Indications for Blood Transfusion in Cardiac Surgery

Annals of Thoracic Surgery

Volumn 82, Issue 6, 2006, Pages 2323-2334

  Murphy, Gavin J ^a   Angelini, Gianni D ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN;

BLOOD TRANSFUSION; CELL HYPOXIA; CLINICAL FEATURE; ERYTHROCYTE TRANSFUSION; HEART SURGERY; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HEMOGLOBIN DETERMINATION; HEMORRHAGIC SHOCK; HUMAN; IMMUNOMODULATION; LEUKOPENIA; LUNG INJURY; OUTCOME ASSESSMENT; OXYGEN SUPPLY; PATHOPHYSIOLOGY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; TISSUE OXYGENATION; TREATMENT INDICATION;

ADULT; ANEMIA; CARDIAC SURGICAL PROCEDURES; CELL HYPOXIA; ERYTHROCYTE TRANSFUSION; HEMOGLOBINS; HUMANS;

EID: 33751182560     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2006.06.020     Document Type: Review

References (83)

1. Stover E.P., Siegel L.C., Parks R., et al., Institutions of the Multicenter Study of Perioperative Ischemia Research Group. Variability in transfusion practice for coronary artery bypass surgery persists despite national consensus guidelines: a 24-institution study. Anesthesiology 88 (1998) 327-333
2. Moise S.F., Higgins M.J., and Colquhoun A.D. A survey of blood transfusion practice in UK cardiac surgery units. Crit Care 5 Suppl A (2001) 5
3. Habib R.H., Zacharias A., Schwann T.A., Riordan C.J., Durham S.J., and Shah A. Adverse effects of low hematocrit during cardiopulmonary bypass in the adult: should current practice be changed?. J Thorac Cardiovasc Surg 125 (2003) 1438-1450
4. Ranucci M., Romitti F., Isgro G., et al. Oxygen delivery during cardiopulmonary bypass and acute renal failure after coronary operations. Ann Thorac Surg 80 (2005) 2213-2220
5. Casutt M., Seifert B., Pasch T., Schmid E.R., Turina M.I., and Spahn D.R. Factors influencing the individual effects of blood transfusions on oxygen delivery and oxygen consumption. Crit Care Med 27 (1999) 2194-2200
6. Zindrou D., Taylor K.M., and Bagger J.P. Preoperative hemoglobin concentration and mortality rate after coronary artery bypass surgery. Lancet 359 (2002) 1747-1748
7. Ferraris V.A., and Ferraris S.P. Risk factors for postoperative morbidity. J Thorac Cardiovasc Surg 111 (1996) 731-738
8. Licker M., Ellenberger C., Sierra J., Kalangos A., Diaper J., and Morel D. Cardioprotective effects of acute normovolemic hemodilution in patients undergoing coronary artery bypass surgery. Chest 128 (2005) 838-847
9. Habib R.H., Zacharias A., Schwann T.A., et al. Role of hemodilutional anemia and transfusion during cardiopulmonary bypass in renal injury after coronary revascularization: implications on operative outcome. Crit Care Med 33 (2005) 1749-1756
10. Karkouti K., Wijeysundera D.N., Yau T.M., et al. The independent association of massive blood loss with mortality in cardiac surgery. Transfusion 44 (2004) 1453-1462
11. Karkouti K., Djaiani G., Borger M.A., et al. Low hematocrit during cardiopulmonary bypass is associated with increased risk of perioperative stroke in cardiac surgery. Ann Thorac Surg 80 (2005) 1381-1387
12. Dial S., Delabays E., Albert M., et al. Hemodilution and surgical hemostasis contribute significantly to transfusion requirements in patients undergoing coronary artery bypass. J Thorac Cardiovasc Surg 130 (2005) 654-661
13. Swaminathan M., Phillips-Bute B.G., Conlon P.J., Smith P.K., Newman M.F., and Stafford-Smith M. The association of lowest hematocrit during cardiopulmonary bypass with acute renal injury after coronary artery bypass surgery. Ann Thorac Surg 76 (2003) 784-791
