Yin and Yang in medicinal chemistry: What does drug-likeness mean?

Future Medicinal Chemistry

Volumn 3, Issue 5, 2011, Pages 505-507

  MacArrón, Ricardo ^a   Luengo, Juan I ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

drug like; lead like; natural products; oral drugs; rule of five

Indexed keywords

CYCLOSPORIN A; ERYTHROMYCIN; IVERMECTIN; NATURAL PRODUCT; NAVELBINE; PACLITAXEL; RAPAMYCIN; RIFAMPICIN; SMALL MOLECULE DRUG; TACROLIMUS; UNCLASSIFIED DRUG;

CHEMICAL COMPOSITION; CHEMISTRY; DRUG BIOAVAILABILITY; DRUG INDUSTRY; DRUG PENETRATION; DRUG RESEARCH; HUMAN; MEDICINAL CHEMISTRY; MOLECULARLY TARGETED THERAPY; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION;

BIOLOGICAL PRODUCTS; CHEMISTRY, PHARMACEUTICAL; DRUG DISCOVERY; PHARMACEUTICAL PREPARATIONS;

EID: 79955591890     PISSN: 17568919     EISSN: None     Source Type: Journal    
DOI: 10.4155/fmc.11.19     Document Type: Review

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