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Volumn 30, Issue 2, 2011, Pages 162-173

Differences in rat models used in routine toxicity studies

Author keywords

control data; Hannover Wistar; in life data; neoplastic lesions; nonneoplastic lesions; rat strains; RccHan:WIST

Indexed keywords

ADRENAL GLAND; ANIMAL HOUSING; ANIMAL MODEL; ARTICLE; BIOCHEMISTRY; BODY WEIGHT; BREEDING; CARCINOGENICITY; CARDIOMYOPATHY; EYE INJURY; FOOD INTAKE; GENETIC VARIABILITY; HEMATOLOGY; INCIDENCE; LIVER INJURY; MAMMARY GLAND; MINERALIZATION; NONHUMAN; ONSET AGE; OPHTHALMOSCOPY; RAT STRAIN; SPRAGUE DAWLEY RAT; SURVIVAL; TOXICITY; UTERUS DISEASE; WISTAR RAT;

EID: 79955576802     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581810391818     Document Type: Article
Times cited : (51)

References (51)
  • 1
    • 22244437298 scopus 로고    scopus 로고
    • Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program
    • DOI 10.1080/01926230590961836
    • Brix AE, Nyska A, Haseman JK, Sells SM, Jokinen MP, Walker NJ. Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program. Toxicol Pathol. 2005 ; 33 (4). 477-483 (Pubitemid 40995487)
    • (2005) Toxicologic Pathology , vol.33 , Issue.4 , pp. 477-483
    • Brix, A.E.1    Nyska, A.2    Haseman, J.K.3    Sells, D.M.4    Jokinen, M.P.5    Walker, N.J.6
  • 2
    • 0031955224 scopus 로고    scopus 로고
    • 1 mice in two-year carcinogenicity studies: A national toxicology program update
    • Haseman JK, Hailey JR, Morris RW. Spontaneous neoplasm incidences in Fischer 344 rats and B6C3F1 mice in two-year carcinogenicity studies: a National Toxicology Program update. Toxicol Pathol. 1998 ; 26 (3). 428-441 (Pubitemid 28224283)
    • (1998) Toxicologic Pathology , vol.26 , Issue.3 , pp. 428-441
    • Haseman, J.K.1    Hailey, J.R.2    Morris, R.W.3
  • 3
    • 0031753238 scopus 로고    scopus 로고
    • Spontaneous neoplasms in control wistar rats: A comparison of reviews
    • DOI 10.1006/toxs.1998.2493
    • Poteracki J, Walsh KM. Spontaneous neoplasms in control Wistar rats: a comparison of reviews. Toxicol Sci. 1998 ; 45 (1). 1-8 (Pubitemid 28492233)
    • (1998) Toxicological Sciences , vol.45 , Issue.1 , pp. 1-8
    • Poteracki, J.1    Walsh, K.M.2
  • 5
    • 0029005870 scopus 로고
    • Incidence of nonneoplastic lesions in historical control male and female Fischer-344 rats from 90-day toxicity studies
    • Dixon D, Heider K, Elwell MR. Incidence of nonneoplastic lesions in historical control male and female Fischer-344 rats from 90-day toxicity studies. Toxicol Pathol. 1995 ; 23 (3). 338-348
    • (1995) Toxicol Pathol , vol.23 , Issue.3 , pp. 338-348
    • Dixon, D.1    Heider, K.2    Elwell, M.R.3
  • 6
    • 0031727857 scopus 로고    scopus 로고
    • The incidence of chronic progressive nephrosis in young Sprague-Dawley rats from two different breeders
    • Palm M. The incidence of chronic progressive nephrosis in young Sprague-Dawley rats from two different breeders. Lab Anim. 1998 ; 32 (4). 477-482 (Pubitemid 28482483)
    • (1998) Laboratory Animals , vol.32 , Issue.4 , pp. 477-482
    • Palm, M.1
  • 7
    • 79955603525 scopus 로고    scopus 로고
    • http://www.criver.com/SiteCollectionDocuments/rm-rm-r-Wistar-Han-clin- parameters-08.pdf
  • 8
    • 79955583209 scopus 로고    scopus 로고
    • http://www.criver.com/SiteCollectionDocuments/rm-rm-r-survival-wistar- han-rats-compilation-data.pdf
  • 9
    • 79955632406 scopus 로고    scopus 로고
    • http://www.criver.com/en-US/ProdServ/ByType/ResModOver/ResMod/Pages/ CDRat.aspx
