L-boronophenylalanine-mediated boron neutron capture therapy for malignant glioma progressing after external beam radiation therapy: A phase i study

International Journal of Radiation Oncology Biology Physics

Volumn 80, Issue 2, 2011, Pages 369-376

  Kankaanranta, Leena ^a   Seppälä, Tiina ^a,b,c   Koivunoro, Hanna ^a,b,c   Välimäki, Petteri ^b,c   Beule, Annette ^a   Collan, Juhani ^a   Kortesniemi, Mika ^a   Uusi Simola, Jouni ^a,b   Kotiluoto, Petri ^d   Auterinen, Iiro ^d   Sern, Tom ^d   Paetau, Anders ^a   Saarilahti, Kauko ^a   Savolainen, Sauli ^a,b   Joensuu, Heikki ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c Boneca Corporation   (Finland)

^d VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

Author keywords

Anaplastic astrocytoma; Boron neutron capture therapy; Boronophenylalanine; Brain tumor; Glioblastoma

Indexed keywords

ANAPLASTIC ASTROCYTOMA; BORON NEUTRON CAPTURE THERAPY; BORONOPHENYLALANINE; BRAIN TUMOR; GLIOBLASTOMAS;

BORON; BORON COMPOUNDS; NEUTRONS; PATIENT MONITORING; RADIOTHERAPY; SURGERY; TUMORS;

NEUTRON IRRADIATION;

4 BORONOPHENYLALANINE; LOMUSTINE; PROCARBAZINE; TEMOZOLOMIDE;

ADULT; AGED; ALOPECIA; AMNESIA; ARTICLE; BLURRED VISION; BRAIN EDEMA; CANCER RADIOTHERAPY; CANCER SURGERY; CLINICAL ARTICLE; COGNITIVE DEFECT; DRUG DOSE ESCALATION; DRY EYE; DUODENUM ULCER; EXTERNAL BEAM RADIOTHERAPY; FATIGUE; FEMALE; GLAUCOMA; GLIOBLASTOMA; HEADACHE; HUMAN; HYPERTENSION; INSOMNIA; MALE; MOTOR NEUROPATHY; MUSCLE WEAKNESS; NEUTRON CAPTURE THERAPY; OPEN STUDY; ORBIT EDEMA; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SEIZURE; SEROUS OTITIS MEDIA; SKIN ATROPHY; SKIN EDEMA; SOMNOLENCE; SPEECH DISORDER; TELANGIECTASIA; TREATMENT FAILURE; TREATMENT INDICATION; TREATMENT PLANNING; VOMITING; XEROSTOMIA;

ADULT; AGED; ASTROCYTOMA; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; BRAIN NEOPLASMS; DISEASE PROGRESSION; FEMALE; FRUCTOSE; GLIOBLASTOMA; HUMANS; MALE; MAXIMUM TOLERATED DOSE; MIDDLE AGED; RADIATION-SENSITIZING AGENTS; RADIOTHERAPY DOSAGE; YOUNG ADULT;

EID: 79955580430     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.02.031     Document Type: Article

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