Is small-bowel bacterial overgrowth an underdiagnosed disorder in children with gastrointestinal symptoms?

Journal of Pediatric Gastroenterology and Nutrition

Volumn 52, Issue 5, 2011, Pages 632-634

  Jones, Hilary F ^a   Davidson, Geoffrey P ^b   Brooks, Doug A ^a   Butler, Ross N ^a  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b WOMEN S AND CHILDREN S HOSPITAL   (Australia)

Author keywords

Breath hydrogen test; gastrointestinal disease; small bowel bacterial overgrowth

Indexed keywords

CARBOHYDRATE; LACTULOSE;

ADOLESCENT; ARTICLE; BACTERIAL OVERGROWTH; CARBOHYDRATE ABSORPTION; CHILD; CLINICAL ASSESSMENT; COHORT ANALYSIS; GASTROINTESTINAL SYMPTOM; HUMAN; HYDROGEN BREATH TEST; INFANT; MAJOR CLINICAL STUDY; MALABSORPTION; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SMALL BOWEL BACTERIAL OVERGROWTH;

ABDOMINAL PAIN; ADOLESCENT; BLIND LOOP SYNDROME; BREATH TESTS; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; DIAGNOSTIC ERRORS; HUMANS; HYDROGEN; INFANT; INTESTINE, SMALL; IRRITABLE BOWEL SYNDROME; LACTULOSE; MALABSORPTION SYNDROMES; RETROSPECTIVE STUDIES;

BACTERIA (MICROORGANISMS);

EID: 79955564731     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e31820d5c16     Document Type: Article

References (20)

1. de Boissieu D, Chaussain M, Badoual J, et al. Small-bowel bacterial overgrowth in children with chronic diarrhea, abdominal pain, or both. J Pediatr 1996;128:203-7. (Pubitemid 26065943)
2. Teo M, Chung S, Chitti L, et al. Small bowel bacterial overgrowth is a common cause of chronic diarrhea. J Gastroenterol Hepatol 2004; 19:904-9. (Pubitemid 39093208)
3. Davidson GP, Robb TA, Kirubakaran CP. Bacterial contamination of the small intestine as an important cause of chronic diarrhea and abdominal pain: diagnosis by breath hydrogen test. Pediatrics 1984; 74:229-35. (Pubitemid 14054164)
4. Scarpellini E, Giorgio V, Gabrielli M, et al. Prevalence of small intestinal bacterial overgrowth in children with irritable bowel syndrome: a case-control study. J Pediatr 2009;155:416-20.
5. Pimentel M, Chow EJ, Lin HC. Normalization of lactulose breath testing correlates with symptom improvement in irritable bowel syndrome. A double-blind, randomized, placebo-controlled study. Am J Gastroenterol 2003;98:412-9. (Pubitemid 36232393)
6. Khoshini R, Dai SC, Lezcano S, et al. A systematic review of diagnostic tests for small intestinal bacterial overgrowth. Dig Dis Sci 2008;53: 1443-54.
7. Davidson GP, Butler RN. Breath analysis. In: Kleinman RE, Goulet O, Mieli-Vergani G, et al, eds.Walker's Pediatric Gastrointestinal Disease. 5th ed. Sydney: McGraw-Hill; 2008:1411-7.
8. Lin HC. Small intestinal bacterial overgrowth: a framework for understanding irritable bowel syndrome. JAMA 2004;292:852-8. (Pubitemid 39079672)
9. Rhodes JM, Middleton P, Jewell DP. The lactulose hydrogen breath test as a diagnostic test for small-bowel bacterial overgrowth. Scand J Gastroenterol 1979;14:333-6. (Pubitemid 9185710)
10. Mendoza E, Crismatt C, Matos R, et al. Diagnosis of small intestinal bacterial overgrowth in children: the use of lactulose in the breath hydrogen test as a screening test. Biomedica 2007;27:325-32. (Pubitemid 351890520)
11. dos Reis JC, de Morais MB, Oliva CA, et al. Breath hydrogen test in the diagnosis of environmental enteropathy in children living in an urban slum. Dig Dis Sci 2007;52:1253-8. (Pubitemid 46626168)
12. Pereira SP, Khin Maung U, Bolin TD, et al. A pattern of breath hydrogen excretion suggesting small bowel bacterial overgrowth in Burmese village children. J Pediatr Gastroenterol Nutr 1991;13:32-8.
13. Collins BS, Lin HC. Chronic abdominal pain in children is associated with high prevalence of abnormal microbial fermentation. Dig Dis Sci 2010;55:124-30.
14. Ghoshal UC, Kumar S, Mehrotra M, et al. Frequency of small intestinal bacterial overgrowth in patients with irritable bowel syndrome and chronic non-specific diarrhea. J Neurogastroenterol Motil 2010;16:40-6.
15. Shah ED, Basseri RJ, Chong K, et al. Abnormal breath testing in IBS: a meta-analysis. Dig Dis Sci 2010;55:2441-9.
16. Pimentel M, Kong Y, Park S. Breath testing to evaluate lactose intolerance in irritable bowel syndrome correlates with lactulose testing and may not reflect true lactose malabsorption. Am J Gastroenterol 2003;98:2700-4. (Pubitemid 38020111)
17. Zhao J, Fox M, Cong Y, et al. Lactose intolerance in patients with chronic functional diarrhoea: the role of small intestinal bacterial overgrowth. Aliment Pharmacol Ther 2010;31:892-900.
18. Nucera G, Gabrielli M, Lupascu A, et al. Abnormal breath tests to lactose, fructose and sorbitol in irritable bowel syndrome may be explained by small intestinal bacterial overgrowth. Aliment Pharmacol Ther 2005;21:1391-5. (Pubitemid 40813686)
19. Attar A, Flourie B, Rambaud JC, et al. Antibiotic efficacy in small intestinal bacterial overgrowth-related chronic diarrhea: a crossover, randomized trial. Gastroenterology 1999;117:794-7. (Pubitemid 29468220)
20. Di Stefano M, Strocchi A, Malservisi S, et al. Non-absorbable antibiotics for managing intestinal gas production and gas-related symptoms. Aliment Pharmacol Ther 2000;14:1001-8. (Pubitemid 30618160)