  • 10
    • 79955640018 scopus 로고    scopus 로고
    • http://www.taconic.com/userassets/Documents/Products%20and%20Services/ Animal%20Models/Wistar-Hannover-data.pdf
  • 11
  • 12
    • 79955576592 scopus 로고    scopus 로고
    • http://www.harlan.com/research-models-and-services/research-models-by- product-type/outbred-rats/wistar-hannover.hl
  • 13
  • 15
    • 0008047821 scopus 로고
    • A systematic method of breeder rotation for non-inbred laboratory animal colonies
    • Poiley SM. A systematic method of breeder rotation for non-inbred laboratory animal colonies. Proc Anim Care Panel. 1960 ; 10 (4). 159-166
    • (1960) Proc Anim Care Panel , vol.10 , Issue.4 , pp. 159-166
    • Poiley, S.M.1
  • 16
    • 0037159633 scopus 로고    scopus 로고
    • Mutant Taiep rats exhibit an increase in D1 binding in basal ganglia
    • DOI 10.1016/S0006-8993(02)03434-0, PII S0006899302034340
    • Flores G, Flores J, Mena R, Valencia J. Mutant Taiep rats exhibit an increase in D1 binding in basal ganglia. Brain Res. 2002 ; 956 (1). 24-29 (Pubitemid 35335552)
    • (2002) Brain Research , vol.956 , Issue.1 , pp. 24-29
    • Flores, G.1    Flores, J.2    Mena, R.3    Valencia, J.4
  • 17
    • 0027631091 scopus 로고
    • Historical control data of organ weight and gross findings in F344/DuCrj rats and B6C3F1 mice
    • Iwata HT, Hagiwara M, Katoh S, et al. Historical control data of organ weight and gross findings in F344/DuCrj rats and B6C3F1 mice. Jikken Dobutsu. 1993 ; 42 (3). 383-396
    • (1993) Jikken Dobutsu , vol.42 , Issue.3 , pp. 383-396
    • Iwata, H.T.1    Hagiwara, M.2    Katoh, S.3
  • 18
    • 33845793368 scopus 로고    scopus 로고
    • Histological investigation of diagnostically challenging tubule profiles in advanced chronic progressive nephropathy (CPN) in the fischer 344 RaT
    • DOI 10.1080/01926230601083381, PII J5318T6003LGK6W4
    • Hard GC, Seely JC. Histological investigation of diagnostically challenging tubule profiles in advanced chronic progressive nephropathy (CPN) in the Fischer 344 rat. Toxicol Pathol. 2006 ; 34 (7). 941-948 (Pubitemid 46011146)
    • (2006) Toxicologic Pathology , vol.34 , Issue.7 , pp. 941-948
    • Hard, G.C.1    Seely, J.C.2
  • 19
    • 1842563805 scopus 로고    scopus 로고
    • A contemporary overview of chronic progressive nephropathy in the laboratory rat, and its significance for human risk assessment
    • DOI 10.1080/01926230490422574
    • Hard GC, Khan KN. A contemporary overview of chronic progressive nephropathy in the laboratory rat, and its significance for human risk assessment. Toxicol Pathol. 2004 ; 32 (2). 171-180 (Pubitemid 38437546)
    • (2004) Toxicologic Pathology , vol.32 , Issue.2 , pp. 171-180
    • Hard, G.C.1    Khan, K.N.2
  • 21
    • 0034102231 scopus 로고    scopus 로고
    • The relative protective effects of moderate dietary restriction versus dietary modification on spontaneous cardiomyopathy in male Sprague-Dawley rats
    • Kemi M, Keenan KP, McCoy C, et al. The relative protective effects of moderate dietary restriction versus dietary modification on spontaneous cardiomyopathy in male Sprague-Dawley rats. Toxicol Pathol. 2000 ; 28 (2). 285-296 (Pubitemid 30173836)
    • (2000) Toxicologic Pathology , vol.28 , Issue.2 , pp. 285-296
    • Kemi, M.1    Keenan, K.P.2    McCoy, C.3    Hoe, C.-M.4    Soper, K.A.5    Ballam, G.C.6    Van Zwieten, M.J.7
  • 23
    • 79955575879 scopus 로고    scopus 로고
    • Investigations on Corneal Pathology in RccHanTM: WIST Rats and Comparison with other Rat Strains (Report No. 200809 WEK, Harlan Laboratories Study Number C65377)
