Microscreening toxicity system based on living magnetic yeast and gradient chips

Analytical and Bioanalytical Chemistry

Volumn 400, Issue 4, 2011, Pages 1009-1013

  García Alonso, Javier ^a,d   Fakhrullin, Rawil F ^b   Paunov, Vesselin N ^a   Shen, Zheng ^c   Hardege, Joerg D ^a   Pamme, Nicole ^a   Haswell, Stephen J ^a   Greenway, Gillian M ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

^b URAL FEDERAL UNIVERSITY   (Russian Federation)

^c DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^d DEPARTMENT OF LIFE SCIENCES   (United Kingdom)

Author keywords

GFP reporter yeast; Magnetic retention; Microfluidic devices; Toxicity screening

Indexed keywords

BIOMEDICAL RESEARCH; CELL TYPES; CHEMICAL MIXTURES; COST-EFFECTIVE METHODS; FLUORESCENT REPORTER; GENETICALLY MODIFIED; GENOTOXIC; GENOTOXICITIES; GFP REPORTER; GFP REPORTER YEAST; GREEN FLUORESCENT PROTEIN; MAGNETIC NANOPARTICLES; MAGNETIC RETENTION; MICROFLUIDIC CHIP; MICROFLUIDIC DEVICES; MICROSCREENING; MULTIPLE USE; POSITIVELY CHARGED; POTENTIAL APPLICATIONS; SCREENING METHODS; SCREENING TESTS; SYSTEM-BASED; TOXICOLOGICAL IMPACT; YEAST CELL;

BIOASSAY; FLUIDIC DEVICES; FLUORESCENCE; METHANE; MICROFLUIDICS; NANOMAGNETICS; NANOPARTICLES; YEAST;

TOXICITY;

GREEN FLUORESCENT PROTEIN;

ARTICLE; DOSE RESPONSE; GENETICS; INDUSTRIAL WASTE; INSTRUMENTATION; MAGNETISM; METABOLISM; METHODOLOGY; MICROFLUIDIC ANALYSIS; TOXICITY TESTING; YEAST;

DOSE-RESPONSE RELATIONSHIP, DRUG; GREEN FLUORESCENT PROTEINS; INDUSTRIAL WASTE; MAGNETICS; MICROFLUIDIC ANALYTICAL TECHNIQUES; TOXICITY TESTS; YEASTS;

EID: 79955568488     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-010-4241-3     Document Type: Article

References (18)

1. European Commission Regulation 2006 Regulation (EC) No 882/2004 of the European parliament and of the council as regards community reference laboratories Official J Eur Union L136 3 8
2. PR de Souza J Geibel 1999 Direct observation of oxidative stress on the cell wall of Saccharomyces cerevisiae strains with atomic force microscopy Mol Cell Biochem 201 17 24 10.1023/A:1007007704657 (Pubitemid 30019360)
3. PA Cahill AW Knight N Billinton MG Barker L Walsh PO Keenan CV Williams DJ Tweats RM Walmsley 2004 The GreenScreen genotoxicity assay: a screening validation programme Mutagenesis 19 105 119 10.1093/mutage/geh015 1:CAS:528:DC%2BD2cXhslWkt78%3D (Pubitemid 38380287)
4. E Michelini P Leskinen M Virta M Kart A Roda 2005 A new recombinant cell-based bioluminescent assay for sensitive androgen-like compound detection Biosens Bioelectron 20 2261 2267 10.1016/j.bios.2004.10.018 1:CAS:528: DC%2BD2MXis1Kjsr8%3D (Pubitemid 40431552)
5. JV VanGompel F Woestenborghs D Beerens C Mackie PA Cahill AW Knight N Billington DJ Tweats RM Walmsley 2005 An assessment of the utility of the yeast GreenScreen assay in pharmaceutical screening Mutagenesis 20 449 454 10.1093/mutage/gei062 1:CAS:528:DC%2BD2MXhtlagur%2FO (Pubitemid 41816532)
6. AW Knight PO Keenan NJ Goddard PR Fielden RM Walmsley 2004 A yeast-based cytotoxicity and genotoxicity assay for environmental monitoring using novel portable instrumentation J Environ Monitor 6 71 79 10.1039/b310206h 1:CAS:528:DC%2BD2cXhtFKkug%3D%3D (Pubitemid 38122124)
7. MP MacDonald GC Spalding K Dholakia 2003 Microfluidic sorting in an optical lattice Nature 426 421 424 10.1038/nature02144 1:CAS:528: DC%2BD3sXpt1GlsLo%3D (Pubitemid 37490125)
8. BS Cho TG Schuster X Zhu D Chang GD Smith S Takayama 2003 Passively driven integrated microfluidic system for separation of motile sperm Anal Chem 75 1671 1675 10.1021/ac020579e 1:CAS:528:DC%2BD3sXhtlCjs74%3D (Pubitemid 36512607)
9. SW Rhee AM Taylor CH Tu DH Cribbs CW Cotman NL Jeon 2004 Patterned cell culture inside microfluidic devices Lab Chip 5 102 107 10.1039/b403091e
10. HC Zeringue JJ Rutledge DJ Beebe 2004 Early mammalian embryo development depends on cumulus removal technique Lab Chip 5 86 90 10.1039/b316494m (Pubitemid 40139344)
11. A Tourovskaia X Figueroa-Masot A Folch 2004 Differentiation-on-a-chip: a microfluidic platform for long-term cell culture studies Lab Chip 5 14 19 10.1039/b405719h
12. AA Verdich EA Lima B Ivanov I Ges ME Anderson JP Wikswo FJ Baudenbacher 2004 A microfluidic device to confine a single cardiac myocyte in a sub-nanoliter volume on planar microelectrodes for extracellular potential recordings Lab Chip 4 357 362 10.1039/b315648f (Pubitemid 39150238)
13. PJ Hung PJ Lee P Sabounchi R Lin LP Lee 2005 Continuous perfusion microfluidic cell culture array for high-throughput cell-based assays Biotechnol Bioeng 89 1 8 10.1002/bit.20289 1:CAS:528:DC%2BD2MXltlShuw%3D%3D (Pubitemid 40110978)
14. J García-Alonso G Greenway J Hardege S Haswell 2009 A prototype microfluidic chip using fluorescent yeast for detection of toxic compounds Biosens Bioelectron 24 1508 1511 10.1016/j.bios.2008.07.074
15. N Ye J Qin W Shi X Liu B Lin 2007 Cell-based high content screening using an integrated microfluidic device Lab Chip 7 1696 1705 10.1039/b711513j 1:CAS:528:DC%2BD2sXhtlahtbfN (Pubitemid 350145540)
16. J García-Alonso RF Fakhrullin VN Paunov 2010 Rapid and direct magnetization of GFP-reporter yeast for micro-screening systems Biosens Bioelectron 25 1816 1819 10.1016/j.bios.2009.11.016
17. N Pamme 2006 Magnetism and microfluidics Lab Chip 6 1 24 38 10.1039/b513005k 1:CAS:528:DC%2BD2MXhtlakurjI
18. P Breeuwer J-L Drocourt N Bunschoten MC Zwietering FM Rombouts T Abee 1995 Characterization of uptake and hydrolysis of fluorescein diacetate and carboxyfluorescein diacetate by intracellular esterases in Saccharomyces cerevisiae, which result in accumulation of fluorescent product Appl Environ Microbiol 61 1614 1619 1:CAS:528:DyaK2MXksl2lt74%3D