Defective interfering virus protects elderly mice from influenza

Virology Journal

Volumn 8, Issue , 2011, Pages

  Scott, Paul D ^a   Meng, Bo ^a   Marriott, Anthony C ^a   Easton, Andrew J ^a   Dimmock, Nigel J ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

defective interfering virus; elderly; geriatric; influenza; mice; treatment

Indexed keywords

VIRUS PROTEIN; VIRUS RNA; INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN; CLINICAL ASSESSMENT; CONTROLLED STUDY; DEFECTIVE VIRUS; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNITY; INFLUENZA; INFLUENZA VIRUS A; INOCULATION; MALE; MOUSE; NONHUMAN; PLASMID; VIRION; VIRUS PARTICLE; VIRUS REPLICATION; ANIMAL; BODY WEIGHT; C3H MOUSE; DISEASE MODEL; HOSPITALIZATION; IMMUNOLOGY; INFLUENZA VIRUS B; INNATE IMMUNITY; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; PATHOLOGY; RODENT DISEASE; VIROLOGY;

INFLUENZA A VIRUS; INFLUENZA B VIRUS; MUS; PARAMYXOVIRIDAE;

ANIMALS; BODY WEIGHT; DEFECTIVE VIRUSES; DISEASE MODELS, ANIMAL; FEMALE; IMMUNITY, INNATE; INFLUENZA A VIRUS; INFLUENZA B VIRUS; INTERFERONS; MALE; MICE; MICE, INBRED C3H; ORTHOMYXOVIRIDAE INFECTIONS; RODENT DISEASES; SEVERITY OF ILLNESS INDEX; VIRUS REPLICATION;

EID: 79955681204     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-8-212     Document Type: Article

References (45)

