Radioembolization and systemic chemotherapy improves response and survival for unresectable colorectal liver metastases

Journal of Cancer Research and Clinical Oncology

Volumn 137, Issue 5, 2011, Pages 865-873

  Chua, Terence C ^a   Bester, Lourens ^a   Saxena, Akshat ^a   Morris, David L ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Colorectal cancer; Irinotecan; Liver metastases; Microspheres; Oxaliplatin; Radiotherapy; Yttrium 90

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL; YTTRIUM 90;

ABDOMINAL PAIN; ADULT; AGED; ARTICLE; BILIARY TRACT DISEASE; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER RADIOTHERAPY; CANCER SURVIVAL; CHEMOEMBOLIZATION; COLON CANCER; COLORECTAL CANCER; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; GALLBLADDER DISEASE; GASTRITIS; HUMAN; INOPERABLE CANCER; INTESTINE ULCER; LIVER DISEASE; LIVER DYSFUNCTION; LIVER METASTASIS; LIVER RESECTION; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; NAUSEA; OVERALL SURVIVAL; PNEUMONIA; PREDICTION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RECTUM CANCER; SEX DIFFERENCE; SURVIVAL TIME; TUMOR ABLATION; TUMOR LOCALIZATION; VOMITING;

ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; COMBINED MODALITY THERAPY; EMBOLIZATION, THERAPEUTIC; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; YTTRIUM RADIOISOTOPES;

EID: 79955687459     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-010-0948-y     Document Type: Article

References (34)

