Biopharmaceutical applications of nanogold

Saudi Pharmaceutical Journal

Volumn 18, Issue 4, 2010, Pages 179-193

  Alanazi, Fars K ^a   Radwan, Awwad A ^a,b   Alsarra, Ibrahim A ^c  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b Assiut University   (Egypt)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Drug delivery; Gold; Gold catalysis; Nanogold; Nanotechnology

Indexed keywords

3 AMINOINDOLIZINE; ALKENE DERIVATIVE; ALKYNE DERIVATIVE; ALPHA FETOPROTEIN; ARYL GROUP; BETA LAPACHONE; BIOLOGICAL MARKER; CA 125 ANTIGEN; CA 19-9 ANTIGEN; CARBON; CARCINOEMBRYONIC ANTIGEN; CETUXIMAB; CHROMAN DERIVATIVE; DNA; EPOXIDE; FUNCTIONAL GROUP; GEMCITABINE; GOLD NANOPARTICLE; HEPATITIS B SURFACE ANTIGEN; IMINE; INDOLIZINE DERIVATIVE; METHANOL; METHOTREXATE; NITRIC OXIDE; OXYGEN; PLASMID DNA; PROSTATE SPECIFIC ANTIGEN; SINGLET OXYGEN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ABSORPTION; ADDITION REACTION; ARYLATION; BIOSENSOR; BIOSYNTHESIS; CATALYSIS; CHEMICAL BOND; DRUG DELIVERY SYSTEM; DRUG TARGETING; FRIEDEL CRAFTS REACTION; HUMAN; HYDROARYLATION; IMMUNOHISTOCHEMISTRY; IMMUNOSENSOR; LIGHT SCATTERING; NANOENCAPSULATION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OXIDATION; PHOTODYNAMIC THERAPY; PHYSICAL CHEMISTRY; REVIEW; SUBSTITUTION REACTION; SURFACE PLASMON RESONANCE; SYNTHESIS;

EID: 79955665096     PISSN: 13190164     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsps.2010.07.002     Document Type: Review

References (110)

1. Ahmad A., Senapati S., Khan M.I., Kumar R., Ramani R., Srinivas V., Sastry M. Intracellular synthesis of gold nanoparticles by a novel alkalotolerant actinomycete, Rhodococcus species. Nanotechnology 2003, 14:824-828.
2. Ahmad A., Mukherjee P., Senapati S., Mandal D., Khan M.I., Kumar R., Sastry M. Extracellular biosynthesis of silver nanoparticles using the fungus Fusarium oxysporum. Colloids Surf. 2003, B28:313-318.
3. Angelatos A.S., Radt B., Caruso F. Light-responsive polyelectrolyte/gold nanoparticle microcapsules. J. Phys. Chem. B 2005, 109:3071-3076.
4. Anshup A., Venkataraman J.S., Chandramouli S., Rajeev K.R., Suma P., Santhosh K.T.R., Omkumar R.V., Annie J., Pradeep T. Growth of gold nanoparticles in human cells. Langmuir 2005, 21:11562-11567.
5. Arcadi A., Di Giuseppe S. Recent applications of gold catalysis in organic synthesis. Curr. Org. Chem. 2004, 8:795-812.
6. Arcadi A., Bianchi G., Chiarini M., D'Anniballe G., Marinelli F. Gold-catalyzed conjugate addition type reaction of indoles with α,β-enones. Synlett 2004, 944-950.
7. Balme G., Bossharth E., Monteiro N. Pd-assisted multicomponent synthesis of heterocycles. Eur. J. Org. Chem. 2003, 4101-4102.
8. Bhumkar D.R., Joshi H.M., Sastry M., Pokharkar V.B. Chitosan reduced gold nanoparticles as novel carriers for transmucosal delivery of insulin. Pharm. Res. 2007, 24:1415-1426.
