Kinetic analysis of in vitro and in vivo release of prednisolone from the conjugate of glycol-chitosan and succinyl-prednisolone

International Journal of Pharmaceutics

Volumn 410, Issue 1-2, 2011, Pages 17-22

  Onishi, Hiraku ^a   Saito, Yuta ^a   Sasatsu, Masanaho ^a   MacHida, Yoshiharu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Conjugate; Drug release; Glycol chitosan; Plasma concentration; Prednisolone

Indexed keywords

GLYCOL CHITOSAN; PREDNISOLONE; SUCCINYL PREDNISOLONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG EFFECT; DRUG RELEASE; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PH; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; AREA UNDER CURVE; CHITOSAN; DELAYED-ACTION PREPARATIONS; DRUG STABILITY; EXCIPIENTS; HYDROGEN-ION CONCENTRATION; INJECTIONS, INTRAVENOUS; MALE; PREDNISOLONE; RATS; RATS, WISTAR;

EID: 79955598845     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.03.004     Document Type: Article

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