1. Adam R, Wicherts DA, de Haas RJ et al (2009) Patients with initially unresectable colorectal liver metastases: is there a possibility of cure? J Clin Oncol 27:1829-1835
2. Allen PJ, Nissan A, Picon AI et al (2005) Technical complications and durability of hepatic artery infusion pumps for unresectable colorectal liver metastases: an institutional experience of 544 consecutive cases. J Am Coll Surg 201:57-65 (Pubitemid 40840564)
3. Bengmark S, Hafstrom L (1969) The natural history of primary and secondary malignant tumours of the liver. Cancer 23:198-202
4. Bester L, Salem R (2007) Reduction of arteriohepatovenous shunting by temporary balloon occlusion in patients undergoing radioembolization. J Vasc Interv Radiol 18:1310-1314 (Pubitemid 47446272)
5. Campbell AM, Bailey IH, Burton MA (2001) Tumour dosimetry in human liver following hepatic 90Y microsphere therapy. Phys Med Biol 46:487-498 (Pubitemid 32148511)
6. Cassidy J, Clarke S, Diaz-Rubio E et al (2008) Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. J Clin Oncol 26:2006-2012
7. Colucci G, Gebbia V, Paoletti G et al (2005) Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale. J Clin Oncol 23:4866-4875 (Pubitemid 46223991)
8. Falcone A, Ricci S, Brunetti I et al (2007) Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest. J Clin Oncol 25:1670-1676 (Pubitemid 46797946)
9. Folprecht G, Gruenberger T, Bechstein WO et al (2010) Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial. Lancet Oncol 11:38-47
10. Fong Y, Kemeny N, Paty P et al (1996) Treatment of colorectal cancer: hepatic metastasis. Semin Surg Oncol 12:219-252 (Pubitemid 26255863)
11. Giantonio BJ, Catalano PJ, Meropol NJ et al (2007) Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 25:1539-1544 (Pubitemid 46733080)
12. Gray B, Van Hazel G, Hope M et al (2001) Randomised trial of SIR-Spheres® plus chemotherapy vs. chemotherapy alone for treating patients with liver metastases from primary large bowel cancer. Ann Oncol 12:1711-1720 (Pubitemid 34105661)
13. Hurwitz H, Fehrenbacher L, Novotny W et al (2004) Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer [see comment]. N Engl J Med 350:2335-2342 (Pubitemid 38702844)
14. Kemeny N, Fata F (1999) Arterial, portal or systemic chemotherapy for patients with hepatic metastasis of colorectal carcinoma. J Hepatobiliary Pancreat Surg 6:39-49
15. Khatri VP, Petrelli NJ, Belghiti J (2005) Extending the frontiers of surgical therapy for hepatic colorectal metastases: is there a limit? J Clin Oncol 23:8490-8499
16. Kim GP, Sargent DJ, Mahoney MR et al (2009) Phase III noninferiority trial comparing irinotecan with oxaliplatin, fluorouracil, and leucovorin in patients with advanced colorectal carcinoma previously treated with fluorouracil: N9841. J Clin Oncol 27:2848-2854
17. Kuebler JP (2009) Radioembolization of liver metastases in patients with colorectal cancer: a nonsurgical treatment with combined modality potential. J Clin Oncol 27:4041-4042
18. Mary FM, Robert JL, Saad MI et al (2009) Radioembolization of colorectal hepatic metastases using yttrium-90 microspheres. Cancer 115:1849-1858
19. Nicolay NH, Berry DP, Sharma RA (2009) Liver metastases from colorectal cancer: radioembolization with systemic therapy. Nat Rev Clin Oncol 6:687-697
20. Pawlik TM, Schulick RD, Choti MA (2008) Expanding criteria for resectability of colorectal liver metastases. Oncologist 13:51-64 (Pubitemid 351206696)
21. Porschen R, Arkenau H-T, Kubicka S et al (2007) Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in metastatic colorectal cancer: a final report of the AIO Colorectal Study Group. J Clin Oncol 25:4217-4223 (Pubitemid 47548561)
22. Salem R, Thurston KG (2006) Radioembolization with 90Yttrium microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies. Part 1: technical and methodologic considerations. J Vasc Interv Radiol 17:1251-1278 (Pubitemid 44259009)
23. Saltz LB, Cox JV, Blanke C et al (2000) Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group [see comment]. N Engl J Med 343:905-914
24. Saltz LB, Rosen LS, Marshall JL et al (2007) Phase II trial of sunitinib in patients with metastatic colorectal cancer after failure of standard therapy. J Clin Oncol 25:4793-4799 (Pubitemid 350086483)
25. Saltz LB, Clarke S, Diaz-Rubio E et al (2008) Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 26:2013-2019
26. Sobrero AF, Maurel J, Fehrenbacher L et al (2008) EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer. J Clin Oncol 26:2311-2319
27. Steele GJ, Ravikumar TS (1989) Resection of hepatic metastases from colorectal metastases: biologic perspectives. Ann Surg 210
28. Stubbs RS, O'Brien I, Correia MM (2006) Selective internal radiation therapy with 90Y microspheres for colorectal liver metastases: single-centre experience with 100 patients.ANZJ Surg 76:696-703
29. Therasse P, Arbuck SG, Eisenhauer EA et al (2000) New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92:205-216
30. Tomlinson JS, Jarnagin WR, DeMatteo RP et al (2007) Actual 10- year survival after resection of colorectal liver metastases defines cure. J Clin Oncol 25:4575-4580 (Pubitemid 350035315)
31. Vente MA, Wondergem M, van der Tweel I et al (2009) Yttrium-90 microsphere radioembolization for the treatment of liver malignancies: a structured meta-analysis. Eur Radiol 19:951-959
32. Viganò L, Ferrero A, Lo Tesoriere R et al (2008) Liver surgery for colorectal metastases: results after 10 years of follow-up. Long-term survivors, late recurrences, and prognostic role of morbidity. Ann Surg Oncol 15:2458-2464
33. Wagner JS, Adson MA, Van Heerden JA et al (1984) The natural history of hepatic metastases from colorectal cancer. A comparison with resective treatment. Ann Surg 199:502-508
34. Wood CB, Gillis CR, Blumgart LH (1976) A retrospective study of the natural history of patients with liver metastases from colorectal cancer. Clin Oncol 2:285-288