9. Bonoiu A.C., Mahajan S.D., Ding H., Roy I., Yong K.T., Kumar R., Hu R., Bergey E.J., Schwartz S.A., Prasad P.N. Nanotechnology approach for drug addiction therapy: gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neurons. Proc. Natl. Acad. Sci. USA 2009, 106:5546-5550.
10. Brown K.R., Natan M.J. Hydroxylamine seeding of colloidal Au nanoparticles in solution and on surfaces. Langmuir 1998, 14:726-728.
11. Chen W., Cai W.P., Liang C.H., Zhang L.D. Synthesis of gold nanoparticles dispersed within pores of mesoporous silica induced by ultrasonic irradiation and its characterization. Mater. Res. Bull. 2001, 36:335-342.
12. Chen Y.H., Tsai C.Y., Huang P.Y., Chang M.Y., Cheng P.C., Chou C.H., Chen D.H., Wang C.R., Shiau A.L., Wu C.L. Methotrexate conjugated to gold nanoparticles inhibits tumor growth in a syngeneic lung tumor model. Mol. Pharm. 2007, 4:713-722.
13. Chiang C.L. Controlled growth of gold nanoparticles in aerosol-OT/sorbitan monooleate/isooctane mixed reverse micelles. Colloid Interface Sci. 2000, 230:60-66.
14. Connor E.E., Mwamuka J., Gole A., Murphy C.J., Wyatt M.D. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 2005, 1:325-327.
15. Dawson A., Kamat P.V. Complexation of gold nanoparticles with radiolytically generated thiocyanate radicals (SCN)2-. J. Phys. Chem. B 2000, 104:11842-11846.
16. de Graaf P.W.J., Boersma J., van der Kerk G.J.M. Preparation and properties of arylgold compounds. Scope and limitations of the auration reaction. J. Organomet. Chem. 1976, 105:399-406.
17. Dianping T., Ruo Y., Yaqin C., Linyan Z., Xia Z., Yan L., Jianyuan D. Preparation and application on a kind of immobilization method of anti-diphtheria for potentiometric immunosensor modified colloidal Au and polyvinyl butyral as matrixes. Sens. Actuators B 2005, 104:199-206.
18. Engin K., Leeper D.B., Cater J.R., Thistlethwaite A.J., Tupchong L., Mcfarlane J.D. Extracellular pH distribution in human tumors. Int. J. Hypertherm. 1995, 11:211-216.
19. Esumi K., Hosoya T., Suzuki A. Preparation of hydrophobically modified poly(amidoamine) dendrimer-encapsulated gold nanoparticles. J. Colloid Interface Sci. 2000, 229:303-306.
20. Frens G. Controlled nucleation for the regulation of the particle size in monodisperse gold suspensions. Nat. Phys. Sci. 1973, 241:20-22.
21. Fukuda Y., Utimoto K. Effective transformation of unactivated alkynes into ketones or acetals with a gold(III) catalyst. J. Org. Chem. 1991, 56:3729-3731.
22. Georgy M., Boucard V., Campagne J.-M.J. Gold(III)-catalyzed nucleophilic substitution of propargylic alcohols. J. Am. Chem. Soc. 2005, 127:14180-14181.
23. Gustav M., Mie G. Beiträge zur Optik trüber Medien, speziell kolloidaler Metallösungen. Ann. Phys. Vierte Folge 1908, 25:377.
24. Haifeng Z., Cheng T., Suping Z., Junbai L. One step synthesis and phase transition of phospholipid-modified Au particles into toluene. Colloids Surf. A: Physicochem. Eng. Aspects 2005, 257-258:411-414.
25. Hashmi A.S.K., Schwarz L., Choi J.H., Frost T.M. A new gold-catalyzed C-C bond formation. Angew. Chem. Int. Ed. 2000, 39:2285-2288.
26. Hayashi T., Sawamura M., Ito Y. Asymmetric-synthesis catalyzed by chiral ferrocenylphosphine-transition metal-complexes; gold(I)-catalyzed asymmetric aldol reaction of isocyanoacetate. Tetrahedron 1992, 48:1999-2012.
