Protein unfolding accounts for the unusual mechanical behavior of fibrin networks

Acta Biomaterialia

Volumn 7, Issue 6, 2011, Pages 2374-2383

  Purohit, Prashant K ^a   Litvinov, Rustem I ^c   Brown, Andre E X ^b   Discher, Dennis E ^a,b   Weisel, John W ^c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Blood clots; Constitutive model; Nanomechanics; Poisson's ratio; Viscoelasticity

Indexed keywords

CHAINS; COMPRESSIBILITY; NANOMECHANICS; POISSON RATIO;

BLOOD CLOTS; CHAIN MODELS; FIBRIN NETWORK; FORCE RESPONSE; ISOTROPICS; MACROSCOPIC SCALE; MECHANICAL BEHAVIOR; NANO SCALE; PROTEIN UNFOLDING;

MOLECULES;

BLOOD CLOTTING FACTOR 13; CALCIUM ION; FIBRIN; FIBRINOGEN; THROMBIN;

ALPHA CHAIN; ARTICLE; BETA CHAIN; CARBOXY TERMINAL SEQUENCE; CHICKEN; COMPRESSIVE STRENGTH; CONTROLLED STUDY; COW; EIGHT CHAIN MODEL; ENERGY; HUMAN; INFRARED SPECTROSCOPY; LAMPREY; MATERIALS TESTING; MECHANICAL STRESS; MOLECULAR MECHANICS; MOLECULAR MODEL; NANOANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN UNFOLDING; QUANTITATIVE ANALYSIS; RADIATION SCATTERING; RNA TRANSLATION; SCANNING ELECTRON MICROSCOPE; SPECIES DIFFERENCE; TENSILE STRENGTH;

EID: 79955626596     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.02.026     Document Type: Article

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