14. DeFoe G.R., Ross C.S., Olmstead E.M., et al., Northern New England Cardiovascular Disease study group. Lowest hematocrit on bypass and adverse outcomes associated with coronary artery bypass grafting. Ann Thorac Surg 71 (2001) 769-776
15. van Wermeskerken G.K., Lardenoye J.W., Hill S.E., et al. Intraoperative physiologic variables and outcome in cardiac surgery: part II. Neurologic outcome. Ann Thorac Surg 69 (2000) 1077-1083
16. Hill S.E., van Wermeskerken G.K., Lardenoye J.W., et al. Intraoperative physiologic variables and outcome in cardiac surgery: part I. In-hospital mortality. Ann Thorac Surg 69 (2000) 1070-1075
17. Fang W.C., Helm R.E., Krieger K.H., et al. Impact of minimum hematocrit during cardiopulmonary bypass on mortality in patients undergoing coronary artery surgery. Circulation 96 Suppl 2 (1997) 194-199
18. Klass O., Mehlhorn U., Zilkens K., et al. Impact of hematocrit value after coronary artery surgery on perioperative myocardial infarction rate. Thorac Cardiovasc Surg 50 (2002) 259-265
19. Bracey A.W., Radovancevic R., Riggs S.A., et al. Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: effect on patient outcome. Transfusion 39 (1999) 1070-1077
20. Spiess B.D., Ley C., Body S.C., et al., The Institutions of the Multicenter Study of Perioperative Ischemia (McSPI) research group. Hematocrit value on intensive care unit entry influences the frequency of Q-wave myocardial infarction after coronary artery bypass grafting. J Thorac Cardiovasc Surg 116 (1998) 460-467
21. Rady M.Y., Ryan T., and Starr N.J. Early onset of acute pulmonary dysfunction after cardiovascular surgery: risk factors and clinical outcome. Crit Care Med 25 (1997) 1831-1839
22. Utoh J., Goto H., Obayashi H., Hirati T., and Miyauchi Y. Oxygen metabolism after cardiopulmonary bypass. J Cardiovasc Surg 37 Suppl 1 (1996) 119-120
23. Boston U.S., Slater J.M., Orszulak T.A., and Cook D.J. Hierarchy of regional oxygen delivery during cardiopulmonary bypass. Ann Thorac Surg 71 (2001) 260-264
24. Hebert P.C., Wells G., Blajchman M.A., et al., Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 340 (1999) 409-417
25. Sabatine M.S., Morrow D.A., Giugliano R.P., et al. Association of hemoglobin levels with clinical outcomes in acute coronary syndromes. Circulation 111 (2005) 2042-2049
26. Wu W.C., Rathore S.S., Wang Y., Radford M.J., and Krumholz H.M. Blood transfusion in elderly patients with acute myocardial infarction. N Engl J Med 345 (2001) 1230-1236
27. Hebert P.C., Wells G., Tweeddale M., et al. Does transfusion practice affect mortality in critically ill patients?. Am J Respir Crit Care Med 155 (1997) 1618-1623
28. Carson J.L., Duff A., Poses R.M., et al. Effect of anaemia and cardiovascular disease on surgical mortality and morbidity. Lancet 348 (1996) 1055-1060
29. Liam B.L., Plochl W., Cook D.J., Orszulak T.A., and Daly R.C. Hemodilution and whole body oxygen balance during normothermic cardiopulmonary bypass in dogs. J Thorac Cardiovasc Surg 115 (1998) 1203-1208
30. Cook D.J., Orszulak T.A., Daly R.C., and MacVeigh I. Minimum hematocrit for normothermic cardiopulmonary bypass in dogs. Circulation 96 Suppl 2 (1997) 200-204
31. Jonas R.A., Wypij D., Roth S.J., et al. The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: results of a randomized trial in infants. J Thorac Cardiovasc Surg 126 (2003) 1765-1774