27. Henglein A., Meisel D. Radiolytic control of the size of colloidal gold nanoparticles. Langmuir 1998, 14:7392-7396.
28. Hone D.C., Walker P.I., Evans-Gowing R., FitzGerald S., Beeby A., Chambrier I., Cook M.J., Russell D.A. Generation of cytotoxic singlet oxygen via phthalocyanine stabilized gold nanoparticles: a potential delivery vehicle for photodynamic therapy. Langmuir 2002, 18:2985-2987.
29. Hong R., Han G., Fernandez J.M., Kim B.J., Forbes N.S., Rotello V.M. Glutathione-mediated delivery and release using monolayer protected nanoparticle carriers. J. Am. Chem. Soc. 2006, 128:1078-1079.
30. Hu J., Chen L., Zhu K., Suchopar A., Richards R. Aerobic oxidation of alcohols catalyzed by gold nano-particles confined in the walls of mesoporous silica. Catal. Today 2007, 122:277-283.
31. Huang H., Yang X. Synthesis of polysaccharide-stabilized gold and silver nanoparticles: a green method. Carbohydr. Res. 2004, 339:2627-2631.
32. Huang X., Qian W., El-Sayed I.H., El-Sayed M.A. The potential use of the enhanced nonlinear properties of gold nanospheres in photothermal cancer therapy. Laser Surg. Med. 2007, 39:747-753.
33. Hutchings G.J. New direction in gold catalysis. Gold Bull. 2004, 37:3-11.
34. Itahara T., Kawasaki K., Ouseto F. Alkenylation of 1-benzenesulfonylindole with olefins bearing electron-withdrawing substituents. Synthesis 1984, 236-237.
35. Ivan H.E., Xiaohua H., Mostafa A.E. Surface plasmon resonance scattering and absorption of anti-EGFR antibody conjugated gold nanoparticles in cancer diagnostics: applications in oral cancer. Nano Lett. 2005, 5:829-834.
36. Jana N.R., Gearheart L., Murphy C.J. Evidence for seed-mediated nucleation in the formation of gold nanoparticles from gold salts. Chem. Mater. 2001, 13:2313-2322.
37. Jones C.J., Taube D., Ziatdinov V.R., Periana R.A., Nielsen R.J., Oxgaard J., Goddard W.A. Selective oxidation of methane to methanol catalyzed, with C-H activation, by homogeneous, cationic gold. Angew. Chem. Int. Ed. 2004, 43:4626-4629.
38. Kawano T., Yamagata M., Takahashi H., Niidome Y., Yamada S., Katayama Y., Niidome T. Stabilizing of plasmid DNA in vivo by PEG-modified cationic gold nanoparticles and the gene expression assisted with electrical pulses. J. Controlled Release 2006, 111:382-389.
39. Kerman K., Morita Y., Takamura Y., Ozsoz M., Tamiya E. Modification of Escherichia coli single-stranded DNA binding protein with gold nanoparticles for electrochemical detection of DNA hybridization. Anal. Chim. Acta 2004, 510:169-174.
40. Kharasch M.S., Isbell H.S.J. J. Am. Chem. Soc. 1931, 53:3053-3059.
41. Ko S.H., Choi Y., Hwang D.J., Grigoropoulos C.P., Chung J., Poulikakos D. Nanosecond laser ablation of gold nanoparticle films. Appl. Phys. Lett. 2006, 89:141126-1-141126-3.
42. Lee K.M., Park S.T., Lee D.J. Nanogold synthesis by inert gas condensation for immuno-chemistry probes. J. Alloys Compd. 2005, 390:297-300.
43. Lee K.Y., Hwang J., Lee Y.W., Kim J., Han S.W. One-step synthesis of gold nanoparticles using azacryptand and their applications in SERS and catalysis. J. Colloid Interface Sci. 2007, 316:476-481.
