MRI of Transplanted Neural Stem Cells

Methods in Molecular Biology

Volumn 711, Issue , 2011, Pages 435-449

  Berman, Stacey M Cromer ^a   Walczak, Piotr ^a   Bulte, Jeff W M ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cell tracking; cell transplantation; Magnetic resonance imaging; MR contrast agent; stem cell; superparamagnetic iron oxide

Indexed keywords

FERRIC ION; FERRIC OXIDE;

ANIMAL; ARTICLE; BRAIN; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; IMMUNOHISTOCHEMISTRY; MAGNETISM; METABOLISM; METHODOLOGY; MOUSE; NEURAL STEM CELL; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; STAINING; STATISTICS; TRANSPLANTATION;

ANIMALS; BRAIN; CELL PROLIFERATION; CELLS, CULTURED; FERRIC COMPOUNDS; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MAGNETICS; MICE; NEURAL STEM CELLS; STAINING AND LABELING; STATISTICS AS TOPIC;

EID: 79955669983     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-61737-992-5_22     Document Type: Chapter

References (24)

1. Wang, L., Martin, D. R., Baker, H. J. et al. Neural progenitor cell transplantation and imaging in a large animal model. Neurosci Res 2007;59:327–340.
2. Ben-Hur, T., Idelson, M., Khaner, H. et al. Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in parkinsonian rats. Stem Cells 2004;22:1246–1255.
3. Yu, J., Vodyanik, M. A., Smuga-Otto, K. et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318:1917–1920.
4. Bulte, J. W. In vivo MRI cell tracking: Clinical studies. AJR Am J Roentgenol 2009;193:314–325.
5. Walczak, P., Bulte, J. W. The role of noninvasive cellular imaging in developing cell-based therapies for neurodegenerative disorders. Neurodegener Dis 2007;4:306–313.
6. Ben-Hur, T., van Heeswijk, R. B., Einstein, O. et al. Serial in vivo MR tracking of magnetically labeled neural spheres transplanted in chronic EAE mice. Magn Reson Med 2007;57:164–171.
7. Connor, D. M., Benveniste, H., Dilmanian, F. A., Kritzer, M. F., Miller, L. M., Zhong, Z. Computed tomography of amyloid plaques in a mouse model of Alzheimer’s disease using diffraction enhanced imaging. Neuroimage 2009;46:908–914.
8. Adonai, N., Nguyen, K. N., Walsh, J. et al. Ex vivo cell labeling with 64cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for imag- ing cell trafficking in mice with positron-emission tomography. Proc Natl Acad Sci USA 2002;99:3030–3035.
9. Acton, P. D., Zhou, R. Imaging reporter genes for cell tracking with PET and SPECT. Q J Nucl Med Mol Imaging 2005;49: 349–360.
10. Chaudhari, A. J., Darvas, F., Bading, J. R. et al. Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging. Phys Med Biol 2005;50: 5421–5441.
11. Judenhofer, M. S., Wehrl, H. F., Newport, D. F. et al. Simultaneous PET-MRI: A new approach for functional and morphological imaging. Nat Med 2008;14:459–465.
12. Modo, M., Hoehn, M., Bulte, J. W. Cellular MR imaging. Mol Imaging 2005;4:143–164.
13. Walczak, P., Kedziorek, D. A., Gilad, A. A., Barnett, B. P., Bulte, J. W. Applicability and limitations of MR tracking of neural stem cells with asymmetric cell division and rapid turnover: The case of the shiverer dysmyelinated mouse brain. Magn Reson Med 2007;58:261–269.
14. Gilad, A. A., McMahon, M. T., Walczak, P. et al. Artificial reporter gene providing MRI contrast based on proton exchange. Nat Biotechnol 2007;25:217–219.
15. Bulte, J. W., Kraitchman, D. L. Iron oxide MR contrast agents for molecular and cellular imaging. Nmr Biomed 2004;17:484–499.
16. Frank, J. A., Miller, B. R., Arbab, A. S. et al. Clinically applicable labeling of mammalian and stem cells by combining superparamagnetic iron oxides and transfection agents. Radiology 2003;228:480–487.
17. Bulte, J. W., Arbab, A. S., Douglas, T., Frank, J. A. Preparation of magnetically labeled cells for cell tracking by magnetic resonance imaging. Methods Enzymol 2004;386: 275–299.
18. Walczak, P., Kedziorek, D. A., Gilad, A. A., Lin, S., Bulte, J. W. Instant MR labeling of stem cells using magnetoelectroporation. Magn Reson Med 2005;54:769–774.
19. Cohen, M. E., Muja, N., Fainstein, N., Bulte, J. W., Ben-Hur, T. Conserved fate and function of ferumoxides-labeled neural precursor cells in vitro and in vivo. J Neurosci Res 2010;88:936–944.
20. Magnitsky, S., Watson, D. J., Walton, R. M. et al. In vivo and ex vivo MRI detection of localized and disseminated neural stem cell grafts in the mouse brain. Neuroimage 2005;26:744–754.
21. Snyder, E. Y., Deitcher, D. L., Walsh, C., Arnold-Aldea, S., Hartwieg, E. A., Cepko, C. L. Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell 1992;68:33–51.
22. Alric, C., Taleb, J., Le Duc, G. et al. Gadolinium chelate coated gold nanoparticles as contrast agents for both X-ray computed tomography and magnetic resonance imaging. J Am Chem Soc 2008;130:5908–5915.
23. Arbab, A. S., Yocum, G. T., Kalish, H. et al. Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI. Blood 2004;104: 1217–1223.
24. Paxinos, G., Franklin, K. B. J. The Mouse Brain – In Stereotactic Coordinates. San Diego, CA: Academic Press; 2001.