1. Respiratory viral infections in the elderly. JJ Treanor A Falsey, Antiviral Research 1999 44 79 102 10.1016/S0166-3542(99)00062-5 10669259
2. Immunity to influenza in the elderly. RG Webster, Vaccine 2000 18 1686 1689 10.1016/S0264-410X(99)00507-1 10689149 (Pubitemid 30109529)
3. Long-term care facilities: A cornucopia of viral pathogens. A Falsey G Dallal M Formica G Andolina D Hamer L Leka S Meydani, Journal of the American Geriatrics Society 2008 56 1281 1285 10.1111/j.1532-5415.2008.01775.x 18557966
4. TT Yoshikawa DC Norman, Infectious disease in the aging Towota, NJ: Humana Press 2000
5. Influenza-induced production of interferon- is defective in geriatric individuals. D Canaday N Amponsah L Jones D Tisch T Hornick L Ramachandra, Journal of Clinical Immunology 2010 30 373 383 10.1007/s10875-010-9374-9 20182777
6. Mucosal vaccination and immune responses in the elderly. K Fujihashi T Koga JR McGhee, Vaccine 2000 18 1675 1680 10.1016/S0264-410X(99)00505-8 10689147 (Pubitemid 30109527)
7. Immunosenescence and vaccination in nursing home residents. T Fulop G Pawelec S Castle M Loeb, Clinical Infectious Diseases 2009 48 443 448 10.1086/596475 19140756
8. In vivo T cell activation, in vitro defective IL-2 secretion, and response to influenza vaccination in elderly women. YP Huang JC Pechere M Michel L Gauthey M Loreto JA Curran JP Michel, Journal of Immunology 1992 148 715 722
9. Pandemic influenza H1N1 2009, innate immunity, and the impact of immunosenescence on influenza vaccine. SR Joshi AC Shaw VJ Quagliarello, Yale Journal of Biology and Medicine 2009 82 143 151 20027279
10. Age-associated changes within CD4+ T cells. RD Kovaiou B Grubeck-Loebenstein, Immunology Letters 2006 107 8 14 10.1016/j.imlet.2006.07. 006 16949678 (Pubitemid 44332549)
11. Diminished influenza A virus-specific MHC class I-restricted cytotoxic T lymphocyte activity among elderly persons. IN Mbawuike AR Lange RB Couch, Viral Immunology 1993 6 55 64 10.1089/vim.1993.6.55 8476508 (Pubitemid 23108508)
12. Dendritic cells in a mature age. C Reis e Sousa, Nature Reviews in Immunology 2007 6 476 483
13. Reduction in functional antibody activity against Streptococcus pneumoniae in vaccinated elderly individuals highly correlates with decreased IgG antibody avidity. S Romero-Steiner DM Musher MS Cetron LB Pais JE Groover AE Fiore BD Plikaytis GM Carlone, Clinical and Infectious Disease 1999 29 281 288 10.1086/520200 (Pubitemid 29380185)
14. Age-dependent alterations of the T cell repertoire and functional diversity of T cells of the aged. AN Vallejo, Immunological Research 2007 36 221 228 (Pubitemid 46398598)
15. Prevention and treatment of influenza in high-risk groups: children, pregnant women, immunocompromised hosts, and nursing home residents. RJ Whitley AS Monto, Journal of Infectious Diseases 2006 194 S2 133 S138 10.1086/507548 17163386
16. Influenza and respiratory syncytial virus in the elderly. A Elliot D Fleming, Expert Review of Vaccines 2008 7 249 258 10.1586/14760584.7.2.249 18324893 (Pubitemid 351357959)
17. Influenza. NJ Cox K Subbarao, The Lancet 1999 354 1277 1282 10.1016/S0140-6736(99)01241-6 (Pubitemid 29469365)
18. Structural basis of immune recognition of influenza virus hemagglutinin. IA Wilson NJ Cox, Annual Review of Immunology 1990 8 737 771 10.1146/annurev.iy.08.040190.003513 2188678 (Pubitemid 20135645)
19. The efficacy of influenza vaccine in elderly persons. A meta-analysis and review of the literature. PA Gross A Hermogenes HS Sacks J Lau RA Levandowski, Annals of Internal Medicine 1995 123 518 527 7661497
20. Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review. T Jefferson D Rivetti M Rudin C Di Pietrantonj V Demicheli, Lancet 2005 366 1165 1174 10.1016/S0140-6736(05)67339-4 16198765 (Pubitemid 41393594)
21. Antibody response to influenza vaccination in the elderly: a quantitative review. K Goodwin C Viboud L Simonsen, Vaccine 2006 24 1159 1169 10.1016/j.vaccine.2005.08.105 16213065 (Pubitemid 43202262)
22. Vaccines for preventing influenza in the elderly. T Jefferson C Di Pietrantonj LA Al-Ansary E Ferroni S Thorning RE Thomas, Cochrane Database of Systematic Reviews 2010 2 2 D004876
23. Neuraminidase inhibitors for preventing and treating influenza in healthy adults. T Jefferson M Jones P Doshi C Del Mar L Dooley R Foxlee, Cochrane Database of Systematic Reviews, Issue 2, article number CD001265 2010