44. Lee S.E., Liu G.L., Kim F., Lee L.P. Remote optical switch for localized and selective control of gene interference. Nano Lett. 2009, 9:562-570.
45. Lei C.-X., Gong F.-C., Shen G.-L., Yu R.-Q. Amperometric immunosensor for Schistosoma japonicum antigen using antibodies loaded on a nano-Au monolayer modified chitosan-entrapped carbon paste electrode. Sens. Actuators B Chem. 2003, 96:582-588.
46. Li Z., Capretto D.A., Rahaman R.O., He C. Gold(III)-catalyzed nitrene insertion into aromatic and benzylic C-H groups. J Am Chem Soc. 2007, 129:12058-12059.
47. Liu Y. Electrochemical detection of prostate-specific antigen based on gold colloids/alumina derived sol-gel film. Thin Solid Films 2008, 516:1803-1808.
48. 1 based bio-electrocatalytic reaction on microcomb-type electrode. Biochem. Eng. J. 2006, 32:211-217.
49. Luo Y. Size-controlled preparation of dendrimer-protected gold nanoparticles: a sunlight irradiation-based strategy. Mater. Lett. 2008, 62:3770-3772.
50. Luo Y., Li C.-J. A highly efficient gold/silver-catalyzed addition of arenes to imines. Chem. Commun. 2004, 1930-1931.
51. Mallick K., Wang Z.L., Pal T. Seed-mediated successive growth of gold particles accomplished by UV irradiation: a photochemical approach for size-controlled synthesis. J. Photochem. Photobiol. A: Chem. 2001, 140:75-80.
52. Maria A., Antonio A., Gabriele B., Fabio M., Antonella N. Gold-catalyzed C-3-alkylation of 7-azaindoles through michael-type addition to α,β-enones. Eur. J. Org. Chem. 2006, 2393-2402.
53. Mariko U., Mariko H.-S., Kingo U., Yasuhide N. Photo-control of the polyplexes formation between DNA and photo-cation generatable water-soluble polymers. Curr. Drug Deliv. 2005, 2:207-214.
54. Mazaahir K., Vikas B., Ajeet K., Subho M. The first Au-nanoparticles catalyzed green synthesis of propargylamines via a three-component coupling reaction of aldehyde, alkyne and amine. Green Chem. 2007, 9:742-745.
55. Mocellin S., Bronte V., Nitti D. Nitric oxide, a double edged sword in cancer biology: searching for therapeutic opportunities. Med. Res. Rev. 2007, 27:317-352.
56. Mukherjee P., Ahmad A., Mandal D., Senapati S. Fungus mediated synthesis of silver nanoparticles and their immobilization in the mycellial matrix: a novel biological approach to nano particle synthesis. Nano Lett. 2001, 1:515-519.
57. Nair B., Pradeep T. Coalescence of nanoclusters and formation of submicron crystallites assisted by lactobacillus strains. Cryst. Growth Des. 2002, 2:293-298.
58. Niidome Y., Niidome T., Yamada S., Horiguchi Y., Takahashi H., Nakashima K. Pulsed-laser induced fragmentation and dissociation of DNA immobilized on gold nanoparticles. Mol. Cryst. Liq. Cryst. 2006, 445:201/[491]-206/[496]. 491.
59. Noh S.M., Kim W.-K., Kim S.J., Kim J.M., Baek K.-H., Oh Y.-K. Enhanced cellular delivery and transfection efficiency of plasmid DNA using positively charged biocompatible colloidal gold nanoparticles. Biochim. Biophys. Acta 2007, 1770:747-752.
60. Note C., Kosmella S., Koetz J. Poly(ethyleneimine) as reducing and stabilizing agent for the formation of gold nanoparticles in w/o microemulsions. Colloids Surf. A 2006, 290:150-156.
