POTEH hypomethylation, a new epigenetic biomarker for glioma prognosis

Brain Research

Volumn 1391, Issue , 2011, Pages 125-131

  Liu, Xiaoping ^a   Tang, Hailin ^a,b   Zhang, Zuping ^a   Li, Wenjuan ^a   Wang, Zeyou ^a   Zheng, Ying ^a   Wu, Minghua ^a   Li, Guiyuan ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Glioma; Hypomethylation; POTEH; Prognosis

Indexed keywords

BIOLOGICAL MARKER; GENOMIC DNA; POTE ANKYRIN DOMAIN FAMILY MEMBER H; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL TRIAL; EPIGENETICS; FEMALE; FOLLOW UP; GLIOMA; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; METHYLATION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; SURVIVAL;

ADOLESCENT; ADULT; ANTIGENS, NEOPLASM; BIOLOGICAL MARKERS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CHILD; CHILD, PRESCHOOL; DNA METHYLATION; EPIGENOMICS; FEMALE; FOLLOW-UP STUDIES; GLIOMA; HUMANS; MALE; MIDDLE AGED; PROTEINS; YOUNG ADULT;

EID: 79955628648     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.03.042     Document Type: Article

References (21)

1. Bera, T.K., et al., 2006. POTE paralogs are induced and differentially expressed in many cancers. Cancer Res. 66, 52-56. (Pubitemid 43166008)
2. Bera, T.K., et al., 2002. POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta and prostate cancer. Proc. Natl Acad. Sci. U.S.A. 99, 16975-16980.
3. Cadieux, B., et al., 2006. Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation. Cancer Res. 66, 8469-8476. (Pubitemid 44449159)
4. Costello, J.F., et al., 2000. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat. Genet. 24, 132-138.
5. De Smet, C., et al., 1996. The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation. Proc. Natl Acad. Sci. U.S.A. 93, 7149-7153.
6. Fanelli, M., et al., 2008. Loss of pericentromeric DNA methylation pattern in human glioblastoma is associated with altered DNA methyltransferases expression and involves the stem cell compartment. Oncogene 27, 358-565.
7. Foltz, G., et al., 2006. Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma. Cancer Res. 66, 6665-6674. (Pubitemid 44085623)
8. Jones, P.A., Baylin, S.B., 2007. The epigenomics of cancer. Cell 128, 683-692. (Pubitemid 46273572)
9. Kim, T.Y., et al., 2006. Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Res. 66, 7490-7501.
10. Nagarajan, R.P., Costello, J.F., 2009. Epigenetic mechanisms in glioblastoma multiforme. Semin. Cancer Biol. 19, 188-197.
11. Oshimo, Y., et al., 2003. Promoter methylation of cyclin D2 gene in gastric carcinoma. Int. J. Oncol. 23, 1663-1670.
12. Raman, P.N., Joseph, F.C., 2009. Epigenetic mechanisms in glioblastoma multiforme. Seminars Cancer Biol. 19, 188-197.
13. Reed, K., et al., 2008. Hypermethylation of the ABCB1 downstream gene promoter accompanies ABCB1 gene amplification and increased expression in docetaxel-resistant MCF-7 brain tumor cells. Epigenetics 3, 270-280.
14. Sanai, N., et al., 2005. New stem cells and the origin of gliomas. N. Engl. J. Med. 353 (8), 811-822.
15. Schwartzbaum, J.A., et al., 2006. Epidemiology and molecular pathology of glioma. Nat. Clin. Pract. Neurol. 2 (9), 494-503.
16. Tapan, K.B., et al., 2004. Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths. Gene 337, 45-53.
17. Uhlmann, K., et al., 2003. Distinct methylation profiles of glioma subtypes. Int. J. Cancer 106, 52-59. (Pubitemid 36750387)
18. Xiwei, W., et al., 2010. CpG island hypermethylation in human astrocytomas. Cancer Res. 70 (7), 2718-2727.
19. Yu, J., et al., 2004. Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma. BMC Cancer 4, 65.
20. Yoomi, L., et al., 2006. Evolution and expression of chimeric POTE-actin genes in the human genome. PNAS. 103 (47), 17885-17890.
21. Ziad, J.S., et al., 2010. Tumor suppressor RARRES1 regulates DLG2, PP2A, VGP, EB1, and ANkrd26. J. Cancer 1, 14-22.