24. Influenza (H5N1) with decreased oseltamivir sensitivity, Indonesia. JL McKimm-Breschkin PW Selleck TB Usman MA Johnson, Emerging Infectious Diseases 2007 13 1354 1357 18252107 (Pubitemid 47510297)
25. Implications of antiviral resistance of influenza viruses. A Monto, Clinical Infectious Diseases 2009 48 397 399 10.1086/596312 19586376
26. Influenza virus susceptibility and resistance to oseltamivir. FY Aoki G Boivin N Roberts, Antiviral Therapy 2007 12 603 616 17944268 (Pubitemid 47235503)
27. Defective viral genomes. JJ Holland, Virology New York: Raven Press, Fields BN, Knipe DM, 2 1990 1 151 165
28. Generation and replication of defective viral genomes. JJ Holland, Virology New York: Raven Press, Fields BN, Knipe DM, 2 1990 77 99
29. Defective viral particles and viral disease processes. AS Huang D Baltimore, Nature (London) 1970 226 325 327 10.1038/226325a0
30. Structure of defective-interfering RNAs of influenza virus and their role in interference. DP Nayak TM Chambers RM Akkina, The Influenza Viruses New York: Plenum Press, Krug RM, 1989 269 317
31. Origin and replication of defective interfering particles. J Perrault, Current Topics in Microbiology and Immunology 1981 93 151 207 7026180
32. Incomplete forms of influenza virus. P von Magnus, Advances in Virus Research 1954 21 59 79
33. Defective-interfering (DI) RNAs of influenza viruses: origin, structure, expression and interference. DP Nayak TM Chambers RK Akkina, Current Topics in Microbiology and Immunology 1985 114 103 151 3888540
34. Does the higher order of the influenza virus ribonucleoprotein guide sequence rearrangements in influenza viral RNA. PA Jennings JT Finch G Winter JS Robertson, Cell 1983 34 619 627 10.1016/0092-8674(83)90394-X 6616623
35. Heterologous protection against a lethal human H1N1 influenza virus infection of mice by a H3N8 equine defective interfering virus: comparison of defective RNA sequences isolated from the DI inoculum and mouse lung. SD Duhaut NJ Dimmock, Virology 1998 248 241 253 10.1006/viro.1998.9267 9721233 (Pubitemid 28417711)
36. Influenza virus protecting RNA: an effective prophylactic and therapeutic antiviral. NJ Dimmock EW Rainsford PD Scott AC Marriott, Journal of Virology 2008 82 8570 8578 10.1128/JVI.00743-08 18579602
37. Defective interfering viruses and their potential as antiviral agents. AC Marriott NJ Dimmock, Reviews in Medical Virology 2010 20 51 62 10.1002/rmv.641 20041441
38. Impaired immune responses in the lungs of aged mice following influenza infection. FR Toapanta TM Ross, Respiratory Research 2009 10 112 10.1186/1465-9921-10-112 19922665
39. Immunization by influenza virus-like particles protects aged mice against lethal influenza virus challenge. ZY Wen L Ye YL Gao L Pan K Dong ZG Bu RW Compans CL Yang, Antiviral Research 2009 84 215 224 10.1016/j.antiviral.2009.09. 005 19772876
40. The senescence-accelerated mouse shows aging-related defects in cellular but not humoral imunity against influenza virus. L Dong I Mori MJ Hossain Y Kimura, Journal of Infectious Diseases 2000 182 391 396 10.1086/315727 10915067 (Pubitemid 30651035)
41. An immunostimulatory oligodeooxynucleotide containing a cytidine-guanosine motif protects senescence-accelerated mice from lethal influenza virus by augmenting the T helper type 1 response. L Dong I Mori MJ Hossain B Liu Y Kimura, Journal of General Virology 2003 84 1623 1628 10.1099/vir.0.19029-0 12771433 (Pubitemid 36675534)
42. The immune response of aged mice to influenza: diminished T-cell proliferation, interleukin 2 production and cytotoxicity. RB Effros RL Walford, Cellular Immunolology 1983 81 298 305 10.1016/0008-8749(83)90237-X (Pubitemid 13017143)
43. Age-associated decrease in virus-specific CD8+ T lymphocytes during primary influenza infection. JL Po EM Gardner F Anaraki PD Katsikis DM Murasko, Mechanisms of Ageing and Development 2002 123 1167 1181 10.1016/S0047-6374(02) 00010-6 12044966 (Pubitemid 34603100)
44. Rectification of age-associated deficiency in cytotoxic T cell response to influenza A virus by immunization with immune complexes. B Zheng Y Zhang H He E Marinova K Switzer D Wansley I Mbawuike S Han, Journal of Immunology 2007 179 6153 6159
45. A novel broad-spectrum treatment for respiratory virus infections: influenza-based defective interfering virus provides protection against pneumovirus infection in vivo. AJ Easton PD Scott NL Edworthy B Meng AC Marriott NJ Dimmock, Vaccine 2011 29 2777 2784 10.1016/j.vaccine.2011.01.102 21320545