61. Odenthal K.J., Gooding J.J. Electrochemical DNA biosensors. Analyst 2007, 132:603-610.
62. Paciotti G.F., Myer L., Weinreich D., Goia D., Pavel N., McLaughlin R.E., Tamarkin L. Colloidal gold: a novel nanoparticle vector for tumor directed drug delivery. Drug Deliv. 2004, 11:169-183.
63. Paciotti G.F., Kingston D.G.I., Tamarkin L. Colloidal gold nanoparticles: a novel nanoparticle platform for developing multifunctional tumor-targeted drug delivery vectors. Drug Dev. Res. 2006, 67:47-54.
64. Pal A., Shah S., Devi S. Preparation of silver, gold and silver-gold bimetallic nanoparticles in w/o microemulsion containing Triton X-100. Colloids Surf. A: Physicochem. Eng. Aspects 2007, 302:483-487.
65. Patra C.R., Bhattacharya R., Wang E., Katarya A., Lau J.S., Dutta S., Muders M., Wang S., Buhrow S.A., Safgren S.L., Yaszemski M.J., Reid J.M., Ames M.M., Mukgerjee P., Mukhopadhyay D. Targeted delivery of gemcitabine to pancreatic adenocarcinoma using cetuximab as a targeting agent. Cancer Res. 2008, 68:1970-1978.
66. Philip D. Biosynthesis of Au, Ag and Au-Ag nanoparticles using edible mushroom extract. Chimica. Acta Part A 2009, 73:374-381.
67. Pol V.G., Gedanken A., Calderro-Moreno J. Deposition of gold nanoparticles on silica spheres: a sonochemical approach. Chem. Mater. 2003, 15:1111-1118.
68. Polizzi M.A., Stasko N.A., Schoenfisch M.H. Water-soluble nitric oxide-releasing gold nanoparticles. Langmuir 2007, 23:4938-4943.
69. Reed J.A., Cook A., Halaas D.J., Parazolli P., Robinson A., Matula T.J., Griezer F. The effects of microgravity on nanoparticle size distributions generated by the ultrasonic reduction of an aqueous gold-chloride solution. Ultrason. Sonochem. 2003, 10:285-289.
70. Reetz M.T., Sommer K. Gold-catalyzed hydroarylation of alkynes. Eur. J. Org. Chem. 2003, 3485-3496.
71. Sau T.K., Pal A., Jana N.R., Wang Z.L., Pal T. Size controlled synthesis of gold nanoparticles using photochemically prepared seed particles. J. Nanopart. Res. 2001, 3:257-261.
72. Sawamura M., Nakayama Y., Kato T., Ito Y. Gold(I)-catalyzed asymmetric aldol reaction of an α-isocyano weinreb amide. An efficient synthesis of optically active ß-hydroxyl α-amino aldehydes and ketones. J. Org. Chem. 1995, 60:1727-1732.
73. Selvakannan P.R., Mandal S., Phadtare S., Gole A., Pasricha R., Adyanthaya S.D., Sastry M. Water-dispersible tryptophan-protected gold nanoparticles prepared by the spontaneous reduction of aqueous chloroaurate ions by the amino acid. J. Colloid Interface Sci. 2004, 269:97-102.
74. Shankar S.S., Ahmad A., Pasricha R., Sastry M. Bioreduction of chloroautate ions by geranium leaves and its endophytic fungus yields gold nanoparticles of different shapes. J. Mater. Chem. 2003, 13:1822-1826.
75. Shi Z., He C. An Au-catalyzed cyclialkylation of electron-rich arenes with epoxides to prepare 3-chromanols. J. Am. Chem. Soc. 2004, 126:5964-5965.
76. Shi Z., He C. Direct functionalization of arenes by primary alcohol sulfonate esters catalyzed by gold(III). J. Am. Chem. Soc. 2004, 126:13596-13597.
77. Shih C.-M., Shieh Y.-T., Twu Y.-K. Preparation of gold nanopowders and nanoparticles using chitosan suspensions. Carbohydr. Polym. 2009, 78:309-315.