    • Weber K. Investigations on Corneal Pathology in RccHanTM: WIST Rats and Comparison with other Rat Strains (Report No. 200809 WEK, Harlan Laboratories Study Number C65377). Internal report. 2010 ;:
    • (2010) Internal Report
    • Weber, K.1
  • 24
    • 0024938605 scopus 로고
    • Morphological and stereological characterization of hepatic foci of cellular alteration in control Fischer 344 rats
    • Harada T, Maronpot RR, Morris RW, Stitzel KA, Boorman GA. Morphological and stereological characterization of hepatic foci of cellular alteration in control Fischer 344 rats. Toxicol Pathol. 1989 ; 17 (4 pt 1). 579-593 (Pubitemid 20125237)
    • (1989) Toxicologic Pathology , vol.17 , Issue.4 , pp. 579-593
    • Harada, T.1    Maronpont, R.R.2    Morris, R.W.3    Stitzel, K.A.4    Boorman, G.A.5
  • 26
    • 0037255302 scopus 로고    scopus 로고
    • Significance of hepatic preneoplasia in risk identification and early detection of neoplasia
    • DOI 10.1080/01926230309740
    • Bannasch P, Haertel T, Su Q. Significance of hepatic preneoplasia in risk identification and early detection of neoplasia. Toxicol Pathol. 2003 ; 31 (1). 134-139 (Pubitemid 36169431)
    • (2003) Toxicologic Pathology , vol.31 , Issue.1 , pp. 134-139
    • Bannasch, P.1    Haertel, T.2    Su, Q.3
  • 27
    • 0024910273 scopus 로고
    • Documenting foci of hepatocellular alteration in two-year carcinogenicity studies: Current practices of the National Toxicology Program
    • Maronpot RR, Harada T, Murthy AS, Boorman GA. Documenting foci of hepatocellular alteration in two-year carcinogenicity studies: current practices of the National Toxicology Program. Toxicol Pathol. 1989 ; 17 (4 pt 1). 675-683
    • (1989) Toxicol Pathol , vol.17 , Issue.4 PART 1 , pp. 675-683
    • Maronpot, R.R.1    Harada, T.2    Murthy, A.S.3    Boorman, G.A.4
  • 28
    • 0003645125 scopus 로고
    • Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
    • Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies). Natl Toxicol Program Tech Rep Ser. 1993 ; 422: 1-340
    • (1993) Natl Toxicol Program Tech Rep ser , vol.422 , pp. 1-340
  • 29
    • 80054871510 scopus 로고    scopus 로고
    • Toxicology and Carcinogenesis Studies of alpha-Methylstyrene (CAS No. 98-83-9) in F344/N Rats and B6C3F1 Mice (Inhalation studies)
    • Toxicology and Carcinogenesis Studies of alpha-Methylstyrene (CAS No. 98-83-9) in F344/N Rats and B6C3F1 Mice (Inhalation studies). Natl Toxicol Program Tech Rep Ser. 2007 ; 543: 1-210
    • (2007) Natl Toxicol Program Tech Rep ser , vol.543 , pp. 1-210
  • 31
    • 0024890554 scopus 로고
    • Evaluation and grading of rat liver foci in carcinogenicity tests
    • Squire RA. Evaluation and grading of rat liver foci in carcinogenicity tests. Toxicol Pathol. 1989 ; 17 (4 pt 1). 685-689 (Pubitemid 20125246)
    • (1989) Toxicologic Pathology , vol.17 , Issue.4 , pp. 685-689
    • Squire, R.A.1
  • 32
    • 0033858384 scopus 로고    scopus 로고
    • Two-year toxicity and carcinogenicity study of methyleugenol in F344/N rats and B6C3F1 mice
    • Johnson JD, Ryan MJ, Toft JD II, et al. Two-year toxicity and carcinogenicity study of methyleugenol in F344/N rats and B6C3F1 mice. J Agric Food Chem. 2000 ; 48 (8). 3620-3632
    • (2000) J Agric Food Chem , vol.48 , Issue.8 , pp. 3620-3632
    • Johnson, J.D.1    Ryan, M.J.2    Toft, J.D.I.I.3
  • 33
    • 0027729398 scopus 로고
    • Bile duct proliferation - Its true significance?
