Identification of BCP-20 (FBXO39) as a cancer/testis antigen from colon cancer patients by SEREX

Biochemical and Biophysical Research Communications

Volumn 408, Issue 2, 2011, Pages 195-201

  Song, Myung Ha ^a   Ha, Jong Cheon ^b   Lee, Sang Mok ^b   Park, Yeong Min ^a   Lee, Sang Yull ^a  

^a Pusan National University School of Medicine   (South Korea)

^b Biocurepharm Co Ltd   (South Korea)

Author keywords

Colon cancer; CT antigen; SEREX; Tumor antigen

Indexed keywords

BCP 20 ANTIGEN; CANCER TESTIS ANTIGEN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ANTIGEN EXPRESSION; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER DIAGNOSIS; CANCER IMMUNOTHERAPY; COLON CANCER; CONTROLLED STUDY; DNA LIBRARY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; KIDNEY CANCER; LIVER CANCER; LUNG CANCER; MOLECULAR CLONING; OVARY CANCER; PRIORITY JOURNAL; PROTEIN PURIFICATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOMA; SERODIAGNOSIS; SEROLOGICAL ANALYSIS OF RECOMBINANT CDNA EXPRESSION LIBRARIES; STOMACH CANCER; THYROID CANCER;

AGED; AGED, 80 AND OVER; ANTIGENS, NEOPLASM; COLONIC NEOPLASMS; DNA, RECOMBINANT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE LIBRARY; HUMANS; IMMUNOTHERAPY; MALE; MIDDLE AGED; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; SEROLOGIC TESTS; TESTIS;

EID: 79955666401     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.077     Document Type: Article

References (35)