78. Shul'pin G.B., Suess-Fink G., Shilov A.E. Alkane oxygenation catalysed by gold complexes. Tetrahedron Lett. 2001, 42:7253-7256.
79. Skirtach A.G., Javier A.M., Kreft O., Kohler K., Alberola A.P., Mohwald H., Parak W.J., Sukhorukov G.B. Laser-induced release of encapsulated materials inside living cells. Angew. Chem. Int. Ed. 2006, 45:4612-4617.
80. Sönnichsen C., Franzl T., Wilk T., Plessen G.V., Feldmann J., Wilson O., Mulvaney P. Drastic reduction of plasmon damping in gold nanorods. Phys. Rev. Lett. 2002, 88:077402/1.
81. Stephan L., Mostafa A.E. Optical properties and ultrafast dynamics of metallic nanocrystals. Annu. Rev. Phys. Chem. 2003, 54:331-366.
82. Stephen L., Mostafa A.E. Oscillations in gold and silver nano-dots and nano-rods. J. Phys. Chem. B 1999, 103:8410-8426.
83. Stephen L., Mostafa A.E. Shape and size dependence of radiative, nonradiative, and photothermal properties of gold nanocrystals. Int. Rev. Phys. Chem. 2000, 19:409-433.
84. Stephen L., Mostafa A.E. Optical spectroscopy of surface plasmons in metal nanoparticles. Semiconductor and Metal Nanocrystals: Synthesis and Electronic and Optical Properties 2004, 239-288. Marcel Dekker, New York. V.I. Klimov (Ed.).
85. Sun K., Qiu J., Liu J., Miao Y. Preparation and characterization of gold nanoparticles using ascorbic acid as reducing agent in reverse micelles. J. Mater. Sci. 2009, 44:754-758.
86. Tang D., Yuan T.R., Chai Y., Fu Y., Dai J., Liu Y., Zhong X. New amperometric and potentiometric immunosensors based on gold nanoparticles/tris(2,2'-bipyridyl)cobalt(III) multilayer films for hepatitis B surface antigen determinations. Biosens. Bioelectron. 2005, 21:539-548.
87. Tang D., Yuan R., Chai Y., Zhong X., Liu Y., Dai J. Electrochemical detection of hepatitis B surface antigen using colloidal gold nanoparticles modified by a sol-gel network interface. Clin. Biochem. 2006, 39:309-314.
88. Teles J.H., Brode S., Chabanas M. Cataionic Gold(I) complexes: highly efficient catalysts for the addition of alcohols to alkynes. Angew. Chem. Int. Ed. 1998, 37:1415-1418.
89. Thompson D. New advances in gold catalysis part II. Gold Bull. 1999, 32:12-19.
90. Turkevitch J., Stevenson P.C., Hillier J. Nucleation and growth process in the synthesis of colloidal gold. Discuss. Faraday Soc. 1951, 11:55-75.
91. Vaškelis A., Tarozaite R., Jagminiene A., Tamašiūnaite L.T., Juškenas R., Kurtinaitiene M. Gold nanoparticles obtained by Au(III) reduction with Sn(II): preparation and electrocatalytic properties in oxidation of reducing agents. Electrochim. Acta 2007, 53:407-416.
92. Verma A., Simard J.M., Worrall J.W.E., Rotello V.M. Tunable reactivation of nanoparticle-inhibited beta-galactosidase by glutathione at intracellular concentrations. J. Am. Chem. Soc. 2004, 126:13987-13991.
93. Wagner J., Tshikhudo T.R., Köhler J.M. Microfluidic generation of metal nanoparticles by borohydride reduction. Chem. Eng. J. 2008, 135:S104-S109.
94. Wang W., Breining T., Li T., Milbum R., Attardo G. Dehydrogenation by air: preparation of 1, 3-disubstituted-5,1-dioxo-5,10-dihydro-1H-benzo[g] isochromene scaffold. Tetrahedron Lett. 1998, 39:2459-2462.