32. Ganushchak Y.M., Fransen E.J., Visser C., De Jong D.S., and Maessen J.G. Neurological complications after coronary artery bypass grafting related to the performance of cardiopulmonary bypass. Chest 125 (2004) 2196-2205
33. McLoughlin T.M., Fontana J.L., Alving B., Mongan P.D., and Bunger R. Profound normovolemic hemodilution: hemostatic effects in patients and in a porcine model. Anesth Analg 83 (1996) 459-465
34. van Bommel J., Trouwborst A., Schwarte L., Siegemund M., Ince C., and Henny Ch.P. Intestinal and cerebral oxygenation during severe isovolemic hemodilution and subsequent hyperoxic ventilation in a pig model. Anesthesiology 97 (2002) 660-670
35. Weiskopf R.B., Kramer J.H., Viele M., et al. Acute severe isovolemic anemia impairs cognitive function and memory in humans. Anesthesiology 92 (2000) 1646-1652
36. Leung J.M., Weiskopf R.B., Feiner J., et al. Electrocardiographic ST-segment changes during acute, severe isovolemic hemodilution in humans. Anesthesiology 93 (2000) 1004-1010
37. Homi H.M., Yang H., Pearlstein R.D., and Grocott H.P. Hemodilution during cardiopulmonary bypass increases cerebral infarct volume after middle cerebral artery occlusion in rats. Anesth Analg 99 (2004) 974-981
38. Habler O.P., Kleen M.S., Podtschaske A.H., et al. The effect of acute normovolemic hemodilution (ANH) on myocardial contractility in anesthetized dogs. Anesth Analg 83 (1996) 451-458
39. Licker M., Mariethoz E., Costa M.J., and Morel D. Cardioprotective effects of acute isovolemic hemodilution in a rat model of transient coronary occlusion. Crit Care Med 33 (2005) 2302-2308
40. Licker M., Ellenberger C., Sierra J., Christenson J., Diaper J., and Morel D. Cardiovascular response to acute normovolemic hemodilution in patients with coronary artery diseases: assessment with transesophageal echocardiography. Crit Care Med 33 (2005) 591-597
41. Schou H., Kongstad L., Perez de Sa V., Werner O., and Larsson A. Uncompensated blood loss is not tolerated during acute normovolemic hemodilution in anesthetized pigs. Anesth Analg 87 (1998) 786-794
42. Banbury M.K., Brizzio M.E., Rajeswaran J., Lytle B.W., and Blackstone E.H. Transfusion increases the risk of postoperative infection after cardiovascular surgery. J Am Coll Surg 202 (2006) 131-138
43. Sreeram G.M., Welsby I.J., Sharma A.D., Phillips-Bute B., Smith P.K., and Slaughter T.F. Infectious complications after cardiac surgery: lack of association with fresh frozen plasma or platelet transfusions. J Cardiothorac Vasc Anesth 19 (2005) 430-434
44. Kuduvalli M., Oo A.Y., Newall N., et al. Effect of peri-operative red blood cell transfusion on 30-day and 1-year mortality following coronary artery bypass surgery. Eur J Cardiothorac Surg 27 (2005) 592-598
45. Ali Z.A., Lim E., Motalleb-Zadeh R., et al. Allogenic blood transfusion does not predispose to infection after cardiac surgery. Ann Thorac Surg 78 (2004) 1542-1546
46. Crabtree T.D., Codd J.E., Fraser V.J., Bailey M.S., Olsen M.A., and Damiano Jr. R.J. Multivariate analysis of risk factors for deep and superficial sternal infection after coronary artery bypass grafting at a tertiary care medical center. Semin Thorac Cardiovasc Surg 16 (2004) 53-61
47. Bove T., Calabro M.G., Landoni G., et al. The incidence and risk of acute renal failure after cardiac surgery. J Cardiothorac Vasc Anesth 18 (2004) 442-445
48. Talbot T.R., D'Agata E.M., Brinsko V., Lee B., Speroff T., and Schaffner W. Perioperative blood transfusion is predictive of poststernotomy surgical site infection: marker for morbidity or true immunosuppressant?. Clin Infect Dis 38 (2004) 1378-1382