    • Burt AD, MacSween RN. Bile duct proliferation-its true significance?. Histopathology. 1993 ; 23 (6). 599-602 (Pubitemid 24034839)
    • (1993) Histopathology , vol.23 , Issue.6 , pp. 599-602
    • Burt, A.D.1    MacSween, R.N.M.2
  • 35
    • 84928699109 scopus 로고    scopus 로고
    • Toxicology and Carcinogenesis Studies of 2,3,4,7,8- Pentachlorodibenzofuran (PeCDF) (CAS No. 57117-31-4) in Female Harlan Sprague-Dawley Rats (Gavage Studies)
    • Toxicology and Carcinogenesis Studies of 2,3,4,7,8- Pentachlorodibenzofuran (PeCDF) (CAS No. 57117-31-4) in Female Harlan Sprague-Dawley Rats (Gavage Studies). Natl Toxicol Program Tech Rep Ser. 2006 ; 525: 1-198
    • (2006) Natl Toxicol Program Tech Rep ser , vol.525 , pp. 1-198
  • 36
    • 84925548152 scopus 로고    scopus 로고
    • Toxicology and Carcinogenesis Studies of a Mixture of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) (CAS No. 1746-01-6), 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CAS No. 57117-31-4), and 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in Female Harlan Sprague-Dawley Rats (Gavage Studies). NTP Study Reports
    • Toxicology and Carcinogenesis Studies of a Mixture of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) (CAS No. 1746-01-6), 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CAS No. 57117-31-4), and 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in Female Harlan Sprague-Dawley Rats (Gavage Studies). NTP Study Reports. Natl Toxicol Program Tech Rep Ser. 2006 ; 526: 1-180
    • (2006) Natl Toxicol Program Tech Rep ser , vol.526 , pp. 1-180
  • 37
    • 23044493444 scopus 로고    scopus 로고
    • Morphological and endocrinological characteristics of the endocrine systems in Wistar Hannover GALAS rats showing spontaneous dwarfs
    • Doi T, Namiki M, Ashina M, et al. Morphological and endocrinological characteristics of the endocrine systems in Wistar Hannover GALAS rats showing spontaneous dwarfs. J Toxicol Pathol. 2004 ; 17 (3). 187-203
    • (2004) J Toxicol Pathol , vol.17 , Issue.3 , pp. 187-203
    • Doi, T.1    Namiki, M.2    Ashina, M.3
  • 38
    • 35548978023 scopus 로고    scopus 로고
    • Morphological characteristics of bone in dwarf rats derived from Wistar Hannover GALAS rats
    • Kokoshima H, Doi T, Kurotaki T, Sato J, Kotani Y, Tsuchitani M. Morphological characteristics of bone in dwarf rats derived from Wistar Hannover GALAS rats. J Toxicol Pathol. 2007 ; 20 (3). 155-160
    • (2007) J Toxicol Pathol , vol.20 , Issue.3 , pp. 155-160
    • Kokoshima, H.1    Doi, T.2    Kurotaki, T.3    Sato, J.4    Kotani, Y.5    Tsuchitani, M.6
  • 41
    • 3242879065 scopus 로고    scopus 로고
    • Early occurrence of spontaneous tumors in CD-1 mice and Sprague-Dawley rats
    • DOI 10.1080/01926230490440871
    • Son WC, Gopinath C. Early occurrence of spontaneous tumors in CD-1 mice and Sprague-Dawley rats. Toxicol Pathol. 2004 ; 32 (4). 371-374 (Pubitemid 38998928)
    • (2004) Toxicologic Pathology , vol.32 , Issue.4 , pp. 371-374
    • Son, W.-C.1    Gopinath, C.2
