Stabilization mechanism of clarithromycin tablets under gastric pH conditions

Chemical and Pharmaceutical Bulletin

Volumn 59, Issue 5, 2011, Pages 553-558

  Fujiki, Sadahiro ^a   Iwao, Yasunori ^a   Kobayashi, Mika ^a   Miyagishima, Atsuo ^a   Itai, Shigeru ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Clarithromycin; Decomposition rate; Dissolution rate; Gelation

Indexed keywords

CLARITHROMYCIN; HYDROCHLORIC ACID;

ARTICLE; DRUG DECOMPOSITION; DRUG HALF LIFE; DRUG SOLUBILITY; DRUG STABILITY; GEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SIMULATION; STOMACH PH; TABLET DISINTEGRATION TIME; TABLET FORMULATION; X RAY DIFFRACTION;

ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLARITHROMYCIN; DRUG STABILITY; GASTRIC JUICE; GELS; HYDROGEN-ION CONCENTRATION; TABLETS; TIME FACTORS; X-RAY DIFFRACTION;

EID: 79955601972     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.59.553     Document Type: Article

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