49. Bucerius J., Gummert J.F., Walther T., et al. On-pump versus off-pump coronary artery bypass grafting: impact on postoperative renal failure requiring renal replacement therapy. Ann Thorac Surg 77 (2004) 1250-1256
50. Bucerius J., Gummert J.F., Borger M.A., et al. Predictors of delirium after cardiac surgery delirium: effect of beating-heart (off-pump) surgery. J Thorac Cardiovasc Surg 127 (2004) 57-64
51. Sharma A.D., Slaughter T.F., Clements F.M., et al. Association of leukocyte-depleted blood transfusions with infectious complications after cardiac surgery. Surg Infect (Larchmt) 3 (2002) 127-133
52. Engoren M.C., Habib R.H., Zacharias A., Schwann T.A., Riordan C.J., and Durham S.J. Effect of blood transfusion on long-term survival after cardiac operation. Ann Thorac Surg 74 (2002) 1180-1186
53. Olsen M.A., Lock-Buckley P., Hopkins D., Polish L.B., Sundt T.M., and Fraser V.J. The risk factors for deep and superficial chest surgical-site infections after coronary artery bypass graft surgery are different. J Thorac Cardiovasc Surg 124 (2002) 136-145
54. Chelemer S.B., Prato B.S., Cox Jr. P.M., O'Connor G.T., and Morton J.R. Association of bacterial infection and red blood cell transfusion after coronary artery bypass surgery. Ann Thorac Surg 73 (2002) 138-142
55. Vamvakas E.C., and Carven J.H. Allogeneic blood transfusion and postoperative duration of mechanical ventilation: effects of red cell supernatant, platelet supernatant, plasma components and total transfused fluid. Vox Sang 82 (2002) 141-149
56. Leal-Noval S.R., Rincon-Ferrari M.D., Garcia-Curiel A., et al. Transfusion of blood components and postoperative infection in patients undergoing cardiac surgery. Chest 119 (2001) 1461-1468
57. Vamvakas E.C., and Carven J.H. RBC transfusion and postoperative length of stay in the hospital or the intensive care unit among patients undergoing coronary artery bypass graft surgery: the effects of confounding factors. Transfusion 40 (2000) 832-839
58. Leal-Noval S.R., Marquez-Va'caro J.A., Garcia-Curiel A., et al. Nosocomial pneumonia in patients undergoing heart surgery. Crit Care Med 28 (2000) 935-940
59. Michalopoulos A., Tzelepis G., Dafni U., and Geroulanos S. Determinants of hospital mortality after coronary artery bypass grafting. Chest 115 (1999) 1598-1603
60. Ryan T., McCarthy J.F., Rady M.Y., et al. Early bloodstream infection after cardiopulmonary bypass: frequency rate, risk factors, and implications. Crit Care Med 25 (1997) 2009-2014
61. Habib R.H., Zacharias A., and Engoren M. Determinants of prolonged mechanical ventilation after coronary artery bypass grafting. Ann Thorac Surg 62 (1996) 1164-1171
62. Vincent J.L., Baron J.F., Reinhart K., et al. Anemia and blood transfusion in critically ill patients. JAMA 288 (2002) 1499-1507
63. Corwin H.L., Gettinger A., Pearl R.G., et al. The CRIT study: anemia and blood transfusion in the critically ill-current clinical practice in the United States. Crit Care Med 32 (2004) 39-52
64. Yang X., Alexander K.P., Chen A.Y., et al. The implications of blood transfusions for patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE national quality improvement initiative. J Am Coll Cardiol 46 (2005) 1490-1495
65. Suttner S., Piper S.N., Kumle B., et al. The influence of allogeneic red blood cell transfusion compared with 100% oxygen ventilation on systemic oxygen transport and skeletal muscle oxygen tension after cardiac surgery. Anesth Analg 99 (2004) 2-11
