Application of 13C stable isotope labeling liquid chromatography-multiple reaction monitoring-tandem mass spectrometry method for determining intact absorption of bioactive dipeptides in rats

Analytical Biochemistry

Volumn 414, Issue 1, 2011, Pages 109-116

  Nakashima, Eduardo M N ^a   Kudo, Akihiro ^a   Iwaihara, Yuri ^a   Tanaka, Mitsuru ^b   Matsumoto, Kiyoshi ^b   Matsui, Toshiro ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b SOJO UNIVERSITY   (Japan)

Author keywords

Absorption; Dipeptide; Mass spectrometry; Multiple reaction monitoring

Indexed keywords

ABSORPTION; BLOOD; ISOTOPES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PEPTIDES; POSITIVE IONS; RATS;

ANTIHYPERTENSIVE PEPTIDES; COEFFICIENT OF VARIATION; DI-PEPTIDES; HIGH REPRODUCIBILITY; MULTIPLE REACTION MONITORING; SPONTANEOUSLY HYPERTENSIVE RATS; STABLE-ISOTOPE LABELING; TANDEM MASS SPECTROMETRY;

ABSORPTION SPECTROSCOPY;

CARBON 13; DIPEPTIDE; FORMIC ACID; METHANOL; ANTIHYPERTENSIVE AGENT; CARBON;

ABSORPTION; ARTICLE; BLOOD SAMPLING; ELECTROSPRAY; FLOW RATE; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; ANIMAL; BLOOD; CHEMISTRY; MALE; METHODOLOGY; SPONTANEOUSLY HYPERTENSIVE RAT; SPRAGUE DAWLEY RAT; STATISTICAL MODEL; VALIDATION STUDY;

RATTUS;

ANIMALS; ANTIHYPERTENSIVE AGENTS; CARBON ISOTOPES; CHROMATOGRAPHY, LIQUID; DIPEPTIDES; ISOTOPE LABELING; LINEAR MODELS; MALE; RATS; RATS, INBRED SHR; RATS, SPRAGUE-DAWLEY; TANDEM MASS SPECTROMETRY;

EID: 79955697413     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.02.037     Document Type: Article

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