  • 43
    • 0028120357 scopus 로고
    • Neoplastic lesions of questionable significance to humans
    • Alison RH, Capen CC, Prentice DE. Neoplastic lesions of questionable significance to humans. Toxicol Pathol. 1994 ; 22 (2). 179-186 (Pubitemid 24230961)
    • (1994) Toxicologic Pathology , vol.22 , Issue.2 , pp. 179-186
    • Alison, R.H.1    Capen, C.C.2    Prentice, D.E.3
  • 44
    • 0037190117 scopus 로고    scopus 로고
    • On the occurrence of Leydig cell tumors in the F344 rat
    • DOI 10.1016/S0304-3835(01)00865-5, PII S0304383501008655
    • Weisburger JH, Rivenson A, Reinhardt J, Braley J, Pittman B, Zang E. On the occurrence of Leydig cell tumors in the F344 rat. Cancer Lett. 2002 ; 182 (2). 213-216 (Pubitemid 34621185)
    • (2002) Cancer Letters , vol.182 , Issue.2 , pp. 213-216
    • Weisburger, J.H.1    Rivenson, A.2    Reinhardt, J.3    Braley, J.4    Pittman, B.5    Zang, E.6
  • 45
    • 0029109953 scopus 로고
    • Interstitial cell adenoma of the rat testis: Why is it such a problem in toxicology studies using Sprague-Dawley rats?
    • Davis TE. Interstitial cell adenoma of the rat testis: why is it such a problem in toxicology studies using Sprague-Dawley rats?. Toxicol Pathol. 1995 ; 23 (1). 83-86
    • (1995) Toxicol Pathol , vol.23 , Issue.1 , pp. 83-86
    • Davis, T.E.1
  • 46
    • 0029160082 scopus 로고
    • Spontaneous vascular neoplasms in aged Sprague-Dawley rats
    • Zwicker GM, Eyster RC, Sells DM, Gass JH. Spontaneous vascular neoplasms in aged Sprague-Dawley rats. Toxicol Pathol. 1995 ; 23 (4). 518-526
    • (1995) Toxicol Pathol , vol.23 , Issue.4 , pp. 518-526
    • Zwicker, G.M.1    Eyster, R.C.2    Sells, D.M.3    Gass, J.H.4
  • 47
    • 0028910672 scopus 로고
    • Proliferating cell nuclear antigen staining of Fischer-344/N rat spleens affected by large granular lymphocyte leukemia
    • Stefanski SA, Greenwell A, Merrick BA, Brown TT, Reynolds SH. Proliferating cell nuclear antigen staining of Fischer-344/N rat spleens affected by large granular lymphocyte leukemia. Toxicol Pathol. 1995 ; 23 (1). 1-6
    • (1995) Toxicol Pathol , vol.23 , Issue.1 , pp. 1-6
    • Stefanski, S.A.1    Greenwell, A.2    Merrick, B.A.3    Brown, T.T.4    Reynolds, S.H.5
  • 50
    • 0026215156 scopus 로고
    • Ganglioneuromas of the thyroid gland in a colony of Sprague-Dawley rats
    • Crissman JW, Valerio MG, Asiedu SA, Evangelista-Sobel I. Ganglioneuromas of the thyroid gland in a colony of Sprague-Dawley rats. Vet Path. 1991 ; 28 (5). 354-362
    • (1991) Vet Path , vol.28 , Issue.5 , pp. 354-362
    • Crissman, J.W.1    Valerio, M.G.2    Asiedu, S.A.3    Evangelista-Sobel, I.4
  • 51
    • 0017127035 scopus 로고
    • Levels of spontaneous malformations in the CD rat and the CD-1 mouse
    • Perraud J. Levels of spontaneous malformations in the CD rat and the CD-1 mouse. Lab Anim Sci. 1976 ; 26 (2 pt 2). 293-300
    • (1976) Lab Anim Sci , vol.26 , Issue.2 PART 2 , pp. 293-300
    • Perraud, J.1


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