66. Tsai A.G., Cabrales P., and Intaglietta M. Microvascular perfusion upon exchange transfusion with stored red blood cells in normovolemic anemic conditions. Transfusion 44 (2004) 1626-1634
67. Marik P.E., and Sibbald W.J. Effect of stored-blood transfusion on oxygen delivery in patients with sepsis. JAMA 269 (1993) 3024-3029
68. Mazza B.F., Machado F.R., Mazza D.D., and Hassmann V. Evaluation of blood transfusion effects on mixed venous oxygen saturation and lactate levels in patients with SIRS/sepsis. Clinics 60 (2005) 311-316
69. d'Almeida M.S., Jagger J., Duggan M., et al. A comparison of biochemical and functional alterations of rat and human erythrocytes stored in CPDA-1 for 29 days: implications for animal models of transfusion. Transfus Med 10 (2000) 291-303
70. Crawford J.H., Isbell T.S., Huang Z., et al. Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation. Blood 107 (2006) 566-574
71. Fransen E., Maessen J., Dentener M., Senden N., and Buurman W. Impact of blood transfusions on inflammatory mediator release in patients undergoing cardiac surgery. Chest 116 (1999) 1233-1239
72. Silliman C.C., Voelkel N.F., Allard J.D., et al. Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model. J Clin Invest 101 (1998) 1458-1467
73. Simak J., and Gelderman M.P. Cell membrane microparticles in blood and blood products: potentially pathogenic agents and diagnostic markers. Trans Med Rev 20 (2006) 1-26
74. Covin R.B., Ambruso D.R., England K.M., et al. Hypotension and acute pulmonary insufficiency following transfusion of autologous red blood cells during surgery: a case report and review of the literature. Transfus Med 14 (2004) 375-383
75. Vamvakas E.C. Meta-analysis of randomized controlled trials comparing the risk of postoperative infection between recipients of allogeneic and autologous blood transfusion. Vox Sang 83 (2002) 339-346
76. Vamvakas E.C. Possible mechanisms of allogeneic blood transfusion-associated postoperative infection. Transfus Med Rev 16 (2002) 144-160
77. Fergusson D., Khanna M.P., Tinmouth A., and Hebert P.C. Transfusion of leukoreduced red blood cells may decrease postoperative infections: two meta-analyses of randomized controlled trials. Can J Anaesth 51 (2004) 417-424
78. Vamvakas E.C. WBC-containing allogeneic blood transfusion and mortality: a meta-analysis of randomized controlled trials. Transfusion 43 (2003) 963-973
79. Walsh T.S., McArdle F., McLellan S.A., et al. Does the storage time of transfused red blood cells influence regional or global indexes of tissue oxygenation in anemic critically ill patients?. Crit Care Med 32 (2004) 364-371
80. Kemming G.I., Meisner F.G., Kleen M., and Habler O.P. Calculation is unsuitable for determination of O2-consumption (VO2) in case of O2-supply-dependency. Eur J Med Res 7 (2002) 139-148
81. Torres Filho I.P., Spiess B.D., Pittman R.N., Barbee R.W., and Ward K.R. Experimental analysis of critical oxygen delivery. Am J Physiol Heart Circ Physiol 288 (2005) H1071-H1079
82. Paone G., and Silverman N.A. The paradox of on-bypass transfusion thresholds in blood conservation. Circulation 96 Suppl 2 (1997) 205-208
83. Sehgal L.R., Zebala L.P., Curran R.D., Votapka T.V., and Caprini J.A. Evaluation of oxygen extraction ratio as a physiologic transfusion trigger in coronary artery bypass graft surgery patients. Transfusion 41 (2001) 591-595