HHGF overexpression in myoblast sheets enhances their angiogenic potential in rat chronic heart failure

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  Siltanen, Antti ^a   Kitabayashi, Katsukiyo ^b   Lakkisto, Päivi ^c,d   Mäkelä, Johanna ^c   Pätilä, Tommi ^e   Ono, Masamichi ^b   Tikkanen, Ilkka ^c,d   Sawa, Yoshiki ^b   Kankuri, Esko ^a   Harjula, Ari ^e  

^a UNIVERSITY OF HELSINKI   (Finland)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^e UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

SCATTER FACTOR; VASCULOTROPIN; HGF PROTEIN, HUMAN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; AUTOCRINE EFFECT; CELL MIGRATION; CELL STRUCTURE; CELL THERAPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ECHOCARDIOGRAPHY; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GRAFT SURVIVAL; HEART FAILURE; HEART FUNCTION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MYOBLAST; MYOBLAST SHEET THERAPY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RAT; ANIMAL; APOPTOSIS; BIOASSAY; CELL LINE; CHRONIC DISEASE; ECHOGRAPHY; FIBROSIS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HEART FUNCTION TEST; HUMAN; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; VASODILATATION; WISTAR RAT;

RATTUS; RATTUS NORVEGICUS;

ANIMALS; APOPTOSIS; BIOLOGICAL ASSAY; CELL LINE; CHRONIC DISEASE; FIBROSIS; GENE EXPRESSION REGULATION; HEART FAILURE; HEART FUNCTION TESTS; HEPATOCYTE GROWTH FACTOR; HUMANS; MYOBLASTS; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, WISTAR; TRANSFECTION; VASODILATION;

EID: 79955575392     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019161     Document Type: Article

References (22)

1. Matsumoto K, Nakamura T, (1996) Emerging multipotent aspects of hepatocyte growth factor. J Biochem 119: 591-600.
2. Ueda H, Nakamura T, Matsumoto K, Sawa Y, Matsuda H, et al. (2001) A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats. Cardiovasc Res 51: 41-50.
3. Ono K, Matsumori A, Shioi T, Furukawa Y, Sasayama S, (1997) Enhanced expression of hepatocyte growth factor/c-Met by myocardial ischemia and reperfusion in a rat model. Circulation 95: 2552-2558.
4. Ueno S, Ikeda U, Hojo Y, Arakawa H, Nonaka M, et al. (2001) Serum hepatocyte growth factor levels are increased in patients with congestive heart failure. J Card Fail 7: 329-334.
5. Nakamura T, Mizuno S, Matsumoto K, Sawa Y, Matsuda H, et al. (2000) Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF. J Clin Invest 106: 1511-1519.
6. Krause K, Schneider C, Kuck KH, Jaquet K, (2010) REVIEW: Stem cell therapy in cardiovascular disorders. Cardiovasc Ther 28: 101-110.
7. Memon IA, Sawa Y, Fukushima N, Matsumiya G, Miyagawa S, et al. (2005) Repair of impaired myocardium by means of implantation of engineered autologous myoblast sheets. J Thorac Cardiovasc Surg 130: 1333-1341.
8. Hamdi H, Furuta A, Bellamy V, Bel A, Puymirat E, et al. (2009) Cell delivery: intramyocardial injections or epicardial deposition? A head-to-head comparison. Ann Thorac Surg 87: 1196-1203.
9. Kitabayashi K, Siltanen A, Pätilä T, Mahar MA, Tikkanen I, et al. (2010) Bcl-2 expression enhances myoblast sheet transplantation therapy for acute myocardial infarction. Cell Transplant 19: 573-588.
10. Siltanen A, Kitabayashi K, Pätilä T, Ono M, Tikkanen I, (2010) Bcl-2 Improves Myoblast Sheet Therapy in Rat Chronic Heart Failure. Tissue Eng Part A [Epub ahead of print].
11. Ahmet I, Sawa Y, Yamaguchi T, Matsuda H, (2003) Gene transfer of hepatocyte growth factor improves angiogenesis and function of chronic ischemic myocardium in canine heart. Ann Thorac Surg 75: 1283-1287.
12. Palojoki E, Saraste A, Eriksson A, Pulkki K, Kallajoki M, et al. (2001) Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats. Am J Physiol Heart Circ Physiol 280: H2726-2731.
13. Miller KJ, Thaloor D, Matteson S, Pavlath GK, (2000) Hepatocyte growth factor affects satellite cell activation and differentiation in regenerating skeletal muscle. Am J Physiol Cell Physiol 278: C174-181.
14. Aoki M, Morishita R, Taniyama Y, Kida I, Moriguchi A, et al. (2000) Angiogenesis induced by hepatocyte growth factor in non-infarcted myocardium and infarcted myocardium: up-regulation of essential transcription factor for angiogenesis, ets. Gene Ther 7: 417-427.
15. Zhang YW, Su Y, Volpert OV, Vande Woude GF, (2003) Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation. Proc Natl Acad Sci U S A 100: 12718-12723.
16. Tambara K, Premaratne GU, Sakaguchi G, Kanemitsu N, Lin X, et al. (2005) Administration of control-released hepatocyte growth factor enhances the efficacy of skeletal myoblast transplantation in rat infarcted hearts by greatly increasing both quantity and quality of the graft. Circulation 112: I129-134.
17. Perez-Ilzarbe M, Agbulut O, Pelacho B, Ciorba C, San Jose-Eneriz E, et al. (2008) Characterization of the paracrine effects of human skeletal myoblasts transplanted in infarcted myocardium. Eur J Heart Fail 10: 1065-1072.
18. Xin X, Yang S, Ingle G, Zlot C, Rangell L, et al. (2001) Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo. Am J Pathol 158: 1111-1120.
19. Wojakowski W, Tendera M, Zebzda A, Michalowska A, Majka M, et al. (2006) Mobilization of CD34(+), CD117(+), CXCR4(+), c-met(+) stem cells is correlated with left ventricular ejection fraction and plasma NT-proBNP levels in patients with acute myocardial infarction. Eur Heart J 27: 283-289.
20. Taniyama Y, Morishita R, Aoki M, Hiraoka K, Yamasaki K, et al. (2002) Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy. Hypertension 40: 47-53.
21. Nakamura T, Matsumoto K, Mizuno S, Sawa Y, Matsuda H, et al. (2005) Hepatocyte growth factor prevents tissue fibrosis, remodeling, and dysfunction in cardiomyopathic hamster hearts. Am J Physiol Heart Circ Physiol 288: H2131-2139.
22. Deten A, Hölzl A, Leicht M, Barth W, Zimmer HG, (2001) Changes in extracellular matrix and in transforming growth factor beta isoforms after coronary artery ligation in rats. J Mol Cell Cardiol 33: 1191-1207.