1. Desmetz C., Maudelonde T., Mange A., Solassol J. Identifying autoantibody signatures in cancer: a promising challenge. Expert. Rev. Proteomics 2009, 6:377-386.
2. Wang K., Xu X., Nie Y., Dai L., Wang P., Zhang J. Identification of tumor-associated antigens by using SEREX in hepatocellular carcinoma. Cancer Lett. 2009, 281:144-150.
3. Okada H., Attanucci J., Giezeman-Smits K.M., Brissette-Storkus C., Fellows W.K., Gambotto A., Pollack L.F., Pogue-Geile K., Lotze M.T., Bozik M.E., Chambers W.H. Immunization with an antigen identified by cytokine tumor vaccine-assisted SEREX (CAS) suppressed growth of the rat 9L glioma in vivo. Cancer Res. 2001, 61:2625-2631.
4. Geng L., Deepak P.A., Aija L., Fuming C., Amanda M., Robert C.R., Stephanie E.B.M. Identification of metastasis associated antigen 1 (MTA1) by serological screening of prostate cancer cDNA libraries. Open Biochem. J. 2008, 2:100-107.
5. Chatterjee M., Mohapatra S., Ionan A., Bawa G., Ali-Fehmi R., Wang X., Nowak J., Ye B., Nahhas F.A., Lu K., Witkin S.S., Fishman D., Munkarah A., Morris R., Levin N.K., Shirley N.N., Tromp G., Abrams J., Draghici S., Tainsky M.A. Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays. Cancer Res. 2006, 66:1181-1190.
6. Liggins A.P., Guinn B.A., Banham A.H. Identification of lymphoma-associated antigens using SEREX. Methods Mol. Med. 2005, 115:109-128.
7. Chen G., Zhang W., Cao X., Li F., Liu X., Yao L. Serological identification of immunogenic antigens in acute monocytic leukemia. Leuk. Res. 2005, 29:503-509.
8. Sahin U., Tureci O., Schmitt H., Cochlovius B., Johannes T., Schmits R., Stenner F., Luo G., Schobert I., Pfreundschuh M. Human neoplasms elicit multiple specific immune responses in the autologous host. Proc. Natl. Acad. Sci. USA 1995, 92:11810-11813.
9. Chen Y.T., Scanlan M.J., Sahin U., Tureci O., Gure A.O., Tsang S., Williamson B., Stockert E., Pfreundschuh M., Old L.J. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. Proc. Natl. Acad. Sci. USA 1997, 94:1914-1918.
10. Scanlan M.J., Gordan J.D., Williamson B., Stockert E., Bander N.H., Jongeneel V., Gure A.O., Jager D., Jager E., Knuth A., Chen Y.T., Old L.J. Antigens recognized by autologous antibody in patients with renal-cell carcinoma. Int. J. Cancer 1999, 83:456-464.
11. Scanlan M.J., Gout I., Gordon C.M., Williamson B., Stockert E., Gure A.O., Jager D., Chen Y.T., Mackay A., O'Hare M.J., Old L.J. Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression. Cancer Immun. 2001, 1:4.
12. Jager D., Stockert E., Gure A.O., Scanlan M.J., Karbach J., Jager E., Knuth A., Old L.J., Chen Y.T. Identification of a tissue-specific putative transcription factor in breast tissue by serological screening of a breast cancer library. Cancer Res. 2001, 61:2055-2061.
13. Scanlan M.J., Gure A.O., Jungbluth A.A., Old L.J., Chen Y.T. Cancer/testis antigens: an expanding family of targets for cancer immunotherapy. Immunol. Rev. 2002, 188:22-32.
14. Liang Z., Sun Z.Y., Yuan Y.H., Han Y., Wang Y., Gu J., Zhang L.J. The expression of 11 cancer/testis (CT) antigen genes in esophageal carcinoma. Zhonghua Zhong Liu Za Zhi 2005, 27:534-537.
15. Lu H., Goodell V., Disis M.L. Humoral immunity directed against tumor-associated antigens as potential biomarkers for the early diagnosis of cancer. J. Proteome Res. 2008, 7:1388-1394.
16. Simpson A.J., Caballero O.L., Jungbluth A., Chen Y.T., Old L.J. Cancer/testis antigens, gametogenesis and cancer. Nat. Rev. Cancer 2005, 5:615-625.
17. Scanlan M.J., Simpson A.J., Old L.J. The cancer/testis genes: review, standardization, and commentary. Cancer Immun 2004, 4:1.
18. Scanlan M.J., Chen Y.T., Williamson B., Gure A.O., Stockert E., Gordan J.D., Tureci O., Sahin U., Pfreundschuh M., Old L.J. Characterization of human colon cancer antigens recognized by autologous antibodies. Int. J. Cancer 1998, 76:652-658.
19. Line A., Slucka Z., Stengrevics A., Silina K., Li G., Rees R.C. Characterisation of tumour-associated antigens in colon cancer. Cancer Immunol. Immunother. 2002, 51:574-582.
20. Ishikawa T., Fujita T., Suzuki Y., Okabe S., Yuasa Y., Iwai T., Kawakami Y. Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability. Cancer Res. 2003, 63:5564-5572.
21. Klade C.S., Voss T., Krystek E., Ahorn H., Zatloukal K., Pummer K., Adolf G.R. Identification of tumor antigens in renal cell carcinoma by serological proteome analysis. Proteomics 2001, 1:890-898.
22. Dong X.Y., Su Y.R., Qian X.P., Yang X.A., Pang X.W., Wu H.Y., Chen W.F. Identification of two novel CT antigens and their capacity to elicit antibody response in hepatocellular carcinoma patients. Br. J. Cancer 2003, 89:291-297.
23. Biragyn A., Schiavo R., Olkhanud P., Sumitomo K., King A., McCain M., Indig F.E., Almanzar G., Baatar D. Tumor-associated embryonic antigen-expressing vaccines that target CCR6 elicit potent CD8+ T cell-mediated protective and therapeutic antitumor immunity. J. Immunol. 2007, 179:1381-1388.
24. Wang Y., Han K.J., Pang X.W., Vaughan H.A., Qu W., Dong X.Y., Peng J.R., Zhao H.T., Rui J.A., Leng X.S., Cebon J., Burgess A.W., Chen W.F. Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies. J. Immunol. 2002, 169:1102-1109.
25. Crew A.J., Clark J., Fisher C., Gill S., Grimer R., Chand A., Shipley J., Gusterson B.A., Cooper C.S. Fusion of SYT to two genes, SSX1 and SSX2 Encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma. Embo J. 1995, 14:2333-2340.
26. Ehlken H., Schadendorf D., Eichmuller S. Humoral immune response against melanoma antigens induced by vaccination with cytokine gene-modified autologous tumor cells. Int. J. Cancer. 2004, 108:307-313.
27. Karbach J., Pauligk C., Bender A., Gnjatic S., Franzmann K., Wahle C., Jager D., Knuth A., Old L.J., Jager E. Identification of new NY-ESO-1 epitopes recognized by CD4+ T cells and presented by HLA-DQ B1 03011. Int. J. Cancer 2006, 118:668-674.
28. Chen Y.T., Gure A.O., Tsang S., Stockert E., Jager E., Knuth A., Old L.J. Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library. Proc. Natl. Acad. Sci. USA 1998, 95:6919-6923.
29. Cenciarelli C., Chiaur D.S., Guardavaccaro D., Parks W., Vidal M., Pagano M. Identification of a family of human F-box proteins. Curr. Biol. 1999, 9:1177-1179.
30. Jin J., Cardozo T., Lovering R.C., Elledge S.J., Pagano M., Harper J.W. Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev. 2004, 18:2573-2580.
31. Sun L., Shi L., Li W., Yu W., Liang J., Zhang H., Yang X., Wang Y., Li R., Yao X., Yi X., Shang Y. JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation. Proc. Natl. Acad. Sci. USA 2009, 106:10195-10200.
32. Trichet V., Ruault M., Roizes G., De Sario A. Characterization of the human tubulin tyrosine ligase-like 1 gene (TTLL1) mapping to 22q13.1. Gene 2000, 257:109-117.
33. Lafanechere L., Courtay-Cahen C., Kawakami T., Jacrot M., Rudiger M., Wehland J., Job D., Margolis R.L. Suppression of tubulin tyrosine ligase during tumor growth. J. Cell Sci. 1998, 111(Pt 2):171-181.
34. Olesen C., Larsen N.J., Byskov A.G., Harboe T.L., Tommerup N. Human FATE is a novel X-linked gene expressed in fetal and adult testis. Mol. Cell Endocrinol. 2001, 184:25-32.
35. Sargent C.A., Young C., Marsh S., Ferguson-Smith M.A., Affara N.A. The glycerol kinase gene family: structure of the Xp gene and related intronless retroposons. Hum. Mol. Genet. 1994, 3:1317-1324.