95. Wang M., Wang L., Wang G., Ji X., Bai Y., Li T., Gong S., Li J. Application of impedance spectroscopy for monitoring colloid Au-enhanced antibody immobilization and antibody-antigen reactions. Biosens. Bioelectron. 2004, 19:575.
96. Wang W., Chena O., Jiang C., Yang D., Liu X., Xua S. One-step synthesis of biocompatible gold nanoparticles using gallic acid in the presence of poly-(N-vinyl-2-pyrrolidone). Colloids Surf. A: Physicochem. Eng. Aspects 2007, 301:73-79.
97. Wei C., Li C.-J. A highly efficient three-component coupling of aldehyde, alkyne, and amines via C-H activation catalyzed by gold in water. J. Am. Chem. Soc. 2003, 125:9584-9585.
98. Wei C., Li C.-J. Gold-catalyzed coupling of alkynes and acyl iminiums. Lett. Org. Chem. 2005, 2:410-414.
99. Xia C., Zhi-Feng X., Xin F., Shi-Ping W., Guo-Li S., Ru-Qin Y. Silver-enhanced colloidal gold metalloimmunoassay for Schistosoma japonicum antibody detection. J. Immunol. Methods 2005, 301:77-88.
100. Xiao-Hong F. Electrochemical immunoassay for carbohydrate antigen-125 based on polythionine and gold hollow microspheres modified glassy carbon electrodes. Electroanalysis 2007, 1831-1839.
101. Xiaohua H., Prashant K.J., Ivan H.El.-S., Mostafa A.El.-S. Determination of the minimum temperature required for selective photothermal destruction of cancer cells with the use of immunotargeted gold nanoparticles. Photochem. Photobiol. 2006, 82:412-417.
102. Xiaohua H., Prashant K.J., Ivan H.El.-S., Mostafa A.El.-S. Plasmonic photothermal therapy (PPTT) using gold nanoparticles. Lasers Med. Sci. 2008, 23:217-228.
103. 3)]. Chem. Lett. 2003, 32:452-453.
104. Yan B., Liu Y. Gold-catalyzed multicomponent synthesis of aminoindolizines from aldehydes, amines, and alkynes under solvent-free conditions or in water. Org. Lett. 2007, 9:4323-4326.
105. Yang Q., Wang S.H., Fan P.W., Wang L.F., Di Y., Lin K.F., Xiao F.S. pH-responsive carrier system based on carboxylic acid modified mesoporous silica and polyelectrolyte for drug delivery. Chem. Mater. 2005, 17:5999-6003.
106. Yao X., Li C.-J. Water-triggered and gold(I)-catalyzed cascade addition/cyclization of terminal alkynes with ortho-alkynylaryl aldehyde. Org. Lett. 2006, 8:1953-1955.
107. Yguerabide J., Yguerabide E.E. Light-scattering submicroscopic particles as highly fluorescent analogs and their use as tracer labels in clinical and biological applications. Anal. Biochem. 1998, 262:137-156.
108. Ying Z., Ruo Y., Yaqin C., Dianping T., Ying Z., Na W., Xuelian L., Qiang Z. A reagentless amperometric immunosensor based on gold nanoparticles/thionine/nafion-membrane-modified gold electrode for determination of α-1-fetoprotein. Electrochem. Commun. 2005, 7:355-360.
109. Zhao R., Ji D., Lv G., Qian G., Yan L., Wang X., Suo J. A highly efficient oxidation of cyclohexane over Au/ZSM-5 molecular sieve catalyst with oxygen as oxidant. Chem. Commun. 2004, 7:904-905.
110. Zhuo Y., Yuan R., Chai Y., Zhang Y., Wang N., Li X., Zhu Q., Wang N. An amperometric immunosensor based on immobilization of hepatitis B surface antibody on gold electrode modified gold nanoparticles and horseradish peroxidase. Anal. Chim. Acta 2005, 548:205-210.