005, 19(12):1538-1543.
43. Lienemann A., Sprenger D., Steitz H.O., Korell M., Reiser M. Detection and mapping of intraabdominal adhesions by using functional cine MR imaging: preliminary results. Radiology 2000, 217(2):421-425.
44. Giusti S, Faggioni L, Neri E, Fruzzetti E, Nardini L, Marchi S, et al. Dynamic MRI of the small bowel: usefulness of quantitative contrast-enhancement parameters and time-signal intensity curves for differentiating between active and inactive Crohn's disease. Abdom Imaging [Internet]; 2010 May 28 [cited 2010 July 14]; available from: http://www.ncbi.nlm.nih.gov/pubmed/20509025.
45. Oommen J, Oto A. Contrast-enhanced MRI of the small bowel in Crohn's disease. Abdom Imaging [Internet]; 2010 May 11 [cited 2010 July 14]; available from: http://www.ncbi.nlm.nih.gov/pubmed/20458477.
46. Taylor S.A., Punwani S., Rodriguez-Justo M., Bainbridge A., Greenhalgh R., De Vita E., et al. Mural Crohn disease: correlation of dynamic contrast-enhanced MR imaging findings with angiogenesis and inflammation at histologic examination - pilot study. Radiology 2009, 251(2):369-379.
47. Pupillo V.A., Di Cesare E., Frieri G., Limbucci N., Tanga M., Masciocchi C. Assessment of inflammatory activity in Crohn's disease by means of dynamic contrast-enhanced MRI. Radiol Med 2007, 112(6):798-809.
48. Marciani L., Cox E.F., Hoad C.L., Pritchard S., Totman J.J., Foley S., et al. Postprandial changes in small bowel water content in healthy subjects and patients with irritable bowel syndrome. Gastroenterology 2010, 138(2):469-477. [477.e1].
49. Froehlich J.M., Patak M.A., von Weymarn C., Juli C.F., Zollikofer C.L., Wentz K. Small bowel motility assessment with magnetic resonance imaging. J Magn Reson Imaging 2005, 21(4):370-375.
50. Marciani L., Young P., Wright J., Moore R.J., Evans D.F., Spiller R.C., et al. Echoplanar imaging in GI clinical practice: assessment of gastric emptying and antral motility in four patients. J Magn Reson Imaging 2000, 12(2):343-346.
51. Marciani L., Manoj P., Hills B.P., Moore R.J., Young P., Fillery-Travis A., et al. Echo-planar imaging relaxometry to measure the viscosity of a model meal. J Magn Reson 1998, 135(1):82-86.
52. Marciani L., Gowland P.A., Spiller R.C., Manoj P., Moore R.J., Young P., et al. Gastric response to increased meal viscosity assessed by echo-planar magnetic resonance imaging in humans. J Nutr 2000, 130(1):122-127.
53. Marciani L., Gowland P.A., Spiller R.C., Manoj P., Moore R.J., Young P., et al. Effect of meal viscosity and nutrients on satiety, intragastric dilution, and emptying assessed by MRI. Am J Physiol Gastrointest Liver Physiol 2001, 280(6):G1227-G1233.
54. Bennett J., Rhodes M., Malcolm P., Dainty J., Simpson B., Johnson I., et al. Assessment of the relationship between post-meal satiety, gastric volume and gastric emptying after Swedish adjustable gastric banding. A pilot study using magnetic resonance imaging to assess postsurgery gastric function. Obesity Surgery 2009, 19(6):757-763.
55. Marciani L., Gowland P.A., Fillery-Travis A., Manoj P., Wright J., Smith A., et al. Assessment of antral grinding of a model solid meal with echo-planar imaging. Am J Physiol Gastrointest Liver Physiol 2001, 280(5):G844-G849.
56. Marciani L., Young P., Wright J., Moore R., Coleman N., Gowland P.A., et al. Antral motility measurements by magnetic resonance imaging. Neurogastroenterol Motil 2001, 13(5):511-518.
57. Marciani L., Coleman N.S., Dunlop S.P., Singh G., Marsden C.A., Holmes G.K., et al. Gallbladder contraction, gastric emptying and antral motility: single visit assessment of upper GI function in untreated celiac disease using echo-planar MRI. J Magn Reson Imaging 2005, 22(5):634-638.
58. Cootes T, Edwards G, Taylor C. Active appearance models. Computer vision - ECCV'98. Berlin/Heidelberg: Springer; 1998. p. 484.
59. Schmid V.J., Whitcher B., Padhani A.R., Taylor N.J., Yang G. Bayesian methods for pharmacokinetic models in dynamic contrast-enhanced magnetic resonance imaging. IEEE Trans Med Imaging 2006, 25(12):1627-1636.
60. Ailiani A.C., Neuberger T., Brasseur J.G., Banco G., Wang Y., Smith N.B., et al. Quantitative analysis of peristaltic and segmental motion in vivo in the rat small intestine using dynamic MRI. Magn Reson Med 2009, 62(1):116-126.