Base-catalyzed synthesis of bicyclic 4-aminopyrimidines from the reaction of dinitriles with mononitriles

Tetrahedron

Volumn 67, Issue 21, 2011, Pages 3839-3845

  Chercheja, Serghei ^a   Simpson, Juliet K ^b   Lam, Hon Wai ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

4 Aminopyrimidine; Base catalysis; Cyclization; Dinitrile; Nitrile

Indexed keywords

ALIPHATIC COMPOUND; AMINE; AROMATIC COMPOUND; BICYCLIC 4 AMINOPYRIMIDINE DERIVATIVE; NITRILE; POTASSIUM; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANNULATION REACTION; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; CYCLIZATION; PRIORITY JOURNAL; SYNTHESIS; THORPE ZIEGLER REACTION;

EID: 79955670847     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2011.03.098     Document Type: Article

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