Temporal dynamics of cerebrospinal fluid anti-aquaporin-4 antibodies in patients with neuromyelitis optica spectrum disorders

Journal of Neuroimmunology

Volumn 234, Issue 1-2, 2011, Pages 124-130

  Dujmovic, Irena ^a,b   Mader, Simone ^b   Schanda, Kathrin ^b   Deisenhammer, Florian ^b   Stojsavljevic, Nebojsa ^a   Kostic, Jelena ^a   Berger, Thomas ^b   Drulovic, Jelena ^a,c   Reindl, Markus ^b  

^a CLINICAL CENTER OF SERBIA   (Serbia)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Aquaporin 4; Cerebrospinal fluid; Clinical activity; Longitudinal study; Neuromyelitis optica

Indexed keywords

AQUAPORIN 4; AQUAPORIN 4 ANTIBODY; AZATHIOPRINE; CYCLOPHOSPHAMIDE; IMMUNOGLOBULIN G; METHYLPREDNISOLONE; PREDNISONE; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DRUG MEGADOSE; EXPANDED DISABILITY STATUS SCALE; FEMALE; HUMAN; MALE; MOLECULAR DYNAMICS; MYELOOPTIC NEUROPATHY; PLASMAPHERESIS; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADULT; AGED; AQUAPORIN 4; CELL COUNT; CELL LINE, TRANSFORMED; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; NEUROMYELITIS OPTICA; NONLINEAR DYNAMICS; YOUNG ADULT;

EID: 79955657783     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2011.01.007     Document Type: Article

References (21)

1. Bennett J.L., Lam C., Kalluri S.R., Saikali P., Bautista K., Dupree C., Glogowska M., Case D., Antel J.P., Owens G.P., Gilden D., Nessler S., Stadelmann C., Hemmer B. Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica. Ann. Neurol. 2009, 66:617-629.
2. Bradl M., Misu T., Takahashi T., Watanabe M., Mader S., Reindl M., Adzemovic M., Bauer J., Berger T., Fujihara K., Itoyama Y., Lassmann H. Neuromyelitis optica: pathogenicity of patient immunoglobulin in vivo. Ann. Neurol. 2009, 66:630-643.
3. Graber D.J., Levy M., Kerr D., Wade W.F. Neuromyelitis optica pathogenesis and aquaporin 4. J. Neuroinflammation 2008, 5:22.
4. Hinson S.R., Pittock S.J., Lucchinetti C.F., Roemer S.F., Fryer J.P., Kryzer T.J., Lennon V.A. Pathogenic potential of IgG binding to water channel extracellular domain in neuromyelitis optica. Neurology 2007, 69:2221-2231.
5. Hinson S.R., Roemer S.F., Lucchinetti C.F., Fryer J.P., Kryzer T.J., Chamberlain J.L., Howe C.L., Pittock S.J., Lennon V.A. Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2. J. Exp. Med. 2008, 205:2473-2481.
6. Jarius S., Franciotta D., Bergamaschi R., Wright H., Littleton E., Palace J., Hohlfeld R., Vincent A. NMO-IgG in the diagnosis of neuromyelitis optica. Neurology 2007, 68:1076-1077.
7. Jarius S., Aboul-Enein F., Waters P., Kuenz B., Hauser A., Berger T., Lang W., Reindl M., Vincent A., Kristoferitsch W. Antibody to aquaporin-4 in the long-term course of neuromyelitis optica. Brain 2008, 131:3072-3080.
8. Jarius S., Franciotta D., Paul F., Ruprecht K., Bergamaschi R., Rommer P.S., Reuss R., Probst C., Kristoferitsch W., Wandinger K.P., Wildemann B. Cerebrospinal fluid antibodies to aquaporin-4 in neuromyelitis optica and related disorders: frequency, origin, and diagnostic relevance. J. Neuroinflammation 2010, 7:52.
9. Kinoshita M., Nakatsuji Y., Kimura T., Moriya M., Takata K., Okuno T., Kumanogoh A., Kajiyama K., Yoshikawa H., Sakoda S. Neuromyelitis optica: passive transfer to rats by human immunoglobulin. Biochem. Biophys. Res. Commun. 2009, 386:623-627.
10. Klawiter E.C., Alvarez E., Xu J., Paciorkowski A.R., Zhu L., Parks B.J., Cross A.H., Naismith R.T. NMO-IgG detected in CSF in seronegative neuromyelitis optica. Neurology 2009, 72:1101-1103.
11. Lennon V.A., Wingerchuk D.M., Kryzer T.J., Pittock S.J., Lucchinetti C.F., Fujihara K., Nakashima I., Weinshenker B.G. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 2004, 364:2106-2112.
12. Mader S., Lutterotti A., Di Pauli F., Kuenz B., Schanda K., Aboul-Enein F., Khalil M., Storch M.K., Jarius S., Kristoferitsch W., Berger T., Reindl M. Patterns of antibody binding to aquaporin-4 isoforms in neuromyelitis optica. PLoS ONE 2010, 5:e10455.
13. Matiello M., Lennon V.A., Jacob A., Pittock S.J., Lucchinetti C.F., Wingerchuk D.M., Weinshenker B.G. NMO-IgG predicts the outcome of recurrent optic neuritis. Neurology 2008, 70:2197-2200.
14. Misu T., Takano R., Fujihara K., Takahashi T., Sato S., Itoyama Y. Marked increase in cerebrospinal fluid glial fibrillar acidic protein in neuromyelitis optica: an astrocytic damage marker. J. Neurol. Neurosurg. Psychiatry 2009, 80:575-577.
15. Saadoun S., Waters P., Bell B.A., Vincent A., Verkman A.S., Papadopoulos M.C. Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice. Brain 2010, 133:349-361.
16. Saikali P., Cayrol R., Vincent T. Anti-aquaporin-4 auto-antibodies orchestrate the pathogenesis in neuromyelitis optica. Autoimmun. Rev. 2009, 9:132-135.
17. Scott T.F., Kassab S.L., Pittock S.J. Neuromyelitis optica IgG status in acute partial transverse myelitis. Arch. Neurol. 2006, 63:1398-1400.
18. Takahashi T., Fujihara K., Nakashima I., Misu T., Miyazawa I., Nakamura M., Watanabe S., Ishii N., Itoyama Y. Establishment of a new sensitive assay for anti-human aquaporin-4 antibody in neuromyelitis optica. Tohoku J. Exp. Med. 2006, 210:307-313.
19. Takahashi T., Fujihara K., Nakashima I., Misu T., Miyazawa I., Nakamura M., Watanabe S., Shiga Y., Kanaoka C., Fujimori J., Sato S., Itoyama Y. Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre. Brain 2007, 130:1224-1234.
20. Vincent T., Saikali P., Cayrol R., Roth A.D., Bar-Or A., Prat A., Antel J.P. Functional consequences of neuromyelitis optica-IgG astrocyte interactions on blood-brain barrier permeability and granulocyte recruitment. J. Immunol. 2008, 181:5730-5737.
21. Wingerchuk D.M., Lennon V.A., Pittock S.J., Lucchinetti C.F., Weinshenker B.G. Revised diagnostic criteria for neuromyelitis optica. Neurology 2006, 66:1485-1489.